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Molecular Nutrition & Food Research, ISSN 1613-4125, 08/2019, Volume 63, Issue 16, pp. e1801143 - n/a
Nutritional studies are greatly hampered by a paucity of proper models. Previous studies on nutrition have employed conventional cell lines and animal models... 
location‐specific functions | enteroid models | intestinal stem cells | intestinal barriers | nutrient transport | HUMAN COLON | STEM-CELLS | FOOD SCIENCE & TECHNOLOGY | MICROBIOTA | INTESTINAL BARRIER FUNCTION | RAT MODEL | ORGANOIDS | PIG | IN-VITRO | CULTURE-SYSTEM | AMINO-ACIDS | location-specific functions | Analysis | Stem cells | College teachers
Journal Article
Drug Discovery Today, ISSN 1359-6446, 09/2019, Volume 24, Issue 9, pp. 1784 - 1794
Until recently, major advances in drug development have been hampered by a lack of proper cell and tissue models; but the introduction of organoid technology... 
HUMAN COLON | EPITHELIAL ORGANOIDS | IN-VITRO | STEM-CELLS | REPLICATION | ROTAVIRUS INFECTION | PHARMACOLOGY & PHARMACY | INTESTINAL ORGANOIDS | SUPPRESSION | EXPRESSION | CFTR | Drugs | Analysis | Communicable diseases | Gastrointestinal system | Stem cells | Cystic fibrosis | Livestock
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2015, Volume 10, Issue 2
The cause of Cystic fibrosis liver disease (CFLD), is unknown. It is well recognized that hepatic exposure to hydrophobic bile salts is associated with the... 
TRANSMEMBRANE CONDUCTANCE REGULATOR | MDR2 | BILE-SALTS | RAT | DUCT EPITHELIAL-CELLS | DISEASE | CYSTIC-FIBROSIS MOUSE | FARNESOID-X RECEPTOR | MODEL | P-GLYCOPROTEIN GENE
Journal Article
Yale Journal of Biology and Medicine, ISSN 0044-0086, 12/2015, Volume 88, Issue 4, pp. 367 - 374
Organoids have tremendous therapeutic potential. They were recently defined as a collection of organ-specific cell types, which self-organize through... 
Squalus acanthias | Cystic fibrosis | Organoids | Danio rerio | Fundulus heteroclitus | Organoids - physiology | Epithelium - drug effects | Animals | Models, Biological | Humans | Organoids - drug effects | Zebrafish | Epithelium - physiology | Fundulidae | Precision Medicine
Journal Article
Yale Journal of Biology and Medicine, ISSN 0044-0086, 11/2015, Volume 88, Issue 4, pp. 367 - 374
Organoids have tremendous therapeutic potential. They were recently defined as a collection of organ-specific cell types, which self-organize through... 
Journal Article
Nature Medicine, ISSN 1078-8956, 2013, Volume 19, Issue 7, pp. 939 - 945
Journal Article
Journal Article
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, ISSN 0363-6143, 10/2019, Volume 317, Issue 4, pp. C737 - C748
Journal Article
International Journal of Biochemistry and Cell Biology, ISSN 1357-2725, 07/2014, Volume 52, pp. 192 - 200
Journal Article
American Journal of Physiology: Cell Physiology, ISSN 0363-6143, 02/2014, Volume 306, Issue 4, pp. 343 - 343
The in vitro perfused rectal gland of the dogfish shark (Squalus acanthias) and filter-grown monolayers of primary cultures of shark rectal gland (SRG)... 
Journal Article
Journal Article
American Journal of Physiology-Gastrointestinal and Liver Physiology, ISSN 0193-1857, 05/2012, Volume 302, Issue 9, pp. G1035 - G1042
Bodewes FAJA, Wouthuyzen-Bakker M, Bijvelds MJ, Havinga R, de Jonge HR, Verkade HJ. Ursodeoxycholate modulates bile flow and bile salt pool independently from... 
CHOLIC-ACID | mouse model | CHOLESTEROL | CONDUCTANCE REGULATOR | CHOLESTATIC LIVER-DISEASE | ACID KINETICS | DEFICIENT MICE | ENTEROHEPATIC CIRCULATION | cystic fibrosis liver disease | UMCG Approved | ursodeoxycholic acid | SECRETION | ISOTOPE-DILUTION | bile salt kinetics | PRIMARY SCLEROSING CHOLANGITIS
Journal Article