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1. Full Text First person profile: Albert de la Chapelle, MD, PhD Known for several pioneering discoveries in genetics, Dr. de la Chapelle is working to shed light on the genes that cause thyroid cancer
by Printz, C and de la Chapelle, A
CANCER, ISSN 0008-543X, 10/2019, Volume 125, Issue 19, pp. 3285 - 3286
ONCOLOGY
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2. Full Text Cancer germline genetics: The unbelievable year 1993 and thereafter
by De La Chapelle, Albert
Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14, pp. 4025 - 4027
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3. L'Écriture, âme de la théologie
: la parole et le langage chez Albert Chapelle
by Baenst, Benoît de
2014, Collège des Bernardins. Essai, ISBN 9782889182985, 786
Chapelle, Albert | Catholic Church Doctrines | Bible Criticism, interpretation, etc
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4. Full Text Colon Cancer Germline Genetics: The Unbelievable Year 1993 and Thereafter
by de la Chapelle, A
CANCER RESEARCH, ISSN 0008-5472, 07/2016, Volume 76, Issue 14, pp. 4025 - 4027
HOMOLOG | MUTATIONS | ONCOLOGY | MICROSATELLITE INSTABILITY | Germ-Line Mutation | Colonic Neoplasms - genetics | Colonic Neoplasms - history | History, 20th Century | Humans
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5. Full Text HABP2 Mutation and Nonmedullary Thyroid Cancer
by Tomsic, Jerneja and He, Huiling and de la Chapelle, Albert
The New England journal of medicine, ISSN 0028-4793, 11/2015, Volume 373, Issue 21, pp. 2086 - 2086
MEDICINE, GENERAL & INTERNAL | Thyroid Neoplasms - genetics | Adenoma - genetics | Humans | Serine Endopeptidases - genetics | Germ-Line Mutation | Female | Male | Neoplastic Syndromes, Hereditary - genetics
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6. The Olympic Games and Athletic Sex Assignment
by Genel, Myron and Simpson, Joe Leigh and de la Chapelle, Albert
JAMA: Journal of the American Medical Association, ISSN 0098-7484, 10/2016, Volume 316, Issue 13, pp. 1359 - 1359
At least 2 women athletes subjected to intense media scrutiny in the past several years--Caster Semenya and Dutee Chand--are likely to attract additional... 
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7. Full Text MYH9 binds to lncRNA gene PTCSC2 and regulates FOXE 1 in the 9q22 thyroid cancer risk locus
by Wang, Yanqiang and He, Huiling and Li, Wei and Phay, John and Shen, Rulong and Yu, Lianbo and Hancioglu, Baris and De La Chapelle, Albert
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 01/2017, Volume 114, Issue 3, pp. 474 - 479
LncRNA | Bidirectional promoter | MYH9 | Thyroid cancer | Transcriptional regulation
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8. Full Text Variants in microRNA genes in familial papillary thyroid carcinoma
by Tomsic, Jerneja and Fultz, Rebecca and Liyanarachchi, Sandya and Genutis, Luke K and Wang, Yanqiang and Li, Wei and Volinia, Stefano and Jazdzewski, Krystian and He, Huiling and Wakely, Paul E and Senter, Leigha and de la Chapelle, Albert
Oncotarget, ISSN 1949-2553, 2017, Volume 8, Issue 4, pp. 6475 - 6482
Papillary Thyroid Carcinoma (PTC) displays one of the highest familiality scores of all cancers as measured by case-control studies, yet only a handful of... 
Variants | Genetics | MiRNA | Predisposition | Thyroid | COMMON VARIANTS | genetics | thyroid | predisposition | miRNA | variants | CANCER | CELL BIOLOGY | Carcinoma, Papillary - genetics | Humans | Gene Expression Regulation, Neoplastic | Cercopithecus aethiops | MicroRNAs - metabolism | Carcinoma, Papillary - metabolism | Genetic Variation | Transfection | HEK293 Cells | Biomarkers, Tumor - metabolism | Genetic Predisposition to Disease | Risk Factors | Heredity | Carcinoma, Papillary - pathology | Thyroid Cancer, Papillary | Thyroid Neoplasms - genetics | Phenotype | Animals | Sequence Analysis, RNA | Pedigree | Biomarkers, Tumor - genetics | MicroRNAs - genetics | COS Cells | Thyroid Neoplasms - metabolism | Thyroid Neoplasms - pathology
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9. Full Text Clinical Characteristics of Colorectal Cancer Patients with Double Somatic Mismatch Repair Mutations Compared to Lynch Syndrome
by Pearlman, Rachel and Haraldsdottir, Sigurdis and de la Chapelle, Albert and Jonasson, Jon G and Liyanarachchi, Sandya and Frankel, Wendy L and Rafnar, Thorunn and Stefansson, Kari and Pritchard, Colin C and Hampel, Heather
Journal of medical genetics, ISSN 0022-2593, 7/2019, Volume 56, Issue 7, pp. 462 - 470
tumor testing | DNA repair system | Lynch-like syndrome | somatic mutation
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10. Full Text MicroRNAs in Thyroid Cancer
by de la Chapelle, Albert and Jazdzewski, Krystian
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 11/2011, Volume 96, Issue 11, pp. 3326 - 3336
Context: Traditionally, factors predisposing to diseases are either genetic (“nature”) or environmental, also known as lifestyle-related (“nurture”). Papillary... 
MIR-146A GENE | FIRST-DEGREE RELATIVES | HEPATOCELLULAR-CARCINOMA | FUNCTIONAL POLYMORPHISM | HORMONE NUCLEAR RECEPTORS | ENDOCRINOLOGY & METABOLISM | CHRONIC LYMPHOCYTIC-LEUKEMIA | SINGLE NUCLEOTIDE POLYMORPHISM | EXPRESSION PROFILES | PAPILLARY CARCINOMAS | CELL CARCINOMA | Thyroid Neoplasms - genetics | Carcinoma, Papillary - genetics | Genetic Predisposition to Disease | MicroRNAs - genetics | Signal Transduction - genetics | Humans | 100 | 500
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11. Full Text Genetic predisposition to colorectal cancer
by de la Chapelle, Albert
Nature Reviews Cancer, ISSN 1474-175X, 10/2004, Volume 4, Issue 10, pp. 769 - 780
High-penetrance mutations in several genes have been identified that contribute to hereditary colorectal cancer. The role of these mutations in cancer... 
ADENOMATOUS POLYPOSIS-COLI | TUMOR SUSCEPTIBILITY ALLELE | SOMATIC G-C->T-A MUTATIONS | COMMON MSH2 MUTATION | ONCOLOGY | FOUNDER MUTATION | NON-ASHKENAZI JEWS | GERMLINE MUTATIONS | MISMATCH REPAIR | JUVENILE POLYPOSIS | I1307K APC POLYMORPHISM | Colorectal Neoplasms - epidemiology | Genetic Predisposition to Disease | Colorectal Neoplasms - genetics | Colorectal Neoplasms, Hereditary Nonpolyposis - genetics | Humans | Risk Factors | Penetrance | Base Pair Mismatch | DNA Repair - genetics | Organ Specificity | Genes, APC | Neoplastic Syndromes, Hereditary - epidemiology | Colorectal Neoplasms, Hereditary Nonpolyposis - epidemiology | Neoplastic Syndromes, Hereditary - genetics | Mutation | Adenomatous Polyposis Coli - genetics | Genes, DCC | Care and treatment | Usage | Colorectal cancer | Genetic aspects | Diagnosis | Research | Genetic screening | Methods
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12. MYH9 binds to lncRNA gene PTCSC2 and regulates FOXE1 in the 9q22 thyroid cancer risk locus
by Wang, Yanqiang and He, Huiling and Li, Wei and Phay, John and Shen, Rulong and Yu, Lianbo and Hancioglu, Baris and de la Chapelle, Albert
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 01/2017, Volume 114, Issue 3, pp. 474 - 474
A locus on chromosome 9q22 harbors a SNP (rs965513) firmly associated with risk of papillary thyroid carcinoma (PTC). The locus also comprises the forkhead box... 
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13. Full Text Clinical implications of GWAS variants associated with differentiated thyroid cancer
by Jendrzejewski, J and Sworczak, K and Comiskey, DF and de la Chapelle, A
ENDOKRYNOLOGIA POLSKA, ISSN 0423-104X, 2019, Volume 70, Issue 5, pp. 423 - 429
The genetic risk of differentiated thyroid cancer (DTC) probably consists of multiple low-penetrance, single-nucleotide polymorphisms (SNP). Such markers are... 
COMMON VARIANTS | FIRST-DEGREE RELATIVES | GWAS | SUSCEPTIBILITY LOCI | RISK | GENETIC-VARIANTS | RET PROTOONCOGENE | ENDOCRINOLOGY & METABOLISM | genetic predisposition | FACTOR-H POLYMORPHISM | papillary thyroid carcinoma | genome-wide association studies | CARCINOMA | EXPRESSION | PTC | GENOME-WIDE ASSOCIATION
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14. Full Text Clinical Relevance of Microsatellite Instability in Colorectal Cancer
by Albert de la Chapelle and Heather Hampel
Journal of Clinical Oncology, ISSN 0732-183X, 07/2010, Volume 28, Issue 20, pp. 3380 - 3387
Microsatellite instability (MSI) is a clonal change in the number of repeated DNA nucleotide units in microsatellites. It arises in tumors with deficient... 
COLON-CANCER | ADJUVANT CHEMOTHERAPY | BETHESDA GUIDELINES | DNA MISMATCH REPAIR | LYNCH-SYNDROME | ONCOLOGY | HMLH1 PROMOTER HYPERMETHYLATION | YOUNG-PATIENTS | REPLICATION ERRORS | MONONUCLEOTIDE REPEATS | CELL-LINES | Colorectal Neoplasms - therapy | Microsatellite Instability | Prognosis | Colorectal Neoplasms - genetics | DNA Mismatch Repair | Humans | Polymerase Chain Reaction | Genetic Markers | Bon | Biology of Neoplasia | Gic7
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15. Full Text Abstract 301: Identification of NRAS isoform 2 overexpression as a novel mechanism facilitating BRAF inhibitor resistance in malignant melanoma (MM)
by Duggan, Megan and Stiff, Andrew and Olaverria Salavaggione, Gonzalo and Bainazar, Maryam and Latchana, Nicholas and Markowitz, Joseph and de la Chapelle, Albert and Eisfeld, Ann-Kathrin and Carson, William
Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14 Supplement, pp. 301 - 301
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16. Full Text Common SNP in Pre-miR-146a Decreases Mature miR Expression and Predisposes to Papillary Thyroid Carcinoma
by Krystian Jazdzewski and Elizabeth L. Murray and Kaarle Franssila and Barbara Jarzab and Daniel R. Schoenberg and Albert de la Chapelle
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2008, Volume 105, Issue 20, pp. 7269 - 7274
Although papillary thyroid carcinoma (PTC) displays strong heritability, no predisposing germ-line mutations have been found. We show that a common G/C... 
MicroRNA | Thyroid cancer | Papillary carcinoma | RNA | Plasmids | DNA | Genetic mutation | Genotypes | Tumors | Cancer | Genetic predisposition | miR-146 | microRNA processing | Polymorphism | LOCALIZATION | ACTIVATION | MULTIDISCIPLINARY SCIENCES | polymorphism | thyroid cancer | MICRORNAS | GENE | BRAF MUTATIONS | genetic predisposition | HUMAN CANCERS | NF-KAPPA-B | Genetic Predisposition to Disease | Humans | Thyroid Neoplasms - etiology | Genotype | MicroRNAs - biosynthesis | MicroRNAs - metabolism | Carcinoma - etiology | Case-Control Studies | Thyroid Neoplasms - genetics | Transfection | Alleles | Cell Line, Tumor | Carcinoma - genetics | MicroRNAs - genetics | Polymorphism, Single Nucleotide | Mutation | Cohort Studies | Influence | Development and progression | Genetic aspects | Single nucleotide polymorphisms | Research | Gene expression | RNA processing | Identification and classification | Methods | Biological Sciences
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17. Full Text PD-1 Blockade in Tumors with Mismatch-Repair Deficiency
by Le, Dung T and Uram, Jennifer N and Wang, Hao and Bartlett, Bjarne R and Kemberling, Holly and Eyring, Aleksandra D and Skora, Andrew D and Luber, Brandon S and Azad, Nilofer S and Laheru, Dan and Biedrzycki, Barbara and Donehower, Ross C and Zaheer, Atif and Fisher, George A and Crocenzi, Todd S and Lee, James J and Duffy, Steven M and Goldberg, Richard M and de la Chapelle, Albert and Koshiji, Minori and Bhaijee, Feriyl and Huebner, Thomas and Hruban, Ralph H and Wood, Laura D and Cuka, Nathan and Pardoll, Drew M and Papadopoulos, Nickolas and Kinzler, Kenneth W and Zhou, Shibin and Cornish, Toby C and Taube, Janis M and Anders, Robert A and Eshleman, James R and Vogelstein, Bert and Diaz, Luis A
The New England Journal of Medicine, ISSN 0028-4793, 06/2015, Volume 372, Issue 26, pp. 2509 - 2520
Persons with mismatch repair–deficient tumors are more likely than persons with mismatch repair–proficient tumors to benefit from pembrolizumab — which... 
MEDICINE, GENERAL & INTERNAL | COLORECTAL CARCINOMAS | ANTI-PD-L1 ANTIBODY | SAFETY | MICROSATELLITE INSTABILITY | DNA | GERMLINE MUTATIONS | PREDISPOSE | CLINICAL ACTIVITY | CANCER | LYMPHOCYTES | Antibodies, Monoclonal, Humanized - adverse effects | Antibodies, Monoclonal, Humanized - therapeutic use | Colorectal Neoplasms - genetics | Humans | Middle Aged | Kaplan-Meier Estimate | Male | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Antineoplastic Agents - therapeutic use | Adenocarcinoma - drug therapy | Adenocarcinoma - secondary | Disease-Free Survival | Neoplasm Metastasis - genetics | Neoplasm Metastasis - drug therapy | Antineoplastic Agents - adverse effects | Colorectal Neoplasms - drug therapy | DNA Mismatch Repair | Adult | Female | Adenocarcinoma - genetics | Aged | Colorectal Neoplasms - pathology | Antibody diversity | Carcinoma | Genetic disorders | Analysis | Research | Risk factors | Cancer | Tumors | Antigens | Yeast | PD-1 protein | Colorectal carcinoma | Body weight | Colorectal cancer | Autoantigens | DNA repair | Survival | Metastases | Pembrolizumab | Immune checkpoint | Immunogenicity | Mismatch repair | Death | Mutation | Genetic recombination | Cancer therapies | Drug dosages | Immune system | Medical research | Melanoma | Patients | Studies | Hypotheses | Pancreatic cancer | Epigenetics | Biomarkers | Ligands
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