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Cancer Research, ISSN 0008-5472, 08/2015, Volume 75, Issue 15 Supplement, pp. 2324 - 2324
Journal Article
Cancer Research, ISSN 0008-5472, 04/2011, Volume 71, Issue 8 Supplement, pp. 16 - 16
Journal Article
Molecular Cancer, ISSN 1476-4598, 10/2014, Volume 13, Issue 1, p. 230
Background: Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death worldwide. Pemetrexed, a multi-target folate antagonist, has... 
ITF2357 | NSCLC | Givinostat | HDAC inhibitors | Autophagy | Pemetrexed | Synergism | Apoptosis | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOWN-REGULATION | SENSITIVITY | MEDIATED CLEAVAGE | DEATH | PROLIFERATION | THYMIDYLATE SYNTHASE EXPRESSION | MESSENGER-RNA | ONCOLOGY | PROTEASOME | CROSSTALK | MOLECULAR-MECHANISMS | Gene Silencing - drug effects | Apoptosis - drug effects | Guanine - analogs & derivatives | Neoplastic Stem Cells - drug effects | Humans | Lung Neoplasms - pathology | RNA, Messenger - metabolism | Autophagy - drug effects | Neoplastic Stem Cells - metabolism | Guanine - pharmacology | Neoplastic Stem Cells - pathology | Female | Carcinoma, Non-Small-Cell Lung - pathology | Cell Survival - drug effects | Lung Neoplasms - enzymology | RNA, Messenger - genetics | Thymidylate Synthase - metabolism | Down-Regulation - drug effects | Thymidylate Synthase - genetics | Drug Synergism | Xenograft Model Antitumor Assays | Animals | Mice, Nude | Glutamates - pharmacology | Cell Line, Tumor | Histone Deacetylase Inhibitors - pharmacology | Cell Proliferation - drug effects | Carcinoma, Non-Small-Cell Lung - enzymology | Care and treatment | Research | Lung cancer, Non-small cell | Health aspects | Stem cells | Cancer | Medical research | Lung cancer | Oncology | Cytotoxicity | Experiments | Cancer therapies | Patients | DNA repair | Proteins | Cell growth | Chemotherapy | Cell cycle
Journal Article
Nutrition, Metabolism and Cardiovascular Diseases, ISSN 0939-4753, 08/2019, Volume 29, Issue 8, pp. 873 - 874
Journal Article
Scientific Reports, ISSN 2045-2322, 02/2017, Volume 7, Issue 1, pp. 43013 - 43013
Combined MAPK/PI3K pathway inhibition represents an attractive, albeit toxic, therapeutic strategy in oncology. Since PTEN lies at the intersection of these... 
LUNG-CANCER | METASTATIC MELANOMA | SIGNALING PATHWAYS | RAS/RAF/MEK/ERK | MULTIDISCIPLINARY SCIENCES | DEREGULATION | PI3K/PTEN/AKT/MTOR | COMBINATION | NF-KAPPA-B | MAPK PATHWAY | STEM-CELL POPULATION | Neoplastic Stem Cells - cytology | TOR Serine-Threonine Kinases - metabolism | Neoplastic Stem Cells - drug effects | Humans | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | TOR Serine-Threonine Kinases - antagonists & inhibitors | Janus Kinase 1 - metabolism | PTEN Phosphohydrolase - antagonists & inhibitors | Neoplastic Stem Cells - metabolism | RNA Interference | Janus Kinase 1 - genetics | Female | Pyrimidinones - pharmacology | MAP Kinase Kinase Kinases - antagonists & inhibitors | Proto-Oncogene Proteins c-akt - metabolism | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | PTEN Phosphohydrolase - genetics | Everolimus - pharmacology | PTEN Phosphohydrolase - metabolism | MAP Kinase Kinase Kinases - metabolism | Drug Synergism | Animals | Mice, Nude | Cell Line, Tumor | Mice | Protein Kinase Inhibitors - pharmacology | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Pyridones - pharmacology | RNA, Small Interfering - metabolism | TOR protein | Stat3 protein | MAP kinase | Janus kinase | mRNA | Tumor cell lines | PTEN protein | Cancer | 1-Phosphatidylinositol 3-kinase | Index Medicus
Journal Article
eLife, ISSN 2050-084X, 06/2017, Volume 6
Journal Article
Journal of Experimental and Clinical Cancer Research, ISSN 1756-9966, 07/2018, Volume 37, Issue 1, pp. 140 - 14
Journal Article