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Cardiovascular research, ISSN 0008-6363, 08/2019
T-lymphocytes plays an important role in the pathophysiology of acute coronary syndromes (ACS). T-cell activation in vitro by pro-inflammatory cytokines may... 
Journal Article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, ISSN 1422-0067, 10/2019, Volume 20, Issue 19, p. 4931
Manipulation of the immune response is a game changer in lung cancer treatment, revolutionizing management. PD1 and CTLA4 are dynamically expressed on... 
ACTIVATION | nivolumab | BIOCHEMISTRY & MOLECULAR BIOLOGY | Treg | atezolizumab | immune checkpoint inhibitors | CHEMISTRY, MULTIDISCIPLINARY | GUIDELINE | lung cancer | pembrolizumab | durvalumab | immune evasion | IMMUNOTHERAPY | REGULATORY T-CELLS | CLASS-I | ENGAGEMENT | CTLA-4 | tumor microenvironment | MUTATIONS | BLOCKADE | treg
Journal Article
European Journal of Immunology, ISSN 0014-2980, 12/2017, Volume 47, Issue 12, pp. 2039 - 2042
Journal Article
International journal of molecular sciences, ISSN 1422-0067, 05/2019, Volume 20, Issue 9, p. 2258
The therapeutic scenario for elderly patients with advanced NSCLC has been limited to radiotherapy and chemotherapy. Recently, a novel therapeutic approach... 
precision oncology | Elderly patient | Immune checkpoint inhibitors | NSCLC | PD-1/PD-L1 | biological big data
Journal Article
Oncotarget, ISSN 1949-2553, 2017, Volume 8, Issue 40, pp. 68305 - 68316
Regorafenib, an oral multikinase inhibitor, has demonstrated survival benefit in metastatic colorectal cancer (mCRC) patients that have progressed after all... 
Silybin | Regorafenib | Metastatic colorectal cancer (mCRC) | Reactive oxygen species (ROS)
Journal Article
European Journal of Immunology, ISSN 0014-2980, 08/2018, Volume 48, Issue 8, pp. 1266 - 1268
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 03/2017, Volume 128, p. 26
ox-LDL drive O.sup.2- production. O.sup.2- activates the transcription factor NF-[kappa]B that translocates into the nucleus where it activates the... 
Low density lipoproteins | Endothelium | Prevention | Antioxidants | Flavonoids | Flavones | RNA | Bioflavonoids | Analysis | Atherosclerosis | Thrombosis | Blood clot
Journal Article
Clinical and Molecular Allergy, ISSN 1476-7961, 07/2015, Volume 13, Issue 1, p. 12
Crohn's disease (CD) and Hidradenitis suppurativa (HS) are both chronic inflammatory diseases. The pathogenesis of these diseases is multifactorial, due to the... 
Hidradenitis suppurativa | T helper lymphocytes | Crohn's disease | Immune response | Cytokines | T cells | Analysis
Journal Article
Cancer Research, ISSN 0008-5472, 08/2009, Volume 69, Issue 16, pp. 6738 - 6746
Journal Article
New England Journal of Medicine, ISSN 0028-4793, 10/2011, Volume 365, Issue 15, pp. 1451 - 1451
Journal Article
Journal of Vascular Research, ISSN 1018-1172, 12/2010, Volume 48, Issue 1, pp. 59 - 66
Objective: Atherosclerosis is characterized by endothelial inflammation and dysfunction. Adipose tissue has increasingly been recognized as an active endocrine... 
Obesity | Inflammation | Adipokines | Endothelial cells | Tissue factor | C-REACTIVE PROTEIN | PHYSIOLOGY | MACROPHAGES | ATHEROSCLEROSIS | PROMOTES SMOOTH-MUSCLE | MONOCLONAL-ANTIBODY | DISEASE | PERIPHERAL VASCULAR DISEASE | DYSFUNCTION | POTENTIAL ROLE | ADIPOSE-TISSUE
Journal Article
European Journal of Immunology, ISSN 0014-2980, 12/2017, Volume 47, Issue 12, pp. 2039 - 2042
Signaling through the T cell receptor (TCR) regulates T cell homeostasis and effector functions. However, a full accounting of the TCR‐coupled signaling... 
TCR signaling | Phosphoproteome | Immunological synapse | MELC | Treg | ACTIVATION | IMMUNOLOGY | POLARIZATION | Phosphates | Proteins | T cells | Immunoregulation | Immunomodulation | Homeostasis | T cell receptors | Immunological synapses | Lymphocytes T | T-cell receptor | Signaling | Immunology | Lymphocytes | Cytoskeleton
Journal Article
Clinical Science, ISSN 0143-5221, 04/2014, Volume 126, Issue 8, pp. 545 - 556
S1P exerts a diverse set of vascular responses, and PAR-2 has been shown to be involved in vascular inflammation as well as in other inflammatory-based... 
Journal Article
Current Cardiology Reviews, ISSN 1573-403X, 05/2017, Volume 13, Issue 2, pp. 110 - 117
In the last twenty years, our comprehension of the molecular mechanisms involved in the formation, progression and complication of atherosclerotic plaque has... 
Journal Article
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