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Journal of Biological Chemistry, ISSN 0021-9258, 11/2003, Volume 278, Issue 45, pp. 44966 - 44974
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2001, Volume 98, Issue 4, pp. 1387 - 1392
Mutations of the VHL tumor suppressor gene occur in patients with VHL disease and in the majority of sporadic clear cell renal carcinomas (VHL RCC). Loss of... 
Biological Sciences | FACTOR RECEPTOR ANTIBODY | FACTOR-BETA | PROTEIN | MESSENGER-RNA | GENE | UBIQUITIN LIGASE | MULTIDISCIPLINARY SCIENCES | KINASE | IDENTIFICATION | EXPRESSION | CANCER
Journal Article
University of Toronto Faculty of Law Review, ISSN 0381-1638, 03/2005, Volume 63, Issue 2, p. 183
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2003, Volume 278, Issue 45, p. 44966
Bi-allelic-inactivating mutations of the VHL tumor suppressor gene are found in the majority of clear cell renal cell carcinomas (VHL -/- RCC). VHL -/- RCC... 
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 01/2001, Volume 276, Issue 2, p. 1407
Sporadic clear cell renal carcinomas frequently harbor inactivating mutations in exon 2 of the von Hippel-Lindau (VHL) tumor suppressor gene. Here, we examine... 
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 02/2001, Volume 98, Issue 4, p. 1387
  Mutations of the VHL tumor suppressor gene occur in patients with VHL disease and in the majority of sporadic clear cell renal carcinomas (VHL -/- RCC). Loss... 
Kidneys | Genes | Biochemistry | Cells | Tumors | Cancer
Journal Article
Neurology, ISSN 0028-3878, 03/2012, Volume 78, Issue 10, pp. 690 - 695
Objective: Age at onset of diagnostic motor manifestations in Huntington disease (HD) is strongly correlated with an expanded CAG trinucleotide repeat. The... 
HOMOZYGOSITY | ALLELE | OF-ONSET | GENE | LENGTH | MUTATION | CHROMOSOMES | CLINICAL NEUROLOGY | TRINUCLEOTIDE REPEAT | Humans | Age of Onset | Alleles | Huntington Disease - genetics | Adult | Female | Genotype | Huntington Disease - diagnosis | Male | Trinucleotide Repeat Expansion | 164
Journal Article
by Paulsen, Jane S and Long, Jeffrey D and Johnson, Hans J and Aylward, Elizabeth H and Ross, Christopher A and Williams, Janet K and Nance, Martha A and Erwin, Cheryl J and Westervelt, Holly J and Harrington, Deborah L and Bockholt, H. Jeremy and Zhang, Ying and McCusker, Elizabeth A and Chiu, Edmond M and Panegyres, Peter K and Cross, Stephen and Ryan, Patricia and Epping, Eric A and Preston, Joy and Goh, Anita and Antonopoulos, Stephanie and Loi, Samantha and Raymond, Lynn and Decolongon, Joji and Fan, Mannie and Coleman, Allison and Mallone, William M and Suter, Greg and Varvaris, Mark and Yoritomo, Nadine and Griffith, Jane and Loy, Clement and Gunn, David and Guttman, Mark and Sheinberg, Alanna and Law, Albie and Quaid, Kimberly and Wesson, Melissa and Wojcieszek, Joanne and Perlmutter, Joel and Barton, Stacey and Smith, Shineeka and Barker, Roger A and Mason, Sarah and Guzman, Natalie Valle and Perlman, Susan and Clemente, Brian and Jones, Randi and Wood-Siverio, Cathy and Factor, Stewart A and Samii, Ali and Macaraeg, Alma and Lee, Joseph and Tedesco, Maria and Maxwell, Brenton and Kumar, Rajeev and Erickson, Diane and Nickels, Breanna and Marshall, Frederick and Chesire, Amy and Wodarski, Mary and Hickey, Charlyne and Geschwind, Michael D and Sha, Sharon and Satris, Gabriela and Ahmed, Anwar and Reece, Christine and Bura, Alex and Mourany, Lyla and Pillai, Jagan and Mazzoni, Pietro and Marder, Karen and Wasserman, Paula and Craufurd, David and Bek, Judith and Howard, Elizabeth and Warner, Tom and Burrows, Maggie and Orth, Michael and Süßmuth, Sigurd and Barth, Katrin and Trautmann, Sonja and Schwenk, Daniela and Eschenbach, Carolin and Wheelock, Vicki and Kjer, Lisa and Martin, Amanda and Farias, Sarah and Miedzybrodzka, Zosia and Rae, Daniela and D'Alessandro, Mariella and Suchowersky, Oksana and Chua, Phyllis and Komiti, Angela and Rosas, Diana and Rosser, Anne and Price, Kathy and Hunt, Sarah and Jankovic, Joseph and Ondo, William and ... and PREDICT-HD Investigators and PREDICT-HD Investigators and Coordinators of the Huntington Study Group
Frontiers in Aging Neuroscience, ISSN 1663-4365, 2014, Volume 6, p. 78
Journal Article
Human Brain Mapping, ISSN 1065-9471, 10/2015, Volume 36, Issue 10, pp. 3717 - 3732
Huntington disease (HD) is most widely known for its selective degeneration of striatal neurons but there is also growing evidence for white matter (WM)... 
diffusion weighted MRI | prefrontal cortex | cross‐sectional analysis | diffusion tensor imaging | multicenter studies | Huntington's disease | diffusion tractography | Diffusion tractography | Multicenter studies | Diffusion weighted MRI | Prefrontal cortex | Cross-sectional analysis | Diffusion tensor imaging | MRI | RETINAL ISCHEMIA | NEUROSCIENCES | NEUROIMAGING | TEMPORAL-LOBE | cross-sectional analysis | LANGUAGE PATHWAYS | BASAL GANGLIA VOLUME | CORPUS-CALLOSUM | CLINICAL-TRIALS | SPATIAL STATISTICS | DIFFUSION-WEIGHTED IMAGES | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | BRAIN | Predictive Value of Tests | Genetic Predisposition to Disease | Humans | Huntington Disease - pathology | Middle Aged | Huntington Disease - psychology | Probability | Male | Educational Status | Diffusion Tensor Imaging | Prefrontal Cortex - pathology | White Matter - pathology | Neuropsychological Tests | Psychiatric Status Rating Scales | Image Processing, Computer-Assisted | Anisotropy | Cognition Disorders - etiology | Brain Mapping | Huntington Disease - genetics | Repetitive Sequences, Nucleic Acid | Adult | Female | Cognition Disorders - psychology | Neurosciences | Huntington's chorea | Medical genetics | Life Sciences | Bioengineering | Neurons and Cognition | Imaging | Image Processing | Computer Science | Medical Imaging | Engineering Sciences | Signal and Image processing | cross sectional analysis
Journal Article
by Nierman, William C and Pain, Arnab and Anderson, Michael J and Wortman, Jennifer R and Kim, H. Stanley and Arroyo, Javier and Berriman, Matthew and Abe, Keietsu and Archer, David B and Bermejo, Clara and Bennett, Joan and Bowyer, Paul and Chen, Dan and Collins, Matthew and Coulsen, Richard and Davies, Robert and Dyer, Paul S and Farman, Mark and Fedorova, Nadia and Fedorova, Natalie and Feldblyum, Tamara V and Fischer, Reinhard and Fosker, Nigel and Fraser, Audrey and García, Jose L and García, Maria J and Goble, Ariette and Goldman, Gustavo H and Gomi, Katsuya and Griffith-Jones, Sam and Gwilliam, Ryan and Haas, Brian and Haas, Hubertus and Harris, David and Horiuchi, H and Huang, Jiaqi and Humphray, Sean and Jiménez, Javier and Keller, Nancy and Khouri, Hoda and Kitamoto, Katsuhiko and Kobayashi, Tetsuo and Konzack, Sven and Kulkarni, Resham and Kumagai, Toshitaka and Lafton, Anne and Latgé, Jean-Paul and Li, Weixi and Lord, Angela and Lu, Charles and Majoros, William H and May, Gregory S and Miller, Bruce L and Mohamoud, Yasmin and Molina, Maria and Monod, Michel and Mouyna, Isabelle and Mulligan, Stephanie and Murphy, Lee and O'Neil, Susan and Paulsen, Ian and Peñalva, Miguel A and Pertea, Mihaela and Price, Claire and Pritchard, Bethan L and Quail, Michael A and Rabbinowitsch, Ester and Rawlins, Neil and Rajandream, Marie-Adele and Reichard, Utz and Renauld, Hubert and Robson, Geoffrey D and Rodriguez De Cordoba, Santiago and Rodríguez-Peña, Jose M and Ronning, Catherine M and Rutter, Simon and Salzberg, Steven L and Sanchez, Miguel and Sánchez-Ferrero, Juan C and Saunders, David and Seeger, Kathy and Squares, Rob and Squares, Steven and Takeuchi, Michio and Tekaia, Fredj and Turner, Geoffrey and Vazquez De Aldana, Carlos R and Weidman, Janice and White, Owen and Woodward, John and Yu, Jae-Hyuk and Fraser, Claire and Galagan, James E and Asai, Kiyoshi and Machida, Masayuki and Hall, Neil and Barrell, Bart and Denning, David W
Nature, ISSN 0028-0836, 12/2005, Volume 438, Issue 7071, pp. 1151 - 1156
Journal Article
Journal Article