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2004, 1. Aufl., ISBN 9780306478437, [xv], 253
The Genetic Code and the Origin of Life celebrates the 50th anniversary of the discovery of the double helix. This book combines two complementary approaches... 
Genetic code | Evolutionary genetics | Biochemistry, general | Evolution (Biology) | Biochemistry | Evolutionary Biology | Cytology | Cell Biology | Life Sciences
Book
Journal of Biological Chemistry, ISSN 0021-9258, 2018, Volume 293, Issue 49, pp. 19157 - 19158
Since the origin of life, metabolism and protein synthesis have evolved together to balance the vast amounts of ATP and amino acids required for genetic... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSFER-RNA SYNTHETASES | Editors' Picks Highlights
Journal Article
Biomarkers in Medicine, ISSN 1752-0363, 03/2019, Volume 13, Issue 4, pp. 259 - 266
To investigate the presence/absence of the Chr-11 tRNA-Lys-CUU gene as a marker for genetic predisposition to Type 2 diabetes mellitus (T2DM). We enrolled 122... 
T2DM | tRNA gene | tRNA-Lys-CUU | insulin | tRNA | genotypic profiling | gene translation | Type 2 diabetes mellitus | biomarker | PCR
Journal Article
RNA, ISSN 1355-8382, 05/2019, Volume 25, Issue 5, pp. 607 - 619
Adenosine deaminase acting on transfer RNA (ADAT) is an essential eukaryotic enzyme that catalyzes the deamination of adenosine to inosine at the first... 
ADAT | Inosine | TRF | Adenosine | Deaminase | TRNA | inosine | METHYLATION | ADENOSINE-DEAMINASE | tRNA | MITOCHONDRIAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | deaminase | tRF | TRANSLATION | CELLULAR STRESS | adenosine | FRAGMENTS | DATABASE | WOBBLE POSITION | ANTICODON | Anticodons | Enzymes | Deamination | Adenosine deaminase | Ribonucleic acid--RNA | Transfer RNA
Journal Article
Molecular Biology and Evolution, ISSN 0737-4038, 2019, Volume 36, Issue 4, pp. 650 - 662
The modification of adenosine to inosine at the first position of transfer RNA (tRNA) anticodons (I34) is widespread among bacteria and eukaryotes. In... 
Translation | CDS | tRNA | Transcriptome | ADAT | Evolution | mRNA | TadA | Speciation | SILK GLAND | ADENOSINE-DEAMINASE | EF-P | transcriptome | PHYLOGENETIC ANALYSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | STRESS-RESPONSE | evolution | IDENTIFICATION | speciation | EVOLUTIONARY BIOLOGY | SEQUENCE | GENES | GENETICS & HEREDITY | translation | POSTTRANSCRIPTIONAL MODIFICATIONS | ANTICODON
Journal Article
The EMBO Journal, ISSN 0261-4189, 08/2014, Volume 33, Issue 15, pp. 1619 - 1620
The sophistication of the editing mechanisms that prevent gene translation errors indicates that amino acid misincorporation is generally a problem to be... 
QUALITY-CONTROL | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSFER-RNA SYNTHETASES | CELL BIOLOGY | Valine - metabolism | Leucine-tRNA Ligase - metabolism | Leucine-tRNA Ligase - genetics | Valine - analogs & derivatives | Cellular biology | Amino acids | Genetics | Have You Seen?
Journal Article
Cell Reports, ISSN 2211-1247, 04/2019, Volume 27, Issue 1, pp. 40 - 47.e5
The aminoacylation of tRNAs by aminoacyl-tRNA synthetases (ARSs) is a central reaction in biology. Multiple regulatory pathways use the aminoacylation status... 
replication | seryl-tRNA synthetase | tRNA | mtDNA | mitochondria | translation | LON | LON PROTEASE | DEGRADATION | BINDING | DNA | TRANSCRIPTION | CELL BIOLOGY
Journal Article
ChemBioChem, ISSN 1439-4227, 03/2013, Volume 14, Issue 4, pp. 499 - 509
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 04/2019, Volume 116, Issue 17, pp. 8451 - 8456
The human genome encodes hundreds of transfer RNA (tRNA) genes but their individual contribution to the tRNA pool is not fully understood. Deep sequencing of... 
tRNA gene expression | BINDS | PRECURSOR | tRNA fragments | MULTIDISCIPLINARY SCIENCES | piRNA | tRNA sequencing | tissue-specific expression | PIRNAS | CANCER | Brain | Post-transcription | Anticodons | tRNA | Genes | Fragments | Amino acids | Genomes | Quantitation | Gene expression | Tissues | Ribonucleic acid--RNA | Gene sequencing | Bioinformatics | Transfer RNA | Biological Sciences
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Journal Article