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Nature Cell Biology, ISSN 1465-7392, 10/2011, Volume 13, Issue 10, pp. 1272 - 1279
Journal Article
The EMBO Journal, ISSN 0261-4189, 10/2008, Volume 27, Issue 19, pp. 2616 - 2627
Journal Article
The EMBO Journal, ISSN 0261-4189, 01/2015, Volume 34, Issue 2, pp. 200 - 217
Hedgehog signaling is essential for tissue development and stemness, and its deregulation has been observed in many tumors. Aberrant activation of Hedgehog... 
Gli inhibitors | Hedgehog | cancer | Gli1–DNA interaction | Gli1-DNA interaction | Cancer | CANCER-CELLS | STEM-CELLS | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | HUMAN GLIOMA | CELL BIOLOGY | PATHWAY BLOCKADE | INHIBITION | GROWTH | SCORING FUNCTIONS | MEDULLOBLASTOMA | Embryo, Mammalian - drug effects | Embryonic Stem Cells - metabolism | Embryonic Stem Cells - cytology | Receptors, G-Protein-Coupled - metabolism | Isoflavones - pharmacology | Cerebellum - drug effects | Embryo, Mammalian - metabolism | Kruppel-Like Transcription Factors - metabolism | Smoothened Receptor | Female | Glioblastoma - metabolism | Receptors, Cell Surface - physiology | Patched Receptors | DNA - drug effects | Fibroblasts - metabolism | Mutagenesis, Site-Directed | Cerebellum - metabolism | DNA - metabolism | Mice, SCID | Mutation - genetics | Kruppel-Like Transcription Factors - chemistry | Molecular Dynamics Simulation | Mice, Knockout | Animals | Embryonic Stem Cells - drug effects | Signal Transduction - drug effects | Embryo, Mammalian - cytology | Fibroblasts - drug effects | Glioblastoma - pathology | Cerebellum - cytology | Mice, Inbred NOD | Fibroblasts - cytology | Mice | Mice, Inbred BALB C | Zinc Finger Protein GLI1 | Glioblastoma - drug therapy | Kruppel-Like Transcription Factors - genetics | Medical research | Amino acids | Molecular biology | Deoxyribonucleic acid--DNA | Stem cells | Tumors
Journal Article
The EMBO Journal, ISSN 0261-4189, 08/2010, Volume 29, Issue 15, pp. 2646 - 2658
Journal Article
Cell, ISSN 0092-8674, 2004, Volume 119, Issue 4, pp. 529 - 542
During inflammation, NF-κB transcription factors antagonize apoptosis induced by tumor necrosis factor (TNF)α. This antiapoptotic activity of NF-κB involves... 
SIGNAL-TRANSDUCTION | TARGET | OXIDATIVE STRESS | ACTIVATION | HELA-CELLS | JNK | BIOCHEMISTRY & MOLECULAR BIOLOGY | IRON | MICE | SUPEROXIDE-DISMUTASE | CELL-DEATH | CELL BIOLOGY
Journal Article
NATURE CELL BIOLOGY, ISSN 1465-7392, 02/2010, Volume 12, Issue 2, pp. 132 - U91
Hedgehog signalling is crucial for development and is deregulated in several tumours, including medulloblastoma. Regulation of the transcriptional activity of... 
SUPPRESSOR | ACTIVATION | COMPLEX | DOMAIN | TRANSCRIPTION | GENE-EXPRESSION | PROLIFERATION | MICE | MEDULLOBLASTOMA | CANCER | CELL BIOLOGY
Journal Article
Developmental Cell, ISSN 1534-5807, 10/2015, Volume 35, Issue 1, pp. 21 - 35
Developmental Hedgehog signaling controls proliferation of cerebellar granule cell precursors (GCPs), and its aberrant activation is a leading cause of... 
SUPPRESSOR | TARGETING ORNITHINE-DECARBOXYLASE | ACTIVATED PROTEIN-KINASE | PATHWAY | TUMOR | PROLIFERATION | DEVELOPMENTAL BIOLOGY | MUTATIONS | TRANSCRIPTIONAL TARGET | TRANSLATION | REPRESSOR | CELL BIOLOGY | NIH 3T3 Cells | RNA-Binding Proteins - genetics | AMP-Activated Protein Kinases - metabolism | Ornithine Decarboxylase - metabolism | Phosphorylation | Cell Proliferation | Immunoprecipitation | Humans | Hedgehog Proteins - metabolism | Neurons - cytology | Embryo, Mammalian - metabolism | Hedgehog Proteins - genetics | Medulloblastoma - pathology | HEK293 Cells | Female | Neurons - metabolism | Cerebellar Neoplasms - pathology | Medulloblastoma - genetics | Real-Time Polymerase Chain Reaction | Cerebellar Neoplasms - metabolism | Repressor Proteins - metabolism | Fibroblasts - metabolism | Ornithine Decarboxylase - genetics | RNA, Messenger - genetics | Cells, Cultured | Repressor Proteins - genetics | Medulloblastoma - metabolism | Cerebellar Neoplasms - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Polyamines - metabolism | Xenograft Model Antitumor Assays | Animals | Embryo, Mammalian - cytology | Mice, Nude | Fibroblasts - cytology | Mice | AMP-Activated Protein Kinases - genetics | RNA-Binding Proteins - metabolism | Apoptosis | Enzyme inhibitors | Polyamines | Neurons | Medulloblastoma | Physiological aspects | Growth
Journal Article