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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2014, Volume 111, Issue 23, pp. 8428 - 8433
Voltage-gated sodium channels are important targets for the development of pharmaceutical drugs, because mutations in different human sodium channel isoforms... 
Sodium channels | Bromine | Maps | Sodium | Channel blockers | Crystals | Atoms | Binding sites | Crystal structure | Local anesthetics | Pharmacology | QUALITY | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | NA+ CHANNELS | MOLECULAR DETERMINANTS | INHIBITION | LOCAL-ANESTHETICS | LIDOCAINE | pharmacology | DRUGS | crystal structure | STATE-DEPENDENT BLOCK | BINDING | Humans | NAV1.1 Voltage-Gated Sodium Channel - genetics | Bacterial Proteins - chemistry | Molecular Sequence Data | Crystallography, X-Ray | NAV1.1 Voltage-Gated Sodium Channel - metabolism | NAV1.1 Voltage-Gated Sodium Channel - chemistry | Ion Channel Gating - physiology | HEK293 Cells | Sodium Channels - metabolism | Membrane Potentials - drug effects | Protein Structure, Tertiary | Amino Acid Sequence | Triazines - metabolism | Triazines - pharmacology | Alphaproteobacteria - metabolism | Bacterial Proteins - genetics | Models, Molecular | Sodium Channel Blockers - metabolism | Sodium Channel Blockers - pharmacology | Binding Sites - genetics | Membrane Potentials - physiology | Alphaproteobacteria - chemistry | Sequence Homology, Amino Acid | Alphaproteobacteria - genetics | Ion Channel Gating - genetics | Sodium Channels - chemistry | Bacterial Proteins - metabolism | Sodium Channels - genetics | Mutation | Ion Channel Gating - drug effects | Physiological aspects | Prokaryotes | Biological Sciences
Journal Article
Trends in Pharmacological Sciences, ISSN 0165-6147, 10/2019, Volume 40, Issue 10, pp. 718 - 720
Voltage-gated sodium channels (Na s) initiate the action potential waveforms in excitable cells. The molecular mechanisms controlling this process have been... 
membrane protein | resting state | voltage-dependent channel gating | gating charge | sodium channel | voltage-gated ion channel | PHARMACOLOGY & PHARMACY
Journal Article
Biophysical Journal, ISSN 0006-3495, 02/2019, Volume 116, Issue 3, pp. 534a - 534a
Journal Article
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 07/2019, Volume 116, Issue 31, pp. 15540 - 15549
Journal Article