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BIOCHEMISTRY, ISSN 0006-2960, 04/2019, Volume 58, Issue 16, pp. 2176 - 2187
Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are considered noncompetitive inhibitors that structurally alter reverse transcriptase (RT) and... 
HIV-1 RT | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | FLEXIBILITY | RESISTANCE | INTRALYMPHOCYTE FREE MAGNESIUM | DNA-POLYMERASE | HUMAN-IMMUNODEFICIENCY-VIRUS | METAL-IONS | KINETIC CHARACTERIZATION | BINDING
Journal Article
Journal of Bacteriology, ISSN 0021-9193, 04/2018, Volume 200, Issue 7, p. e00579-17
DNA polymerases (DNAPs) recognize 3′ recessed termini on duplex DNA and carry out nucleotide catalysis. Unlike promoter-specific RNA polymerases (RNAPs), no... 
Binding | Enrichment | DNA polymerase | Nucleotide sequence | Phages | Biological evolution | Nucleotides | Ribonucleic acid--RNA | Polymerase | Thermodynamics | Exonuclease | Primers | Ligands | Evolution | Affinity | Catalysis | Deoxyribonucleic acid--DNA | DNA-directed DNA polymerase | Information theory
Journal Article
ACS CHEMICAL BIOLOGY, ISSN 1554-8929, 10/2019, Volume 14, Issue 10, pp. 2166 - 2175
Systematic Evolution of Ligands by Exponential Enrichment (SELEX) is the iterative process by which nucleic acids that can bind with high affinity and... 
DNA APTAMERS | RNA LIGANDS | EVOLUTION | INHIBITION | QUADRUPLEX | BIOCHEMISTRY & MOLECULAR BIOLOGY | REVERSE-TRANSCRIPTASE | IN-VITRO SELECTION | 2'F-ANA | IDENTIFICATION | CONFORMATIONS
Journal Article
Protein Science, ISSN 0961-8368, 01/2016, Volume 25, Issue 1, pp. 46 - 55
Journal Article
ACS Chemical Biology, ISSN 1554-8929, 11/2016, Volume 11, Issue 11, pp. 3226 - 3226
Journal Article
Bio-protocol, ISSN 2331-8325, 06/2015, Volume 5, Issue 12
Steady state kinetic assays have been a reliable way to estimate fidelity of several polymerases (Menendez-Arias, 2009; Rezende and Prasad, 2004; Svarovskaia ,... 
Journal Article
AIDS Research and Human Retroviruses, ISSN 0889-2229, 10/2018, Volume 34, Issue S1, pp. 1 - 407
Journal Article
Biochemistry, ISSN 0006-2960, 01/2017, Volume 56, Issue 1, pp. 33 - 46
Reverse transcriptases (RTs) are typically assayed in vitro with 5–10 mM Mg2+, whereas the free Mg2+ concentration in cells is much lower. Artificially high... 
DEPENDENT DNA-POLYMERASE | ANGSTROM RESOLUTION | MECHANISM | ACTIVE-SITE | RNASE-H ACTIVITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | SELECTIVE EXCISION | DRUG-RESISTANCE | 4'-ETHYNYL-2-FLUORO-2'-DEOXYADENOSINE EFDA | HUMAN-IMMUNODEFICIENCY-VIRUS | TYPE-1
Journal Article
Virus Research, ISSN 0168-1702, 01/2010, Volume 147, Issue 1, p. 53
The fidelity of poliovirus RNA-dependent RNA polymerase (3Dpol) was determined using a modified [alpha]-complementation assay. Several polymerases have been... 
Cell research | Reverse transcriptase | Phosphatases | Synthesis | Molecular genetics | Peptides | RNA | Glutathione transferase | Analysis | Leukemia | Genetic aspects
Journal Article
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