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1. Full Text EC‐01‐01: BRAIN STATE AND CLEARANCE FROM THE PARENCHYMA
by Deane, Rashid
Alzheimer's & dementia, ISSN 1552-5260, 07/2018, Volume 14, Issue 7S_Part_3, pp. P210 - P211
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2. Full Text Relationship Between CSF and Brain in Protein Clearance and Dementia
by Deane, Rashid
Alzheimer's & dementia, ISSN 1552-5260, 07/2017, Volume 13, Issue 7, pp. P180 - P180
Brain | Dementia
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3. Full Text Impairment of paravascular clearance pathways in the aging brain
by Kress, Benjamin T and Iliff, Jeffrey J and Xia, Maosheng and Wang, Minghuan and Wei, Helen S and Zeppenfeld, Douglas and Xie, Lulu and Kang, Hongyi and Xu, Qiwu and Liew, Jason A and Plog, Benjamin A and Ding, Fengfei and Deane, Rashid and Nedergaard, Maiken
Annals of neurology, ISSN 0364-5134, 12/2014, Volume 76, Issue 6, pp. 845 - 861
Neurosciences | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Cerebrovascular Circulation - physiology | Neuroglia - pathology | Mice, Inbred C57BL | Male | Metabolic Clearance Rate - physiology | Aging - pathology | Brain - metabolism | Animals | Aquaporin 4 - metabolism | Brain - pathology | Female | Microscopy, Fluorescence, Multiphoton - methods | Neuroglia - metabolism | Mice | Aging - metabolism | Medical research | Rodents | Index Medicus
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4. Full Text Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging
by Bell, Robert D and Winkler, Ethan A and Sagare, Abhay P and Singh, Itender and LaRue, Barb and Deane, Rashid and Zlokovic, Berislav V
Neuron (Cambridge, Mass.), ISSN 0896-6273, 2010, Volume 68, Issue 3, pp. 409 - 427
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Immunohistochemistry | Inflammation - chemically induced | Inflammation - pathology | Cerebrovascular Circulation - physiology | Electrophysiology | Brain - growth & development | Pericytes - physiology | Receptor, Platelet-Derived Growth Factor beta - genetics | Brain - physiology | Capillaries - physiology | Microcirculation - physiology | Neurons - physiology | Blood-Brain Barrier - physiology | Microscopy, Fluorescence, Multiphoton | In Situ Nick-End Labeling | Laser-Doppler Flowmetry | Blotting, Western | Mice, Knockout | Autoradiography | Microscopy, Confocal | Phenotype | Animals | Aging - physiology | Fluorescent Antibody Technique | Mice | Brain | Brain damage | Genetic aspects | Neurons | Blood proteins | Diabetic retinopathy | Gene expression | Experiments | Variance analysis | Proteins | Studies | Genotype & phenotype | Cell growth | Rodents | Lectins | Behavior | Diabetes | Age | Apoptosis | Index Medicus | Aging
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5. Full Text Sleep Drives Metabolite Clearance from the Adult Brain
by Lulu Xie and Hongyi Kang and Qiwu Xu and Michael J. Chen and Yonghong Liao and Meenakshisundaram Thiyagarajan and John O'Donnell and Daniel J. Christensen and Charles Nicholson and Jeffrey J. Iliff and Takahiro Takano and Rashid Deane and Maiken Nedergaard
Science (American Association for the Advancement of Science), ISSN 0036-8075, 10/2013, Volume 342, Issue 6156, pp. 373 - 377
Brain | Sleep | Volume | REPORTS | Tracer bullets | Adrenergics | Anesthesia | Mice | Cerebrospinal fluid | Cisterna magna | T tests | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Vertebrates: nervous system and sense organs | Biological and medical sciences | Sleep. Vigilance | Receptors, Adrenergic - metabolism | Mice, Inbred C57BL | Adrenergic Antagonists - administration & dosage | Male | Electroencephalography | Extracellular Space | Neurodegenerative Diseases - metabolism | Intracellular Space | Quaternary Ammonium Compounds - chemistry | Brain - physiology | Cerebral Cortex - metabolism | Brain - metabolism | Animals | Cerebrospinal Fluid - metabolism | Amyloid beta-Peptides - metabolism | Wakefulness - physiology | Cerebral Cortex - physiology | Sleep - physiology | Diffusion | Physiological aspects | Central nervous system | Neurosciences | Metabolites | Insomnia | Sleep deprivation | Index Medicus | State of the art | Consolidation | Metabolic wastes | Arousal | Adults
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6. Role of the blood-brain barrier in the pathogenesis of Alzheimer's disease
by Deane, Rashid and Zlokovic, Berislav V
Current Alzheimer research, ISSN 1567-2050, 04/2007, Volume 4, Issue 2, pp. 191 - 197
sLRP | BBB | LRP1 | Aging | Cerebrovascular | Amyloid-β | RAGE | Animals | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Alzheimer Disease - metabolism | Amyloid beta-Peptides - metabolism | Blood-Brain Barrier - physiopathology | Low Density Lipoprotein Receptor-Related Protein-1 - metabolism | Biological Transport - physiology | Receptor for Advanced Glycation End Products | Receptors, Immunologic - metabolism | Alzheimer Disease - pathology | Index Medicus
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7. Full Text Direct neuronal glucose uptake heralds activity-dependent increases in cerebral metabolism
by Lundgaard, Iben and Li, Baoman and Xie, Lulu and Kang, Hongyi and Sanggaard, Simon and Haswell, John D. R and Sun, Wei and Goldman, Siri and Blekot, Solomiya and Nielsen, Michael and Takano, Takahiro and Deane, Rashid and Nedergaard, Maiken
Nature communications, ISSN 2041-1723, 04/2015, Volume 6, Issue 1, pp. 6807 - 6807
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Immunohistochemistry | Anesthetics, Dissociative - pharmacology | Humans | Functional Neuroimaging - methods | RNA, Messenger - metabolism | Cerebral Cortex - metabolism | Deoxyglucose | Brain - metabolism | Spectroscopy, Near-Infrared | Wakefulness | Xylazine - pharmacology | Neurons - metabolism | Cerebral Cortex - drug effects | Hexokinase - genetics | Neurons - drug effects | Physical Stimulation | Astrocytes - drug effects | Cells, Cultured | Reverse Transcriptase Polymerase Chain Reaction | Antimetabolites | Brain - drug effects | Animals | Glucose - metabolism | Hypnotics and Sedatives - pharmacology | Mice | Hexokinase - metabolism | Ketamine - pharmacology | Astrocytes - metabolism | Index Medicus | Basic Medicine | Neurologi | Clinical Medicine | Neurology | Neurosciences | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Klinisk medicin | Neurovetenskaper
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8. Full Text Suppression of glymphatic fluid transport in a mouse model of Alzheimer's disease
by Peng, Weiguo and Achariyar, Thiyagarajan M and Li, Baoman and Liao, Yonghong and Mestre, Humberto and Hitomi, Emi and Regan, Sean and Kasper, Tristan and Peng, Sisi and Ding, Fengfei and Benveniste, Helene and Nedergaard, Maiken and Deane, Rashid
Neurobiology of disease, ISSN 0969-9961, 2015, Volume 93, pp. 215 - 225
Neurology | Lymphatic system | Astrocytes | CSF | Brain ISF clearance | AQP4 | Convective ISF flow | Clearance | Amyloid-β | Alzheimer's disease | Glymphatic pathways | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Brain - metabolism | Animals | Mice, Inbred C57BL | Alzheimer Disease - metabolism | Amyloid beta-Peptides - metabolism | Plaque, Amyloid - metabolism | Biological Transport - physiology | Neurons - metabolism | Disease Progression | Disease Models, Animal | Oligomers | Analysis | Target marketing | Index Medicus | Alzheimer’s disease | amyloid-β | clearance | brain ISF clearance | astrocytes | lymphatic system
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9. Full Text RAGE (Yin) versus LRP (Yang) balance regulates Alzheimer amyloid β-peptide clearance through transport across the blood-brain barrier
by Deane, Rashid and Wu, Zhenhua and Zlokovic, Berislav V
Stroke (1970), ISSN 0039-2499, 11/2004, Volume 35, Issue 11, pp. 2628 - 2631
Blood-brain barrier | Amyloid β-protein | Alzheimer disease | Acute care | Animals | Central Nervous System - metabolism | Humans | Alzheimer Disease - metabolism | Amyloid beta-Peptides - metabolism | Homeostasis | Cerebral Amyloid Angiopathy, Familial - metabolism | Cerebrovascular Circulation | LDL-Receptor Related Protein-Associated Protein - metabolism | Receptor for Advanced Glycation End Products | Receptors, Immunologic - metabolism | Blood-Brain Barrier - metabolism | Index Medicus
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10. Full Text Apolipoprotein e controls cerebrovascular integrity via cyclophilin A
by Bell, Robert D and Winkler, Ethan A and Singh, Itender and Sagare, Abhay P and Deane, Rashid and Wu, Zhenhua and Holtzman, David M and Betsholtz, Christer and Armulik, Annika and Sallstrom, Jan and Berk, Bradford C and Zlokovic, Berislav V
Nature (London), ISSN 0028-0836, 05/2012, Volume 485, Issue 7399, pp. 512 - 516
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Neurology | Organic mental disorders. Neuropsychology | Psychology. Psychoanalysis. Psychiatry | Adult and adolescent clinical studies | Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases | Psychopathology. Psychiatry | Biological and medical sciences | Medical sciences | Neurons - pathology | Apolipoprotein E4 - genetics | Apolipoproteins E - deficiency | Cerebrovascular Circulation - physiology | Humans | Blood-Brain Barrier - physiopathology | NF-kappa B - metabolism | Apolipoproteins E - metabolism | Microcirculation | Matrix Metalloproteinase 9 - metabolism | Apolipoprotein E2 - deficiency | Apolipoprotein E4 - deficiency | Apolipoprotein E3 - deficiency | Blood-Brain Barrier - physiology | Neurons - metabolism | Cyclophilin A - metabolism | Apolipoprotein E4 - metabolism | Neurodegenerative Diseases - pathology | Apolipoprotein E2 - genetics | Pericytes - metabolism | Mice, Transgenic | Hippocampus - pathology | Neurodegenerative Diseases - metabolism | Apolipoprotein E3 - metabolism | Apolipoprotein E2 - metabolism | Blood-Brain Barrier - drug effects | Cyclophilin A - antagonists & inhibitors | Hippocampus - metabolism | Apolipoprotein E3 - genetics | Animals | Apolipoproteins E - genetics | Mice | Cyclophilin A - deficiency | Cyclophilin | Brain cells | Physiological aspects | Development and progression | Apolipoproteins | Properties | Alzheimer's disease | Proteins | Studies | Rodents | Index Medicus | Medicin och hälsovetenskap
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11. Full Text Biomarkers of traumatic injury are transported from brain to blood via the glymphatic system
by Plog, Benjamin A and Dashnaw, Matthew L and Hitomi, Emi and Peng, Weiguo and Liao, Yonghong and Lou, Nanhong and Deane, Rashid and Nedergaard, Maiken
The Journal of neuroscience, ISSN 0270-6474, 01/2015, Volume 35, Issue 2, pp. 518 - 526
Lymphatic | Biomarker | Traumatic brain injury | Clearance | CSF | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Mice, Inbred C57BL | Metabolic Clearance Rate | Biomarkers - blood | Brain Injuries - metabolism | Sleep Deprivation - metabolism | Blood-Brain Barrier - metabolism | S100 Calcium Binding Protein beta Subunit - blood | Glial Fibrillary Acidic Protein - cerebrospinal fluid | Glial Fibrillary Acidic Protein - blood | Extracellular Fluid - metabolism | Sleep Deprivation - cerebrospinal fluid | Animals | Brain Injuries - cerebrospinal fluid | Brain Injuries - blood | Female | Neuroglia - metabolism | Mice | Biomarkers - cerebrospinal fluid | S100 Calcium Binding Protein beta Subunit - cerebrospinal fluid | Sleep Deprivation - blood | Index Medicus | traumatic brain injury | clearance | biomarker | lymphatic
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