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Lancet, The, ISSN 0140-6736, 2012, Volume 379, Issue 9823, pp. 1301 - 1309
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2015, Volume 10, Issue 6, p. e0131670
Glioblastoma multiforme (GBM) is the most common primary brain tumor and among the most difficult to treat malignancies per se. In almost 90% of all GBM... 
MALIGNANT GLIOMA | GLIOMA-CELL LINES | APOPTOSIS | PROTEIN | 3-KINASE | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | DUAL INHIBITOR | DIFFERENTIATION | CANCER | TEMOZOLOMIDE | TOR Serine-Threonine Kinases - metabolism | Apoptosis - drug effects | Furans - pharmacology | Humans | Brain Neoplasms - pathology | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Brain Neoplasms - metabolism | TOR Serine-Threonine Kinases - antagonists & inhibitors | Dacarbazine - pharmacology | Dacarbazine - analogs & derivatives | Glioblastoma - metabolism | Antineoplastic Agents - pharmacology | Cell Survival - drug effects | Pyrimidines - pharmacology | Brain Neoplasms - drug therapy | Drug Synergism | Cell Movement - drug effects | Signal Transduction - drug effects | Glioblastoma - pathology | Cell Line, Tumor | Cell Proliferation - drug effects | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | Glioblastoma - drug therapy | Neoplasm Staging | Chemotherapy | Health aspects | Glioblastoma multiforme | Analysis | Apoptosis | Cancer | TOR protein | Cell proliferation | Brain | Pediatrics | Cell culture | Biotechnology | Brain tumors | Brain cancer | Glioblastoma | AKT protein | Neurosurgery | Neuroblastoma | Kinases | Cancer therapies | Proteins | Penicillin | Cell cycle | Therapeutic applications | Data processing | Pharmacology | Seniority | Gene expression | 1-Phosphatidylinositol 3-kinase | Medicine | Signaling | Inhibitors | Cell lines | Stem cells
Journal Article
Journal Article
International Journal of Oncology, ISSN 1019-6439, 11/2018, Volume 53, Issue 5, pp. 1881 - 1896
Journal Article
Blood, ISSN 0006-4971, 11/2011, Volume 118, Issue 21, pp. 2572 - 2572
Abstract Abstract 2572 Treatment of acute lymphoblastic leukemia (ALL), the most frequent malignant disease in children and adolescents, is increasingly... 
Journal Article
Blood, ISSN 0006-4971, 11/2012, Volume 120, Issue 21, pp. 2518 - 2518
Abstract Abstract 2518 B cell precursor acute lymphoblastic leukemia (BCP-ALL) is a heterogeneous disease and frequently associated with genetic alterations.... 
Journal Article
Experimental Hematology, ISSN 0301-472X, 2014, Volume 42, Issue 2, pp. 90 - 100
KIT inhibition with dasatinib represents a promising approach to targeted therapy in t(8;21) acute myeloid leukemia (AML) and clinical trials are currently... 
Hematology, Oncology and Palliative Medicine | Advanced Basic Science | TARGETED THERAPY | MEDICINE, RESEARCH & EXPERIMENTAL | WILD-TYPE | ACTIVATION | GROWTH | ACQUIRED-RESISTANCE | C-KIT | KINASE INHIBITORS | MECHANISMS | MUTATIONS | HEMATOLOGY | CANCER-THERAPY
Journal Article
Oncogenesis, ISSN 2157-9024, 11/2017, Volume 6, Issue 11, pp. 4 - 9
The PI3K/Akt/mTOR signalling network is activated in almost 90% of all glioblastoma, the most common primary brain tumour, which is almost invariably lethal... 
MALIGNANT GLIOMA | APOPTOSIS | INVASION | PATTERN | ONCOLOGY | GENE-EXPRESSION | AUTOPHAGY | CANCER | GDC-0941 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | TEMOZOLOMIDE | TOR protein | Motility | Cell survival | Brain tumors | Brain cancer | Glioblastoma | AKT protein | Rapamycin | Population genetics | 1-Phosphatidylinositol 3-kinase | Signal transduction | Stem cells | Survival factor | Temozolomide | Apoptosis
Journal Article
BIOMEDICINES, ISSN 2227-9059, 09/2019, Volume 7, Issue 3, p. 69
Journal Article
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 08/2019, Volume 144, Issue 2, pp. 574 - 583.e5
Journal Article