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1. Full Text 4L Lymph Node Involvement in Left-Sided Lung Cancer: Unique or Not?
by De Ruysscher, Dirk K M and Decaluwé, Herbert
Journal of Clinical Oncology, ISSN 0732-183X, 10/2018, Volume 36, Issue 29, pp. 2907 - 2908
SURGERY | LYMPHADENECTOMY | RESECTION | POSTOPERATIVE RADIOTHERAPY | PATTERNS | TARGET VOLUME | CHEMOTHERAPY | ONCOLOGY | Lymph Node Excision | Lung Neoplasms - surgery | Lymph Nodes | Humans
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2. Full Text RNA-sequencing in non-small cell lung cancer shows gene downregulation of therapeutic targets in tumor tissue compared to non-malignant lung tissue
by Reynders, Kobe and Wauters, Els and Moisse, Matthieu and Decaluwe, Herbert and De Leyn, Paul and Peeters, Stephanie and Lambrecht, Maarten and Nackaerts, Kristiaan and Dooms, Christophe and Janssens, Wim and Vansteenkiste, Johan and Lambrechts, Diether and De Ruysscher, Dirk
Radiation Oncology, ISSN 1748-717X, 07/2018, Volume 13, Issue 1, pp. 131 - 8
Background: Gene expression of specific therapeutic targets in non-malignant lung tissue might play an important role in optimizing targeted therapies. This... 
Targeted treatment | METAANALYSIS | NSCLC | DNA METHYLATION | DOCETAXEL | SIGNATURE | CHEMOTHERAPY | RNA-sequencing | PD-L1 | GROWTH-FACTOR | INHIBITORS | NIVOLUMAB | CARCINOMA | DIAGNOSTICS | ONCOLOGY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | RNA sequencing | Usage | Physiological aspects | Genetic aspects | Research | Lung cancer, Non-small cell | Drug therapy | Genetic regulation | C-reactive protein | Genes | Lung cancer | Kinases | Cancer therapies | Optimization | Gene sequencing | Proteins | Smoking cessation | Surgery | DNA methylation | Chronic obstructive pulmonary disease | Vascular endothelial growth factor | Bioinformatics | Therapeutic applications | Lung diseases | Non-small cell lung carcinoma | Data processing | Histology | Gene expression | Ribonucleic acid--RNA | Patients | Vascular endothelial growth factor receptors | Chemotherapy | PD-L1 protein | Obstructive lung disease | Stem cells | Biomarkers | Ligands | Methylation | Tumors | Smoking | Cancer | Apoptosis
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3. Full Text One, two, three or four ports... does it matter? Priorities in lung cancer surgery
by Decaluwé, Herbert
Journal of Thoracic Disease, ISSN 2072-1439, 2016, Volume 8, Issue 12, pp. E1704 - E1708
VISUAL ANALOG SCALE | SURVIVAL | PAIN | LYMPHADENECTOMY | RESPIRATORY SYSTEM | ASSISTED THORACOSCOPIC LOBECTOMY | PATTERNS | RADIOTHERAPY | THORACIC-SURGERY | CLINICAL-SIGNIFICANCE | RESECTIONS
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4. Full Text Endosonography for mediastinal nodal staging of clinical N1 non-small cell lung cancer: a prospective multicenter study
by Dooms, C and Tournoy, K.G and Schuurbiers, O and Decaluwe, H and Ryck, F. De and Verhagen, A and Beelen, R and Heijden, E. van der and Leyn, P. De
Chest, ISSN 0012-3692, 2015, Volume 147, Issue 1, pp. 209 - 215
BACKGROUND: Patients with clinical N1 (cN1) lung cancer based on imaging are at risk for malignant mediastinal nodal involvement (N2 disease). Endosonography... 
DIAGNOSIS | MANAGEMENT | ESTS GUIDELINES | RESPIRATORY SYSTEM | CRITICAL CARE MEDICINE | Predictive Value of Tests | Ultrasonography, Interventional - methods | Reproducibility of Results | Lymph Nodes - pathology | Prognosis | Mediastinum | Humans | Lung Neoplasms - pathology | Male | Carcinoma, Non-Small-Cell Lung - diagnosis | Lymphatic Metastasis | Mediastinoscopy - methods | Neoplasm Staging - methods | Carcinoma, Non-Small-Cell Lung - secondary | Biopsy | Female | Lung Neoplasms - diagnostic imaging | Aged | Lymph Nodes - diagnostic imaging | Usage | Endoscopic ultrasonography | Mediastinal tumors | Diagnosis | Mediastinoscopy | Lung cancer, Non-small cell | Risk factors
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5. Full Text DNA methylation profiling of non-small cell lung cancer reveals a COPD-driven immune-related signature
by Wauters, Els and Janssens, Wim and Vansteenkiste, Johan and Decaluwé, Herbert and Heulens, Nele and Thienpont, Bernard and Zhao, Hui and Smeets, Dominiek and Sagaert, Xavier and Coolen, Johan and Decramer, Marc and Liston, Adrian and De Leyn, Paul and Moisse, Matthieu and Lambrechts, Diether
Thorax, ISSN 0040-6376, 12/2015, Volume 70, Issue 12, pp. 1113 - 1122
IntroductionNon-small cell lung cancer (NSCLC) is a heterogeneous disorder consisting of distinct molecular subtypes each characterised by specific genetic and... 
PATHWAYS | DIAGNOSIS | OBSTRUCTIVE PULMONARY-DISEASE | PROJECT | RESPIRATORY SYSTEM | SMOKING HISTORY | EMPHYSEMA | REGULATORY T-CELLS | GENE-EXPRESSION | IMMUNOLOGY | HEALTH | Carcinoma, Non-Small-Cell Lung - immunology | DNA Methylation - immunology | Lung Neoplasms - immunology | Lung Neoplasms - epidemiology | Comorbidity | Humans | Carcinoma, Non-Small-Cell Lung - epidemiology | Pulmonary Disease, Chronic Obstructive - immunology | Pulmonary Disease, Chronic Obstructive - epidemiology | Care and treatment | Diagnosis | Research | Lung cancer, Non-small cell | Gene expression | Health aspects | Smoking | Lung cancer | Values | Genomes | Cancer therapies | Cell adhesion & migration | Studies | Surgery | Immunotherapy | DNA methylation | Epigenetics | Age | Deoxyribonucleic acid--DNA | Immune system | Tumors
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6. Full Text Phenotype molding of stromal cells in the lung tumor microenvironment
by Lambrechts, Diether and Wauters, Els and Boeckx, Bram and Aibar, Sara and Nittner, David and Burton, Oliver and Bassez, Ayse and Decaluwé, Herbert and Pircher, Andreas and Van den Eynde, Kathleen and Weynand, Birgit and Verbeken, Erik and De Leyn, Paul and Liston, Adrian and Vansteenkiste, Johan and Carmeliet, Peter and Aerts, Stein and Thienpont, Bernard
Nature Medicine, ISSN 1078-8956, 08/2018, Volume 24, Issue 8, pp. 1277 - 1289
Cancer cells are embedded in the tumor microenvironment (TME), a complex ecosystem of stromal cells. Here, we present a 52,698-cell catalog of the TME... 
MEDICINE, RESEARCH & EXPERIMENTAL | ANGIOGENESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | C-MYC | RANDOMIZED CONTROLLED-TRIAL | CANCER | VESSEL NORMALIZATION | CELL BIOLOGY | HETEROGENEITY | RNA-SEQ | GENE-EXPRESSION | TRANSCRIPTION FACTOR | REVEALS | Immunohistochemistry | RNA sequencing | Usage | Lung cancer | Cancer cells | Genetic aspects | Research | Diagnosis | Genetic transcription | Subpopulations | Phenotypes | Transcription factors | Cell survival | Genes | Lymphocytes T | Ribonucleic acid--RNA | Gene expression | Endothelial cells | Gene sequencing | Homing | Heterogeneity | Immune checkpoint | Stromal cells | Collagen | Fibroblasts | Cell migration | Immune system | Cancer | Tumors
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7. Full Text Spontaneous Hemothorax, A Rare Face of Vertebral Osteochondroma
by Sainte, Sarah, MD and Decaluwé, Herbert, MD and Vanbrabant, Peter, MD
Journal of Emergency Medicine, ISSN 0736-4679, 2017, Volume 52, Issue 6, pp. e225 - e228
Abstract Background Osteochondroma is the most common benign tumor of the bone. It is usually asymptomatic, but complications may result from mechanical injury... 
Emergency | vertebral exostosis | diaphragmatic injury | osteochondroma | spontaneous hemothorax | EMERGENCY MEDICINE | COSTAL | MULTIPLE EXOSTOSES | Rupture, Spontaneous - physiopathology | Osteochondroma - diagnosis | Humans | Tomography, X-Ray Computed - methods | Hemothorax - physiopathology | Rupture, Spontaneous - diagnosis | Neoplasm Recurrence, Local - pathology | Osteochondroma - physiopathology | Chest Pain - physiopathology | Chest Pain - etiology | Radiography - methods | Emergency Service, Hospital - organization & administration | Adult | Female | Hemothorax - etiology | Osteochondroma - complications | Emergency medicine
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8. Full Text Minimally invasive esophagectomy for cancer
by Decker, Georges and Coosemans, Willy and De Leyn, Paul and Decaluwé, Herbert and Nafteux, Philippe and Van Raemdonck, Dirk and Lerut, Toni
European Journal of Cardio-Thoracic Surgery, ISSN 1010-7940, 1/2009, Volume 35, Issue 1, pp. 13 - 21
Summary Since 1992, various combinations of thoracoscopy (VATS), laparoscopy or hand-assisted thoracolaparoscopy have been used for 'minimally invasive' cancer... 
Laparoscopy | Surgery | Thoracoscopy | Cancer | Esophagus | CARDIAC & CARDIOVASCULAR SYSTEMS | GASTROESOPHAGEAL JUNCTION | THORACIC ESOPHAGUS | THORACOSCOPIC ESOPHAGECTOMY | INITIAL-EXPERIENCE | ASSISTED ENDOSCOPIC ESOPHAGECTOMY | BARRETTS-ESOPHAGUS | LAPAROSCOPIC TRANSHIATAL ESOPHAGECTOMY | DISTAL ESOPHAGUS | HOSPITAL VOLUME | RESPIRATORY SYSTEM | MEDIASTINAL LYMPHADENECTOMY | Minimally Invasive Surgical Procedures - methods | Esophageal Neoplasms - surgery | Humans | Treatment Outcome | Esophagectomy - methods | Neoplasm Staging | Thoracic Surgery, Video-Assisted - methods | Esophageal Neoplasms - pathology | Research | Health aspects | Oncology, Experimental | Analysis
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9. Full Text Patterns of Locoregional Relapses in Patients with Contemporarily Staged Stage III-N2 NSCLC Treated with Induction Chemotherapy and Resection: Implications for Postoperative Radiotherapy Target Volumes
by Billiet, Charlotte and De Ruysscher, Dirk and Peeters, Stéphanie and Decaluwé, Herbert and Vansteenkiste, Johan and Dooms, Christophe and Deroose, Christophe M and De Leyn, Paul and Hendrikx, Marc and Bulens, Paul and Le Péchoux, Cécile and Mebis, Jeroen
Journal of Thoracic Oncology, ISSN 1556-0864, 09/2016, Volume 11, Issue 9, pp. 1538 - 1549
Our aim was to evaluate locoregional relapse (LR) patterns after induction chemotherapy and surgery for stage III-N2 NSCLC staged with current standard methods... 
Postoperative radiotherapy | Stage III | NSCLC | Target volume | Local recurrence | ADJUVANT CHEMOTHERAPY | SURVIVAL | TOMOGRAPHY | PHASE-III | ESTS GUIDELINES | FAILURE | RADIATION-THERAPY | CELL LUNG-CANCER | ONCOLOGY | RESPIRATORY SYSTEM | RECURRENCE | CONCURRENT | Carcinoma, Non-Small-Cell Lung - pathology | Prospective Studies | Lung Neoplasms - mortality | Humans | Middle Aged | Neoplasm Recurrence, Local | Induction Chemotherapy | Lung Neoplasms - pathology | Male | Combined Modality Therapy | Lung Neoplasms - therapy | Pneumonectomy | Tumor Burden | Carcinoma, Non-Small-Cell Lung - mortality | Positron Emission Tomography Computed Tomography | Carcinoma, Non-Small-Cell Lung - therapy | Aged, 80 and over | Adult | Female | Lung Neoplasms - diagnostic imaging | Aged | Carcinoma, Non-Small-Cell Lung - diagnostic imaging | Neoplasm Staging
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10. Full Text Postoperative Radiotherapy for Lung Cancer: Is it worth the controversy?
by Billiet, Charlotte and Peeters, Stéphanie and Decaluwé, Herbert and Vansteenkiste, Johan and Mebis, Jeroen and Ruysscher, Dirk De
Cancer Treatment Reviews, ISSN 0305-7372, 2016, Volume 51, pp. 10 - 18
Abstract Introduction The role of postoperative radiation therapy (PORT) in patients with completely resected non-small cell lung cancer (NSCLC) with... 
Hematology, Oncology and Palliative Medicine | Non-small-cell lung cancer | Post-operative radiotherapy | Review | ADJUVANT CHEMOTHERAPY | SURVIVAL | INDUCTION CHEMOTHERAPY | MICROSCOPIC RESIDUAL DISEASE | PHASE-III | RADIATION-THERAPY | STAGE-II | INTERCURRENT DISEASE | HODGKINS-DISEASE | ONCOLOGY | SURGICAL RESECTION | Meta-Analysis as Topic | Humans | Lung Neoplasms - radiotherapy | Lung Neoplasms - surgery | Postoperative Care - methods | Radiotherapy, Adjuvant | Randomized Controlled Trials as Topic | Lung cancer, Non-small cell | Radiotherapy
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11. Adding an invasive procedure will not necessarily change treatment or outcome of NSCLC patients with preoperative clinical N1 disease
by Decaluwé, Herbert and Dooms, Christophe and De Leyn, Paul and Thomas, Pascal and Rami-Porta, Ramon
European Respiratory Journal, ISSN 0903-1936, 04/2018, Volume 51, Issue 4, pp. 1800410 - 1800410
We would like to thank A. Addeo and G. Banna for their correspondence with comments on our article entitled “Mediastinal staging by videomediastinoscopy in... 
CELL LUNG-CANCER | RESPIRATORY SYSTEM | Carcinoma, Non-Small-Cell Lung | Lung Neoplasms | Humans | Non-small cell lung carcinoma | Event-related potentials | Invasiveness | Patients
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12. Full Text Parsimonious Eurolung risk models to predict cardiopulmonary morbidity and mortality following anatomic lung resections: an updated analysis from the European Society of Thoracic Surgeons database
by Brunelli, Alessandro and Cicconi, Silvia and Decaluwe, Herbert and Szanto, Zalan and Falcoz, Pierre Emmanuel
European Journal of Cardio-Thoracic Surgery, ISSN 1010-7940, 10/2019
Abstract OBJECTIVES To develop a simplified version of the Eurolung risk model to predict cardiopulmonary morbidity and 30-day mortality after lung resection... 
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13. Full Text Cons: Should a patient with stage IA non-small cell lung cancer undergo invasive mediastinal staging?
by Decaluwé, Herbert and Dooms, Christophe
Translational Lung Cancer Research, ISSN 2218-6751, 06/2016, Volume 5, Issue 3, pp. 251 - 253
SURVIVAL | SURGERY | POSITRON-EMISSION-TOMOGRAPHY | ONCOLOGY | RESPIRATORY SYSTEM | DISEASE | COMPUTED-TOMOGRAPHY | CHEMOTHERAPY | Pros and Cons | Controversies on Lung Cancer
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14. Full Text Surgical multimodality treatment for baseline resectable stage IIIA-N2 non-small cell lung cancer. Degree of mediastinal lymph node involvement and impact on survival
by Decaluwé, Herbert and De Leyn, Paul and Vansteenkiste, Johan and Dooms, Christophe and Van Raemdonck, Dirk and Nafteux, Philippe and Coosemans, Willy and Lerut, Toni
European Journal of Cardio-Thoracic Surgery, ISSN 1010-7940, 9/2009, Volume 36, Issue 3, pp. 433 - 439
Objective: Analysis of single centre results and identification of prognostic factors of surgical combined modality treatment in pathological proven stage... 
Non-small-cell lung cancer | Stage IIIA-N2 | Pneumonectomy | Positive mediastinal lymph nodes | Lobectomy | Induction therapy | SURGERY | CARDIAC & CARDIOVASCULAR SYSTEMS | INDUCTION CHEMOTHERAPY | PROGNOSTIC-FACTORS | RESECTION | PHASE-II TRIAL | POSITRON-EMISSION-TOMOGRAPHY | THERAPY | NEOADJUVANT CHEMOTHERAPY | RESPIRATORY SYSTEM | GUIDELINES 2ND EDITION | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - drug therapy | Carcinoma, Non-Small-Cell Lung - surgery | Prognosis | Mediastinum | Humans | Middle Aged | Lung Neoplasms - pathology | Male | Treatment Outcome | Lymphatic Metastasis | Carcinoma, Non-Small-Cell Lung - secondary | Pneumonectomy - methods | Epidemiologic Methods | Aged, 80 and over | Adult | Female | Lung Neoplasms - surgery | Neoadjuvant Therapy | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Chemotherapy, Adjuvant | Neoplasm Staging | Chemotherapy | Squamous cell carcinoma | Care and treatment | Lymphatic diseases | Analysis | Surgery | Lung cancer, Non-small cell | Health aspects | Cancer
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15. Full Text Rebuttal from Dr. Decaluwé and Dr. Dooms
by Decaluwé, Herbert and Dooms, Christophe
Translational Lung Cancer Research, ISSN 2218-6751, 06/2016, Volume 5, Issue 3, pp. 256 - 257
ONCOLOGY | RESPIRATORY SYSTEM | LUNG-CANCER PATIENTS | Pros and Cons | Controversies on Lung Cancer
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16. Full Text Characterization of Esophageal Motility in Infants With Congenital Diaphragmatic Hernia Using High-resolution Manometry
by Rayyan, Maissa and Omari, Taher and Debeer, Anne and Decaluwe, Herbert and Deprest, Jan and Allegaert, Karel and Rommel, Nathalie
Journal of Pediatric Gastroenterology and Nutrition, ISSN 0277-2116, 07/2019, Volume 69, Issue 1, pp. 32 - 38
OBJECTIVES:The aim of the study was to characterize esophageal motility and esophagogastric junction (EGJ) function in infants who underwent repair of an... 
Hernia | Care and treatment | Research | Diaphragm | Esophagogastric junction | Pediatric research
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17. Full Text Double‐lung versus heart‐lung transplantation for precapillary pulmonary arterial hypertension: a 24‐year single‐center retrospective study
by Brouckaert, Janne and Verleden, Stijn E and Verbelen, Tom and Coosemans, Willy and Decaluwé, Herbert and De Leyn, Paul and Depypere, Lieven and Nafteux, Philippe and Van Veer, Hans and Meyns, Bart and Rega, Filip and Van De Velde, Marc and Poortmans, Gert and Rex, Steffen and Neyrinck, Arne and Van den Berghe, Greet and Vlasselaers, Dirk and Van Cleemput, Johan and Budts, Werner and Vos, Robin and Quarck, Rozenn and Belge, Catharina and Delcroix, Marion and Verleden, Geert M and Van Raemdonck, Dirk
Transplant International, ISSN 0934-0874, 07/2019, Volume 32, Issue 7, pp. 717 - 729
Summary Transplant type for end‐stage pulmonary vascular disease remains debatable. We compared recipient outcome after heart‐lung (HLT) versus double‐lung... 
chronic thromboembolic pulmonary hypertension | congenital heart disease | lung transplantation | Eisenmenger syndrome | pulmonary vascular disease | pulmonary arterial hypertension | SURGERY | CONSENSUS GROUP STATEMENT | ISHLT WORKING GROUP | INTERNATIONAL SOCIETY | GRAFT DYSFUNCTION | BRIDGE | TRANSPLANTATION | EXTRACORPOREAL MEMBRANE-OXYGENATION | Transplantation of organs, tissues, etc | Congenital heart disease | Genetic disorders | Heart diseases | Analysis | Pulmonary hypertension | Hypertension | Transplants & implants | Syngeneic grafts | Connective tissue diseases | Heart transplantation | Lung diseases | Lung transplantation | Transplantation | Survival | Grafting | Coronary artery disease | Bleeding | Connective tissues | Vascular diseases | Xenografts | Cardiovascular diseases | Thromboembolism | Health risk assessment
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18. Full Text Diaphragm repair with a novel cross-linked collagen biomaterial in a growing rabbit model
by Mayer, Steffi and Decaluwe, Herbert and Ruol, Michele and Manodoro, Stefano and Kramer, Manuel and Till, Holger and Deprest, Jan
PLoS ONE, ISSN 1932-6203, 07/2015, Volume 10, Issue 7, p. e0132021
Background Neonates with congenital diaphragmatic hernia and large defects often require patch closure. Acellular collagen matrices (ACM) have been suggested... 
SMALL-INTESTINAL SUBMUCOSA | MESHES | METAANALYSIS | MANAGEMENT | TRACHEAL OCCLUSION | RECONSTRUCTION | MULTIDISCIPLINARY SCIENCES | PATCH REPAIR | ANIMAL-MODEL | ABDOMINAL-WALL DEFECTS | HERNIA REPAIR | Rabbits | Hernia, Diaphragmatic - surgery | Animals | Hernia, Diaphragmatic - pathology | Biocompatible Materials - chemistry | Collagen - chemistry | Materials Testing | Biocompatible Materials - pharmacology | Collagen - pharmacology | Hernia | Usage | Biological products | Genetic disorders | Tissue engineering | Collagen | Comparative analysis | Neonates | Pediatrics | Surgical implants | Thoracic surgery | Compliance | Liver | Prenatal development | Inflammatory response | Macrophages | Defects | Biomaterials | Finite element method | Biomedical materials | Bursting strength | Intestine | Surgery | Diaphragm (anatomy) | Repair | Explants | Reconstruction | Gynecology | Patches (structures) | Organs | Crosslinking | Inflammation | Gene expression | Obstetrics | Adhesion | Abdomen | Medicine | Studies | Hospitals | Lungs | Hernias | Fibrosis | Diaphragm
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