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1. Full Text Diagnosis and treatment of primary CNS lymphoma in immunocompetent patients: guidelines from the European Association for Neuro-Oncology
by Hoang-Xuan, Khê, Prof and Bessell, Eric, FRCR and Bromberg, Jacoline, MD and Hottinger, Andreas F, MD and Preusser, Matthias, MD and Rudà, Roberta, MD and Schlegel, Uwe, Prof and Siegal, Tali, Prof and Soussain, Carole, MD and Abacioglu, Ufuk, MD and Cassoux, Nathalie, MD and Deckert, Martina, Prof and Dirven, Clemens M F, Prof and Ferreri, Andrés J M, MD and Graus, Francesc, MD and Henriksson, Roger, Prof and Herrlinger, Ulrich, MD and Taphoorn, Martin, Prof and Soffietti, Riccardo, Prof and Weller, Michael, Prof and European Assoc Neuro-Oncology Task and European Association for Neuro-Oncology Task Force on Primary CNS Lymphoma and Medicinska fakulteten and Institutionen för strålningsvetenskaper and Onkologi and Umeå universitet
Lancet Oncology, The, ISSN 1470-2045, 2015, Volume 16, Issue 7, pp. e322 - e332
Summary The management of primary CNS lymphoma is one of the most controversial topics in neuro-oncology because of the complexity of the disease and the very... 
Hematology, Oncology and Palliative Medicine | INTENSIVE CHEMOTHERAPY | ONCOLOGY | RECURRENT PRIMARY CNS | MULTICENTER PHASE-II | HIGH-DOSE METHOTREXATE | TERM-FOLLOW-UP | NON-HODGKINS-LYMPHOMA | WHOLE-BRAIN RADIOTHERAPY | STEM-CELL TRANSPLANTATION | ELDERLY-PATIENTS | NERVOUS-SYSTEM LYMPHOMA | Prognosis | Humans | Male | Lymphoma - mortality | Lymphoma - therapy | Central Nervous System Neoplasms - immunology | Neoplasm Invasiveness - pathology | Female | Immunocompetence | Chemotherapy, Adjuvant | Radiotherapy, Adjuvant | Societies, Medical - standards | Lymphoma - diagnosis | Europe | Lymphoma - immunology | Central Nervous System Neoplasms - therapy | Combined Modality Therapy | Transplantation, Autologous - methods | Evidence-Based Medicine | Stem Cell Transplantation - methods | Survival Analysis | Neurosurgical Procedures - methods | Neoplasm Staging | Central Nervous System Neoplasms - diagnosis | Central Nervous System Neoplasms - mortality | Practice Guidelines as Topic | Clinical Medicine | Medical and Health Sciences | Cancer and Oncology | Klinisk medicin | Medicin och hälsovetenskap | Cancer och onkologi
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2. Full Text Chemoimmunotherapy with methotrexate, cytarabine, thiotepa, and rituximab (MATRix regimen) in patients with primary CNS lymphoma: results of the first randomisation of the International Extranodal Lymphoma Study Group-32 (IELSG32) phase 2 trial
by Ferreri, Andrés J M, Dr and Cwynarski, Kate, MD and Pulczynski, Elisa, MD and Ponzoni, Maurilio, Prof and Deckert, Martina, Prof and Politi, Letterio S, MD and Torri, Valter, MD and Fox, Christopher P, MD and Rosée, Paul La, MD and Schorb, Elisabeth, MD and Ambrosetti, Achille, Prof and Roth, Alexander, MD and Hemmaway, Claire, MD and Ferrari, Angela, MD and Linton, Kim M, PhD and Rudà, Roberta, MD and Binder, Mascha, Prof and Pukrop, Tobias, Prof and Balzarotti, Monica, MD and Fabbri, Alberto, MD and Johnson, Peter, Prof and Gørløv, Jette Sønderskov, PhD and Hess, Georg, MD and Panse, Jens, MD and Pisani, Francesco, MD and Tucci, Alessandra, MD and Stilgenbauer, Stephan, Prof and Hertenstein, Bernd, MD and Keller, Ulrich, Prof and Krause, Stefan W, Prof and Levis, Alessandro, MD and Schmoll, Hans J, MD and Cavalli, Franco, Prof and Finke, Jürgen, Prof and Reni, Michele, MD and Zucca, Emanuele, MD and Illerhaus, Gerald, Prof and IELSG and International Extranodal Lymphoma Study Group (IELSG)
Lancet Haematology, The, ISSN 2352-3026, 2016, Volume 3, Issue 5, pp. e217 - e227
Summary Background Standard treatment for patients with primary CNS lymphoma remains to be defined. Active therapies are often associated with increased risk... 
Hematology, Oncology and Palliative Medicine | 1ST-LINE TREATMENT | RESPONSE CRITERIA | GUIDELINES | NON-HODGKINS-LYMPHOMA | FOLLOW-UP | CENTRAL-NERVOUS-SYSTEM | WHOLE-BRAIN RADIOTHERAPY | HIGH-DOSE CHEMOTHERAPY | STEM-CELL TRANSPLANTATION | HEMATOLOGY | Follow-Up Studies | Cytarabine - therapeutic use | Humans | Lymphoma, B-Cell - therapy | Middle Aged | Male | Comparative Effectiveness Research | Hyperglycemia - chemically induced | Radiotherapy, Adjuvant - adverse effects | Hematopoietic Stem Cell Transplantation - adverse effects | Lymphoma, B-Cell - diagnostic imaging | Transplantation Conditioning - methods | Rituximab - adverse effects | Induction Chemotherapy - methods | Anemia - chemically induced | Central Nervous System Neoplasms - therapy | Thrombocytopenia - chemically induced | Mucositis - chemically induced | Magnetic Resonance Imaging | Methotrexate - adverse effects | Dexamethasone - therapeutic use | Radiotherapy, Adjuvant - methods | Transplantation, Autologous - adverse effects | Heart Injuries - chemically induced | Italy | Hematopoietic Stem Cell Transplantation - methods | Central Nervous System Neoplasms - mortality | Germany | Thiotepa - adverse effects | Thiotepa - therapeutic use | Thrombosis - chemically induced | Intraocular Lymphoma - therapy | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Cytarabine - adverse effects | Methotrexate - therapeutic use | Infection - chemically induced | Rituximab - therapeutic use | Stroke - chemically induced | Optic Nerve Neoplasms - diagnostic imaging | Poisoning - epidemiology | Female | Remission Induction - methods | Transplantation Conditioning - adverse effects | Acute Kidney Injury - chemically induced | Neutropenia - chemically induced | Optic Nerve Neoplasms - therapy | Death, Sudden - epidemiology | Lymphoma, B-Cell - mortality | Intraocular Lymphoma - diagnostic imaging | Kaplan-Meier Estimate | Chemical and Drug Induced Liver Injury - epidemiology | Treatment Outcome | United Kingdom | Combined Modality Therapy - adverse effects | Switzerland | Induction Chemotherapy - adverse effects | Disease-Free Survival | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Central Nervous System Neoplasms - diagnostic imaging | Denmark | Combined Modality Therapy - methods | Neurotoxicity Syndromes - epidemiology | Gastrointestinal Diseases - chemically induced
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3. Full Text High-dose chemotherapy with autologous haemopoietic stem cell transplantation for newly diagnosed primary CNS lymphoma: a prospective, single-arm, phase 2 trial
by Illerhaus, Gerald, Prof and Kasenda, Benjamin, PhD and Ihorst, Gabriele, PhD and Egerer, Gerlinde, MD and Lamprecht, Monika, MD and Keller, Ulrich, MD and Wolf, Hans-Heinrich, MD and Hirt, Carsten, MD and Stilgenbauer, Stephan, MD and Binder, Mascha, Prof and Hau, Peter, Prof and Edinger, Matthias, MD and Frickhofen, Norbert, MD and Bentz, Martin, MD and Möhle, Robert, MD and Röth, Alexander, MD and Pfreundschuh, Michael, Prof and von Baumgarten, Louisa, MD and Deckert, Martina, Prof and Hader, Claudia, MD and Fricker, Heidi and Valk, Elke, PhD and Schorb, Elisabeth, MD and Fritsch, Kristina, MD and Finke, Jürgen, MD
Lancet Haematology, The, ISSN 2352-3026, 2016, Volume 3, Issue 8, pp. e388 - e397
Summary Background High-dose methotrexate-based chemotherapy is standard for primary CNS lymphoma, but most patients relapse. High-dose chemotherapy with... 
Hematology, Oncology and Palliative Medicine | 1ST-LINE TREATMENT | CENTER EXPERIENCE | RESPONSE CRITERIA | CLINICAL-TRIALS | PLUS RITUXIMAB | NON-HODGKIN-LYMPHOMA | FOLLOW-UP | CENTRAL-NERVOUS-SYSTEM | WHOLE-BRAIN RADIOTHERAPY | HEMATOLOGY | RADIATION-THERAPY | Prognosis | Prospective Studies | Follow-Up Studies | Thiotepa - administration & dosage | Humans | Middle Aged | Hematopoietic Stem Cell Transplantation | Central Nervous System Neoplasms - therapy | Male | Survival Rate | Transplantation, Autologous | Combined Modality Therapy | Rituximab - administration & dosage | Young Adult | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Lymphoma, Non-Hodgkin - therapy | Adolescent | Adult | Female | Methotrexate - administration & dosage | Aged | Central Nervous System Neoplasms - diagnosis | Carmustine - administration & dosage | Lymphoma, Non-Hodgkin - diagnosis | Index Medicus
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4. Full Text Das Tumorepigenom – von der Genregulation über die Tumorklassifikation zum Therapietarget
by Ammerpohl, Ole and Ammerpohl, Ole and Deckert, Martina and Deckert, Martina and Montesinos-Rongen, Manuel and Montesinos-Rongen, Manuel
medizinische genetik, ISSN 0936-5931, 12/2016, Volume 28, Issue 4, pp. 424 - 434
Epigenetische Regulationsmechanismen sind essenziell für den koordinierten Ablauf zahlreicher zellulärer Prozesse wie die Differenzierung und Entwicklung oder... 
Human Genetics | Pediatrics | Epigenetik | Medicine & Public Health | MGMT | Obstetrics/Perinatology | Tumorepigenom | Epigenetics | DNA methylation | DNA-Methylierung | Reproductive Medicine | Tumor epigenome
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5. Full Text The Diagnosis and Treatment of Primary CNS Lymphoma
by von Baumgarten, L and Illerhaus, G and Korfel, A and Schlegel, U and Deckert, M and Dreyling, M
DEUTSCHES ARZTEBLATT INTERNATIONAL, ISSN 1866-0452, 06/2018, Volume 115, Issue 25, pp. 419 - 419
Background: Primary central nervous system lymphoma is a diffuse large B-cell lymphoma with exclusive manifestation in the central nervous system (CNS),... 
MEDICINE, GENERAL & INTERNAL | DIFFERENTIAL-DIAGNOSIS | INTENSIVE CHEMOTHERAPY | MULTICENTER PHASE-II | IMMUNOCOMPETENT PATIENTS | CENTRAL-NERVOUS-SYSTEM | WHOLE-BRAIN RADIOTHERAPY | HIGH-DOSE CHEMOTHERAPY | QUALITY-OF-LIFE | STEM-CELL TRANSPLANTATION | INTERNATIONAL EXTRANODAL LYMPHOMA
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6. Full Text Stereotactic interstitial brachytherapy for the treatment of oligodendroglial brain tumors
by El Majdoub, Faycal and Neudorfer, Clemens and Blau, Tobias and Hellmich, Martin and Bührle, Christian and Deckert, Martina and Sturm, Volker and Maarouf, Mohammad
Strahlentherapie und Onkologie, ISSN 0179-7158, 12/2015, Volume 191, Issue 12, pp. 936 - 944
We evaluated the treatment of oligodendroglial brain tumors with interstitial brachytherapy (IBT) using 125iodine seeds (125I) and analyzed prognostic... 
Iod-125 | Local control | Krankheitsfreies Überleben | Oncology | Oligoastrozytom | Oligoastrocytoma | Radiotherapy | Oligodendroglioma | Iodine-125 | Medicine & Public Health | Disease-free survival | Lokale Kontrolle | Oligodendrogliom | PROGNOSTIC-FACTORS | EUROPEAN ORGANIZATION | IMPLANTED I-125 SEEDS | PCV CHEMOTHERAPY | RANDOMIZED-TRIAL | RADIATION-THERAPY | PHASE-III TRIAL | ONCOLOGY | ANAPLASTIC OLIGODENDROGLIOMA | LOW-GRADE GLIOMA | MALIGNANT GLIOMAS | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Oligodendroglioma - mortality | Prognosis | Humans | Middle Aged | Brachytherapy - methods | Neoplasm Recurrence, Local | Salvage Therapy | Male | Combined Modality Therapy | Oligodendroglioma - radiotherapy | Disease Progression | Stereotaxic Techniques | Young Adult | Disease-Free Survival | Iodine Radioisotopes - therapeutic use | Adult | Female | Brain Neoplasms - mortality | Brain Neoplasms - radiotherapy | Radiotherapy, Adjuvant
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7. Full Text Novel Isolated Cerebral AL[lamda] Amyloid Angiopathy With Widespread Subcortical Distribution and Leukoencephalopathy Due to Atypical Monoclonal Plasma Cell Proliferation, and Terminal Systemic Gammopathy
by Roland Schröder and Martina Deckert and Reinhold P Linke
Journal of Neuropathology and Experimental Neurology, ISSN 0022-3069, 03/2009, Volume 68, Issue 3, p. 286
  Neuropathologic and biochemical findings in a 34-year-old man whose disease began 2 years before death appearing as chronic progressive encephalitis and... 
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8. Full Text CD4 T Cells Mediate Axonal Damage and Spinal Cord Motor Neuron Apoptosis in Murine P0 106–125-Induced Experimental Autoimmune Neuritis
by Brunn, Anna and Utermöhlen, Olaf and Carstov, Mariana and Ruiz, Monica Sánchez and Miletic, Hrvoje and Schlüter, Dirk and Deckert, Martina
The American Journal of Pathology, ISSN 0002-9440, 2008, Volume 173, Issue 1, pp. 93 - 105
The pathogenesis of inflammatory autoimmune diseases of the peripheral nervous system, leading to demyelination and/or axonal damage, remains incompletely... 
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9. Full Text Expression pattern and cellular origin of cytokines in the normal and Toxoplasma gondii-infected murine brain
by Schluter, D and Kaefer, N and Hof, H and Wiestler, OD and Deckert-Schluter, M
American Journal of Pathology, ISSN 0002-9440, 03/1997, Volume 150, Issue 3, pp. 1021 - 1035
In the normal brain, low levels of cytokines are observed, whereas inflammatory disorders of the central nervous system are characterized by an up-regulation... 
LISTERIA-MONOCYTOGENES | TUMOR-NECROSIS-FACTOR | CD4+ T-CELLS | INTERFERON-GAMMA | CENTRAL-NERVOUS-SYSTEM | PATHOLOGY | NITRIC-OXIDE MECHANISM | CLASS-II ANTIGENS | ACTIVATED MICROGLIA | CEREBROSPINAL-FLUID | K TM PATHOLOGY | FACTOR-ALPHA | Immunohistochemistry | Toxoplasmosis, Animal - metabolism | Up-Regulation | RNA, Messenger - analysis | Nerve Growth Factors - metabolism | Encephalitis - parasitology | Brain - metabolism | Lymphocyte Subsets - metabolism | Flow Cytometry | Immunomagnetic Separation | In Situ Hybridization | Lymphocyte Subsets - cytology | Base Sequence | Encephalitis - metabolism | Polymerase Chain Reaction | Female | Cytokines - genetics | Brain - parasitology | Brain - cytology | Immunophenotyping | Toxoplasma - isolation & purification | Animals | Mice | Mice, Inbred BALB C | Lymphocyte Subsets - parasitology | Cytokines - biosynthesis | Toxoplasmosis, Animal - pathology
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10. Full Text Primäre ZNS-Lymphome
: Aktuelle Standards bei Diagnostik und Therapie
by Schlegel, Uwe and Korfel, Agnieszka and Kortmann, Rolf and Deckert, Martina and Schackert, Gabriele
best practice onkologie, ISSN 0946-4565, 2/2010, Volume 5, Issue 1, pp. 26 - 35
Primäre ZNS-Lymphome sind in meist aggressive, rasch wachsende Non-Hodgkin-Lymphome vom B-Zell-Typ. Die Diagnostik erfolgt mittels zerebraler... 
Pain Medicine | Medicine & Public Health | Hematology | Gynecology | Internal Medicine | Oncology | Surgical Oncology
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11. Full Text Combined Surgery, Radiation, and PCV Chemotherapy for Astrocytomas Compared to Oligodendrogliomas and Oligoastrocytomas WHO Grade III
by Kristof, Rudolf A and Neuloh, Georg and Hans, Volkmar and Deckert, Martina and Urbach, Horst and Schlegel, Uwe and Simon, Matthias and Schramm, Johannes
Journal of Neuro-Oncology, ISSN 0167-594X, 9/2002, Volume 59, Issue 3, pp. 231 - 237
The time to tumor progression (TTP), time to death (TTD) and complications were studied prospectively in a cohort of patients treated by surgery and adjuvant... 
anaplastic oligoastrocytoma | Medicine & Public Health | radiation | anaplastic astrocytoma | Oncology | PCV chemotherapy | anaplastic oligodendroglioma | surgery | Anaplastic oligoastrocytoma | Surgery | Anaplastic astrocytoma | Anaplastic oligodendroglioma | Radiation | ADJUVANT CHEMOTHERAPY | VINCRISTINE PCV | LOMUSTINE | PHASE-II | PROCARBAZINE | CLINICAL NEUROLOGY | MALIGNANT GLIOMA | ONCOLOGY | CCNU | Astrocytoma - radiotherapy | Oligodendroglioma - surgery | Prospective Studies | Astrocytoma - therapy | Follow-Up Studies | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Vinblastine - therapeutic use | Oligodendroglioma - radiotherapy | Brain Neoplasms - surgery | Taxoids | Vinblastine - analogs & derivatives | Vinblastine - adverse effects | Astrocytoma - drug therapy | Adult | Female | Brain Neoplasms - radiotherapy | Oligodendroglioma - drug therapy | World Health Organization | Paclitaxel - adverse effects | Survival Rate | Treatment Outcome | Combined Modality Therapy | Brain Neoplasms - drug therapy | Radiotherapy | Paclitaxel - therapeutic use | Disease Progression | Oligodendroglioma - therapy | Cisplatin - therapeutic use | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Hematologic Diseases - etiology | Brain Neoplasms - therapy | Cisplatin - adverse effects | Neoplasm Staging | Astrocytoma - surgery | Cohort Studies
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12. Full Text Sphingolipid metabolism in neural cells
by van Echten-Deckert, Gerhild and Herget, Thomas
BBA - Biomembranes, ISSN 0005-2736, 2006, Volume 1758, Issue 12, pp. 1978 - 1994
Sphingolipids were discovered more than a century ago in the brain. Cerebrosides and sphingomyelins were named so because they were first isolated from neural... 
Sphingolipid | Ceramide | Metabolomic | Neuron | Neuroblastoma | Gangliosides | AMYLOID BETA-PROTEIN | sphingolipid | BIOCHEMISTRY & MOLECULAR BIOLOGY | PRIMARY CULTURED NEURONS | gangliosides | neuron | neuroblastoma | URIDINE DIPHOSPHATE-GALACTOSE | GALACTOSE-CERAMIDE GALACTOSYLTRANSFERASE | UDP-SUGAR PYROPHOSPHATASE | EMBRYONIC CHICKEN BRAIN | ceramide | metabolomic | BIOPHYSICS | THIN-LAYER-CHROMATOGRAPHY | CENTRAL-NERVOUS-SYSTEM | RAT-BRAIN | GANGLIOSIDE BIOSYNTHESIS
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