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PLoS ONE, ISSN 1932-6203, 07/2013, Volume 8, Issue 7, p. e69115
Compound A possesses glucocorticoid receptor (GR)-dependent anti-inflammatory properties. Just like classical GR ligands, Compound A can repress NF-kappa... 
TUMOR-NECROSIS-FACTOR | PROTEASOME INHIBITION LEADS | KAPPA-B INHIBITION | CANCER CELLS | RNA ACTIVATOR | MOLECULAR CHAPERONES | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | BETA-CATENIN | EXPRESSION | BINDING | Humans | Transcriptional Activation | NF-kappa B - metabolism | Receptors, Glucocorticoid - metabolism | Anti-Inflammatory Agents - metabolism | Heat Shock Transcription Factors | Receptors, Glucocorticoid - agonists | DNA-Binding Proteins - metabolism | Dose-Response Relationship, Drug | Female | Cell Line | Promoter Regions, Genetic | NF-kappa B - antagonists & inhibitors | Response Elements | Anti-Inflammatory Agents - pharmacology | HSP70 Heat-Shock Proteins - genetics | HSP70 Heat-Shock Proteins - metabolism | Gene Expression Regulation - drug effects | Transcription Factors - metabolism | Animals | Anti-Inflammatory Agents - chemistry | Models, Biological | HSP90 Heat-Shock Proteins - metabolism | Protein Binding | Mice | Corticosteroids | RNA | Tumor necrosis factor | Genes | Heat shock proteins | Protein biosynthesis | Inflammation | Genetic transcription | Steroids | Biomedical research | Transcription | Glucocorticoids | Laboratories | Epithelial cells | Pathogenesis | Oncology | Activation | Biochemistry | Kinases | Heat shock factors | Degradation | Tumor necrosis factor-TNF | HSF1 protein | Translocation | Compound A | NF-κB protein | Medical research | Antiinflammatory agents | Cytokines | Research & development--R&D | Hsp70 protein | Radiation therapy | Gene expression | Nuclear transport | Lungs | Protein synthesis | Cell lines | Proteasomes | Ligands | Cancer | Apoptosis | Heat shock | Research & development | R&D
Journal Article
Journal Article
Immunity, ISSN 1074-7613, 2011, Volume 35, Issue 6, pp. 908 - 918
Journal Article
BBA - Molecular Cell Research, ISSN 0167-4889, 12/2013, Volume 1833, Issue 12, pp. 3471 - 3480
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 05/2016, Volume 136, Issue 5, pp. 891 - 892
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2017, Volume 141, Issue 2, pp. 549 - 559.e7
Background Chronic airway inflammatory diseases, such as chronic rhinosinusitis with nasal polyps and asthma, show increased nasal Staphylococcus aureus... 
Allergy and Immunology | Allergy | asthma | sensitization | serine protease | Staphylococcus aureus | DENDRITIC CELLS | ENTEROTOXIN-B | ALLERGIC LUNG INFLAMMATION | INNATE LYMPHOID-CELLS | IMMUNOLOGY | HOUSE-DUST MITE | THYMIC STROMAL LYMPHOPOIETIN | ATOPIC-DERMATITIS | IN-VITRO | IMMUNE-RESPONSES | Interleukin-1 Receptor-Like 1 Protein - immunology | Signal Transduction - genetics | Th2 Cells - immunology | CD4-Positive T-Lymphocytes - pathology | Interleukin-33 - immunology | Staphylococcus aureus - pathogenicity | Asthma - chemically induced | Asthma - genetics | Mice, Knockout | CD4-Positive T-Lymphocytes - immunology | Interleukin-33 - genetics | Serine Proteases - toxicity | Animals | Bacterial Proteins - toxicity | Signal Transduction - drug effects | Asthma - immunology | Staphylococcus aureus - immunology | Mice | Interleukin-1 Receptor-Like 1 Protein - genetics | Th2 Cells - pathology | Disease Models, Animal | Immunohistochemistry | Allergens | Flow cytometry | Animal models | Adaptive systems | Recombination | Hyperreactivity | Hyperplasia | Immunoglobulin E | Inflammatory response | Lymphocytes T | RAG gene | Inflammatory diseases | Lymph nodes | Eotaxin | Proteins | Interleukin 5 | Lymphocytes | Protease | Rodents | Toll-like receptors | Respiratory tract diseases | Enzyme-linked immunosorbent assay | Inducers | Immune system | Recombinant | Lymphoid cells | Cytokines | Dendritic cells | Leukocytes (eosinophilic) | Hypersensitivity | Protein D | Inflammation | Interleukin 13 | Eosinophilia | Allergies | Asthma | CD4 antigen | Cytometry | Signaling | Software | Polyps | Eosinophils
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 513, Issue 7516, pp. 95 - 99
Receptor interacting protein kinase 1 (RIPK1) has an essential role in the signalling triggered by death receptors and pattern recognition receptors(1,2).... 
UBIQUITINATION | NECROPTOSIS | MEDIATED RECOMBINATION | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | KINASE | MICE | TNF-ALPHA | CRE-LOXP | NECROSIS-FACTOR RECEPTOR-1 | CELL-DEATH | Intestines - drug effects | Protein Kinases - metabolism | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Inflammation - pathology | Epithelial Cells - metabolism | Apoptosis - drug effects | Epithelial Cells - drug effects | Caspase 8 - metabolism | Male | NF-kappa B - metabolism | Intestines - metabolism | Organoids - enzymology | Necrosis | Caspase 8 - genetics | Receptors, Tumor Necrosis Factor, Type I - deficiency | Inflammation - metabolism | Gene Deletion | Organoids - metabolism | Female | Homeostasis - drug effects | Epithelial Cells - cytology | Tumor Necrosis Factors - pharmacology | Cell Survival - drug effects | Epithelium - drug effects | Epithelium - pathology | Intestines - pathology | Epithelium - metabolism | Organoids - cytology | Epithelial Cells - pathology | Mice, Knockout | Receptor-Interacting Protein Serine-Threonine Kinases - genetics | Animals | Myeloid Differentiation Factor 88 - deficiency | Organoids - drug effects | Survival Analysis | Anti-Bacterial Agents - pharmacology | Mice | Receptor-Interacting Protein Serine-Threonine Kinases - deficiency | Intestines - cytology | Protein research | Physiological aspects | Homeostasis | Research | Epithelium | Protein kinases | Apoptosis | Proteins | Genotype & phenotype | Antibiotics | Transgenic animals | Rodents | Ligands | Colon | Kinases
Journal Article