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Drug Metabolism and Disposition, ISSN 0090-9556, 07/2017, Volume 45, Issue 7, pp. 807 - 816
Journal Article
PLoS Genetics, ISSN 1553-7390, 05/2014, Volume 10, Issue 5
  The hepatic circadian clock plays a key role in the daily regulation of glucose metabolism, but the precise molecular mechanisms that coordinate these two... 
Rodents | Liver | Circadian rhythm | Glucose | Insulin | Metabolic disorders
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2014, Volume 9, Issue 10, p. e110162
Fatty liver disease is an emerging public health problem without effective therapies, and chronic hepatic inflammation is a key pathologic mediator in its... 
SOLUBLE EPOXIDE HYDROLASE | HYDRODYNAMICS-BASED TRANSFECTION | MULTIDISCIPLINARY SCIENCES | MOUSE | ATHEROGENIC DIET | NONALCOHOLIC STEATOHEPATITIS | EICOSANOID METABOLISM | MICE | ARACHIDONIC-ACID | LARGE GENE LISTS | ENDOTHELIAL EXPRESSION | Biomarkers - metabolism | Fatty Liver - genetics | Epoxide Hydrolases - deficiency | Inflammation - pathology | Arachidonic Acid - metabolism | Liver - pathology | Liver - enzymology | Fatty Liver - blood | Fatty Liver - pathology | Mice, Inbred C57BL | Gene Expression Regulation | Cytochrome P-450 Enzyme System - metabolism | Hydrodynamics | Male | Inflammation - blood | Metabolic Networks and Pathways - genetics | Animals | Diet | Eicosanoids - metabolism | Lipids - blood | Atherosclerosis | Fatty Liver - enzymology | Inflammation - genetics | Epoxide Hydrolases - metabolism | Unsaturated fatty acids | Inflammation | Fatty liver | Analysis | Cytochrome P-450 | Cytochrome | Health sciences | Liver | Inflammatory response | Cardiovascular disease | Biosynthesis | Arachidonic acid | Phosphatase | Epoxide hydrolase | Biological effects | Atherogenic diet | Rodents | Hepatology | Drug therapy | Pharmaceutical sciences | Public health | Cardiovascular system | Enzymes | Liver diseases | Cytochrome P450 | Environmental health | Metabolism | Gene expression | Cholesterol | Biological activity | Nutrition research | Acids | Pharmacy | Mice | Laboratory animals | Apoptosis
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2013, Volume 8, Issue 3, p. e58417
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 07/2017, Volume 45, Issue 7, p. 807
The CYP2C subfamily of the cytochrome P450 gene superfamily encodes heme-thiolate proteins that have a myriad of biologic functions. CYP2C proteins detoxify... 
Cytochrome | Stomach | Duodenum | Liver | Cytochrome P450 | Eicosanoids | Lipids | Assaying | Arachidonic acid | Proteins | Polymerase | Jejunum | Large intestine | Isoforms | Heme | Lipid metabolism | Xenobiotics
Journal Article
FASEB Journal, ISSN 0892-6638, 02/2011, Volume 25, Issue 2, pp. 703 - 713
Journal Article
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2013, Volume 8, Issue 8, p. e73490
Maladaptive cardiac hypertrophy predisposes one to arrhythmia and sudden death. Cytochrome P450 (CYP)-derived epoxyeicosatrienoic acids (EETs) promote... 
SOLUBLE EPOXIDE HYDROLASE | CYTOCHROME-P450 | GAP-JUNCTIONS | INHIBITION | SENSITIVE K+ CHANNELS | MULTIDISCIPLINARY SCIENCES | MOLECULAR-CLONING | MECHANISMS | MODEL | EPOXYEICOSATRIENOIC ACIDS | EXPRESSION | Endomyocardial Fibrosis - enzymology | Humans | Disease Susceptibility - physiopathology | Cytochrome P-450 Enzyme System - metabolism | Male | Arrhythmias, Cardiac - physiopathology | Aortic Valve Stenosis - enzymology | Ventricular Remodeling | Endomyocardial Fibrosis - complications | Endomyocardial Fibrosis - pathology | Disease Susceptibility - pathology | Receptors, Adrenergic, beta - metabolism | Biomarkers - metabolism | Arrhythmias, Cardiac - prevention & control | Connexin 43 - metabolism | Disease Susceptibility - complications | Aortic Valve Stenosis - physiopathology | Disease Susceptibility - enzymology | Cardiomegaly - physiopathology | Mice, Transgenic | Arrhythmias, Cardiac - etiology | Cardiomegaly - enzymology | Pressure | Cardiomegaly - complications | Aortic Valve Stenosis - complications | Animals | Aortic Valve Stenosis - pathology | Survival Analysis | Arrhythmias, Cardiac - enzymology | Endomyocardial Fibrosis - physiopathology | Mice | Electrophysiological Phenomena | Chronic Disease | Heart | Tachycardia | Heart enlargement | Atrial fibrillation | Cytochrome P-450 | Physiological aspects | Genetic engineering | Comparative analysis | Health aspects | Cytochrome | Health sciences | Cardiac arrhythmia | Calcium | Arrhythmia | Tachyarrhythmia | Stimulation | Biosynthesis | Connexin 43 | Isoproterenol | Remodeling | Eutrophication | Infusion | Fibrillation | Thermal resistance | Ischemia | Transgenic animals | Rodents | Cooperation | Aorta | Heart diseases | Heart failure | Hypertension | Mortality | Cytochrome P450 | Environmental health | Transgenic mice | Inflammation | Medicine | Fibrosis | In vivo methods and tests | Ventricle | Prolongation | Hypertrophy
Journal Article
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 11/2011, Volume 301, Issue 5, pp. 645 - 655
Journal Article