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Cell reports (Cambridge), ISSN 2211-1247, 2016, Volume 16, Issue 10, pp. 2576 - 2592
The mechanisms underlying Zika virus (ZIKV)-related microcephaly and other neurodevelopment defects remain poorly understood. Here, we describe the derivation... 
NEURAL PROGENITORS | LONG-TERM | HUMAN BRAIN | ADAPTER | CENTRAL-NERVOUS-SYSTEM | INFECTION | MICE | BINDING KINASE 1 | ORGANOIDS | INNATE IMMUNITY | CELL BIOLOGY | Neocortex - pathology | Neurons - pathology | Transcription, Genetic - drug effects | Brain - embryology | Neuroglia - ultrastructure | Neuroglia - pathology | Humans | Brain - virology | Centrosome - drug effects | Gene Expression Profiling | Microcephaly - virology | Neural Stem Cells - ultrastructure | Zika Virus Infection - virology | Neural Stem Cells - immunology | Neuroepithelial Cells - immunology | Neuroprotective Agents - pharmacology | Spinal Cord - pathology | Microcephaly - pathology | Neuroepithelial Cells - virology | Nucleosides - pharmacology | Fetus - virology | Cell Death - drug effects | Phosphorylation - drug effects | Neurons - drug effects | Protein-Serine-Threonine Kinases - metabolism | Zika Virus - pathogenicity | Proto-Oncogene Proteins - metabolism | Zika Virus - ultrastructure | Neurons - virology | Virus Replication - drug effects | Neuroepithelial Cells - ultrastructure | Immunity, Innate - drug effects | Zika Virus Infection - pathology | Neural Stem Cells - virology | Zika Virus - physiology | Zika Virus - drug effects | Mitochondria - metabolism | Mitochondria - drug effects | Receptor Protein-Tyrosine Kinases - metabolism | Neural Stem Cells - enzymology | Centrosome - metabolism | Mitosis - drug effects | Brain - pathology | Protein Kinase Inhibitors - pharmacology | Neuroglia - virology | Neuroepithelial Cells - drug effects | Neurons/pathology | Zika Virus/pathogenicity | Mitochondria/metabolism | Virus Replication/drug effects | Microcephaly/pathology | Neurons/drug effects | Protein-Serine-Threonine Kinases/metabolism | Neural Stem Cells/immunology | Neuroglia/ultrastructure | Neuroepithelial Cells/drug effects | Neuroepithelial Cells/virology | Life Sciences | Brain/pathology | Zika Virus/drug effects | Brain/embryology | Mitochondria/drug effects | Fetus/virology | Neocortex/pathology | Neuroglia/pathology | Cell Death/drug effects | Mitosis/drug effects | Transcription, Genetic/drug effects | Nucleosides/pharmacology | Neural Stem Cells/enzymology | Neural Stem Cells/ultrastructure | Neuroepithelial Cells/ultrastructure | Receptor Protein-Tyrosine Kinases/metabolism | Microcephaly/virology | Proto-Oncogene Proteins/metabolism | Neuroprotective Agents/pharmacology | Zika Virus/ultrastructure | Neuroepithelial Cells/immunology | Brain/virology | Immunity, Innate/drug effects | Spinal Cord/pathology | Zika Virus/physiology | Neuroglia/virology | Microbiology and Parasitology | Zika Virus Infection/pathology | Neurons/virology | Zika Virus Infection/virology | Neural Stem Cells/virology | Centrosome/drug effects | Protein Kinase Inhibitors/pharmacology | Centrosome/metabolism | Phosphorylation/drug effects
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 2014, Volume 124, Issue 7, pp. 3215 - 3229
Journal Article
Nature (London), ISSN 1476-4687, 2011, Volume 476, Issue 7359, pp. 224 - 227
Journal Article
Stem cells translational medicine, ISSN 2157-6564, 2013, Volume 2, Issue 6, pp. 473 - 479
Current protocols for in vitro differentiation of human induced pluripotent stem cells (hiPSCs) to generate dopamine (DA) neurons are laborious and... 
Direct cell conversion | Reprogramming | Neuron | Dopamine | Pluripotent stem cells | DERIVATION | HUMAN ES | MOUSE | EFFICIENT GENERATION | IPS CELLS | CELL & TISSUE ENGINEERING | MODELS | HUMAN FIBROBLASTS | MIDBRAIN | PARKINSONS-DISEASE | Biomarkers - metabolism | Basic Helix-Loop-Helix Transcription Factors - genetics | Induced Pluripotent Stem Cells - physiology | LIM-Homeodomain Proteins - metabolism | Humans | Cells, Cultured | Tubulin - genetics | Nuclear Receptor Subfamily 4, Group A, Member 2 - genetics | Transcription Factors - genetics | Membrane Potentials - physiology | Cell Lineage - physiology | Dopaminergic Neurons - cytology | Transcription Factors - metabolism | LIM-Homeodomain Proteins - genetics | Tubulin - metabolism | Basic Helix-Loop-Helix Transcription Factors - metabolism | Gene Expression Regulation, Developmental | Dopaminergic Neurons - physiology | Lentivirus - genetics | Cell Differentiation | Nuclear Receptor Subfamily 4, Group A, Member 2 - metabolism | Genetic Vectors | Induced Pluripotent Stem Cells - cytology | Dopamine - metabolism | ASCL1 protein | Data analysis | Transcription factors | Neurons | Parkinsons disease | Cell lineage | Nuclear receptors | Neurogenesis | Nurr1 protein | Efficiency | Morphology | Stem cells | Fibroblasts | Neural stem cells | Pluripotency | Dopamine receptors | Tissue Engineering and Regenerative Medicine
Journal Article
Journal Article
Neuropharmacology, ISSN 0028-3908, 03/2013, Volume 66, pp. 179 - 186
Group I metabotropic glutamate receptors (mGluRs), which comprise mGlu1Rs and mGlu5Rs, are enriched in striatal medium spiny neurons (MSNs), where they... 
Striatum | Basal ganglia | Mouse | Adenosine A2A receptor | Metabotropic glutamate receptor | POSITIVE ALLOSTERIC MODULATOR | ADENOSINE A(2A) | RAT STRIATUM | BINDING CHARACTERISTICS | NEUROSCIENCES | ANTIPSYCHOTIC-LIKE | DARPP-32 PHOSPHORYLATION | PHARMACOLOGY & PHARMACY | ACCUMULATION | DOPAMINE-D-2 RECEPTORS | EXPRESSION | Phosphorylation - physiology | Glycine - analogs & derivatives | Dopamine and cAMP-Regulated Phosphoprotein 32 - genetics | Receptors, Metabotropic Glutamate - physiology | Male | Receptor, Adenosine A2A - physiology | Purinergic P1 Receptor Antagonists - pharmacology | Resorcinols - pharmacology | Neurons - physiology | Receptor, Metabotropic Glutamate 5 | Phosphorylation - drug effects | Neurons - drug effects | Receptors, AMPA - metabolism | Cyclic AMP-Dependent Protein Kinases - metabolism | Triazines - pharmacology | Mice, Inbred C57BL | Receptors, Dopamine D2 - agonists | Excitatory Amino Acid Agonists - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Dopamine and cAMP-Regulated Phosphoprotein 32 - metabolism | Mice, Knockout | Triazoles - pharmacology | Animals | Glycine - antagonists & inhibitors | Glycine - pharmacology | Signal Transduction - drug effects | Receptors, Dopamine D1 - physiology | Corpus Striatum - drug effects | Corpus Striatum - physiology | Receptors, Dopamine D2 - physiology | Resorcinols - antagonists & inhibitors | Signal Transduction - physiology | Mice | Pyridines - pharmacology | Receptors, Metabotropic Glutamate - agonists | Methyl aspartate | Enzymes | Neurosciences | Pyridine | Neurons | Dimethyl sulfoxide | Glutamate | Protein kinases | Adenosine A2A receptors
Journal Article
Journal of Molecular Cell Biology, ISSN 1674-2788, 12/2011, Volume 3, Issue 6, pp. 322 - 323
Journal Article
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