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1. Full Text A comparison of methods for differential expression analysis of RNA-seq data
by Soneson, Charlotte and Delorenzi, Mauro
BMC bioinformatics, ISSN 1471-2105, 03/2013, Volume 14, Issue 1, pp. 91 - 91
RNA-seq | Differential expression | Gene expression | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Biochemical Research Methods | Science & Technology | Mathematical & Computational Biology | Animals | Sequence Analysis, RNA | Mice, Inbred C57BL | DNA, Complementary - genetics | Gene Expression Profiling - methods | Mice, Inbred DBA | Mice | Software | Genome | Genomics - methods | RNA, Messenger - metabolism | RNA sequencing | Messenger RNA | DNA microarrays | Computational biology | Studies | Binomial distribution | Libraries | Genomes | Experiments | Bioinformatics | Index Medicus | Abundance
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2. Full Text Effects of KRAS, BRAF, NRAS , and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis
by De Roock, Wendy, MD and Claes, Bart, MSc and Bernasconi, David, MSc and De Schutter, Jef, MSc and Biesmans, Bart, MSc and Fountzilas, George, Prof and Kalogeras, Konstantine T, MD and Kotoula, Vassiliki, MD and Papamichael, Demetris, FRCP and Laurent-Puig, Pierre, Prof and Penault-Llorca, Frédérique, Prof and Rougier, Philippe, Prof and Vincenzi, Bruno, MD and Santini, Daniele, MD and Tonini, Giuseppe, Prof and Cappuzzo, Federico, MD and Frattini, Milo, PhD and Molinari, Francesca, PhD and Saletti, Piercarlo, MD and De Dosso, Sara, MD and Martini, Miriam, PhD and Bardelli, Alberto, Prof and Siena, Salvatore, Prof and Sartore-Bianchi, Andrea, MD and Tabernero, Josep, Prof and Macarulla, Teresa, MD and Di Fiore, Frédéric, MD and Gangloff, Alice Oden, MD and Ciardiello, Fortunato, Prof and Pfeiffer, Per, Prof and Qvortrup, Camilla, MD and Hansen, Tine Plato, MD and Van Cutsem, Eric, Prof and Piessevaux, Hubert, Prof and Lambrechts, Diether, Prof and Delorenzi, Mauro, PhD and Tejpar, Sabine, Prof
The lancet oncology, ISSN 1470-2045, 2010, Volume 11, Issue 8, pp. 753 - 762
Hematology, Oncology and Palliative Medicine | Life Sciences & Biomedicine | Oncology | Science & Technology | Multivariate Analysis | Colorectal Neoplasms - genetics | Humans | Middle Aged | Male | Antibodies, Monoclonal, Humanized | Colorectal Neoplasms - drug therapy | Aged, 80 and over | Adult | Female | Antineoplastic Agents - pharmacology | Retrospective Studies | Cetuximab | Genes, ras - genetics | Antibodies, Monoclonal - pharmacology | Proportional Hazards Models | Antineoplastic Combined Chemotherapy Protocols | Phosphatidylinositol 3-Kinases - genetics | Drug Resistance, Neoplasm - genetics | Class I Phosphatidylinositol 3-Kinases | Antibodies, Monoclonal - administration & dosage | Proto-Oncogene Proteins B-raf - genetics | Survival Analysis | ROC Curve | Aged | Biomarkers, Tumor - genetics | Mutation | Medical colleges | Molecular genetics | Oncology, Experimental | Colorectal cancer | Antibodies | Metastasis | Research | Antineoplastic agents | Viral antibodies | Antimitotic agents | Consortia | Chemotherapy | Analysis | Genetic research | Genetic aspects | Cancer | Index Medicus
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3. Full Text 70-Gene Signature as an Aid to Treatment Decisions in Early-Stage Breast Cancer
by Cardoso, Fatima and van’t Veer, Laura J and Bogaerts, Jan and Slaets, Leen and Viale, Giuseppe and Delaloge, Suzette and Pierga, Jean-Yves and Brain, Etienne and Causeret, Sylvain and DeLorenzi, Mauro and Glas, Annuska M and Golfinopoulos, Vassilis and Goulioti, Theodora and Knox, Susan and Matos, Erika and Meulemans, Bart and Neijenhuis, Peter A and Nitz, Ulrike and Passalacqua, Rodolfo and Ravdin, Peter and Rubio, Isabel T and Saghatchian, Mahasti and Smilde, Tineke J and Sotiriou, Christos and Stork, Lisette and Straehle, Carolyn and Thomas, Geraldine and Thompson, Alastair M and van der Hoeven, Jacobus M and Vuylsteke, Peter and Bernards, René and Tryfonidis, Konstantinos and Rutgers, Emiel and Piccart, Martine and MINDACT Investigators
The New England journal of medicine, ISSN 0028-4793, 08/2016, Volume 375, Issue 8, pp. 717 - 729
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Breast Neoplasms - surgery | Gene Expression | Genetic Predisposition to Disease | Genetic Testing | Prospective Studies | Oligonucleotide Array Sequence Analysis | Risk Assessment | Humans | Middle Aged | Kaplan-Meier Estimate | Risk | Antineoplastic Agents - therapeutic use | Gene Expression Profiling | Breast Neoplasms - drug therapy | Disease-Free Survival | Breast Neoplasms - genetics | Neoplasm Metastasis - prevention & control | Mastectomy | Adult | Breast Neoplasms - mortality | Female | Aged | Chemotherapy, Adjuvant | Neoplasm Staging | Decision-making | Care and treatment | Breast cancer | Research | Genes | Analysis | Chemotherapy | Epidermal growth factor | Womens health | Endocrine therapy | Genetic testing | Gene expression | Patients | Cancer therapies | Survival | Clinical outcomes | Metastases | Index Medicus | Abridged Index Medicus
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4. Full Text The consensus molecular subtypes of colorectal cancer
by Guinney, Justin and Dienstmann, Roigo and Wang, Xin and de Reyniès, Aurélien and Schlicker, Aneas and Soneson, Charlotte and Marisa, Laetitia and Roepman, Paul and Nyamundanda, Gift and Angelino, Paolo and Bot, Brian M and Morris, Jeffrey S and Simon, Iris M and Gerster, Sarah and Fessler, Evelyn and de Sousa E Melo, Felipe and Missiaglia, Edoardo and Ramay, Hena and Barras, David and Homicsko, Krisztian and Maru, Dipen and Manyam, Ganiraju C and Broom, Bradley and Boige, Valerie and Perez-Villamil, Beatriz and Laderas, Ted and Salazar, Ramon and Gray, Joe W and Hanahan, Douglas and Tabernero, Josep and Bernards, Rene and Friend, Stephen H and Laurent-Puig, Pierre and Medema, Jan Paul and Sadanandam, Anguraj and Wessels, Lodewyk and Delorenzi, Mauro and Kopetz, Scott and Vermeulen, Louis and Tejpar, Sabine
Nature medicine, ISSN 1078-8956, 2015, Volume 21, Issue 11, pp. 1350 - 1356
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | ras Proteins - genetics | Microsatellite Instability | Proto-Oncogene Proteins p21(ras) | Colorectal Neoplasms - genetics | Humans | Gene Expression Regulation, Neoplastic | Gene Expression Profiling | Information Dissemination | Neovascularization, Pathologic - pathology | DNA Methylation | Carcinoma - pathology | Proto-Oncogene Proteins - genetics | Colorectal Neoplasms - classification | DNA Copy Number Variations - genetics | Mutation - genetics | Consensus | Phenotype | Transforming Growth Factor beta - genetics | Wnt Signaling Pathway - genetics | Proto-Oncogene Proteins B-raf - genetics | Genes, myc - genetics | CpG Islands | Carcinoma - genetics | Neovascularization, Pathologic - genetics | Carcinoma - classification | Colorectal Neoplasms - pathology | Care and treatment | Usage | MicroRNA | Colorectal cancer | Liquid chromatography | Research | Gene expression | Transforming growth factors | Genotype & phenotype | Genomics | Index Medicus | Classificació de tumors | Oncologia | Oncology | Càncer colorectal | Tumors classification
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5. Full Text Gene expression patterns unveil a new level of molecular heterogeneity in colorectal cancer
by Budinska, Eva and Popovici, Vlad and Tejpar, Sabine and D'Ario, Giovanni and Lapique, Nicolas and Sikora, Katarzyna Otylia and Di Narzo, Antonio Fabio and Yan, Pu and Hodgson, John Graeme and Weinrich, Scott and Bosman, Fred and Roth, Arnaud and Delorenzi, Mauro
The Journal of pathology, ISSN 0022-3417, 09/2013, Volume 231, Issue 1, pp. 63 - 76
histopathology | colorectal cancer | gene expression | molecular heterogeneity | Histopathology | Molecular heterogeneity | Gene expression | Colorectal cancer | Pathology | Oncology | Life Sciences & Biomedicine | Science & Technology | Colorectal Neoplasms - mortality | Adenocarcinoma - pathology | Prognosis | Oligonucleotide Array Sequence Analysis | Colorectal Neoplasms - genetics | Humans | Kaplan-Meier Estimate | Gene Expression Profiling - methods | Male | Gene Dosage | Loss of Heterozygosity | Genetic Heterogeneity | Female | Adenocarcinoma - genetics | Mutation | Colorectal Neoplasms - pathology | Neoplasm Proteins - genetics | Gene Expression Regulation, Neoplastic - physiology | Adenocarcinoma - mortality | Genetic aspects | Cancer | Index Medicus | Original Papers
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6. Full Text TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection
by Alfei, Francesca and Kanev, Kristiyan and Hofmann, Maike and Wu, Ming and Ghoneim, Hazem E and Roelli, Patrick and Utzschneider, Daniel T and von Hoesslin, Madlaina and Cullen, Jolie G and Fan, Yiping and Eisenberg, Vasyl and Wohlleber, Dirk and Steiger, Katja and Merkler, Doron and Delorenzi, Mauro and Knolle, Percy A and Cohen, Cyrille J and Thimme, Robert and Youngblood, Benjamin and Zehn, Dietmar
Nature (London), ISSN 0028-0836, 07/2019, Volume 571, Issue 7764, pp. 265 - 269
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Lymphocytic choriomeningitis virus - immunology | CD8-Positive T-Lymphocytes - pathology | Cell Proliferation | Hepacivirus - immunology | Epigenesis, Genetic | Homeodomain Proteins - metabolism | Humans | Hepatitis C, Chronic - virology | Male | Hepatocyte Nuclear Factor 1-alpha - metabolism | Lymphocytic Choriomeningitis - immunology | Female | Transcription, Genetic | Cytokines - immunology | Lymphocytic Choriomeningitis - virology | Cytokines - metabolism | High Mobility Group Proteins - metabolism | Gene Expression Regulation - immunology | Thymocytes - immunology | Phenotype | Animals | Hepatitis C, Chronic - immunology | Immunologic Memory | Thymocytes - cytology | Mice | CD8-Positive T-Lymphocytes - immunology | Chronic Disease | Virus diseases | Physiological aspects | Genetic aspects | T cells | PD-1 protein | CD8 antigen | Gene regulation | Chronic infection | Effector cells | Cytotoxicity | Viruses | Lymphocytes T | Genomes | mRNA | Infections | Immunity | Skin cancer | Proteins | T-cell receptor | Hepatitis | Genotype & phenotype | Receptors | Clonal deletion | Lymphocytes | Immunotherapy | DNA methylation | Hepatocyte nuclear factor 1 | Bioinformatics | Deoxyribonucleic acid--DNA | Antigens | Phenotypes | Cytokines | Cloning | Melanoma | T cell receptors | Gene expression | High mobility group proteins | Molecular modelling | Cell death | Exhaustion | Hepatitis C virus | Hepatitis C | Viral infections | Tumors | Index Medicus
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7. Full Text Biological Processes Associated with Breast Cancer Clinical Outcome Depend on the Molecular Subtypes
by Christine Desmedt and Benjamin Haibe-Kains and Pratyaksha Wirapati and Marc Buyse and Denis Larsimont and Gianluca Bontempi and Mauro Delorenzi and Martine Piccart and Christos Sotiriou
Clinical cancer research, ISSN 1078-0432, 08/2008, Volume 14, Issue 16, pp. 5158 - 5165
molecular subtypes | Breast cancer | gene expression profiling | prognosis | modules | Life Sciences & Biomedicine | Oncology | Science & Technology | Gynecology. Andrology. Obstetrics | Mammary gland diseases | Pharmacology. Drug treatments | Biological and medical sciences | Medical sciences | Antineoplastic agents | Tumors | Gene Expression | Breast Neoplasms - genetics | Prognosis | Breast Neoplasms - pathology | Humans | Kaplan-Meier Estimate | Receptors, Estrogen - biosynthesis | Female | Receptor, ErbB-2 | Breast Neoplasms - metabolism | Index Medicus
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8. Full Text Prognostic Role of KRAS and BRAF in Stage II and III Resected Colon Cancer: Results of the Translational Study on the PETACC-3, EORTC 40993, SAKK 60-00 Trial
by Arnaud D. Roth and Sabine Tejpar and Mauro Delorenzi and Pu Yan and Roberto Fiocca and Dirk Klingbiel and Daniel Dietrich and Bart Biesmans and György Bodoky and Carlo Barone and Enrique Aranda and Bernard Nordlinger and Laura Cisar and Roberto Labianca and David Cunningham and Eric Van Cutsem and Fred Bosman
Journal of clinical oncology, ISSN 0732-183X, 01/2010, Volume 28, Issue 3, pp. 466 - 474
Life Sciences & Biomedicine | Oncology | Science & Technology | Gastroenterology. Liver. Pancreas. Abdomen | Stomach. Duodenum. Small intestine. Colon. Rectum. Anus | Biological and medical sciences | Medical sciences | Tumors | ras Proteins - genetics | Colonic Neoplasms - genetics | Proto-Oncogene Proteins p21(ras) | Adenocarcinoma - pathology | Prognosis | Prospective Studies | Humans | Middle Aged | Colonic Neoplasms - diagnosis | Male | Proto-Oncogene Proteins - genetics | Young Adult | Adenocarcinoma - diagnosis | Proto-Oncogene Proteins B-raf - genetics | Colonic Neoplasms - pathology | Adolescent | Adult | Female | Adenocarcinoma - genetics | Aged | Mutation | Index Medicus
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