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Proceedings of the National Academy of Sciences, ISSN 0027-8424, 10/2013, Volume 110, Issue 42, pp. E4016 - E4025
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2015, Volume 10, Issue 11, p. e0142838
Journal Article
Cell Reports, ISSN 2211-1247, 10/2019, Volume 29, Issue 4, pp. 920 - 931.e7
Parkinson’s disease (PD) is characterized by the death of dopamine neurons in the substantia nigra pars compacta (SNc) and accumulation of α-synuclein.... 
mouse models | autophagy | pathology | neurotransmission | behavior | dopamine | Parkinson’s disease | LRRK2 | DISEASE | ALPHA-SYNUCLEIN | AUTOPHAGY | RELEASE | DEFICITS | SUBSTANTIA-NIGRA | MICE LACKING | DEGENERATION | CELL BIOLOGY
Journal Article
International Journal of Neuropsychopharmacology, ISSN 1461-1457, 03/2014, Volume 17, Issue 8, pp. 1295 - 1306
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2008, Volume 105, Issue 41, pp. 15991 - 15996
Acetylcholine (ACh) is a known modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic ACh receptors (nAChRs). Yet,... 
Cholinergics | Locomotion | Neurons | Hyperactivity | Mice | Gene expression regulation | Nicotinic receptors | Cholinergic receptors | Behavioral neuroscience | Ventral tegmental area | Dopaminergic systems | Lentiviral vector | RNAi | Gene rescue | Biological Sciences | gene rescue | lentiviral vector | dopaminergic systems
Journal Article
Current Neuropharmacology, ISSN 1570-159X, 2014, Volume 12, Issue 1, pp. 13 - 14
Journal Article
Neuropharmacology, ISSN 0028-3908, 2017, Volume 113, Part A, pp. 519 - 532
Parkinson's disease (PD) is a progressive neurodegenerative disease originating from the loss of dopa-mine (DA) neurons in the substantia nigra pars compacta... 
Life Sciences | Neurons and Cognition | Neurobiology
Journal Article
Journal Article
FASEB Journal, ISSN 0892-6638, 04/2012, Volume 26, Issue 4, pp. 1682 - 1693
Metabotropic glutamate (mGlu) receptors are promising targets to treat numerous brain disorders. So far, allosteric modulators are the only subtype selective... 
Drug development | mGluR | Parkinson's disease | POSITIVE ALLOSTERIC MODULATION | SITE | ACTIVATION | ACID | RECOGNITION | DOCKING | BIOCHEMISTRY & MOLECULAR BIOLOGY | drug development | BINDING DOMAIN | MOLECULAR DETERMINANTS | CELL BIOLOGY | MGLUR4 | BIOLOGY | CHARMM | Antiparkinson Agents - pharmacology | Rats, Wistar | Humans | Male | Structure-Activity Relationship | Dose-Response Relationship, Drug | Receptors, Metabotropic Glutamate - genetics | HEK293 Cells | Antiparkinson Agents - chemistry | Synaptic Transmission - drug effects | Molecular Structure | Receptors, Metabotropic Glutamate - chemistry | Binding Sites | Recombinant Proteins - metabolism | Excitatory Amino Acid Agonists - metabolism | Mutagenesis, Site-Directed | Phosphinic Acids - chemistry | Rats | Excitatory Amino Acid Agonists - pharmacology | Recombinant Proteins - genetics | Mice, Knockout | Patch-Clamp Techniques | Animals | Phosphinic Acids - pharmacology | Phosphinic Acids - metabolism | Ligands | Mice | Receptors, Metabotropic Glutamate - agonists | Antiparkinson Agents - metabolism | Excitatory Amino Acid Agonists - chemistry | Excitatory Amino Acid Agonists | Neurons and Cognition | Neurobiology | Recombinant Proteins | Synaptic Transmission | Life Sciences | Phosphinic Acids | Psychology and behavior | Antiparkinson Agents | Receptors, Metabotropic Glutamate | Cognitive Sciences
Journal Article
The International Journal of Neuropsychopharmacology, ISSN 1461-1457, 8/2009, Volume 12, Issue 7, pp. 905 - 915
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 03/2016, Volume 25, Issue 5, pp. 951 - 963
Journal Article
The International Journal of Neuropsychopharmacology, ISSN 1461-1457, 2/2008, Volume 11, Issue 1, pp. 79 - 92
Journal Article
Neuropharmacology, ISSN 0028-3908, 09/2011, Volume 61, Issue 3, pp. 478 - 488
Selective serotonin (5-HT) re-uptake inhibitors (SSRIs) are commonly used in the treatment of generalized anxiety disorder in Humans. However, because only few... 
Neurochemistry | SSRI | Paroxetine | KO mice | 5-HT1B receptor | Electrophysiology | Depression | Anxiety | Behavior | 5-HT1A receptor | receptor | 5-HT | IN-VIVO MICRODIALYSIS | GENERALIZED ANXIETY DISORDER | FRONTAL-CORTEX | NEUROSCIENCES | CHRONIC FLUOXETINE | SEROTONIN REUPTAKE INHIBITORS | RECEPTOR KNOCKOUT MICE | PHARMACOLOGY & PHARMACY | DORSAL RAPHE NUCLEUS | OUT MICE | STRESS-INDUCED HYPERTHERMIA
Journal Article