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PLoS ONE, ISSN 1932-6203, 01/2013, Volume 8, Issue 1, p. e55502
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2013, Volume 8, Issue 7, p. e67686
MicroRNAs (miRNAs) are small, non-coding RNAs that regulate gene expression by targeted repression of transcription and translation. In this study we show that... 
METASTASIS | MODEL | MESENCHYMAL TRANSITION | MULTIDISCIPLINARY SCIENCES | Carcinoma, Transitional Cell - mortality | Cell Proliferation | Luciferases - metabolism | Urinary Bladder Neoplasms - diagnosis | Homeodomain Proteins - metabolism | Humans | Gene Expression Regulation, Neoplastic | MicroRNAs - metabolism | Urinary Bladder - pathology | Epithelial-Mesenchymal Transition - genetics | Luciferases - genetics | Urinary Bladder Neoplasms - genetics | Urinary Bladder Neoplasms - pathology | Biomarkers, Tumor - metabolism | Cell Cycle Checkpoints - genetics | Real-Time Polymerase Chain Reaction | Genes, Reporter | Carcinoma, Transitional Cell - genetics | Urinary Bladder Neoplasms - mortality | Signal Transduction | Urinary Bladder - metabolism | Carcinoma, Transitional Cell - diagnosis | Kaplan-Meier Estimate | Transcription Factors - genetics | Homeodomain Proteins - genetics | Transcription Factors - metabolism | Carcinoma, Transitional Cell - pathology | Cell Line, Tumor | Protein Binding | Biomarkers, Tumor - genetics | MicroRNAs - genetics | Cell Movement | Zinc Finger E-box-Binding Homeobox 1 | MicroRNA | Physiological aspects | Development and progression | Tumor suppressor genes | Genetic aspects | Research | Bladder cancer | Cell proliferation | Flow cytometry | Mesenchyme | Veterans | Bladder | Fluorescence | Metastasis | Kinases | Tissues | Medical diagnosis | Urology | Urinary bladder | Cell cycle | Bioindicators | Inhibition | MiRNA | Tumor cell lines | Gene expression | Ribonucleic acid--RNA | Gene silencing | Overexpression | MicroRNAs | Medical prognosis | Cell lines | Biomarkers | Diagnostic systems | Prostate cancer | Cell migration | Cancer | Apoptosis | Tumors | RNA | Ribonucleic acid
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2012, Volume 7, Issue 1, p. e29722
MicroRNA-34a (miR-34a), a potent mediator of tumor suppressor p53, has been reported to function as a tumor suppressor and miR-34a was found to be... 
RECRUITS P-TEFB | CAD PROMOTER | MULTIDISCIPLINARY SCIENCES | HEPATOCYTE GROWTH-FACTOR | IN-VIVO | GENE-EXPRESSION | DOWN-REGULATION | TUMOR-SUPPRESSOR | RHO-GTPASES | MET RECEPTOR | DNA-REPLICATION | Proto-Oncogene Proteins c-met - metabolism | Prostatic Neoplasms - pathology | Cell Proliferation | Neoplasm Invasiveness | Down-Regulation | Humans | Male | MicroRNAs - metabolism | rhoA GTP-Binding Protein - metabolism | Positive Transcriptional Elongation Factor B - metabolism | Proto-Oncogene Proteins c-myc - metabolism | Cell Movement - genetics | Animals | Cell Line, Tumor | Female | Mice | MicroRNAs - genetics | Transcription, Genetic - genetics | Infection | MicroRNA | Luciferase | Cancer cells | Genetic aspects | Genetic transcription | Tumor proteins | Prostate cancer | Apoptosis | Cell proliferation | Transcription elongation | Veterans | p53 Protein | Leukemia | Gene regulation | Xenotransplantation | c-Myc protein | Malignancy | Myc protein | Kinases | Urology | Liver cancer | Cell growth | Transfection | Animal tissues | Cell cycle | Xenografts | Fibroblasts | Inhibition | Elongation | Deoxyribonucleic acid--DNA | MiRNA | Melanoma | RhoA protein | RNA polymerase | Gene expression | Ribonucleic acid--RNA | 3' Untranslated regions | MicroRNAs | Tumor suppressor genes | Prostate | Cell migration | Cancer | RNA | Deoxyribonucleic acid | Ribonucleic acid | DNA
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2013, Volume 8, Issue 3, p. e58929
Genistein has been shown to inhibit cancers both in vitro and in vivo, by altering the expression of several microRNAs (miRNAs). In this study, we focused on... 
GROWTH-FACTOR RECEPTOR | INVASION | METASTASIS | INDUCED APOPTOSIS | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | TARGETING EGFR | MATRIX-METALLOPROTEINASE TYPE-2 | INHIBITS CELL-PROLIFERATION | ENRICHMENT ANALYSIS | PROGRESSION | Cell Proliferation | Apoptosis - drug effects | Humans | Middle Aged | Apoptosis - genetics | Male | Cell Movement - genetics | Neoplasm Grading | Prostatic Neoplasms - genetics | RNA Interference | Base Sequence | Aged, 80 and over | Antineoplastic Agents - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | 3' Untranslated Regions | Binding Sites | Genes, Tumor Suppressor | Prostatic Neoplasms - pathology | Neoplasm Invasiveness | Cell Movement - drug effects | Animals | Base Pairing | Genistein - pharmacology | Aged | Mice | MicroRNAs - genetics | Neoplasm Staging | DNA microarrays | MicroRNA | Genes | Luciferase | Cellular signal transduction | Angiogenesis inhibitors | Comparative analysis | Prostate cancer | Isoflavones | Tumors | Cell proliferation | Biotechnology | Wnt protein | Veterans | Lung cancer | Genistein | mRNA | Kinases | Tissues | Caspase-3 | Cancer therapies | Urology | Angiogenesis | Signal transduction | Cell growth | Epidermal growth factor | Pathways | Bcl-x protein | Restoration | Rodents | Epidermal growth factor receptors | MiRNA | Caspase | Rac1 protein | Gene expression | Real time | Ribonucleic acid--RNA | Bladder cancer | Studies | Polymerase chain reaction | Signaling | Androgens | 3' Untranslated regions | MicroRNAs | Cell lines | Caspase-9 | Tumor suppressor genes | In vivo methods and tests | Prostate | Cell migration | Apoptosis | Cancer | RNA | Ribonucleic acid
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2012, Volume 7, Issue 2, p. e31060
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2012, Volume 7, Issue 11, p. e50203
Background: miR-23b is located on chromosome number 9 and plays different roles in different organs especially with regards to cancer development. However, the... 
CELLS | PROTEIN | PATHWAY | MULTIDISCIPLINARY SCIENCES | KINASE | MYOFIBROBLASTS | MICRORNAS | GENISTEIN | CARCINOMA | PROGRESSION | BREAST | Cell Cycle - genetics | PTEN Phosphohydrolase - genetics | Kidney Neoplasms - genetics | Humans | Gene Expression Regulation, Neoplastic | Carcinoma, Renal Cell - genetics | PTEN Phosphohydrolase - metabolism | Apoptosis - genetics | MicroRNAs - metabolism | Kidney Neoplasms - metabolism | Kidney Neoplasms - mortality | Cell Movement - genetics | Carcinoma, Renal Cell - metabolism | Carcinoma, Renal Cell - mortality | RNA Interference | Genistein - metabolism | Base Sequence | Cell Line, Tumor | MicroRNAs - genetics | Immunohistochemistry | Chemotherapy | Genes | Development and progression | Genetic aspects | Gene expression | Cancer | Biotechnology | Transcription factors | Veterans | Genistein | Chromosome number | AKT protein | Kinases | Tissues | Urology | Proteins | Signal transduction | Human papillomavirus | Rodents | Measurement methods | Inhibition | Cytokines | Invasiveness | Organs | MiRNA | Breast cancer | Chromosome 3 | Ribonucleic acid--RNA | Patients | 1-Phosphatidylinositol 3-kinase | Diet | 3' Untranslated regions | MicroRNAs | Kidney cancer | Cell lines | Tumor suppressor genes | Protein expression | Prostate cancer | PTEN protein | Clear cell-type renal cell carcinoma | Apoptosis | Kidney transplantation | RNA | Ribonucleic acid
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2012, Volume 7, Issue 8, p. e43812
Genistein has been shown to suppress the growth of several cancers through modulation of various pathways. However, the effects of genistein on the regulation... 
JAPANESE MEN | ISOFLAVONES | CELLS | INVASION | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | RISK | CHROMOSOMAL-ABERRATIONS | CARCINOMA | CONSUMPTION | FAMILY | MicroRNAs - antagonists & inhibitors | Humans | Middle Aged | 3' Untranslated Regions - genetics | Male | Cell Movement - genetics | Gene Knockdown Techniques | Luciferases - genetics | Neoplasm Metastasis | Prostatic Neoplasms - genetics | Base Sequence | Antineoplastic Agents - pharmacology | Oncogenes - genetics | Prostatic Neoplasms - pathology | Neoplasm Invasiveness | Computational Biology | Genes, Reporter - genetics | Disease Progression | Genetic Vectors - genetics | Up-Regulation - drug effects | Cell Movement - drug effects | Genistein - pharmacology | Cell Line, Tumor | Aged | Cell Proliferation - drug effects | MicroRNAs - genetics | Care and treatment | MicroRNA | Luciferase | Development and progression | Dosage and administration | Angiogenesis inhibitors | Research | Health aspects | Prostate cancer | Isoflavones | Veterans | Genes | Genistein | Metastasis | Urology | Metastases | Cell adhesion & migration | Rank tests | Proteins | Cell cycle | Interleukin 1 | Inhibition | MiRNA | Gene expression | Real time | Ribonucleic acid--RNA | Bladder cancer | Polymerase chain reaction | Androgens | Diet | 3' Untranslated regions | MicroRNAs | Epigenetics | Prostate | Cell migration | Cancer | RNA | Ribonucleic acid
Journal Article
Cell Death and Differentiation, ISSN 1350-9047, 07/2017, Volume 24, Issue 7, pp. 1263 - 1274
The most frequent alteration in the prostate oncogenome is loss of chromosome (chr) 8p21 that has been associated with loss of NKX3.1 homeobox gene. Chr8p21... 
METASTASIS | TUMOR PROGRESSION | INTEGRATIVE ANALYSIS | CHROMOSOME 8P12-21 | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOWN-REGULATION | HIGH-FREQUENCY | ALLELIC LOSS | E-CADHERIN | MIR-200 FAMILY | REPRESSORS ZEB1 | CELL BIOLOGY | Chromosomes, Human, Pair 8 - genetics | Epithelial Cells - metabolism | Prognosis | Homeodomain Proteins - metabolism | Humans | Gene Expression Regulation, Neoplastic | Male | MicroRNAs - metabolism | Epithelial-Mesenchymal Transition - genetics | Neoplasm Proteins - metabolism | Promoter Regions, Genetic - genetics | Gene Knockdown Techniques | Prostatic Neoplasms - genetics | Cell Transformation, Neoplastic - genetics | Base Sequence | Prostatic Neoplasms - pathology | Cell Proliferation - genetics | Neoplasm Invasiveness | Epithelial Cells - pathology | DNA Methylation - genetics | Disease Progression | Transcription Factors - metabolism | Animals | Mice, Nude | Cell Line, Tumor | MicroRNAs - genetics | Cell Transformation, Neoplastic - pathology | Genome, Human | Biotechnology | Profiling | Mesenchyme | MiRNA | In vitro testing | Metastasis | Nkx3.1 protein | Carcinogenesis | Suppressors | Metastases | Homeobox | Carcinogens | Ribonucleic acids | Medical prognosis | MicroRNAs | Effectors | Cell lines | Biomarkers | Snail protein | Prostate | Prostate cancer | Cancer | Index Medicus | Original Paper
Journal Article
Journal Article