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Nature, ISSN 0028-0836, 01/2017, Volume 541, Issue 7637, pp. 359 - 364
Journal Article
Cancer Research, ISSN 0008-5472, 11/2015, Volume 75, Issue 22 Supplement 2, pp. B2 - B2-57
Journal Article
Cancer Research, ISSN 0008-5472, 11/2015, Volume 75, Issue 22 Supplement 1, pp. A1 - A1-17
Journal Article
Nature, ISSN 0028-0836, 2016, Volume 538, Issue 7625, pp. 378 - 382
Journal Article
by Biankin, Andrew V and Waddell, Nicola and Kassahn, Karin S and Gingras, Marie-Claude and Muthuswamy, Lakshmi B and Johns, Amber L and Miller, David K and Wilson, Peter J and Patch, Ann-Marie and Wu, Jianmin and Chang, David K and Cowley, Mark J and Gardiner, Brooke B and Song, Sarah and Harliwong, Ivon and Idrisoglu, Senel and Nourse, Craig and Nourbakhsh, Ehsan and Manning, Suzanne and Wani, Shivangi and Gongora, Milena and Pajic, Marina and Scarlett, Christopher J and Gill, Anthony J and Pinho, Andreia V and Rooman, Ilse and Anderson, Matthew and Holmes, Oliver and Leonard, Conrad and Taylor, Darrin and Wood, Scott and Xu, Qinying and Nones, Katia and Fink, J. Lynn and Christ, Angelika and Bruxner, Tim and Cloonan, Nicole and Kolle, Gabriel and Newell, Felicity and Pinese, Mark and Mead, R. Scott and Humphris, Jeremy L and Kaplan, Warren and Jones, Marc D and Colvin, Emily K and Nagrial, Adnan M and Humphrey, Emily S and Chou, Angela and Chin, Venessa T and Chantrill, Lorraine A and Mawson, Amanda and Samra, Jaswinder S and Kench, James G and Lovell, Jessica A and Daly, Roger J and Merrett, Neil D and Toon, Christopher and Epari, Krishna and Nguyen, Nam Q and Barbour, Andrew and Zeps, Nikolajs and Kakkar, Nipun and Zhao, Fengmei and Wu, Yuan Qing and Wang, Min and Muzny, Donna M and Fisher, William E and Brunicardi, F. Charles and Hodges, Sally E and Reid, Jeffrey G and Drummond, Jennifer and Chang, Kyle and Han, Yi and Lewis, Lora R and Dinh, Huyen and Buhay, Christian J and Beck, Timothy and Timms, Lee and Sam, Michelle and Begley, Kimberly and Brown, Andrew and Pai, Deepa and Panchal, Ami and Buchner, Nicholas and De Borja, Richard and Denroche, Robert E and Yung, Christina K and Serra, Stefano and Onetto, Nicole and Mukhopadhyay, Debabrata and Tsao, Ming-Sound and Shaw, Patricia A and Petersen, Gloria M and Gallinger, Steven and Hruban, Ralph H and Maitra, Anirban and Iacobuzio-Donahue, Christine A and Schulick, Richard D and Wolfgang, Christopher L and Morgan, Richard A and ... and Australian Pancreatic Canc Genome and Australian Pancreatic Cancer Genome Initiative
Nature, ISSN 0028-0836, 11/2012, Volume 491, Issue 7424, pp. 399 - 405
Journal Article
Nature Genetics, ISSN 1061-4036, 07/2015, Volume 47, Issue 7, pp. 736 - +
Journal Article
by Alioto, Tyler S and Buchhalter, Ivo and Derdak, Sophia and Hutter, Barbara and Eldridge, Matthew D and Hovig, Eivind and Heisler, Lawrence E and Beck, Timothy A and Simpson, Jared T and Tonon, Laurie and Sertier, Anne-Sophie and Patch, Ann-Marie and Jäger, Natalie and Ginsbach, Philip and Drews, Ruben and Paramasivam, Nagarajan and Kabbe, Rolf and Chotewutmontri, Sasithorn and Diessl, Nicolle and Previti, Christopher and Schmidt, Sabine and Brors, Benedikt and Feuerbach, Lars and Heinold, Michael and Gröbner, Susanne and Korshunov, Andrey and Tarpey, Patrick S and Butler, Adam P and Hinton, Jonathan and Jones, David and Menzies, Andrew and Raine, Keiran and Shepherd, Rebecca and Stebbings, Lucy and Teague, Jon W and Ribeca, Paolo and Giner, Francesc Castro and Beltran, Sergi and Raineri, Emanuele and Dabad, Marc and Heath, Simon C and Gut, Marta and Denroche, Robert E and Harding, Nicholas J and Yamaguchi, Takafumi N and Fujimoto, Akihiro and Nakagawa, Hidewaki and Quesada, Víctor and Valdés-Mas, Rafael and Nakken, Sigve and Vodák, Daniel and Bower, Lawrence and Lynch, Andrew G and Anderson, Charlotte L and Waddell, Nicola and Pearson, John V and Grimmond, Sean M and Peto, Myron and Spellman, Paul and He, Minghui and Kandoth, Cyriac and Lee, Semin and Zhang, John and Létourneau, Louis and Ma, Singer and Seth, Sahil and Torrents, David and Xi, Liu and Wheeler, David A and López-Otín, Carlos and Campo, Elías and Campbell, Peter J and Boutros, Paul C and Puente, Xose S and Gerhard, Daniela S and Pfister, Stefan M and McPherson, John D and Hudson, Thomas J and Schlesner, Matthias and Lichter, Peter and Eils, Roland and Jones, David T.W and Gut, Ivo G
Nature Communications, ISSN 2041-1723, 12/2015, Volume 6, Issue 1, p. 10001
As whole-genome sequencing for cancer genome analysis becomes a clinical tool, a full understanding of the variables affecting sequencing analysis output is... 
POINT MUTATIONS | EXOME | ACCURATE | VARIANT ANALYSIS | SIGNATURES | ALIGNMENT | MULTIDISCIPLINARY SCIENCES | FRAMEWORK | Mutation | Genome, Human | High-Throughput Nucleotide Sequencing - methods | Medulloblastoma - genetics | Humans | Leukemia, Lymphoid - genetics | Càncer | Medical genetics | Mutació (Biologia) | Genètica mèdica | Genètica humana | Human genetics | Mutation (Biology) | Cancer
Journal Article
Journal Article
Cancer Discovery, ISSN 2159-8274, 09/2018, Volume 8, Issue 9, pp. 1112 - 1129
Pancreatic cancer is the most lethal common solid malignancy. Systemic therapies are often ineffective, and predictive biomarkers to guide treatment are... 
TRIAL | MULTICENTER | ONCOLOGY | DUCTAL ADENOCARCINOMA | SEQUENCE DATA | SUBTYPES | TUMOR | TRANSLATION | STRUCTURAL VARIATION | PAIRED-END | GEMCITABINE | Pancreatic Cancer | Pharmacotyping | Organoids | Pharmacotranscriptomics | Common Responders | Precision Medicine
Journal Article
International Journal of Cancer, ISSN 0020-7136, 07/2018, Volume 143, Issue 1, pp. 179 - 183
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies. BRCA‐associated PDAC comprises a clinically relevant subtype. A portion of... 
BRCA | treatment resistant | PARP inhibitor | treatment naïve | pancreatic ductal adenocarcinoma | patient‐derived xenograft (PDX) | patient-derived xenograft (PDX) | SURVIVAL | ONCOLOGY | DUCTAL ADENOCARCINOMA | SUBTYPES | RESISTANCE | treatment naive | Genomic Instability | Neoplasm Transplantation | Prognosis | Humans | Drug Resistance, Neoplasm | Homologous Recombination | Pancreatic Neoplasms - genetics | Disease Progression | Poly(ADP-ribose) Polymerase Inhibitors - therapeutic use | Carcinoma, Pancreatic Ductal - genetics | Poly(ADP-ribose) Polymerase Inhibitors - administration & dosage | Whole Genome Sequencing | Pancreatic Neoplasms - drug therapy | Platinum Compounds - therapeutic use | BRCA1 Protein - genetics | Carcinoma, Pancreatic Ductal - drug therapy | Neoplasm Metastasis | Animals | Mice | Mutation | Platinum Compounds - administration & dosage | BRCA2 Protein - genetics | Biotechnology | Pancreatic cancer | Genomics | Therapeutics | Metastasis | Homeopathy | Materia medica and therapeutics | Adenocarcinoma | Sensitivity analysis | Xenotransplantation | Medical treatment | DNA damage | Homologous recombination | Poly(ADP-ribose) polymerase | Homology | Genomes | Breast cancer | Patients | Cisplatin | Mimicry | Metastases | Gene sequencing | Inhibitors | Biopsy | Platinum | Xenografts | Models | Lesions | Deoxyribonucleic acid--DNA | Cancer
Journal Article