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by Jamal-Hanjani, Mariam and Wilson, Gareth A and McGranahan, Nicholas and Birkbak, Nicolai J and Watkins, Thomas B.K and Veeriah, Selvaraju and Shafi, Seema and Johnson, Diana H and Mitter, Richard and Rosenthal, Rachel and Salm, Max and Horswell, Stuart and Escudero, Mickael and Matthews, Nik and Rowan, Andrew and Chambers, Tim and Moore, David A and Turajlic, Samra and Xu, Hang and Lee, Siow-Ming and Forster, Martin D and Ahmad, Tanya and Hiley, Crispin T and Abbosh, Christopher and Falzon, Mary and Borg, Elaine and Marafioti, Teresa and Lawrence, David and Hayward, Martin and Kolvekar, Shyam and Panagiotopoulos, Nikolaos and Janes, Sam M and Thakrar, Ricky and Ahmed, Asia and Blackhall, Fiona and Summers, Yvonne and Shah, Rajesh and Joseph, Leena and Quinn, Anne M and Crosbie, Phil A and Naidu, Babu and Middleton, Gary and Langman, Gerald and Trotter, Simon and Nicolson, Marianne and Remmen, Hardy and Kerr, Keith and Chetty, Mahendran and Gomersall, Lesley and Fennell, Dean A and Nakas, Apostolos and Rathinam, Sridhar and Anand, Girija and Khan, Sajid and Russell, Peter and Ezhil, Veni and Ismail, Babikir and Irvin-Sellers, Melanie and Prakash, Vineet and Lester, Jason F and Kornaszewska, Malgorzata and Attanoos, Richard and Adams, Haydn and Davies, Helen and Dentro, Stefan and Taniere, Philippe and O’Sullivan, Brendan and Lowe, Helen L and Hartley, John A and Iles, Natasha and Bell, Harriet and Ngai, Yenting and Shaw, Jacqui A and Herrero, Javier and Szallasi, Zoltan and Schwarz, Roland F and Stewart, Aengus and Quezada, Sergio A and Le Quesne, John and Van Loo, Peter and Dive, Caroline and Hackshaw, Allan and Swanton, Charles and TRACERx Consortium
The New England Journal of Medicine, ISSN 0028-4793, 06/2017, Volume 376, Issue 22, pp. 2109 - 2121
Journal Article
by Wedge, David C and Gundem, Gunes and Mitchell, Thomas and Woodcock, Dan J and Martincorena, Inigo and Ghori, Mohammed and Zamora, Jorge and Butler, Adam and Whitaker, Hayley and Kote-Jarai, Zsofia and Alexandrov, Ludmil B and Van Loo, Peter and Massie, Charlie E and Dentro, Stefan and Warren, Anne Y and Verrill, Clare and Berney, Dan M and Dennis, Nening and Merson, Sue and Hawkins, Steve and Howat, William and Lu, Yong-Jie and Lambert, Adam and Kay, Jonathan and Kremeyer, Barbara and Karaszi, Katalin and Luxton, Hayley and Camacho, Niedzica and Marsden, Luke and Edwards, Sandra and Matthews, Lucy and Bo, Valeria and Leongamornlert, Daniel and McLaren, Stuart and Ng, Anthony and Yu, Yongwei and Zhang, Hongwei and Dadaev, Tokhir and Thomas, Sarah and Easton, Douglas F and Ahmed, Mahbubl and Bancroft, Elizabeth and Fisher, Cyril and Livni, Naomi and Nicol, David and Tavaré, Simon and Gill, Pelvender and Greenman, Christopher and Khoo, Vincent and Van As, Nicholas and Kumar, Pardeep and Ogden, Christopher and Cahill, Declan and Thompson, Alan and Mayer, Erik and Rowe, Edward and Dudderidge, Tim and Gnanapragasam, Vincent and Shah, Nimish C and Raine, Keiran and Jones, David and Menzies, Andrew and Stebbings, Lucy and Teague, Jon and Hazell, Steven and Corbishley, Cathy and De Bono, Johann and Attard, Gerhardt and Isaacs, William and Visakorpi, Tapio and Fraser, Michael and Boutros, Paul C and Bristow, Robert G and Workman, Paul and Sander, Chris and Hamdy, Freddie C and Futreal, Andrew and McDermott, Ultan and Al-Lazikani, Bissan and Lynch, Andrew G and Bova, G. Steven and Foster, Christopher S and Brewer, Daniel S and Neal, David E and Cooper, Colin S and Eeles, Rosalind A and TCGA Consortium and CAMCAP Study Grp and CAMCAP Study Group and The TCGA Consortium
Nature Genetics, ISSN 1061-4036, 05/2018, Volume 50, Issue 5, pp. 682 - 692
Journal Article
by Abbosh, Christopher and Birkbak, Nicolai J and Wilson, Gareth A and Jamal-Hanjani, Mariam and Constantin, Tudor and Salari, Raheleh and Le Quesne, John and Moore, David A and Veeriah, Selvaraju and Rosenthal, Rachel and Marafioti, Teresa and Kirkizlar, Eser and Watkins, Thomas B. K and McGranahan, Nicholas and Ward, Sophia and Martinson, Luke and Riley, Joan and Fraioli, Francesco and Al Bakir, Maise and Grönroos, Eva and Zambrana, Francisco and Endozo, Raymondo and Bi, Wenya Linda and Fennessy, Fiona M and Sponer, Nicole and Johnson, Diana and Laycock, Joanne and Shafi, Seema and Czyzewska-Khan, Justyna and Rowan, Andrew and Chambers, Tim and Matthews, Nik and Turajlic, Samra and Hiley, Crispin and Lee, Siow Ming and Forster, Martin D and Ahmad, Tanya and Falzon, Mary and Borg, Elaine and Lawrence, David and Hayward, Martin and Kolvekar, Shyam and Panagiotopoulos, Nikolaos and Janes, Sam M and Thakrar, Ricky and Ahmed, Asia and Blackhall, Fiona and Summers, Yvonne and Hafez, Dina and Naik, Ashwini and Ganguly, Apratim and Kareht, Stephanie and Shah, Rajesh and Joseph, Leena and Quinn, Anne Marie and Crosbie, Phil A and Naidu, Babu and Middleton, Gary and Langman, Gerald and Trotter, Simon and Nicolson, Marianne and Remmen, Hardy and Kerr, Keith and Chetty, Mahendran and Gomersall, Lesley and Fennell, Dean A and Nakas, Apostolos and Rathinam, Sridhar and Anand, Girija and Khan, Sajid and Russell, Peter and Ezhil, Veni and Ismail, Babikir and Irvin-Sellers, Melanie and Prakash, Vineet and Lester, Jason F and Kornaszewska, Malgorzata and Attanoos, Richard and Adams, Haydn and Davies, Helen and Oukrif, Dahmane and Akarca, Ayse U and Hartley, John A and Lowe, Helen L and Lock, Sara and Iles, Natasha and Bell, Harriet and Ngai, Yenting and Elgar, Greg and Szallasi, Zoltan and Schwarz, Roland F and Herrero, Javier and Stewart, Aengus and Quezada, Sergio A and Peggs, Karl S and Van Loo, Peter and Dive, Caroline and Lin, C. Jimmy and Rabinowitz, Matthew and Aerts, Hugo J. W. L and ... and TRACERx Consortium and The PEACE Consortium and TRACERx consortium and PEACE consortium and The PEACE consortium and The TRACERx consortium
Nature, ISSN 0028-0836, 04/2017, Volume 545, Issue 7655, pp. 446 - 451
Journal Article
by McGranahan, Nicholas and Rosenthal, Rachel and Hiley, Crispin and Hiley, Crispin T and Rowan, Andrew and Rowan, Andrew J and Watkins, Thomas B.K and Wilson, Gareth and Wilson, Gareth A and Birkbak, Nicolai J and Veeriah, Selvaraju and Van Loo, Peter and Herrero, Javier and Swanton, Charles and Jamal-Hanjani, Mariam and Shafi, Seema and Czyzewska-Khan, Justyna and Johnson, Benjamin and Johnson, Diana and Laycock, Joanne and Bosshard-Carter, Leticia and Gorman, Pat and Hynds, Robert E and Horswell, Stuart and Mitter, Richard and Escudero, Mickael and Stewart, Aengus and Xu, Hang and Turajlic, Samra and Abbosh, Christopher and Goldman, Jacki and Stone, Richard Kevin and Denner, Tamara and Matthews, Nik and Matthews, Sue and Elgar, Greg and Ward, Sophia and Costa, Marta and Begum, Sharmin and Phillimore, Ben and Chambers, Tim and Nye, Emma and Graca, Sofia and Al Bakir, Maise and Joshi, Kroopa and Furness, Andrew and Ben Aissa, Assma and Wong, Yien Ning Sophia and Georgiou, Andy and Quezada, Sergio and Hartley, John A and Lowe, Helen L and Lawrence, David and Hayward, Martin and Panagiotopoulos, Nikolaos and Kolvekar, Shyam and Falzon, Mary and Borg, Elaine and Marafioti, Teresa and Simeon, Celia and Hector, Gemma and Smith, Amy and Smith, Sean and Smith, Elaine and Aranda, Marie and Novelli, Marco and Oukrif, Dahmane and Janes, Sam M and Thakrar, Ricky and Forster, Martin and Ahmad, Tanya and Lee, Siow Ming and Papadatos-Pastos, Dionysis and Carnell, Dawn and Mendes, Ruheena and George, Jeremy and Navani, Neal and Ahmed, Asia and Taylor, Paul and Taylor, Magali and Choudhary, Junaid and Summers, Yvonne and Califano, Raffaele and Shah, Rajesh and Krysiak, Piotr and Rammohan, Kendadai and Fontaine, Eustace and Booton, Richard and Evison, Matthew and Crosbie, Phil and Moss, Stuart and Idries, Faiza and Joseph, Leena and Bishop, Paul and Chaturved, Anshuman and Quinn, Anne Marie and Doran, Helen and Leek, Angela and Harrison, Phil and Moore, Katrina and ... and TRACERx Consortium
Cell, ISSN 0092-8674, 11/2017, Volume 171, Issue 6, pp. 1259 - 1271.e11
Journal Article
Cold Spring Harbor perspectives in medicine, ISSN 2157-1422, 08/2017, Volume 7, Issue 8, p. a026625
Journal Article
by Tarabichi, Maxime and Tarabichi, Maxime and Martincorena, Iñigo and Gerstung, Moritz and Gerstung, Moritz and Leroi, Armand M and Markowetz, Florian and Markowetz, Florian and Dentro, Stefan C and Leshchiner, Ignaty and Spellman, Paul T and Morris, Quaid D and Jolly, Clemency and Lingjærde, Ole Christian and Haase, Kerstin and Wedge, David C and Wintersinger, Jeff and Deshwar, Amit G and Van Loo, Peter and Yu, Kaixian and Gonzalez, Santiago and Rubanova, Yulia and Macintyre, Geoff and Adams, David J and Anur, Pavana and Beroukhim, Rameen and Boutros, Paul C and Bowtell, David D and Campbell, Peter J and Cao, Shaolong and Christie, Elizabeth L and Cmero, Marek and Cun, Yupeng and Dawson, Kevin J and Demeulemeester, Jonas and Donmez, Nilgun and Drews, Ruben M and Eils, Roland and Fan, Yu and Fittall, Matthew and Garsed, Dale W and Getz, Gad and Ha, Gavin and Imielinski, Marcin and Jerman, Lara and Ji, Yuan and Kleinheinz, Kortine and Lee, Juhee and Lee-Six, Henry and Livitz, Dimitri G and Malikic, Salem and Mitchell, Thomas J and Mustonen, Ville and Oesper, Layla and Peifer, Martin and Peto, Myron and Raphael, Benjamin J and Rosebrock, Daniel and Sahinalp, S. Cenk and Salcedo, Adriana and Schlesner, Matthias and Schumacher, Steven and Sengupta, Subhajit and Shi, Ruian and Shin, Seung Jun and Stein, Lincoln D and Vázquez-García, Ignacio and Vembu, Shankar and Wheeler, David A and Yang, Tsun-Po and Yao, Xiaotong and Yuan, Ke and Zhu, Hongtu and Wang, Wenyi and Morris, Quaid D and Spellman, Paul T and Wedge, David C and Van Loo, Peter and Lingjærde, Ole Christian and PCAWG Evolution Heterogeneity and PCAWG Evolution and Heterogeneity Working Group and The PCAWG Evolution and Heterogeneity Working Group
Nature Genetics, ISSN 1061-4036, 12/2018, Volume 50, Issue 12, pp. 1630 - 1633
According to this traditional model, the selective advantage is conferred by a small set of driver mutations, but as the subclones that bear them successively... 
PATTERNS | CLONAL EVOLUTION | CANCER | GENETICS & HEREDITY | Research | Neutral evolution | Oncology, Experimental | Cancer | Genetic drift | Medical research | Computer simulation | Neutrality | Genomes | Gene sequencing | Genetic variance | Simulation | Cell death | Frequency distribution | Drift | Mutation | Charitable foundations | Tumors | Apoptosis
Journal Article