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animals (47) 47
apoptosis (46) 46
neurons (32) 32
mice (30) 30
cell biology (27) 27
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apoptosis - physiology (18) 18
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activation (6) 6
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1. Full Text Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c
by Deshmukh, Mohanish and Vaughn, Allyson E
Nature Cell Biology, ISSN 1465-7392, 12/2008, Volume 10, Issue 12, pp. 1477 - 1483
Neurons and cancer cells use glucose extensively, yet the precise advantage of this adaptation remains unclear. These two seemingly disparate cell types also... 
OXYGEN | SYSTEM | MECHANISM | GLUTATHIONE | STATE | DEATH | RELEASE | CASPASE ACTIVATION | CELL BIOLOGY | Pentose Phosphate Pathway - drug effects | Apoptosis - drug effects | Cytochromes c - metabolism | Humans | Mice, Inbred C57BL | Sympathetic Nervous System - cytology | Nerve Growth Factor - pharmacology | Neurons - cytology | Animals | Cytoprotection - drug effects | Oxidation-Reduction - drug effects | Cell Line, Tumor | Glucose - metabolism | Mice | Neurons - metabolism | Glucose metabolism | Neurons | Cancer cells | Physiological aspects | Genetic aspects | Research | Health aspects | Apoptosis | Cytochrome c | Glycolysis | apoptosis | caspases | Pentose Phosphate Pathway | ROS
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2. Full Text Adenosine: Essential for life but licensed to kill
by Gama, Vivian and Deshmukh, Mohanish
Molecular cell, ISSN 1097-2765, 4/2015, Volume 58, Issue 2, pp. 199 - 201
In this issue of Molecular Cell , Long et al. ( Long et al., 2013 ) report a cell death priming mechanism activated by p53 that senses extracellular adenosine... 
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3. Full Text Apoptotic cell death regulation in neurons
by Hollville, Emilie and Romero, Selena E and Deshmukh, Mohanish
The FEBS Journal, ISSN 1742-464X, 09/2019, Volume 286, Issue 17, pp. 3276 - 3298
Apoptosis plays a major role in shaping the developing nervous system during embryogenesis as neuronal precursors differentiate to become post‐mitotic neurons.... 
Apaf‐1 | JNK | NPCs | neurodegeneration | apoptosis | Bcl‐2 | neuronal maturation | XIAP | neurons | caspase | Neurons | Biochemistry | Apoptosis | Embryonic growth stage | Embryogenesis | Cell survival | Cell death | Functional morphology | Neural stem cells | Nervous system | Survival
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4. Full Text Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
by Galluzzi, Lorenzo and Vitale, Ilio and Aaronson, Stuart A and Abrams, John M and Adam, Dieter and Agostinis, Patrizia and Alnemri, Emad S and Altucci, Lucia and Amelio, Ivano and Anews, David W and Annicchiarico-Petruzzelli, Margherita and Antonov, Alexey V and Arama, Eli and Baehrecke, Eric H and Barlev, Nickolai A and Bazan, Nicolas G and Bernassola, Francesca and Bertrand, Mathieu J. M and Bianchi, Katiuscia and Blagosklonny, Mikhail V and Blomgren, Klas and Borner, Christoph and Boya, Patricia and Brenner, Catherine and Campanella, Michelangelo and Candi, Eleonora and Carmona-Gutierrez, Didac and Cecconi, Francesco and Chan, Francis K.-M and Chandel, Navdeep S and Cheng, Emily H and Chipuk, Jerry E and Cidlowski, John A and Ciechanover, Aaron and Cohen, Gerald M and Conrad, Marcus and Cubillos-Ruiz, Juan R and Czabotar, Peter E and D'Angiolella, Vincenzo and Dawson, Ted M and Dawson, Valina L and de Laurenzi, Vincenzo and de Maria, Ruggero and Debatin, Klaus-Michael and DeBerardinis, Ralph J and Deshmukh, Mohanish and Di Daniele, Nicola and Di Virgilio, Francesco and Dixit, Vishva M and Dixon, Scott J and Duckett, Colin S and Dynlacht, Brian D and El-Deiry, Wafik S and Elrod, John W and Fimia, Gian Maria and Fulda, Simone and García-Sáez, Ana J and Garg, Abhishek D and Garrido, Carmen and Gavathiotis, Evripidis and Golstein, Pierre and Gottlieb, Eyal and Green, Douglas R and Greene, Lloyd A and Gronemeyer, Hinrich and Gross, Atan and Hajnoczky, Gyorgy and Hardwick, J. Marie and Harris, Isaac S and Hengartner, Michael O and Hetz, Claudio and Ichijo, Hidenori and Jäättelä, Marja and Joseph, Bertrand and Jost, Philipp J and Juin, Philippe P and Kaiser, William J and Karin, Michael and Kaufmann, Thomas and Kepp, Oliver and Kimchi, Adi and Kitsis, Richard N and Klionsky, Daniel J and Knight, Richard A and Kumar, Sharad and Lee, Sam W and Lemasters, John J and Levine, Beth and Linkermann, Aneas and Lipton, Stuart A and Lockshin, Richard A and López-Otín, Carlos and Lowe, Scott W and Luedde, Tom and Lugli, Enrico and MacFarlane, Marion and Madeo, Frank and Malewicz, Michal and Malorni, Walter and Manic, Gwenola and ...
Cell death and differentiation, ISSN 1350-9047, 2018, Volume 25, Issue 3, pp. 486 - 541
Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated guidelines for the definition and interpretation of cell death from... 
BCL-2 FAMILY-MEMBER | MITOCHONDRIAL PERMEABILITY TRANSITION | TUMOR-NECROSIS-FACTOR | NEUTROPHIL EXTRACELLULAR TRAPS | LYSOSOMAL MEMBRANE PERMEABILIZATION | GLUTATHIONE-PEROXIDASE 4 | BIOCHEMISTRY & MOLECULAR BIOLOGY | MIXED LINEAGE KINASE | NONCANONICAL INFLAMMASOME ACTIVATION | CYTOCHROME-C RELEASE | NF-KAPPA-B | CELL BIOLOGY | Mitochondrial Membrane Transport Proteins - metabolism | Animals | Lysosomes - metabolism | Humans | Cell Death | Lysosomes - pathology | Necrosis - metabolism | Necrosis - pathology | Mitochondria | Senescence | Molecular modelling | Immunogenicity | Cell death | Nomenclature | Mitochondrial DNA | Permeability | Autophagy | Phagocytosis | Apoptosis | Life Sciences | Cancer | Review
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5. Full Text Distinct pathways mediate axon degeneration during apoptosis and axon-specific pruning
by Cusack, Corey L and Swahari, Vijay and Hampton Henley, W and Michael Ramsey, J and Deshmukh, Mohanish
Nature Communications, ISSN 2041-1723, 2013, Volume 4, Issue 1, pp. 1876 - 1876
Neurons can activate pathways that destroy the whole cell via apoptosis or selectively degenerate only the axon (pruning). Both apoptosis and axon degeneration... 
SYSTEM | ACTIVATION | SELF-DESTRUCTION | MULTIDISCIPLINARY SCIENCES | WALLERIAN DEGENERATION | CASPASES | PROTEASOME | DISEASE | SYMPATHETIC NEURONS | DEATH | NERVE GROWTH-FACTOR | Nerve Degeneration - enzymology | Cytochromes c - secretion | Apoptosis - drug effects | Mice, Inbred C57BL | Axons - drug effects | Axons - metabolism | Axons - secretion | Enzyme Activation - drug effects | Nerve Degeneration - metabolism | Nerve Degeneration - pathology | Apoptotic Protease-Activating Factor 1 - metabolism | Nerve Growth Factors - pharmacology | Animals | Caspases - metabolism | Signal Transduction - drug effects | Models, Biological | Axons - pathology | X-Linked Inhibitor of Apoptosis Protein - metabolism | Mice | Proteasome Endopeptidase Complex - metabolism | Aging - metabolism
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