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1. Full Text Role of boundary conditions in determining cell alignment in response to stretch
by Deshpande, Vikram Sudhir
ISSN 0027-8424, 2018
he ability of cells to orient in response to mechanical stimuli is essential to embryonic development, cell migration, mechanotrans- duction, and other... 
fibroblast orientation | computational modeling | cytoskeleton | cell mechanics | stress fibers
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2. Full Text The homeostatic ensemble for cells
by Deshpande, Vikram Sudhir
ISSN 1617-7959, 2018
Cells are quintessential examples of out of equilibrium systems but they maintain a homeostatic state over a timescale of hours to days. As a consequence, the... 
Cytoskeleton | Fluctuations | Statistical mechanics | Cell | Effective temperature
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3. Full Text The diagnostic utility of serum IgG4 concentrations in IgG4-related disease
by Carruthers, Mollie N and Khosroshahi, Arezou and Augustin, Tamara and Deshpande, Vikram and Stone, John H
Annals of the Rheumatic Diseases, ISSN 0003-4967, 03/2014, Volume 74, Issue 1, pp. 14 - 18
Objectives We evaluated the sensitivity, specificity and positive and negative predictive values of elevated serum IgG4 concentrations for the diagnosis of... 
AUTOIMMUNE PANCREATITIS | RHEUMATOLOGY | Predictive Value of Tests | Immunoglobulin G - blood | Humans | Middle Aged | Autoimmune Diseases - immunology | Male | Autoimmune Diseases - diagnosis | Autoimmune Diseases - blood | Immunoglobulin G - immunology | Sensitivity and Specificity | Adult | Female | Aged | Retrospective Studies | Cohort Studies | Serum | Immunologic diseases | Diagnosis | Immunoglobulin G | Analysis | Risk factors | Studies | Pneumonia | Hospitals | Disease | Womens health | Biopsy | Medical laboratories | Gender differences | Females | Patients | Binding sites | Index Medicus
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4. Full Text Design and formulation of functional pluripotent stem cell-derived cardiac microtissues
by Nimalan Thavandiran and Nicole Dubois and Alexander Mikryukov and Stéphane Massé and Bogdan Beca and Craig A. Simmons and Vikram S. Deshpande and J. Patrick McGarry and Christopher S. Chen and Kumaraswamy Nanthakumar and Gordon M. Keller and Milica Radisic and Peter W. Zandstra
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 12/2013, Volume 110, Issue 49, pp. E4698 - E4707
Access to robust and information-rich human cardiac tissue models would accelerate drug-based strategies for treating heart disease. Despite significant... 
Heart regeneration | Arrhythmia disease model | Microfabrication | Tissue engineering | Cardiac toxicity | tissue engineering | CONTRACTILITY | MULTIDISCIPLINARY SCIENCES | TISSUE | CARDIOMYOCYTES | MODEL | SIMULATION | HEART | cardiac toxicity | heart regeneration | arrhythmia disease model | RESISTANCE | microfabrication | ACTIN CYTOSKELETON | STRESS-FIBER | DIFFERENTIATION | Thy-1 Antigens - metabolism | Transcription Factors - metabolism | Homeobox Protein Nkx-2.5 | Biomechanical Phenomena | Electric Stimulation | Pluripotent Stem Cells - cytology | Tissue Engineering - methods | Homeodomain Proteins - metabolism | Humans | Cellular Microenvironment - physiology | Finite Element Analysis | Myocardium - cytology | Cardiovascular system | Tissue | Collagen | Stem cells | Mechanics | Miniaturization | Gene expression | Index Medicus | Biological Sciences | PNAS Plus
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5. Full Text The one-dimensional Wigner crystal in carbon nanotubes
by Deshpande, Vikram V and Bockrath, Marc
Nature Physics, ISSN 1745-2473, 04/2008, Volume 4, Issue 4, pp. 314 - 318
A dilute system of electrons interacting through long-range Coulomb forces has been predicted to form a periodic solid known as a Wigner crystal. To date, this... 
PHYSICS, MULTIDISCIPLINARY | WIRE | QUANTUM-DOT | Materials science | Crystallography | Carbon | Physics | Nanotubes
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6. Full Text Mechanisms of disease: IgG4-related disease
by Stone, John H and Zen, Yoh and Deshpande, Vikram
New England Journal of Medicine, ISSN 0028-4793, 02/2012, Volume 366, Issue 6, pp. 539 - 551
MEDICINE, GENERAL & INTERNAL | MULTIFOCAL FIBROSCLEROSIS | AUTOIMMUNE PANCREATITIS | SYSTEMIC-DISEASE | RETROPERITONEAL FIBROSIS | REGULATORY T-CELLS | MEMBRANOUS NEPHROPATHY | SERUM IGG4 LEVELS | TUBULOINTERSTITIAL NEPHRITIS | IMMUNOGLOBULIN G4 | MIKULICZS-DISEASE
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7. Full Text Clonal expansion of CD4+ cytotoxic T lymphocytes in patients with IgG4 -related disease
by Mattoo, Hamid, PhD and Mahajan, Vinay S., MBBS, PhD and Maehara, Takashi, DDS, PhD and Deshpande, Vikram, MD and Della-Torre, Emanuel, MD and Wallace, Zachary S., MD and Kulikova, Maria, BS and Drijvers, Jefte M., MD and Daccache, Joe, BS and Carruthers, Mollie N., MD and Castelino, Flavia V., MD and Stone, James R., MD, PhD and Stone, John H., MD, MPH and Pillai, Shiv, MBBS, PhD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 138, Issue 3, pp. 825 - 838
Background IgG4 -related disease (IgG4 -RD) is a systemic condition of unknown cause characterized by highly fibrotic lesions with dense lymphoplasmacytic... 
Allergy and Immunology | TH2 cells | IgG4-related disease | Fibrosis | IgG4 | CD4+ cytotoxic T cells | IL-1β | rituximab | related disease | CD4 | 2 cells | IgG | cytotoxic T cells | T-Lymphocytes, Cytotoxic - immunology | Immunoglobulin G - blood | Humans | Middle Aged | Immune System Diseases - immunology | Immune System Diseases - blood | Male | Kidney - cytology | Lung - cytology | Lymph Nodes - cytology | Nasal Septum - cytology | Immunoglobulin G - immunology | Retroperitoneal Space | Submandibular Gland - cytology | Lymphocyte Count | Adult | Female | Aged | Cytokines - immunology | Wound healing | Disease | Cytokines | Pathogenesis | Cytotoxicity | Inflammatory diseases | Studies | Hospitals | Pulmonary fibrosis | Lymphocytes | Rodents | Fibroblasts | Extracellular matrix | Expansion | Age | Index Medicus | Abridged Index Medicus
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8. Full Text Graphene mechanical oscillators with tunable frequency
by Chen, Changyao and Lee, Sunwoo and Deshpande, Vikram V and Lee, Gwan-Hyoung and Lekas, Michael and Shepard, Kenneth and Hone, James
Nature Nanotechnology, ISSN 1748-3387, 2013, Volume 8, Issue 12, pp. 923 - 927
Oscillators, which produce continuous periodic signals from direct current power, are central to modern communications systems, with versatile applications... 
MONOLAYER GRAPHENE | FILMS | RESONATORS | MATERIALS SCIENCE, MULTIDISCIPLINARY | FEEDBACK OSCILLATOR | NANOSCIENCE & NANOTECHNOLOGY | STRENGTH | NOISE | Nanotechnology - instrumentation | Transducers | Mechanical Phenomena | Micro-Electrical-Mechanical Systems - instrumentation | Graphite - chemistry | Index Medicus | Graphene | Audio signals | Modulation | Nanostructure | Mechanical oscillators | Resonators | Frequency stability | Oscillators | Physics - Mesoscale and Nanoscale Physics
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9. Full Text Prediction of Cell Alignment on Cyclically Strained Grooved Substrates
by Ristori, Tommaso and Vigliotti, Andrea and Baaijens, Frank P.T and Loerakker, Sandra and Deshpande, Vikram S
Biophysical Journal, ISSN 0006-3495, 11/2016, Volume 111, Issue 10, pp. 2274 - 2285
Cells respond to both mechanical and topographical stimuli by reorienting and reorganizing their cytoskeleton. Under certain conditions, such as for cells on... 
RESPONSES | IN-VITRO | BIOPHYSICS | STRETCH | ORIENTATION | MECHANICAL MODEL | SMOOTH-MUSCLE-CELLS | EXTRACELLULAR-MATRIX | STRESS | CONTACT GUIDANCE | FIBROBLASTS | Biomechanical Phenomena | Signal Transduction | Models, Biological | Cytoskeleton - metabolism | Focal Adhesions | Stress, Mechanical | Diffusion | Analysis | Biomedical engineering | Cytoskeleton | Biophysics | Simulation | Cells | Substrates | Index Medicus | Cell Biophysics
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10. Full Text Microfabricated Tissue Gauges to Measure and Manipulate Forces from 3D Microtissues
by Wesley R. Legant and Amit Pathak and Michael T. Yang and Vikram S. Deshpande and Robert M. McMeeking and Christopher S. Chen and Robert Langer
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2009, Volume 106, Issue 25, pp. 10097 - 10102
Physical forces generated by cells drive morphologic changes during development and can feedback to regulate cellular phenotypes. Because these phenomena... 
Cantilevers | Morphogenesis | Fracture mechanics | Mechanical stress | Collagens | Stem cells | Cell lines | Actins | Stiffness | Endothelial cells | Biomechanics | Collagen | Cell mechanics | PDMS | COLLAGEN MATRICES | CELL CONTRACTILITY | cell mechanics | MULTIDISCIPLINARY SCIENCES | collagen | MUSCLE | biomechanics | CULTURE | FIBROBLASTS | ISOMETRIC CONTRACTION | IN-VITRO | morphogenesis | ENDOTHELIAL-CELLS | EXTRACELLULAR-MATRIX | NIH 3T3 Cells | Extracellular Matrix Proteins - chemistry | Animals | Microarray Analysis | Tissue Culture Techniques | Cytoskeleton | Mice | Miniaturization | Tissue Embedding - methods | Tissue Engineering | Microelectromechanical systems | Usage | Physiological aspects | Genetic aspects | Research | Methods | Proteins | Studies | Tissue | Genotype & phenotype | Correlation analysis | Three dimensional imaging | Cells | Index Medicus | Physical Sciences
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11. Introduction
by Deshpande, Vikram
Seminars in Diagnostic Pathology, ISSN 0740-2570, 11/2012, Volume 29, Issue 4, pp. 175 - 176
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12. Full Text Impact of granular slugs on rigid targets: Effect of grain shape and fracture
by Goel, A and Wadley, HNG and Deshpande, Vikram Sudhir
ISSN 0997-7538, 2018
The effect of grain shape and fracture on the interaction of high velocity granular slugs with rigid stationary targets is analysed for targets in normal and... 
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13. Full Text Inflammatory bowel disease-related dysplasia: evolving diagnostic and therapeutic paradigms
by Deshpande, Vikram
Diagnostic Histopathology, ISSN 1756-2317, 2015, Volume 21, Issue 8, pp. 340 - 347
Abstract Patients with inflammatory bowel disease show an excess colon cancer incidence and mortality. Colonoscopy with biopsies represents the most robust... 
Pathology | dysplasia | inflammatory bowel disease | p53 | Inflammatory bowel disease | Dysplasia | P53 | Immunohistochemistry | Gastrointestinal diseases | Colorectal cancer | Diagnosis | Tumor proteins | Health aspects
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14. Full Text Thermodynamic Modeling of the Statistics of Cell Spreading on Ligand-Coated Elastic Substrates
by McEvoy, Eoin and Shishvan, Siamak S and Deshpande, Vikram Sudhir and McGarry, J Patrick
ISSN 0006-3495, 2018
Biological spread cells exist in a perpetually fluctuating state, and therefore cannot be described in terms of a unique deterministic system. In order for... 
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15. Full Text A Bio-Chemo-Mechanical Model for Cell Contractility
by Vikram S. Deshpande and Robert M. McMeeking and Anthony G. Evans
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2006, Volume 103, Issue 38, pp. 14015 - 14020
A general model for the contractility of cells is presented that accounts for the dynamic reorganization of the cytoskeleton. The model is motivated by three... 
Gels | Anisotropy | Biochemical processes | Stress fibers | Actins | Fibroblasts | Cytoskeleton | Stiffness | Focal adhesions | Youngs modulus | Mechano-sensitivity | Self-assembly | Cell adhesion | self-assembly | cytoskeleton | COLLAGEN GELS | cell adhesion | MULTIDISCIPLINARY SCIENCES | STRESS | mechano-sensitivity | stress fibers | Cytoskeleton - metabolism | Mathematics | Models, Biological | Cell Physiological Phenomena | Actin | Myosin | Research | Chemical properties | Structure | Polymerization | Biochemistry | Cell adhesion & migration | Index Medicus | Biological Sciences
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16. Full Text IgG4‐Related Disease: Clinical and Laboratory Features in One Hundred Twenty‐Five Patients
by Wallace, Zachary S and Deshpande, Vikram and Mattoo, Hamid and Mahajan, Vinay S and Kulikova, Maria and Pillai, Shiv and Stone, John H
Arthritis & Rheumatology, ISSN 2326-5191, 09/2015, Volume 67, Issue 9, pp. 2466 - 2475
Objective. IgG4-related disease (IgG4-RD) is an immune-mediated fibroinflammatory condition that can affect nearly any organ. Prior studies have focused on... 
STATEMENT | DIAGNOSIS | MULTICENTER | AUTOIMMUNE PANCREATITIS | RITUXIMAB | SERUM IGG4 CONCENTRATIONS | EXTRAPANCREATIC LESIONS | COHORT | RHEUMATOLOGY | Autoimmune Diseases - physiopathology | Glucocorticoids - therapeutic use | Age Factors | Humans | Middle Aged | Autoimmune Diseases - immunology | Male | Treatment Outcome | Eosinophils - immunology | Young Adult | Flow Cytometry | Immunoglobulin G - immunology | Aged, 80 and over | Adult | Female | Aged | Leukocyte Count | Retrospective Studies | Eosinophils - cytology | Autoimmune Diseases - drug therapy | Plasma Cells - cytology | Cohort Studies | Plasma Cells - immunology | Biopsy | Laboratories | Index Medicus | Abridged Index Medicus
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17. Full Text Water rise in a cellulose foam: By capillary or diffusional flow?
by Mirzajanzadeh, Morad and Deshpande, Vikram Sudhir and Fleck, Norman Andrew
ISSN 0022-5096, 2019
Critical experiments and predictive models reveal that water rise through a cellulose foam is initially by capillary rise, followed by non-linear diffusion in... 
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18. Full Text The tensile ductility of cellular Solids: The role of imperfections
by Ronan, William and Deshpande, Vikram S and Fleck, Norman A
International Journal of Solids and Structures, ISSN 0020-7683, 12/2016, Volume 102-103, pp. 200 - 213
Metallic and polymeric foams typically possess a low tensile failure strain of a few percent despite the fact that the parent solid can have high ductility... 
Micro-mechanics | Elastic plastic solids | Cellular foams | Foam structures | Tension | Stress strain | Finite element | Biological products | Axial stress | Stress state | Honeycomb construction | Ductility | Inclusions | Strain | Finite element method | Foamed metals | Misalignment | Finite element analysis | Microstructure | Beams (structural) | Plastic foam
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19. IgG4-related disease. Introduction
by Deshpande, Vikram
Seminars in diagnostic pathology, ISSN 0740-2570, 11/2012, Volume 29, Issue 4, p. 175
Biomarkers - metabolism | Immunoglobulin G - blood | Humans | Immunosuppressive Agents - therapeutic use | Male | Autoimmune Diseases - diagnosis | Pancreatitis, Chronic - pathology | Mikulicz' Disease - metabolism | Pancreatitis, Chronic - metabolism | Autoimmune Diseases - metabolism | Autoimmune Diseases - drug therapy | Mikulicz' Disease - pathology | Practice Guidelines as Topic
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