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The EMBO Journal, ISSN 0261-4189, 11/2001, Volume 20, Issue 21, pp. 5863 - 5875
Journal Article
Nature Communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 1268 - 13
Journal Article
The EMBO Journal, ISSN 0261-4189, 11/2001, Volume 20, Issue 21, pp. 5876 - 5886
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 10/2019, Volume 9, Issue 1, pp. 15699 - 9
... Aguilar-calvo1, Marie-christine Birling3, José Luis pitarch1, Jean-philippe Deslys2 and Juan María torres 1* cynomolgus macaque has been used for the evaluation... 
SCRAPIE | PRPSC ACCUMULATION | BOVINE SPONGIFORM ENCEPHALOPATHY | MULTIDISCIPLINARY SCIENCES | CYNOMOLGUS MACAQUES | BETA-2-ALPHA-2 LOOP | HUMAN TRANSMISSION | MICE | CHRONIC WASTING DISEASE | BSE TRANSMISSION | VARIANT | Animal models | BSE | Rodents | Encephalopathy | Transgenic mice | Amino acid sequence | Amino acids | Prion protein | Bovine spongiform encephalopathy | Zoonoses
Journal Article
Journal Article
PLOS ONE, ISSN 1932-6203, 12/2018, Volume 13, Issue 12, p. e0209150
Human mini-brains (MB) are cerebral organoids that recapitulate in part the complexity of the human brain in a unique three-dimensional in vitro model,... 
CELLS | IN-VITRO | PRION PROTEIN PRPC | GENE | MULTIDISCIPLINARY SCIENCES | A-BETA | LESSONS | EXPRESSION | Small Molecule Libraries - pharmacology | Peptide Fragments - metabolism | Amyloid beta-Peptides - biosynthesis | Humans | Protein Multimerization | Protein Structure, Quaternary - drug effects | Peptide Fragments - biosynthesis | Alzheimer Disease - pathology | Gene Expression Regulation - drug effects | Peptide Fragments - chemistry | Phenotype | Organoids - metabolism | Amyloid beta-Peptides - metabolism | Organoids - drug effects | Brain - pathology | Amyloid beta-Peptides - chemistry | PrPC Proteins - metabolism | Brain | Cell culture | Animal models | Cerebral cortex | Peptides | Laboratories | Disorders | Infections | Accumulation | Proteins | Oligomers | Time dependence | Organoids | Transgenic animals | Post-translation | Amyloid | Physiology | Conditioning | Prion protein | Alzheimer's disease | Neurological disorders | Age | Phenotypes | Neurodegenerative diseases | Secretion | Metabolism | Gene expression | Chemical compounds | Patients | Amyloid precursor protein | Neurological diseases | Organic chemistry | Pathology | Brain research | Prions | Stem cells | Neural stem cells | Mutation | Alzheimers disease | Three dimensional models | Pluripotency | Life Sciences | Biotechnology | Cellular Biology | Neurons and Cognition | Neurobiology
Journal Article
Journal Article
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 11/2019, Volume 9, Issue 1, pp. 16310 - 11
..., narciso costa1, frédéric théodoro4, ferid nassor 2,3, Alain pruvost 4, nicolas tournier5, Yulia Kiyan 6, oliver Langer7,8, Frank Yates 2,3, Jean philippe Deslys2... 
TRANSPORT | POSITRON-EMISSION-TOMOGRAPHY | INHIBITION | ABCB1 | MULTIDISCIPLINARY SCIENCES | ENDOTHELIAL-CELLS | PET | STRATEGIES | DELIVERY | ABCG2 | Brain | Central nervous system | Membrane permeability | Radioisotopes | Permeability | Drug screening | Drug development | Blood-brain barrier | Stem cells | Positron emission tomography | Pluripotency | Physicochemical properties | Inhibitory postsynaptic potentials
Journal Article
Prion, ISSN 1933-6896, 07/2018, Volume 12, Issue 3-4, pp. 162 - 169
The recently reevaluated high prevalence of healthy carriers (1/2,000 in UK) of variant Creutzfeldt-Jakob Disease (v-CJD), whose blood might be infectious,... 
spinal cord disease | vCJD | macaque | mouse | demyelination | transfusion | (5-10): prion | abnormal PrP | spongiform change | myelopathy | NONHUMAN-PRIMATES | ORAL INFECTION | PROTEIN | FLAIL ARM SYNDROME | BIOCHEMISTRY & MOLECULAR BIOLOGY | VARIANT | AGENT | BOVINE SPONGIFORM ENCEPHALOPATHY | CREUTZFELDT-JAKOB-DISEASE | SCRAPIE-INFECTED BRAIN | BLOOD
Journal Article