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Clinical Cancer Research, ISSN 1078-0432, 01/2017, Volume 23, Issue 2, pp. 523 - 535
Purpose: PARP inhibitors (PARPi) are a novel class of small molecule therapeutics for small cell lung cancer (SCLC). Identification of predictors of response... 
BREAST-CANCER | TRIAL | INACTIVATION | ONCOLOGY | ABT-888 | PHASE-II | BRCA1 | DNA-REPAIR | DRUG RESPONSE | POLY(ADP-RIBOSE) POLYMERASE INHIBITOR | BMN 673 | Piperazines - administration & dosage | Dacarbazine - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Phthalazines - administration & dosage | Humans | Etoposide - administration & dosage | Small Cell Lung Carcinoma - genetics | Small Cell Lung Carcinoma - drug therapy | Indoles - administration & dosage | Poly (ADP-Ribose) Polymerase-1 - antagonists & inhibitors | Cisplatin - administration & dosage | Poly(ADP-ribose) Polymerase Inhibitors - administration & dosage | Drug Synergism | Xenograft Model Antitumor Assays | Small Cell Lung Carcinoma - pathology | Animals | Benzimidazoles - administration & dosage | Dacarbazine - analogs & derivatives | Cell Line, Tumor | Mice | Gene Expression Regulation, Neoplastic - drug effects | Genomics - methods | Nuclear Proteins - genetics | Poly (ADP-Ribose) Polymerase-1 - genetics | Immunohistochemistry | CRISPR | Therapy | Effectiveness | Transcription | Small cell lung carcinoma | Lung cancer | Etoposide | Poly(ADP-ribose) polymerase | Immunoblotting | Single-nucleotide polymorphism | Gene expression | Cisplatin | Scars | Inhibitors | Experimental design | Correlation analysis | Xenografts | Biomarkers | In vivo methods and tests | Temozolomide | Viability | Combinatorial analysis | Cancer | SLFN11 | small cell lung cancer | biomarker | PARP inhibition | patient-derived xenografts
Journal Article
Atlanta Review, ISSN 1073-9696, 09/2018, Volume 25, Issue 1, p. 21
Journal Article
Human Pathology, ISSN 0046-8177, 2015, Volume 46, Issue 5, pp. 739 - 745
Journal Article
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, ISSN 0893-3952, 02/2020, Volume 33, Issue 2, pp. 303 - 311
V-domain Ig-containing suppressor of T-cell activation (VISTA) is an immune checkpoint gene that inhibits anti-tumor immune responses. Since most malignant... 
Immunohistochemistry | Immunoglobulins | Mesothelium | Statistical analysis | Immune response | Benign | Cytotoxicity | Mesothelioma | Genomes | Lymphocytes T | Inflammation | CTLA-4 protein | Cell activation | Immune checkpoint | DNA microarrays | Cell death | Immunotherapy | PD-L1 protein | Pleura | Apoptosis | Tumors
Journal Article
Journal Article
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2017, Volume 35, Issue 15_suppl, pp. 11600 - 11600
Journal Article
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 2011, Volume 253, Issue 2, pp. 94 - 102
Healthy oocytes are critical for producing healthy children, but little is known about whether or not oocytes have the capacity to identify and recover from... 
H2AX | Ovary | Cyclophosphamide | DNA damage | Follicle | Ovarian toxicity | Oocyte | SYSTEMIC-LUPUS-ERYTHEMATOSUS | RAT | DOUBLE-STRAND BREAKS | CYCLOPHOSPHAMIDE TREATMENT | HISTONE H2AX | TOXICITY | CHILDHOOD-CANCER SURVIVOR | FERTILITY | FOLLICULAR DEVELOPMENT | PHARMACOLOGY & PHARMACY | TOXICOLOGY | YOUNG-WOMEN | Phosphoramide Mustards - toxicity | Species Specificity | Rats | DNA Breaks, Double-Stranded | Rats, Sprague-Dawley | Ovarian Follicle - drug effects | Animals | Histones - analysis | Oocytes - drug effects | Female | Mice | In Vitro Techniques | Ovarian Follicle - cytology | Immunohistochemistry | Analysis | DNA | Radiation | Dimethyl sulfoxide | Phosphotransferases | Index Medicus | Ovarian Follicle | Oocytes | Life Sciences | Toxicology | Histones | Phosphoramide Mustards | ANTIBODIES | SENSITIVITY | 60 APPLIED LIFE SCIENCES | DNA DAMAGES | IN VITRO | CHEMICAL REACTIONS | RADIATIONS | VERTEBRATES | DETECTION | ENDOXAN | INJURIES | ADULTS | TRANSFERASES | DAMAGE | IONIZING RADIATIONS | PLANTS | IMMUNOSUPPRESSIVE DRUGS | MAN | BODY | CONTROL | HAZARDS | PHOSPHORYLATION | BRASSICA | RATS | NUCLEIC ACIDS | PRIMATES | STRAND BREAKS | GONADS | PHOSPHORUS-GROUP TRANSFERASES | ENZYMES | DRUGS | OVARIES | MAGNOLIOPHYTA | OOCYTES | MICE | VEGETABLES | AGE GROUPS | MAMMALS | ANIMALS | RODENTS | ORGANIC COMPOUNDS | MAGNOLIOPSIDA | ALKYLATING AGENTS | IN VIVO | PROGENY | CHILDREN | FEMALE GENITALS | ORGANS | DISEASES | GERM CELLS | PHOSPHOTRANSFERASES | PROTEINS | FOOD
Journal Article
JOURNAL OF THORACIC ONCOLOGY, ISSN 1556-0864, 12/2019, Volume 14, Issue 12, pp. 2062 - 2070
Introduction: Molecules targeting programmed cell death 1 or its ligand programmed death ligand 1 (PD-L1) revolutionized the treatment of patients with NSCLC.... 
PD-L1 immunohistochemistry | Quality assurance | PEMBROLIZUMAB | ONCOLOGY | CYTOLOGY SPECIMENS | PHASE-1 | RESPIRATORY SYSTEM | Non-small cell lung cancer | Cytology | CARCINOMA | LIGAND 1 EXPRESSION | IMMUNOHISTOCHEMISTRY
Journal Article
CLINICAL CANCER RESEARCH, ISSN 1078-0432, 08/2019, Volume 25, Issue 15, pp. 4712 - 4722
Purpose: Targeted next-generation sequencing of DNA has become more widely used in the management of patients with lung adenocarcinoma; however, no clear... 
GENE FUSIONS | IMPACT | PAN-TRK | GENOMICS | SOLID TUMORS | ONCOLOGY | IMMUNOTHERAPY | CLINICAL CHARACTERISTICS | IDENTIFICATION | CANCER | ROS1
Journal Article