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Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 5425 - 5425
Abstract The use of tyrosine kinase inhibitors (TKI) has dramatically changed the natural history and the prognosis of CML with a major improvement of survival... 
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 5495 - 5495
Abstract Myelodysplastic syndromes (MDS) are clonal malignancies of the hematopoietic stem cell leading to an ineffective hematopoiesis with a complex and... 
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 934 - 934
Abstract Recent experimental data suggest that the heterogeneity of CML stem cells can be due not only to their differential BCR-ABL expression but also to the... 
Journal Article
Nature Communications, ISSN 2041-1723, 07/2016, Volume 7, Issue 1, p. 12203
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2018, Volume 13, Issue 8, p. e0200923
Aryl Hydrocarbon Receptor (AHR) is an ubiquitous basic helix-loop-helix transcription factor, which is ligand-activated and involved in numerous biological... 
Neoplastic Stem Cells - drug effects | Humans | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics | RNA, Messenger - metabolism | RNA, Neoplasm - metabolism | Case-Control Studies | Basic Helix-Loop-Helix Transcription Factors - metabolism | Neoplastic Stem Cells - metabolism | Neoplastic Stem Cells - pathology | Receptors, Aryl Hydrocarbon - metabolism | Gene Expression Regulation, Neoplastic - drug effects | Tumor Stem Cell Assay | Basic Helix-Loop-Helix Transcription Factors - agonists | Basic Helix-Loop-Helix Transcription Factors - genetics | Purines - pharmacology | RNA, Messenger - genetics | Receptors, Aryl Hydrocarbon - genetics | Receptors, Aryl Hydrocarbon - agonists | Fusion Proteins, bcr-abl - genetics | Signal Transduction - drug effects | Cell Line, Tumor | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - metabolism | RNA, Neoplasm - genetics | Cell Proliferation - drug effects | Carbazoles - pharmacology | Fusion Proteins, bcr-abl - metabolism | Cell proliferation | BCR protein | Cell culture | Circuits | Leukemia | Genes | Medical services | Hydrocarbons | Stem cell transplantation | Colony-forming cells | Kinases | Multivariate analysis | DNA repair | Hematopoietic stem cells | Aromatic compounds | CD38 antigen | Down-regulation | Cell cycle | Peripheral blood | Helix-loop-helix proteins | Fusion protein | CD34 antigen | Phenotypes | Imatinib | Cytokines | Myeloid leukemia | Cell division | Abl protein | Chronic myeloid leukemia | Gene expression | Biological activity | Hemopoiesis | Medicine | Stem cells | Synergistic effect
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2015, Volume 10, Issue 6, p. e0130559
Journal Article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, ISSN 1422-0067, 04/2019, Volume 20, Issue 7, p. 1737
Although human pluripotent stem cells (hPSCs) can theoretically differentiate into any cell type, their ability to produce hematopoietic cells is highly... 
microRNAs | embryonic stem cells | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | miR-206 | SIGNATURE | CHEMISTRY, MULTIDISCIPLINARY | ROLES | LIVER | MIR-142-3P | HEMANGIOBLASTS | induced pluripotent stem cells | hematopoietic potential | GENERATION | DIFFERENTIATION | Human pluripotent stem cells | REVEALS
Journal Article
British Journal of Cancer, ISSN 0007-0920, 09/2017, Volume 117, Issue 7, pp. 965 - 973
Background: The hepatic artery infusion (HAI) of irinotecan, oxaliplatin and 5-fluorouracil with intravenous cetuximab achieved outstanding efficacy in... 
conversion-to-resection | hepatic artery infusion | early response | liver metastases | pharmacogenetics | CELLS | RESECTION | LONG-TERM SURVIVAL | OXALIPLATIN | PROLIFERATION | POLYMORPHISM | CHEMOTHERAPY | CAPECITABINE | 5-FLUOROURACIL | ONCOLOGY | VITAMIN-K | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Colorectal Neoplasms - genetics | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Catecholamine Plasma Membrane Transport Proteins - genetics | Diarrhea - chemically induced | Hepatectomy | Glucuronosyltransferase - genetics | Organoplatinum Compounds - administration & dosage | Fluorouracil - administration & dosage | Adult | Camptothecin - administration & dosage | Female | Liver Neoplasms - secondary | Neutropenia - chemically induced | Neutropenia - genetics | Camptothecin - analogs & derivatives | Vitamin K Epoxide Reductases - genetics | Pharmacogenetics | Liver Neoplasms - genetics | Hepatic Artery | Liver Neoplasms - drug therapy | Cytochrome P-450 CYP2C19 - genetics | Liver Neoplasms - surgery | Survival Rate | Treatment Outcome | Cytochrome P-450 CYP2C9 - genetics | Disease-Free Survival | Administration, Intravenous | Diarrhea - genetics | Cetuximab - administration & dosage | Aged | Arylamine N-Acetyltransferase - genetics | Polymorphism, Single Nucleotide | Colorectal Neoplasms - pathology | ATP Binding Cassette Transporter, Sub-Family B - genetics | Infusions, Intra-Arterial | Intravenous administration | 5-Fluorouracil | Toxicity | Identification methods | Liver | Colorectal carcinoma | Colorectal cancer | Leukocytes (mononuclear) | Single-nucleotide polymorphism | Metastasis | Metastases | Liver cancer | Infusion | Oxaliplatin | Surgery | N-Acetyltransferase 2 | Acetyltransferase | Neutropenia | Hepatic artery | N-Acetyltransferase | Diarrhea | Pharmacology | Patients | Survival | Irinotecan | Cancer | Polymorphism | Translational Therapeutics
Journal Article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, ISSN 1422-0067, 10/2019, Volume 20, Issue 19, p. 4867
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 08/2018, Volume 366, Issue 2, pp. 238 - 243
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 1275 - 1275
Abstract Although human pluripotent stem cells (hPSCs) can theoretically be differentiated into any cell type, their ability to generate hematopoietic cells... 
Journal Article
Blood, ISSN 0006-4971, 12/2015, Volume 126, Issue 23, pp. 2823 - 2823
Abstract BACKGROUND The dynamic relationship between HSC, their niches and the trabecular bone is disrupted in MPN as primary myelofibrosis (PMF). PMF is... 
Journal Article
Blood, ISSN 0006-4971, 12/2014, Volume 124, Issue 21, pp. 1873 - 1873
Abstract Primary myelofibrosis (PMF) is myeloproliferative neoplasm characterized by clonal myeloproliferation, dysmegakaryopoiesis, extramedullary... 
Journal Article
Oncotarget, ISSN 1949-2553, 04/2019, Volume 10, Issue 28, p. 2693
Recent development of cell reprogramming technologies brought a major hope for future cell therapy applications by the use of these cells or their derivatives.... 
Journal Article
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 4139 - 4139
Acute myeloid leukemias (AMLs) are heterogenous diseases often resulting from the acquisition of multiple genetic alterations that deregulate hematopoietic... 
Journal Article
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