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by Marouli, Eirini and Graff, Mariaelisa and Medina-Gomez, Carolina and Lo, Ken Sin and Wood, Anew R and Kjaer, Troels R and Fine, Rebecca S and Lu, Yingchang and Schurmann, Claudia and Highland, Heather M and Rüeger, Sina and Thorleifsson, Gudmar and Justice, Anne E and Lamparter, David and Stirrups, Kathleen E and Turcot, Valérie and Young, Kristin L and Winkler, Thomas W and Esko, Tõnu and Karaderi, Tugce and Locke, Adam E and Masca, Nicholas G. D and Ng, Maggie C. Y and Mudgal, Poorva and Rivas, Manuel A and Vedantam, Sailaja and Mahajan, Anubha and Guo, Xiuqing and Abecasis, Goncalo and Aben, Katja K and Adair, Linda S and Alam, Dewan S and Albrecht, Eva and Allin, Kristine H and Allison, Matthew and Amouyel, Philippe and Appel, Emil V and Arveiler, Dominique and Asselbergs, Folkert W and Auer, Paul L and Balkau, Beverley and Banas, Bernhard and Bang, Lia E and Benn, Marianne and Bergmann, Sven and Bielak, Lawrence F and Blüher, Matthias and Boeing, Heiner and Boerwinkle, Eric and Böger, Carsten A and Bonnycastle, Lori L and Bork-Jensen, Jette and Bots, Michiel L and Bottinger, Erwin P and Bowden, Donald W and Brandslund, Ivan and Breen, Gerome and Brilliant, Murray H and Broer, Linda and Burt, Amber A and Butterworth, Adam S and Carey, David J and Caulfield, Mark J and Chambers, John C and Chasman, Daniel I and Chen, Yii-Der Ida and Chowdhury, Rajiv and Christensen, Cramer and Chu, Auey Y and Cocca, Massimiliano and Collins, Francis S and Cook, James P and Corley, Janie and Galbany, Jordi Corominas and Cox, Amanda J and Cuellar-Partida, Gabriel and Danesh, John and Davies, Gail and de Bakker, Paul I. W and de Borst, Gert J and de Denus, Simon and de Groot, Mark C. H and de Mutsert, Renée and Deary, Ian J and Dedoussis, George and Demerath, Ellen W and den Hollander, Anneke I and Dennis, Joe G and Di Angelantonio, Emanuele and nos, Fotios and Du, Mengmeng and Dunning, Alison M and Easton, Douglas F and Ebeling, Tapani and Edwards, Todd L and Ellinor, Patrick T and Elliott, Paul and Evangelou, Evangelos and Farmaki, Aliki-Eleni and Faul, Jessica D and ... and EPIC-CVD Consortium and GoT2D Genes Consortium and MAGIC Investigators and Global Lipids Genetics Consortium and EPIC-InterAct Consortium and ReproGen Consortium and ExomeBP Consortium and CHD Exome Consortium and T2D-Genes Consortium and The EPIC-InterAct Consortium and CHD Exome+ Consortium and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Enheten för biobanksforskning and Allmänmedicin and Umeå universitet and Medicin
Nature, ISSN 0028-0836, 2017, Volume 542, Issue 7640, pp. 186 - 190
Journal Article
by Liu, Dajiang J and Peloso, Gina M and Yu, Haojie and Butterworth, Adam S and Wang, Xiao and Mahajan, Anubha and Saleheen, Danish and Emdin, Connor and Alam, Dewan and Alves, Alexessander Couto and Amouyel, Philippe and Di Angelantonio, Emanuele and Arveiler, Dominique and Assimes, Themistocles L and Auer, Paul L and Baber, Usman and Ballantyne, Christie M and Bang, Lia E and Benn, Marianne and Bis, Joshua C and Boehnke, Michael and Boerwinkle, Eric and Bork-Jensen, Jette and Bottinger, Erwin P and Brandslund, Ivan and Brown, Morris and Busonero, Fabio and Caulfield, Mark J and Chambers, John C and Chasman, Daniel I and Chen, Y. Eugene and Chen, Yii-Der Ida and Chowdhury, Rajiv and Christensen, Cramer and Chu, Auey Y and Connell, John M and Cucca, Francesco and Cupples, L. Aienne and Damrauer, Scott M and Davies, Gail and Deary, Ian J and Dedoussis, George and Denny, Joshua C and Dominiczak, Anna and Dubé, Marie-Pierre and Ebeling, Tapani and Eiriksdottir, Gudny and Esko, Tõnu and Farmaki, Aliki-Eleni and Feitosa, Mary F and Ferrario, Marco and Ferrieres, Jean and Ford, Ian and Fornage, Myriam and Franks, Paul W and Frayling, Timothy M and Frikke-Schmidt, Ruth and Fritsche, Lars G and Frossard, Philippe and Fuster, Valentin and Ganesh, Santhi K and Gao, Wei and Garcia, Melissa E and Gieger, Christian and Giulianini, Franco and Goodarzi, Mark O and Grallert, Harald and Grarup, Niels and Groop, Leif and Grove, Megan L and Gudnason, Vilmundur and Hansen, Torben and Harris, Tamara B and Hayward, Caroline and Hirschhorn, Joel N and Holmen, Oddgeir L and Huffman, Jennifer and Huo, Yong and Hveem, Kristian and Jabeen, Sehrish and Jackson, Anne U and Jakobsdottir, Johanna and Jarvelin, Marjo-Riitta and Jensen, Gorm B and Jørgensen, Marit E and Jukema, J. Wouter and Justesen, Johanne M and Kamstrup, Pia R and Kanoni, Stavroula and Karpe, Freik and Kee, Frank and Khera, Amit V and Klarin, Derek and Koistinen, Heikki A and Kooner, Jaspal S and Kooperberg, Charles and Kuulasmaa, Kari and Kuusisto, Johanna and Laakso, Markku and Lakka, Timo and ... and VA Million Veteran Program and Charge Diabet Working Grp and EPIC-CVD Consortium and EPIC-InterAct Consortium and GOLD Consortium and Charge Diabetes Working Group and The EPIC-InterAct Consortium and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Enheten för biobanksforskning and Umeå universitet and Medicin
Nature genetics, ISSN 1061-4036, 2017, Volume 49, Issue 12, pp. 1758 - 1766
We screened variants on an exome-focused genotyping array in >300,000 participants (replication in >280,000 participants) and identified 444 independent... 
APOBEC-1 COMPLEMENTATION FACTOR | MYELOPROLIFERATIVE DISORDERS | LOW-FREQUENCY | CLONAL HEMATOPOIESIS | B MESSENGER-RNA | GENETICS & HEREDITY | TYROSINE KINASE JAK2 | CARDIOVASCULAR-DISEASE | MACULAR DEGENERATION | GENETIC ARCHITECTURE | CODING-SEQUENCE VARIANTS | Genetic Predisposition to Disease - genetics | Diabetes Mellitus, Type 2 - genetics | Humans | Risk Factors | Genetic Association Studies - methods | Genotype | Coronary Artery Disease - blood | Macular Degeneration - blood | Genetic Variation | Diabetes Mellitus, Type 2 - blood | Exome - genetics | Phenotype | Macular Degeneration - genetics | Lipids - blood | Coronary Artery Disease - genetics | Genome-wide association studies | Genetic aspects | Blood lipids | Identification and classification | Methods | Plasma | Lipoproteins (low density) | Liver | Lipids | Risk | Cardiovascular disease | Genomes | Macular degeneration | Consortia | Janus kinase 2 | Heart diseases | Lipoproteins (high density) | Age | Diabetes mellitus | Coronary artery | Health risks | Thalassemia | Triglycerides | Coronary artery disease | Loci | Cholesterol | Lipolysis | Studies | Lipoproteins | Genotyping | Alleles | Quality control | Diabetes | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
by Surenan, P and nos, Fotios and Young, Robin and Warren, Helen and Cook, J.P and Manning, Alisa and Grarup, Niels and Sim, Xueling and Barnes, Daniel and Witkowska, Ewa and Staley, James R and Tragante, Vinicius and Tukiainen, Taru and Yaghootkar, Hanieh and Masca, N and Freitag, Christine and Ferreira, Teresa and Giannakopoulou, Olga and Tinker, A and Harakalova, Magdalena and Mihailov, Evelin and Liu, C and Kraja, Aldi and Nielsen, Sune and Rasheed, Asif and Samuel, Maria and Zhao, Wei and Bonnycastle, Lori and Jackson, Anne and Narisu, Narisu and Swift, Amy and Southam, Lorraine and Marten, Jonathan and Huyghe, Jeroen R and Stancáková, Alena and Fava, Cristiano and Ohlsson, T and Matchan, Angela and Stirrups, Kathy and Bork-Jensen, Jette and Gjesing, Anette and Kontto, J and Perola, Markus and Shaw-Hawkins, Sue and Havulinna, Aki and Zhang, H and Donnelly, Louise and Groves, Christopher and Rayner, Nigel William and Neville, Matthew and Robertson, Neil and Yiorkas, A.M and Herzig, K.H and Kajantie, Eero and Zhang, Weihua and Willems, Sara and Lannfelt, Lars and Malerba, Giovanni and Soranzo, Nicole and Trabetti, Elisabetta and Verweij, Niek and Evangelou, Evangelos and Moayyeri, Alireza and Vergnaud, A.-C and Nelson, Christopher P and Poveda, A and Varga, Tibor V and Caslake, Muriel and De Craen, Anton J. M and Trompet, Stella and Luan, Jian'An and Scott, Robert and Harris, Sarah and Liewald, David C and Marioni, Riccardo and Menni, Cristina and Farmaki, Aliki-Eleni and Hallmans, Göran and Renström, Frida and Huffman, Jennifer and Hassinen, M and Burgess, Stephen and Vasan, R.S and Felix, Janine and Uria-Nickelsen, M and Mälarstig, Anders and Reilly, D.F and Hoek, M and Vogt, T.F and Lin, Honghuang and Lieb, Wolfgang and Traylor, Matthew and Markus, Hugh and Highland, Heather and Justice, Anne and Marouli, Eirini and Lindström, Jaana and Uusitupa, Matti and Komulainen, Pirjo and Lakka, Timo and ... and Understanding Soc Sci Grp and Wellcome Trust Case Control Consor and GoT2DGenes Consortium and ExomeBP Consortium and CHD Exome Consortium and Giant Consortiumm and CHARGE Exome Chip Blood Pressure C and EPIC-CVD Consortium and CHARGE Heart Failure Consortiumm and EchoGen Consortiumm and EPIC-InterAct Consortium and Lifelines Cohort Study and Metastroke Consortiumm and T2D-GENES Consortium and Wellcome Trust Case Control Consortium and Understanding Society Scientific Group and EchoGen Consortium and CHD Exome+ Consortium and CHARGE+ Exome Chip Blood Pressure Consortium and CHARGE-Heart Failure Consortium and METASTROKE Consortium and GIANT Consortium and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Enheten för biobanksforskning and Allmänmedicin and Umeå universitet and Medicin
Nature Genetics, ISSN 1061-4036, 10/2016, Volume 48, Issue 10, pp. 1151 - 1161
Journal Article
by Turcot, Valérie and Lu, Yingchang and Highland, Heather M and Schurmann, Claudia and Justice, Anne E and Fine, Rebecca S and Bradfield, Jonathan P and Esko, Tõnu and Giri, Ayush and Graff, Mariaelisa and Guo, Xiuqing and Hendricks, Audrey E and Karaderi, Tugce and Lempradl, Adelheid and Locke, Adam E and Mahajan, Anubha and Marouli, Eirini and Sivapalaratnam, Suthesh and Young, Kristin L and Alfred, Tamuno and Feitosa, Mary F and Masca, Nicholas G. D and Manning, Alisa K and Medina-Gomez, Carolina and Mudgal, Poorva and Ng, Maggie C. Y and Reiner, Alex P and Vedantam, Sailaja and Willems, Sara M and Winkler, Thomas W and Abecasis, Gonçalo and Aben, Katja K and Alam, Dewan S and Alharthi, Sameer E and Allison, Matthew and Amouyel, Philippe and Asselbergs, Folkert W and Auer, Paul L and Balkau, Beverley and Bang, Lia E and Barroso, Inês and Bastarache, Lisa and Benn, Marianne and Bergmann, Sven and Bielak, Lawrence F and Blüher, Matthias and Boehnke, Michael and Boeing, Heiner and Boerwinkle, Eric and Böger, Carsten A and Bork-Jensen, Jette and Bots, Michiel L and Bottinger, Erwin P and Bowden, Donald W and Brandslund, Ivan and Breen, Gerome and Brilliant, Murray H and Broer, Linda and Brumat, Marco and Burt, Amber A and Butterworth, Adam S and Campbell, Peter T and Cappellani, Stefania and Carey, David J and Catamo, Eulalia and Caulfield, Mark J and Chambers, John C and Chasman, Daniel I and Chen, Yii-Der I and Chowdhury, Rajiv and Christensen, Cramer and Chu, Audrey Y and Cocca, Massimiliano and Cook, James P and Corley, Janie and Corominas Galbany, Jordi and Cox, Amanda J and Crosslin, David S and Cuellar-Partida, Gabriel and D'Eustacchio, Angela and Danesh, John and Davies, Gail and Bakker, Paul I. W and Groot, Mark C. H and Mutsert, Renée and Deary, Ian J and Dedoussis, George and Demerath, Ellen W and Heijer, Martin and Hollander, Anneke I and Ruijter, Hester M and Dennis, Joe G and Denny, Josh C and Angelantonio, Emanuele and Drenos, Fotios and Du, Mengmeng and Dubé, Marie-Pierre and Dunning, Alison M and Easton, Douglas F and Edwards, Todd L and ... and Chd Exome Consortium and EPIC InterAct Consortium and Global Lipids Genetic Consortium and GoT2D Genes Consortium and MAGIC Investigators and Understanding Soc Sci Grp and ReproGen Consortium and Interval Study and Epic-Cvd Consortium and ExomeBP Consortium and T2D-Genes Consortium and INTERVAL Study and EPIC-CVD Consortium and EPIC InterAct Consortium and CHD Exome+ Consortium and Understanding Society Scientific Group and The MAGIC Investigators and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Enheten för biobanksforskning and Allmänmedicin and Umeå universitet and Medicin
Nature Genetics, ISSN 1061-4036, 01/2018, Volume 50, Issue 1, pp. 26 - 35
Journal Article
FEBS Open Bio, ISSN 2211-5463, 03/2018, Volume 8, Issue 3, pp. 426 - 434
DNA repair consists of several cellular pathways which recognize and repair damaged DNA. The classical nonhomologous DNA end‐joining (NHEJ) pathway repairs... 
mouse genetics | C9orf142 | Cernunnos | T‐FISH | XLS | lymphocyte | T-FISH | DNA-REPAIR FACTORS | INTERPLAY | STRAND BREAK REPAIR | BIOCHEMISTRY & MOLECULAR BIOLOGY | V(D)J RECOMBINATION | DEFICIENT MICE | FUNCTIONAL REDUNDANCY | OVERLAPPING FUNCTIONS | SYNTHETIC LETHALITY | EMBRYONIC LETHALITY
Journal Article
by Justice, Anne E and Karaderi, Tugce and Highland, Heather M and Young, Kristin L and Graff, Mariaelisa and Lu, Yingchang and Turcot, Valérie and Auer, Paul L and Fine, Rebecca S and Guo, Xiuqing and Schurmann, Claudia and Lempradl, Adelheid and Marouli, Eirini and Mahajan, Anubha and Winkler, Thomas W and Locke, Adam E and Medina-Gomez, Carolina and Esko, Tõnu and Vedantam, Sailaja and Giri, Ayush and Lo, Ken Sin and Alfred, Tamuno and Mudgal, Poorva and Ng, Maggie C. Y and Heard-Costa, Nancy L and Feitosa, Mary F and Manning, Alisa K and Willems, Sara M and Sivapalaratnam, Suthesh and Abecasis, Goncalo and Alam, Dewan S and Allison, Matthew and Amouyel, Philippe and Arzumanyan, Zorayr and Balkau, Beverley and Bastarache, Lisa and Bergmann, Sven and Bielak, Lawrence F and Blüher, Matthias and Boehnke, Michael and Boeing, Heiner and Boerwinkle, Eric and Böger, Carsten A and Bork-Jensen, Jette and Bottinger, Erwin P and Bowden, Donald W and Brandslund, Ivan and Broer, Linda and Burt, Amber A and Butterworth, Adam S and Caulfield, Mark J and Cesana, Giancarlo and Chambers, John C and Chasman, Daniel I and Chen, Yii-Der Ida and Chowdhury, Rajiv and Christensen, Cramer and Chu, Audrey Y and Collins, Francis S and Cook, James P and Cox, Amanda J and Crosslin, David S and Danesh, John and de Bakker, Paul I. W and Denus, Simon de and Mutsert, Renée de and Dedoussis, George and Demerath, Ellen W and Dennis, Joe G and Denny, Josh C and Angelantonio, Emanuele Di and Dörr, Marcus and Drenos, Fotios and Dubé, Marie-Pierre and Dunning, Alison M and Easton, Douglas F and Elliott, Paul and Evangelou, Evangelos and Farmaki, Aliki-Eleni and Feng, Shuang and Ferrannini, Ele and Ferrieres, Jean and Florez, Jose C and Fornage, Myriam and Fox, Caroline S and Franks, Paul W and Friedrich, Nele and Gan, Wei and Gandin, Ilaria and Gasparini, Paolo and Giedraitis, Vilmantas and Girotto, Giorgia and Gorski, Mathias and Grallert, Harald and Grarup, Niels and Grove, Megan L and Gustafsson, Stefan and Haessler, Jeff and Hansen, Torben and Hattersley, Andrew T and ... and Cohorts For Heart Aging Res Genomi and EPIC-CVD Consortium and InterAct and Global Lipids Genetic Consortium and GoT2D Genes Consortium and MAGIC Investigators and ReproGen Consortium and T2G Genes Consortium and ExomeBP Consortium and CHD Exome Consortium and CHD Exome+ Consortium and Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium and T2D-Genes Consortium and The MAGIC Investigators
Nature Genetics, ISSN 1061-4036, 03/2019, Volume 51, Issue 3, pp. 452 - 469
Journal Article
by Turcot, Valérie and Lu, Yingchang and Highland, Heather M and Schurmann, Claudia and Justice, Anne E and Fine, Rebecca S and Bradfield, Jonathan P and Esko, Tõnu and Giri, Ayush and Graff, Mariaelisa and Guo, Xiuqing and Hendricks, Audrey E and Karaderi, Tugce and Lempradl, Adelheid and Locke, Adam E and Mahajan, Anubha and Marouli, Eirini and Sivapalaratnam, Suthesh and Young, Kristin L and Alfred, Tamuno and Feitosa, Mary F and Masca, Nicholas G D and Manning, Alisa K and Medina-Gomez, Carolina and Mudgal, Poorva and Ng, Maggie C Y and Reiner, Alex P and Vedantam, Sailaja and Willems, Sara M and Winkler, Thomas W and Abecasis, Gonçalo and Aben, Katja K and Alam, Dewan S and Alharthi, Sameer E and Allison, Matthew and Amouyel, Philippe and Asselbergs, Folkert W and Auer, Paul L and Balkau, Beverley and Bang, Lia E and Barroso, Inês and Bastarache, Lisa and Benn, Marianne and Bergmann, Sven and Bielak, Lawrence F and Blüher, Matthias and Boehnke, Michael and Boeing, Heiner and Boerwinkle, Eric and Böger, Carsten A and Bork-Jensen, Jette and Bots, Michiel L and Bottinger, Erwin P and Bowden, Donald W and Brandslund, Ivan and Breen, Gerome and Brilliant, Murray H and Broer, Linda and Brumat, Marco and Burt, Amber A and Butterworth, Adam S and Campbell, Peter T and Cappellani, Stefania and Carey, David J and Catamo, Eulalia and Caulfield, Mark J and Chambers, John C and Chasman, Daniel I and Chen, Yii-Der I and Chowdhury, Rajiv and Christensen, Cramer and Chu, Audrey Y and Cocca, Massimiliano and Collins, Francis S and Cook, James P and Corley, Janie and Galbany, Jordi Corominas and Cox, Amanda J and Crosslin, David S and Cuellar-Partida, Gabriel and D'Eustacchio, Angela and Danesh, John and Davies, Gail and Bakker, Paul I W and Groot, Mark C H and Mutsert, Renée and Deary, Ian J and Dedoussis, George and Demerath, Ellen W and Heijer, Martin and Hollander, Anneke I and Ruijter, Hester M and Dennis, Joe G and Denny, Josh C and Di Angelantonio, Emanuele and Drenos, Fotios and Du, Mengmeng and Dubé, Marie-Pierre and Dunning, Alison M and Easton, Douglas F and ... and INTERVAL Study and EPIC-CVD Consortium and EPIC InterAct Consortium and Global Lipids Genetic Consortium and CHD Exome+ Consortium and Understanding Society Scientific Group and GoT2D Genes Consortium and MAGIC Investigators and ReproGen Consortium and ExomeBP Consortium and T2D-Genes Consortium and The MAGIC Investigators
Nature genetics, ISSN 1061-4036, 06/2019, Volume 51, Issue 7, pp. 1191 - 1192
An amendment to this paper has been published and can be accessed via a link at the top of the paper. 
Energy intake | Consortia | Body mass index | Genetics | Body mass | Body size
Journal Article
Haematologica, ISSN 0390-6078, 2016, Volume 101, Issue 7, pp. 846 - 852
Journal Article