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science & technology (43) 43
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humans (35) 35
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genetic predisposition to disease (5) 5
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fundamental and applied biological sciences. psychology (3) 3
gastrointestinal agents - administration & dosage (3) 3
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ileum (3) 3
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1. Full Text Seven temperate terrestrial planets around the nearby ultracool dwarf star TRAPPIST-1
by Gillon, Michaël and Triaud, Amaury H. M. J and Demory, Brice-Olivier and Jehin, Emmanuël and Agol, Eric and Deck, Katherine M and Lederer, Susan M and De Wit, Julien and Burdanov, Artem and Ingalls, James G and Bolmont, Emeline and Leconte, Jeremy and Raymond, Sean N and Selsis, Franck and Turbet, Martin and Barkaoui, Khalid and Burgasser, Adam and Burleigh, Matthew R and Carey, Sean J and Chaushev, Aleksander and Copperwheat, Chris M and Delrez, Laetitia and Fernandes, Catarina S and Holdsworth, Daniel L and Kotze, Enrico J and Van Grootel, Valérie and Almleaky, Yaseen and Benkhaldoun, Zouhair and Magain, Pierre and Queloz, Didier
Nature (London), ISSN 0028-0836, 02/2017, Volume 542, Issue 7642, pp. 456 - 460
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Exobiology | Temperature | Planets | Water - analysis | Water - chemistry | Stars, Celestial | Extraterrestrial Environment - chemistry | Terrestrial planets | Discovery and exploration | Extrasolar planets | Earth | Space telescopes | Solar system | Stars & galaxies | Light | Index Medicus | Physics - Earth and Planetary Astrophysics | Earth and Planetary Astrophysics | Sciences of the Universe | Astrophysics
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2. Full Text Induction therapy with the selective interleukin-23 inhibitor risankizumab in patients with moderate-to-severe Crohn's disease: a randomised, double-blind, placebo-controlled phase 2 study
by Feagan, Brian G, Prof and Sandborn, William J, MD and D'Haens, Geert, Prof and Panés, Julián, Prof and Kaser, Arthur, Prof and Ferrante, Marc, Prof and Louis, Edouard, Prof and Franchimont, Denis, Prof and Dewit, Olivier, Prof and Seidler, Ursula, Prof and Kim, Kyung-Jo, Prof and Neurath, Markus F, Prof and Schreiber, Stefan, Prof and Scholl, Paul, MB BChir and Pamulapati, Chandrasena, PhD and Lalovic, Bojan, PhD and Visvanathan, Sudha, PhD and Padula, Steven J, MD and Herichova, Ivona, PhD and Soaita, Adina, PhD and Hall, David B, PhD and Böcher, Wulf O, Prof
The Lancet (British edition), ISSN 0140-6736, 2017, Volume 389, Issue 10080, pp. 1699 - 1709
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Severity of Illness Index | Interleukin-23 Subunit p19 - antagonists & inhibitors | Double-Blind Method | Drug Administration Schedule | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Gastrointestinal Agents - administration & dosage | Antibodies, Monoclonal - therapeutic use | Male | Treatment Outcome | Remission Induction | Dose-Response Relationship, Drug | Young Adult | Antibodies, Monoclonal - administration & dosage | Crohn Disease - drug therapy | Adolescent | Gastrointestinal Agents - therapeutic use | Adult | Female | Aged | Gastrointestinal Agents - adverse effects | Clinical trials | Monoclonal antibodies | Medicine, Experimental | Medical research | Interleukins | Intravenous administration | Pathogenesis | Mucosa | Interleukin | Interleukin 23 | Antagonists | Evidence-based medicine | Intravenous therapy | Randomization | Endoscopes | Motivation | Gastroenterology | Remission | Tumor necrosis factor-TNF | Colon | Safety | Active control | Chronic illnesses | Psoriasis | Cytokines | Ileitis | Nausea | Inflammation | Crohn's disease | Disease control | Patients | Ileum | Crohns disease | Inflammatory bowel disease | Interactive systems | Tumor necrosis factor | Ulcers | TNF inhibitors | Tumors | Index Medicus | Abridged Index Medicus
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3. Full Text Ciclosporin versus infliximab in patients with severe ulcerative colitis refractory to intravenous steroids: a parallel, open-label randomised controlled trial
by Laharie, David, Prof and Bourreille, Arnaud, MD and Branche, Julien, MD and Allez, Matthieu, Prof and Bouhnik, Yoram, Prof and Filippi, Jerome, MD and Zerbib, Frank, Prof and Savoye, Guillaume, Prof and Nachury, Maria, MD and Moreau, Jacques, MD and Delchier, Jean-Charles, Prof and Cosnes, Jacques, Prof and Ricart, Elena, MD and Dewit, Olivier, Prof and Lopez-Sanroman, Antonio, MD and Dupas, Jean-Louis, Prof and Carbonnel, Franck, Prof and Bommelaer, Gilles, Prof and Coffin, Benoit, Prof and Roblin, Xavier, MD and Van Assche, Gert, Prof and Esteve, Maria, MD and Färkkilä, Martti, Prof and Gisbert, Javier P, MD and Marteau, Philippe, Prof and Nahon, Stephane, MD and de Vos, Martine, Prof and Franchimont, Denis, Prof and Mary, Jean-Yves, PhD and Colombel, Jean-Frederic, Prof and Lémann, Marc, Prof and for the Groupe d'Etudes Thérapeutiques des Affections Inflammatoires Digestives and Grp Etud Therapeutiques des Affect and Groupe d'Etudes Thérapeutiques des Affections Inflammatoires Digestives
The Lancet (British edition), ISSN 0140-6736, 2012, Volume 380, Issue 9857, pp. 1909 - 1915
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Gastroenterology. Liver. Pancreas. Abdomen | Stomach. Duodenum. Small intestine. Colon. Rectum. Anus | Biological and medical sciences | General aspects | Medical sciences | Other diseases. Semiology | Steroids - administration & dosage | Acute Disease | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Antibodies, Monoclonal - therapeutic use | Male | Cyclosporine - therapeutic use | Infliximab | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Treatment Failure | Adult | Female | Colitis, Ulcerative - drug therapy | Infusions, Intravenous | Drug Resistance | Complications and side effects | Dosage and administration | Cyclosporine | Research | Drug therapy | Ulcerative colitis | Inflammatory bowel disease | Substance abuse treatment | Heart attacks | Human immunodeficiency virus--HIV | Pharmaceutical industry | Drug resistance | Drug dosages | Steroids | Surgery | Infections | Viral infections | Index Medicus | Abridged Index Medicus | Drugs | International organizations | Side effects | Mortality | Clinical trials | corticoids | Organic chemistry | Chemical Sciences
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4. Full Text Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
by Barrett, Jeffrey C and Hansoul, Sarah and Nicolae, Dan L and Cho, Judy H and Duerr, Richard H and Rioux, John D and Brant, Steven R and Silverberg, Mark S and Taylor, Kent D and Barmada, M Michael and Bitton, Alain and Dassopoulos, Themistocles and Datta, Lisa Wu and Green, Todd and Griffiths, Anne M and Kistner, Emily O and Murtha, Michael T and Regueiro, Miguel D and Rotter, Jerome I and Schumm, L Philip and Steinhart, A Hillary and Targan, Stephan R and Xavier, Ramnik J and Libioulle, Cécile and Sandor, Cynthia and Lathrop, Mark and Belaiche, Jacques and Dewit, Olivier and Gut, Ivo and Heath, Simon and Laukens, Debby and Mni, Myriam and Rutgeerts, Paul and Van Gossum, André and Zelenika, Diana and Franchimont, Denis and Hugot, Jean-Pierre and De Vos, Martine and Vermeire, Severine and Louis, Edouard and Cardon, Lon R and Anderson, Carl A and Drummond, Hazel and Nimmo, Elaine and Ahmad, Tariq and Prescott, Natalie J and Onnie, Clive M and Fisher, Sheila A and Marchini, Jonathan and Ghori, Jilur and Bumpstead, Suzannah and Gwilliam, Rhian and Tremelling, Mark and Deloukas, Panos and Mansfield, John and Jewell, Derek and Satsangi, Jack and Mathew, Christopher G and Parkes, Miles and Georges, Michel and Daly, Mark J and Wellcome Trust Case Control and NIDDK IBD Genetics Consortium and Belgian-French IBD Consortium and Wellcome Trust Case Control Consortium and the NIDDK IBD Genetics Consortium and the Belgian-French IBD Consortium and the Wellcome Trust Case Control Consortium
Nature genetics, ISSN 1061-4036, 2008, Volume 40, Issue 8, pp. 955 - 962
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Gastroenterology. Liver. Pancreas. Abdomen | Stomach. Duodenum. Small intestine. Colon. Rectum. Anus | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | Other diseases. Semiology | Crohn Disease - genetics | Genetic Predisposition to Disease | Genome, Human | Quantitative Trait Loci | Humans | Physiological aspects | Crohn's disease | Genetic aspects | Research | Genetic susceptibility | Risk factors | Inflammatory bowel disease | Studies | Medical research | Genetics | Genomics | Crohns disease | Index Medicus
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5. Full Text Endoscopic improvement of mucosal lesions in patients with moderate to severe ileocolonic Crohn's disease following treatment with certolizumab pegol
by Hébuterne, Xavier and Lémann, Marc and Bouhnik, Yoram and Dewit, Olivier and Dupas, Jean-Louis and Mross, Michael and D'Haens, Geert and Mitchev, Krassimir and Ernault, Étienne and Vermeire, Séverine and Brixi-Benmansour, Hedia and Moreels, Tom G and Mary, Jean-Yves and Marteau, Philippe and Colombel, Jean-Frédéric
Gut, ISSN 0017-5749, 02/2013, Volume 62, Issue 2, pp. 201 - 208
Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Gastroenterology. Liver. Pancreas. Abdomen | Stomach. Duodenum. Small intestine. Colon. Rectum. Anus | Pharmacology. Drug treatments | Bones, joints and connective tissue. Antiinflammatory agents | Biological and medical sciences | Medical sciences | Immunomodulators | Other diseases. Semiology | Severity of Illness Index | Antibodies, Monoclonal, Humanized - adverse effects | Antibodies, Monoclonal, Humanized - therapeutic use | Certolizumab Pegol | Follow-Up Studies | Humans | Immunoglobulin Fab Fragments - adverse effects | Endoscopy, Gastrointestinal | Polyethylene Glycols - adverse effects | Male | Treatment Outcome | Immunoglobulin Fab Fragments - therapeutic use | Polyethylene Glycols - therapeutic use | Remission Induction | Intestinal Mucosa - drug effects | Young Adult | Crohn Disease - drug therapy | Injections, Subcutaneous | Crohn Disease - diagnosis | Adult | Female | Intestinal Mucosa - pathology | Physiological aspects | Care and treatment | Crohn's disease | Research | Patient outcomes | Intestinal mucosa | Bowel disease | Ulcers | Gangrene | Tumor necrosis factor-TNF | Family medical history | Endoscopy | Crohns disease | Index Medicus | Abridged Index Medicus | Certolizumab pegol | anti-TNF agent | endoscopic response | Inflammatory Bowel Disease | 1506 | mucosal healing
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6. Full Text Excess risk of urinary tract cancers in patients receiving thiopurines for inflammatory bowel disease: a prospective observational cohort study
by Bourrier, A and Carrat, F and Colombel, J.‐F and Bouvier, A.‐M and Abitbol, V and Cosnes, J and Peyrin‐Biroulet, L and Beaugerie, L and Gendre, Jean‐Pierre and Lémann, Marc and Hébuterne, Xavier and Bouhnik, Yoram and Laharie, David and Flourié, Bernard and Lerebours, Eric and Cadiot, Guillaume and Soulé, Jean‐Claude and Veyrac, Michel and Duclos, Bernard and Beau, Philippe and Bourreille, Arnaud and Carbonnel, Franck and Heresbach, Denis and Florent, Christian and Blain, Antoine and Faucheron, Jean‐Luc and Bonaz, Bruno and Roblin, Xavier and Potier, Pascal and Kurtz, Thierry and Nion‐Larmurier, Isabelle and Delchier, Jean‐Charles and Chaussade, Stanislas and Weiss, Anne Marie and Cézard, Jean Pierre and Siproudhis, Laurent and Nahon, Stéphane and Sondag, Daniel and Jian, Raymond and Souquet, Jean‐Christophe and Coffin, Benoit and Delasalle, Patrick and Cavicchi, Maryan and Souffran, Marc‐Henry and Vandromme, Luc and Guedon, Claire and Seksik, Philippe and Renard, Pascal and Gouilloud, Sylvie and Savoye, Guillaume and Mallet, Laurent and Brazier, Franck and Justum, Anne‐Marie and Gerbal, Jean‐Luc and Pierrugues, Robert and Chardonnal, Gérard and Picon, Laurence and Reix, Nicole and D'aubigny, Nicolas Drouët and Uettwiller, Hervé and Mallet, Anne Courillon and Palacci, Alain and Bensaude, Raoul‐Jacques and Bonniaud, Pierre and Empinet, Olivier and Nisard, Andrée and Tubiana, Bernard and Capelle, Philippe and Dabadie, Alain and Evard, Daniel and Julien, Pierre‐Emile and Picon‐Coste, Magali and Goldfain, Denis and Blondelot, Jean‐Pierre and Lemière, Sébastien and Mockly, Jean Francois and Pellat, Benoit and Gatineau‐Sailliant, Gilles and Nalet, Bernard and Nancey, Stéphane and Kusielewicz, Daniel and Loison, Patrick and Merite, François and Roux, Jean‐Pol and Blanquart, Alain and Heyries, Laurent and Reville, Marc and Zerbib, Frank and Claviere, Christophe and Pouderoux, Philippe and Moitry, Alain and Hugot, Jean‐Pierre and Sabate, Jean‐Marc and Lescut, Dominique and Smadja, Lionel and Steinberg, Michel and Brun, Marc and Macaigne, Gilles and Marchal, Jean Luc and Ollivier, Stéphane and ... and CESAME Study Grp and CESAME study group and the CESAME study group
Alimentary pharmacology & therapeutics, ISSN 0269-2813, 01/2016, Volume 43, Issue 2, pp. 252 - 261
Gastroenterology & Hepatology | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Science & Technology | Inflammatory Bowel Diseases - drug therapy | Urologic Neoplasms - epidemiology | Prospective Studies | Humans | Middle Aged | Risk Factors | Urologic Neoplasms - etiology | Proportional Hazards Models | Male | Incidence | Young Adult | Adult | Female | Cohort Studies | Inflammatory bowel diseases | Kidneys | Health risks | Bladder | Urinary tract | Risk analysis | Patients | Risk factors | Inflammatory bowel disease | Intestine | Health risk assessment | Urogenital system | Cancer | Index Medicus | Life Sciences | Microbiology and Parasitology | Molecular biology | Biochemistry, Molecular Biology | Bacteriology
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7. Full Text Mesalamine Foam Enema Versus Mesalamine Liquid Enema in Active Left-Sided Ulcerative Colitis
by Cortot, Antoine and Maetz, Denis and Degoutte, Eric and Delette, Olivier and Meunier, Pierre and Tan, Gie and Cazals, Jean-Brice and Dewit, Olivier and Hebuterne, Xavier and Beorchia, Sylvain and Grunberg, Bernard and Leprince, Eric and D'Haens, Geert and Forestier, Sylvie and Idier, Isabelle and Lemann, Marc
The American journal of gastroenterology, ISSN 0002-9270, 12/2008, Volume 103, Issue 12, pp. 3106 - 3114
Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Gastroenterology. Liver. Pancreas. Abdomen | Stomach. Duodenum. Small intestine. Colon. Rectum. Anus | Pharmacology. Drug treatments | Bones, joints and connective tissue. Antiinflammatory agents | Biological and medical sciences | Medical sciences | Other diseases. Semiology | Single-Blind Method | Colitis, Ulcerative - complications | Humans | Middle Aged | Proctitis - drug therapy | Proctocolitis - drug therapy | Administration, Rectal | Male | Treatment Outcome | Young Adult | Proctitis - etiology | Enema - methods | Adolescent | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Aged, 80 and over | Proctocolitis - etiology | Adult | Female | Aged | Colitis, Ulcerative - drug therapy | Dosage Forms | Mesalamine - administration & dosage | Mesalamine | Antifungal agents | Ulcerative colitis | Index Medicus
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