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Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 02/2016, Volume 60, Issue 2, pp. 904 - 912
ABSTRACTBroadly neutralizing monoclonal antibodies (nAbs) specific for HIV are being investigated for use in HIV prevention. Due to their ability to inhibit... 
Journal Article
AIDS Research and Human Retroviruses, ISSN 0889-2229, 10/2014, Volume 30, Issue S1, pp. A78 - A78
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2010, Volume 5, Issue 2, p. e9310
Background: Tenofovir gel has entered into clinical trials for use as a topical microbicide to prevent HIV-1 infection but has no published data regarding... 
TOPICAL MICROBICIDES | SOUTH-AFRICA | MULTIDISCIPLINARY SCIENCES | FEMALE SEX WORKERS | CLINICAL-TRIALS | NONOXYNOL-9 VAGINAL GEL | DOUBLE-BLIND | NEISSERIA-GONORRHOEAE | RECTAL TRANSMISSION | EXPLANT CULTURE | PLACEBO-CONTROLLED TRIAL | Anti-HIV Agents - pharmacology | Colon - cytology | Humans | Colon - drug effects | Leukocytes, Mononuclear - virology | Rectum - virology | Tenofovir | HIV-1 - growth & development | Rectum - drug effects | Female | Colon - virology | Drug Evaluation, Preclinical | Caco-2 Cells | Cervix Uteri - drug effects | Cell Survival - drug effects | Adenine - analogs & derivatives | Leukocytes, Mononuclear - drug effects | Cervix Uteri - virology | Gels | HIV-1 - drug effects | Tissue Culture Techniques | Cells, Cultured | Adenine - pharmacology | Organophosphonates - pharmacology | Rectum - cytology | Leukocytes, Mononuclear - cytology | Cervix Uteri - cytology | Infection | Medical research | Algorithms | Microbiota (Symbiotic organisms) | Analysis | Medicine, Experimental | Permeability | HIV (Viruses) | Health aspects | Enzyme-linked immunosorbent assay | Viscosity | Immunohistochemistry | Epithelial cells | Prophylaxis | Clinical trials | Infections | Tissues | Prevention | Genital microflora | Microbicides | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Safety | Explants | Effectiveness | Computer simulation | Vagina | Cultures | Data processing | Flora | Condoms | Osmotic pressure | Viability | Acquired immune deficiency syndrome | AIDS | HIV | Human immunodeficiency virus
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2012, Volume 7, Issue 11, p. e48328
Because lubricants may decrease trauma during coitus, it is hypothesized that they could aid in the prevention of HIV acquisition. Therefore, safety and... 
HERPES-SIMPLEX-VIRUS | HIV-INFECTION | SODIUM-SALICYLATE | MULTIDISCIPLINARY SCIENCES | CANDIDATE TOPICAL MICROBICIDES | VAGINAL MICROBICIDE | PHASE-I SAFETY | CELLULOSE SULFATE GEL | EPIGALLOCATECHIN GALLATE | HUMAN-IMMUNODEFICIENCY-VIRUS | SEXUAL TRANSMISSION | Anti-HIV Agents - pharmacology | Viscosity | HIV Infections - prevention & control | Epithelial Cells - drug effects | Humans | Phosphates - chemistry | Nonprescription Drugs | Lubricants - pharmacology | Epithelial Cells - physiology | Cellulose - chemistry | Osmolar Concentration | Lactobacillus - drug effects | Female | Glycerol - pharmacology | Mucous Membrane - drug effects | Glycerol - chemistry | Phosphates - pharmacology | Cellulose - analogs & derivatives | Propylene Glycols - pharmacology | Cell Line | Cell Survival - drug effects | Microbial Viability - drug effects | Mucous Membrane - virology | HIV-1 - drug effects | Lubricants - chemistry | Anti-HIV Agents - chemistry | Mucous Membrane - pathology | Propylene Glycols - chemistry | Silicone Gels | Spermatocidal Agents - pharmacology | Spermatocidal Agents - chemistry | Cellulose - pharmacology | HIV (Viruses) | Lubrication and lubricants | Nonprescription drugs | Evaluation | Gels | Lubricants | Toxicity | Epithelial cells | Mucosa | Sexual intercourse | Tissues | Trauma | Nonoxynol | Disease transmission | Acquired immune deficiency syndrome--AIDS | Platinum | Human immunodeficiency virus--HIV | Cell lines | Antiviral activity | Safety | Condoms | Osmotic pressure | Silicones | Viability | Rheological properties | AIDS | HIV | Acquired immune deficiency syndrome | Human immunodeficiency virus
Journal Article
JAIDS Journal of Acquired Immune Deficiency Syndromes, ISSN 1525-4135, 11/2015, Volume 70, Issue 3, pp. 242 - 249
Journal Article
Pharmaceutical Research, ISSN 0724-8741, 3/2009, Volume 26, Issue 3, pp. 502 - 511
Nanoparticles formulated from the biodegradable co-polymer poly(lactic-co-glycolic acid) (PLGA), were investigated as a drug delivery system to enhance tissue... 
Biomedical Engineering | Biochemistry, general | HIV-1 prevention | PSC-RANTES | Biomedicine | microbicide | nanoparticles | Pharmacy | Medical Law | drug delivery | Pharmacology/Toxicology | Nanoparticles | Microbicide | Drug delivery | ENTRY INHIBITORS | MOLECULAR-WEIGHT | MICROSPHERES | DRUG-DELIVERY | CONTROLLED-RELEASE | HUMAN-IMMUNODEFICIENCY-VIRUS | CHEMISTRY, MULTIDISCIPLINARY | LANGERHANS CELLS | TRANSMISSION | IN-VIVO | PHARMACOLOGY & PHARMACY | PLGA NANOPARTICLES | HIV Infections - prevention & control | Cervix Uteri - metabolism | Nanoparticles - chemistry | Biocompatible Materials - chemistry | Humans | Middle Aged | Drug Carriers - chemistry | Antimicrobial Cationic Peptides - pharmacokinetics | HIV Fusion Inhibitors - administration & dosage | Surface Properties | Adult | Chemokine CCL5 - pharmacokinetics | Female | Antimicrobial Cationic Peptides - chemistry | Chemokine CCL5 - administration & dosage | HIV-1 - drug effects | HIV Infections - virology | Solubility | Permeability | HIV Fusion Inhibitors - pharmacology | Chemokine CCL5 - pharmacology | HIV Fusion Inhibitors - pharmacokinetics | Drug Carriers - pharmacokinetics | Virus Cultivation | Biocompatible Materials - pharmacokinetics | HeLa Cells | In Vitro Techniques | Cervix Uteri - cytology | Prevention | Drugs | Drug delivery systems | Analysis | HIV (Viruses) | Vehicles | Disease prevention | Biodegradable materials | Prescription drugs | Human immunodeficiency virus--HIV | Pharmaceutical sciences
Journal Article
PLoS Medicine, ISSN 1549-1277, 08/2008, Volume 5, Issue 8
  [...]the authors adapted an in vitro human rectal explant model (tissues taken from the rectum are kept alive and challenged with virus in culture) to... 
Studies | Plasma | Animals | Lymphocytes | Human immunodeficiency virus--HIV | Drug dosages
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2018, Volume 13, Issue 6, p. e0199778
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2015, Volume 10, Issue 5, p. e0125363
Objectives The CHARM-01 study characterized the safety, acceptability, pharmacokinetics (PK), and pharmacodynamics (PD) of three tenofovir (TFV) gels for... 
TRIALS | AFRICAN WOMEN | ORAL TENOFOVIR | HIV-INFECTION | MICROBICIDE | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | TISSUE | PREEXPOSURE PROPHYLAXIS | Anti-HIV Agents - pharmacology | T-Lymphocyte Subsets - immunology | Rectum - pathology | Humans | Middle Aged | Tenofovir - pharmacology | Anti-Infective Agents, Local - adverse effects | Male | Tenofovir - administration & dosage | Intestinal Mucosa - drug effects | Anti-HIV Agents - administration & dosage | Young Adult | HIV Infections - immunology | Microbiota | Intestinal Mucosa - immunology | T-Lymphocyte Subsets - drug effects | Adult | Female | Tenofovir - adverse effects | Gels | Anti-Infective Agents, Local - pharmacology | Anti-HIV Agents - adverse effects | HIV Infections - virology | Immunophenotyping | Treatment Outcome | Intestinal Mucosa - microbiology | Chemistry, Pharmaceutical | Medication Adherence | Phenotype | Anti-Infective Agents, Local - administration & dosage | T-Lymphocyte Subsets - metabolism | HIV Infections - drug therapy | Intestinal Mucosa - pathology | Tenofovir | Patient outcomes | Economic aspects | Dosage and administration | Research | Drug therapy | HIV infection | Formulations | Pharmacodynamics | Mucosa | Vagina | Infections | Pharmacology | Acceptability | Disease prevention | Medicine | Mens health | Randomization | Acquired immune deficiency syndrome--AIDS | Safety engineering | Human immunodeficiency virus--HIV | Rectum | Safety | Inhibition | Transgender persons | Pharmacokinetics | Drug dosages | AIDS | HIV | Acquired immune deficiency syndrome | Human immunodeficiency virus
Journal Article
Journal of Antimicrobial Chemotherapy, ISSN 0305-7453, 09/2012, Volume 67, Issue 9, pp. 2139 - 2142
Journal Article