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PLoS ONE, ISSN 1932-6203, 09/2014, Volume 9, Issue 9, p. e108890
... Vishnu M. Dhople Affiliation: Interfacultary Institute of Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany Uwe Völker... 
COA REDUCTASE | LOVASTATIN | APOPTOSIS | SIP1 | INHIBITION | VIMENTIN | MULTIDISCIPLINARY SCIENCES | NITRIC-OXIDE | STATINS | EXPRESSION | BINDING | Mevalonic Acid - pharmacology | Anticholesteremic Agents - toxicity | Apoptosis - drug effects | Vimentin - metabolism | Caspase 3 - chemistry | Humans | Caspase 3 - metabolism | Electrophoresis, Gel, Two-Dimensional | Epithelial-Mesenchymal Transition - drug effects | Indoles - toxicity | Chromatography, High Pressure Liquid | Proteome - analysis | Breast Neoplasms | Tandem Mass Spectrometry | Metabolic Networks and Pathways | Cell Line, Tumor | Female | Fatty Acids, Monounsaturated - toxicity | Acyl Coenzyme A - metabolism | Mitogen-Activated Protein Kinase 1 - metabolism | Fluvastatin | Proteolysis | Cell death | Breast cancer | Biochemistry | Intermediate filament proteins | Antilipemic agents | Vimentin | Phosphorylation | Motility | Mesenchyme | Epithelial cells | Downstream effects | Genomics | Biosynthesis | Biology | Kinases | Caspase-3 | Anticancer properties | Metastases | Proteins | Signal transduction | Mevalonic acid | Pathways | Cell cycle | Spots | Mammary gland | Statins | Sensitivity analysis | Mortality | Extracellular signal-regulated kinase | Caspase | Metabolism | Signaling | Proteasomes | Cytoskeleton | Cholera | Prostate cancer | Cancer | Apoptosis
Journal Article
Journal Article
PLOS PATHOGENS, ISSN 1553-7366, 07/2019, Volume 15, Issue 7, p. e1007987
Streptococcus pneumoniae (pneumococci) is a leading cause of severe bacterial meningitis in many countries worldwide. To characterize the repertoire of fitness... 
PEPTIDE IDENTIFICATION | GENOMIC ANALYSIS | MICROBIOLOGY | CEREBROSPINAL-FLUID | VIRULENCE | PNEUMOLYSIN | STREPTOCOCCUS-PNEUMONIAE | BACTERIAL-MENINGITIS | VIROLOGY | DISEASE | STRESS | GENETIC-TRANSFORMATION | PARASITOLOGY | Lipoproteins - deficiency | Meningitis, Pneumococcal - microbiology | Virulence Factors - genetics | Virulence Factors - physiology | Lipoproteins - genetics | Humans | Male | Regulon | Host Microbial Interactions - physiology | Streptococcus pneumoniae - pathogenicity | Virulence - genetics | Streptococcus pneumoniae - genetics | Streptococcus pneumoniae - physiology | Carrier Proteins - physiology | Meningitis, Pneumococcal - cerebrospinal fluid | Genes, Bacterial | Mice, Inbred C57BL | Bacterial Proteins - genetics | Bacterial Proteins - physiology | Lipoproteins - physiology | Carrier Proteins - genetics | Animals | Proteomics | Virulence - physiology | Mice | Mutation | Care and treatment | Usage | Bacterial meningitis | Research | Cerebrospinal fluid | Health aspects | Mass spectrometry | Risk factors | Protein binding | Genomics | Virulence | Biology | Streptococcus infections | Proteins | Virulence factors | Genetics | Meningitis | Bacteria | Supervision | Adaptation | Pathogens | Antigens | Bacterial infections | Mass spectroscopy | Gene expression | Substrates | Medicine | Antibiotics | Brain damage | Transporter | Niches | Fitness
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 37, pp. 15205 - 15215
Transcriptional activation of the human telomerase reverse transcriptase (hTERT) gene, which remains repressed in adult somatic cells, is critical during... 
CELLS | ACTIVATION | NM23-H2 | DNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | TRANSCRIPTION | GENE-EXPRESSION | HUMAN CANCERS | PROMOTER | GENOME | Epigenetic Repression | Humans | Protein Multimerization | Neoplasm Proteins - antagonists & inhibitors | Fibrosarcoma - metabolism | Neoplasm Proteins - metabolism | NM23 Nucleoside Diphosphate Kinases - genetics | NM23 Nucleoside Diphosphate Kinases - metabolism | Repressor Proteins - antagonists & inhibitors | Fibrosarcoma - pathology | Telomerase - genetics | Chromatin Immunoprecipitation | RNA Interference | Carcinoma - enzymology | G-Quadruplexes | Telomerase - metabolism | Carcinoma - pathology | Neoplasm Proteins - genetics | Genes, Reporter | Repressor Proteins - metabolism | Recombinant Proteins - metabolism | NM23 Nucleoside Diphosphate Kinases - chemistry | Promoter Regions, Genetic | Repressor Proteins - chemistry | Mutagenesis, Site-Directed | Histone Demethylases - chemistry | NM23 Nucleoside Diphosphate Kinases - antagonists & inhibitors | Cells, Cultured | Recombinant Proteins - chemistry | Repressor Proteins - genetics | Neoplasm Proteins - chemistry | Histone Demethylases - metabolism | Point Mutation | Cell Line, Tumor | Carcinoma - metabolism | Telomerase - antagonists & inhibitors | Fibrosarcoma - enzymology | Amino Acid Substitution | Gene Regulation | transcription regulation | chromatin modification | G-quadruplex | telomerase reverse transcriptase (TERT) | NME2 | REST repressor complex | epigenetics
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2015, Volume 10, Issue 3, p. e0120360
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2018, Volume 293, Issue 48, pp. 18477 - 18493
Frizzleds (FZDs) are receptors for secreted lipoglycoproteins of the Wingless/Int-1(WNT) family, initiating an important signal transduction network in... 
RECRUITMENT | COMPLEX | DEP DOMAIN | BETA-ARRESTINS | BIOCHEMISTRY & MOLECULAR BIOLOGY | GROWTH | FUNCTIONAL-ANALYSIS | I-EPSILON | RECEPTOR | DIX DOMAIN | PLANAR POLARITY | serine | GRK | Signal Transduction | receptor regulation | casein kinase 1 | Dishevelled | cell signaling | G protein-coupled receptor (GPCR) | threonine protein kinase | scaffold protein | cell polarity | Frizzled | WNT | phosphorylation
Journal Article
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 03/2019, Volume 119, Issue 3, pp. 407 - 420
Abstract Epidemiological studies found an association between increased platelet size and the risk for thrombotic complications, but functional differences of... 
Cellular Haemostasis and Platelets | platelet function | platelet physiology | platelet size | HETEROGENEITY | RATIO | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY
Journal Article
Data in Brief, ISSN 2352-3409, 10/2017, Volume 14, Issue C, pp. 313 - 319
Complete blood protein profiles of 4 different blood sample collection methods (EDTA-, heparin- and citrate plasma and serum) were investigated and the data... 
Plasma | Serum | LC-MSE method data | Proteomics | method data | LC-MS
Journal Article
Data in Brief, ISSN 2352-3409, 06/2016, Volume 7, pp. 1031 - 1037
To simultaneously obtain proteome data of host and pathogen from an internalization experiment, human alveolar epithelial A549 cells were infected with... 
Flow cytometry | Epithelial cells | Internalization | Proteomics | SILAC | Host-pathogen interaction | Staphylococcus aureus
Journal Article