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Neuron, ISSN 0896-6273, 02/2013, Volume 77, Issue 3, pp. 425 - 439
Recent genome-wide association studies have linked common variants in the human genome to Parkinson@s disease (PD) risk. Here we show that the consequences of... 
LOCALIZATION | RETROMER | TRANSPORT | ELEGANS | GENE-EXPRESSION | TRAFFICKING | ALPHA | NEURODEGENERATION | MICE | NEUROSCIENCES | DROSOPHILA | rab5 GTP-Binding Proteins - genetics | Immunoprecipitation | Humans | Middle Aged | Cerebral Cortex - pathology | Male | Tubulin - genetics | rab GTP-Binding Proteins - genetics | Green Fluorescent Proteins - genetics | Statistics as Topic | Vesicle-Associated Membrane Protein 2 - genetics | Cerebral Cortex - cytology | Tyrosine 3-Monooxygenase | rab5 GTP-Binding Proteins - metabolism | Tubulin - metabolism | Transfection | Aged, 80 and over | Female | Neurons - metabolism | Parkinson Disease - metabolism | Protein-Serine-Threonine Kinases - metabolism | Animals, Newborn | Synaptosomal-Associated Protein 25 - genetics | rab GTP-Binding Proteins - metabolism | Genetic Predisposition to Disease | Genome-Wide Association Study | Parkinson Disease - pathology | Animals, Genetically Modified | Drosophila | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Rats | Parkinson Disease - genetics | Mutation - genetics | Rats, Sprague-Dawley | Protein Transport - genetics | Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 | Animals | Polymorphism, Single Nucleotide - genetics | Aged | Mice | Synaptosomal-Associated Protein 25 - metabolism | Vesicle-Associated Membrane Protein 2 - metabolism | Parkinson's disease | Neurons | Genomics | Risk factors | Brain | Laboratories | Parkinsons disease | Kinases | Gene expression | Experiments | Defects | Proteins | Pathology | Insects | Neurodegeneration | Gene loci | Mutation | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 09/2004, Volume 431, Issue 7007, pp. 415 - 422
Phosphatidylinositol-4,5-bisphosphate (PtdIns(4,5) P-2) has an important function in cell regulation both as a precursor of second messenger molecules and by... 
TRANSMITTER RELEASE | TRANSMISSION | DOMAIN | MULTIDISCIPLINARY SCIENCES | POOL | I-GAMMA | ENDOCYTOSIS | PLASMA-MEMBRANE | CLATHRIN | HIPPOCAMPAL SYNAPSES | ARF6
Journal Article
ISSN 0027-8424, 2017
Membrane phase behavior has been well characterized in model membranes in vitro under thermodynamic equilibrium state. However, the widely observed differences... 
Lipids--Metabolism | Cell membranes | Biophysics | Molecular biology | Endoplasmic reticulum
Journal Article
2012, 1st ed., Methods in cell biology, ISBN 0123864879, Volume 108.
Web Resource
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 48, pp. 19873 - 19889
Journal Article
Neuron, ISSN 0896-6273, 03/2013, Volume 77, Issue 5, pp. 801 - 803
In this issue of , report on the production of toxic lipids by Schwann cells deficient in mitochondrial respiration, which are capable of destroying... 
METABOLISM | NEUROSCIENCES | Lipids | Neurosciences | Mitochondrial DNA | Alzheimer's disease | Cells | Amyloid beta-protein | Studies | Medical research | Kinases
Journal Article
Proceedings of the National Academy of Sciences of the United States, ISSN 0027-8424, 12/2017, Volume 114, Issue 51, p. 13394
Membrane phase behavior has been well characterized in model membranes in vitro under thermodynamic equilibrium state. However, the widely observed differences... 
Physiological aspects | Endoplasmic reticulum | Membrane proteins
Journal Article
ISSN 1932-6203, 2017
Parkinson’s disease (PD) is a common neurodegenerative disease whose pathological hallmark is the accumulation of intracellular α-synuclein aggregates in Lewy... 
Medicine | Neurosciences | Parkinson's disease | Parkinson's disease--Pathophysiology | Nervous system--Degeneration
Journal Article
Nature Reviews Neuroscience, ISSN 1471-003X, 08/2011, Volume 12, Issue 8, pp. 484 - 484
Journal Article
Nature Reviews Neuroscience, ISSN 1471-003X, 05/2011, Volume 12, Issue 5, p. 284
Journal Article
by Klionsky, Daniel J and Abdalla, Fabio C and Abeliovich, Hagai and Abraham, Robert T and Acevedo-Arozena, Abraham and Adeli, Khosrow and Agholme, Lotta and Agnello, Maria and Agostinis, Patrizia and Aguirre-Ghiso, Julio A and Ahn, Hyung Jun and Ait-Mohamed, Ouardia and Ait-Si-Ali, Slimane and Akematsu, Takahiko and Akira, Shizuo and Al-Younes, Hesham M and Al-Zeer, Munir A and Albert, Matthew L and Albin, Roger L and Alegre-Abarrategui, Javier and Aleo, Maria Francesca and Alirezaei, Mehrdad and Almasan, Alexandru and Almonte-Becerril, Maylin and Amano, Atsuo and Amaravadi, Ravi K and Amarnath, Shoba and Amer, Amal O and Andrieu-Abadie, Nathalie and Anantharam, Vellareddy and Ann, David K and Anoopkumar-Dukie, Shailendra and Aoki, Hiroshi and Apostolova, Nadezda and Arancia, Giuseppe and Aris, John P and Asanuma, Katsuhiko and Asare, Nana Y.O and Ashida, Hisashi and Askanas, Valerie and Askew, David S and Auberger, Patrick and Baba, Misuzu and Backues, Steven K and Baehrecke, Eric H and Bahr, Ben A and Bai, Xue-Yuan and Bailly, Yannick and Baiocchi, Robert and Baldini, Giulia and Balduini, Walter and Ballabio, Andrea and Bamber, Bruce A and Bampton, Edward T.W and Juhász, Gábor and Bartholomew, Clinton R and Bassham, Diane C and Bast, Robert C and Batoko, Henri and Bay, Boon-Huat and Beau, Isabelle and Béchet, Daniel M and Begley, Thomas J and Behl, Christian and Behrends, Christian and Bekri, Soumeya and Bellaire, Bryan and Bendall, Linda J and Benetti, Luca and Berliocchi, Laura and Bernardi, Henri and Bernassola, Francesca and Besteiro, Sébastien and Bhatia-Kissova, Ingrid and Bi, Xiaoning and Biard-Piechaczyk, Martine and Blum, Janice S and Boise, Lawrence H and Bonaldo, Paolo and Boone, David L and Bornhauser, Beat C and Bortoluci, Karina R and Bossis, Ioannis and Bost, Frédéric and Bourquin, Jean-Pierre and Boya, Patricia and Boyer-Guittaut, Michaël and Bozhkov, Peter V and Brady, Nathan R and Brancolini, Claudio and Brech, Andreas and Brenman, Jay E and Brennand, Ana and Bresnick, Emery H and Brest, Patrick and Bridges, Dave and Bristol, Molly L and Brookes, Paul S and Brown, Eric J and Brumell, John H and ... and Linköpings universitet and Institutionen för klinisk och experimentell medicin and Geriatrik and Institutionen för medicin och hälsa and Farmakologi and Experimentell patologi and Hälsouniversitetet and Cellbiologi
Autophagy, ISSN 1554-8627, 04/2012, Volume 8, Issue 4, pp. 445 - 544
Journal Article
ISSN 1932-6203, 2015
Objective Variants in GBA are associated with Lewy Body (LB) pathology. We investigated whether variants in other lysosomal storage disorder (LSD) genes also... 
Nervous system--Diseases | Neurology | Pathology | Lysosomal storage diseases | Biochemistry | Bioinformatics
Journal Article
ISSN 1932-6203, 2013
Synthesis of phosphatidylinositol-3-phosphate (PI3P) by Vps34, a class III phosphatidylinositol 3-kinase (PI3K), is critical for the initial steps of... 
Proteins--Biodegradation | Protein kinases--Physiological effect | Fibroblasts | Molecular biology
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 01/2013, Volume 288, Issue 3, pp. 1856 - 1870
The accumulation of Tau into aggregates is associated with key pathological events in frontotemporal lobe degeneration (FTD-Tau) and Alzheimer disease (AD).... 
EXTRACELLULAR ALPHA-SYNUCLEIN | IN-VITRO | PRION DISEASES | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY |