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GENOME MEDICINE, ISSN 1756-994X, 06/2019, Volume 11, Issue 1, pp. 42 - 22
BackgroundNeoantigens that arise as a consequence of tumor-specific mutations can be recognized by T lymphocytes leading to effective immune surveillance. In... 
HUMAN COLON | MUTATIONAL SIGNATURES | DRUG-SENSITIVITY | Immune response | Mutational signature | MICROSATELLITE INSTABILITY | Colorectal cancer | DNA repair | GENOMIC LANDSCAPE | EVOLUTION | GENETICS & HEREDITY | RESISTANCE | GENERATION | EGFR BLOCKADE | Neoantigen | XENOGRAFTS | Antigens | Care and treatment | Cancer patients | Gene mutations | Genetic aspects | Research | Health aspects
Journal Article
Clinical cancer research : an official journal of the American Association for Cancer Research, ISSN 1078-0432, 08/2019, Volume 25, Issue 20, pp. 6243 - 6259
Patient-derived xenograft (PDX) models accurately recapitulate the tumor of origin in terms of histopathology, genomic landscape, and therapeutic response, but... 
Journal Article
Clinical Colorectal Cancer, ISSN 1533-0028, 06/2019, Volume 18, Issue 2, pp. 91 - 101.e3
The diagnosis of colorectal cancer (CRC) is routinely accomplished through histopathologic examination. Prognostic information and treatment decisions are... 
IDEA | Bioinformatics | Next generation sequencing | Colorectal cancer | Genetic alterations | Genetic aspects | Prognosis | Research | Gene mutations
Journal Article
Molecular Oncology, ISSN 1574-7891, 04/2019, Volume 13, Issue 4, pp. 681 - 700
Colorectal cancer (CRC) is the third leading cause of cancer‐related deaths worldwide. Therapies that take advantage of defects in DNA repair pathways have... 
microsatellite instability | mismatch repair | colorectal cancer | genome instability | homologous recombination | MISMATCH-REPAIR | SINGLE-STRANDED-DNA | OVARIAN-CANCER | PARP INHIBITOR ABT-888 | HOMOLOGOUS RECOMBINATION REPAIR | DAMAGE RESPONSE | IN-VITRO | ONCOLOGY | ATM DEFICIENCY | MLH1 PROMOTER HYPERMETHYLATION | Review
Journal Article
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2287 - 12
Journal Article
Gut, ISSN 0017-5749, 11/2018, Volume 67, Issue 11, pp. 1995 - 2005
Journal Article
International Journal of Cancer, ISSN 0020-7136, 08/2018, Volume 143, Issue 4, pp. 907 - 920
Journal Article