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PLoS computational biology, ISSN 1553-734X, 08/2019, Volume 15, Issue 8, pp. e1007266 - e1007266
During thrombosis, thrombin generates fibrin, however fibrin reversibly binds thrombin with low affinity E-domain sites (KD = 2.8 μM) and high affinity... 
Index Medicus
Journal Article
Cell, ISSN 0092-8674, 03/2017, Volume 169, Issue 1, p. 176
(Cell 168, 1114–1125; March 9, 2017) Our paper describes a modified mRNA vaccine that protects rodents against Zika virus infection. In the version originally... 
Journal Article
PLoS Computational Biology, ISSN 1553-734X, 02/2015, Volume 11, Issue 2
  Since platelet intracellular calcium mobilization [Ca(t)]i controls granule release, cyclooxygenase-1 and integrin activation, and phosphatidylserine... 
Datasets | Blood platelets | Calcium | Neural networks | Nitric oxide | Collagen | Experiments
Journal Article
Biomechanics and modeling in mechanobiology, ISSN 1617-7959, 05/2019, pp. 1 - 14
The ability of a blood clot to modulate blood flow is determined by the clot's resistance, which depends on its structural features. For a flow with arterial... 
Blood coagulation | Shear flow | Tissue factor | Thrombin | Blood | Blood platelets | Deposition | Axial flow | Bulk density | Fluid dynamics | Computer simulation | Computational fluid dynamics | Hydrodynamics | Flow resistance | Calibration | Velocity | Blood flow | Fibrin | Collagen | Computer applications | Flow velocity | Kinetics | Variation | Platelets | Microfluidics
Journal Article
Blood, ISSN 0006-4971, 11/2008, Volume 112, Issue 10, pp. 4069 - 4079
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 09/2017, Volume 37, Issue 9, pp. 1595 - 1595
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2005, Volume 102, Issue 33, pp. 11876 - 11881
Journal Article
Biophysical Journal, ISSN 0006-3495, 05/2014, Volume 106, Issue 9, p. 2049
Resting platelets maintain a stable level of low cytoplasmic calcium ([Ca.sup.2+].sub.cyt) and high dense tubular system calcium ([Ca.sup.2+].sub.dts). During... 
Monte Carlo method | Inositol | Calcium channels | Analysis | Homeostasis | Models | Adenosine triphosphatase
Journal Article
Biophysical Journal, ISSN 0006-3495, 05/2014, Volume 106, Issue 9, p. 2049
  Resting platelets maintain a stable level of low cytoplasmic calcium ([Ca^sup 2+^]^sub cyt^) and high dense tubular system calcium ([Ca^sup 2+^]^sub dts^).... 
Blood platelets | Calcium | Reaction kinetics | Biochemistry | Thrombosis | Cytoplasm
Journal Article
ISSN 1757-9694, 8/2016, Volume 8, Issue 8, pp. 813 - 82
It is unknown if a lower size limit exists for human blood coagulation under flow over physiological vessel wall triggers as small as a single collagen fiber.... 
Journal Article
Thrombosis Research, ISSN 0049-3848, 02/2014, Volume 133, Issue 2, p. 203
Microfluidic devices recreate the hemodynamic conditions of thrombosis. 
Journal Article
Biophysical Journal, ISSN 0006-3495, 06/2014, Volume 106, Issue 11, pp. 2529 - 2540
A high-fidelity computational model using a 3D immersed boundary method is used to study platelet dynamics in whole blood. We focus on the 3D effects of the... 
TRANSPORT | MOTION | BIOPHYSICS | LATERAL MIGRATION | ERYTHROCYTES | SHEAR-FLOW | FLOWING BLOOD | SIZED PARTICLES | MECHANISMS | NEAR-WALL EXCESS | VESSEL WALL | Animals | Models, Cardiovascular | Humans | Erythrocytes - physiology | Blood Platelets - physiology | Hemorheology | Cell Adhesion | Anisotropy | Analysis | Aerospace engineering | Biophysics | Blood platelets | Erythrocytes | Index Medicus | Systems Biophysics
Journal Article
ISSN 1473-0197, 4/2013, Volume 13, Issue 1, pp. 1883 - 1891
Hemodynamic conditions vary throughout the vasculature, creating diverse environments in which platelets must respond. To stop bleeding, a growing platelet... 
Journal Article
Journal of thrombosis and haemostasis : JTH, ISSN 1538-7933, 5/2016, Volume 14, Issue 5, pp. 906 - 917
The biophysics of blood flow can dictate the function of molecules and cells in the vasculature with consequent effects on haemostasis, thrombosis, embolism,... 
platelet | shear stress | thrombin | von Willebrand Factor | fibrin | haemodynamics
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 04/2019, Volume 119, Issue 4, pp. 586 - 593
Abstract Neutrophils can release extracellular traps (NETs) in infectious, inflammatory and thrombotic diseases. NETs have been detected in deep vein... 
Coagulation and Fibrinolysis | extracellular traps | platelet | fibrin | neutrophil | haemodynamics | ACTIVATION | BACTERIA | VENOUS THROMBOSIS | NEUTROPHIL EXTRACELLULAR TRAPS | PLATELETS | DNA | CLOTS | COAGULATION | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | CAPTURE
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Journal Article
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