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1. Full Text Sex-associated molecular differences for cancer immunotherapy
by Ye, Youqiong and Jing, Ying and Li, Liang and Mills, Gordon B and Diao, Lixia and Liu, Hong and Han, Leng
Nature communications, ISSN 2041-1723, 04/2020, Volume 11, Issue 1, pp. 1779 - 1779
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Profiling | Immune checkpoint | Reviews | Immunotherapy | Lung cancer | Melanoma | Sex | Clinical trials | Genomes | Gender | Cancer | Index Medicus
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2. Full Text TANRIC: An Interactive Open Platform to Explore the Function of lncRNAs in Cancer
by Li, Jun and Han, Leng and Roebuck, Paul and Diao, Lixia and Liu, Lingxiang and Yuan, Yuan and Weinstein, John N and Liang, Han
Cancer research (Chicago, Ill.), ISSN 0008-5472, 09/2015, Volume 75, Issue 18, pp. 3728 - 3737
Life Sciences & Biomedicine | Oncology | Science & Technology | User-Computer Interface | Algorithms | Neoplasms - genetics | Humans | Cell Line, Tumor | Databases, Genetic | Gene Expression Profiling | RNA, Long Noncoding - genetics | Software | Internet | Index Medicus | lncRNA expression | cancer genomics | prognostic marker | bioinformatics resource | TCGA
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3. Full Text Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression
by Chen, Limo and Gibbons, Don L and Goswami, Sangeeta and Cortez, Maria Angelica and Ahn, Young-Ho and Byers, Lauren A and Zhang, Xuejun and Yi, Xiaohui and Dwyer, David and Lin, Wei and Diao, Lixia and Wang, Jing and Roybal, Jonathon D and Patel, Mayuri and Ungewiss, Christin and Peng, David and Antonia, Scott and Mediavilla-Varela, Melanie and Robertson, Gordon and Jones, Steve and Suraokar, Milind and Welsh, James W and Erez, Baruch and Wistuba, Ignacio I and Chen, Lieping and Peng, Di and Wang, Shanshan and Ullrich, Stephen E and Heymach, John V and Kurie, Jonathan M and Qin, F. Xiao-Feng
Nature communications, ISSN 2041-1723, 10/2014, Volume 5, Issue 1, pp. 5241 - 5241
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Cell Proliferation | Homeodomain Proteins - metabolism | Humans | Lung Neoplasms - pathology | Male | MicroRNAs - metabolism | Epithelial-Mesenchymal Transition - genetics | Immunity | CD8-Positive T-Lymphocytes | Neoplasm Metastasis | Kruppel-Like Transcription Factors - metabolism | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Gene Targeting | Carcinoma, Non-Small-Cell Lung - genetics | Mice, Inbred C57BL | Immune Tolerance | Databases as Topic | Carcinoma, Non-Small-Cell Lung - immunology | Transcription Factors - metabolism | B7-H1 Antigen - metabolism | Lung Neoplasms - immunology | Phenotype | Animals | Models, Biological | Cell Line, Tumor | MicroRNAs - genetics | Lymphocytes, Tumor-Infiltrating - immunology | Zinc Finger E-box-Binding Homeobox 1 | Index Medicus
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4. Full Text Multi-omics prediction of immune-related adverse events during checkpoint immunotherapy
by Jing, Ying and Liu, Jin and Ye, Youqiong and Pan, Lei and Deng, Hui and Wang, Yushu and Yang, Yang and Diao, Lixia and Lin, Steven H and Mills, Gordon B and Zhuang, Guanglei and Xue, Xinying and Han, Leng
Nature communications, ISSN 2041-1723, 12/2020, Volume 11, Issue 1, pp. 4946 - 4946
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Regression models | Bivariate analysis | PD-1 protein | Immunotherapy | PD-L1 protein | Antibodies | Biomarkers | Activation | Pharmacology | Cancer | Immune system | Index Medicus
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5. Full Text Targeting AXL and mTOR pathway overcomes primary and acquired resistance to WEE1 inhibition in small-cell lung cancer
by Sen, Triparna and Tong, Pan and Diao, Lixia and Li, Lerong and Fan, Youhong and Hoff, Jennifer and Heymach, John V and Wang, Jing and Byers, Lauren Averett
Clinical cancer research, ISSN 1078-0432, 10/2017, Volume 23, Issue 20, pp. 6239 - 6254
Life Sciences & Biomedicine | Oncology | Science & Technology | TOR Serine-Threonine Kinases - metabolism | Apoptosis - drug effects | Protein-Tyrosine Kinases - metabolism | Humans | Lung Neoplasms - metabolism | Apoptosis - genetics | Drug Resistance, Neoplasm | Lung Neoplasms - pathology | Extracellular Signal-Regulated MAP Kinases - metabolism | Cell Cycle Proteins - antagonists & inhibitors | Small Cell Lung Carcinoma - metabolism | Protein-Tyrosine Kinases - genetics | Ribosomal Protein S6 Kinases, 90-kDa - metabolism | Cell Cycle Proteins - genetics | DNA Damage - genetics | Female | Nuclear Proteins - genetics | Disease Models, Animal | Pyrazoles - pharmacology | DNA Damage - drug effects | Lung Neoplasms - genetics | Proto-Oncogene Proteins - metabolism | Gene Expression | Cell Cycle Proteins - metabolism | Nuclear Proteins - metabolism | Small Cell Lung Carcinoma - genetics | Pyrimidines - pharmacology | Receptor Protein-Tyrosine Kinases - metabolism | Xenograft Model Antitumor Assays | Small Cell Lung Carcinoma - pathology | Animals | Signal Transduction - drug effects | DNA Repair | Nuclear Proteins - antagonists & inhibitors | Cell Line, Tumor | Mice | Protein Kinase Inhibitors - pharmacology | Protein-Tyrosine Kinases - antagonists & inhibitors | TOR protein | Drugs | Medical research | Small cell lung carcinoma | Downstream effects | CHK1 protein | Lung cancer | DNA damage | Clinical trials | Extracellular signal-regulated kinase | Activation | Drug delivery | DNA repair | Axl protein | Recruitment | Proteins | Signaling | Protein arrays | Inhibitors | Experimental design | Inhibition | Repair | Deoxyribonucleic acid--DNA | Cancer | Index Medicus
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6. Full Text Assessing the clinical utility of cancer genomic and proteomic data across tumor types
by Yuan, Yuan and Van Allen, Eliezer M and Omberg, Larsson and Wagle, Nikhil and Amin-Mansour, Ali and Sokolov, Artem and Byers, Lauren A and Xu, Yanxun and Hess, Kenneth R and Diao, Lixia and Han, Leng and Huang, Xuelin and Lawrence, Michael S and Weinstein, John N and Stuart, Josh M and Mills, Gordon B and Garraway, Levi A and Margolin, Adam A and Getz, Gad and Liang, Han
Nature biotechnology, ISSN 1087-0156, 2014, Volume 32, Issue 7, pp. 644 - 652
Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Genetic Predisposition to Disease - genetics | Proteome - genetics | Prevalence | Risk Assessment | Humans | Databases, Genetic | Neoplasms - mortality | Neoplasms - classification | Neoplasms - genetics | Genetic Markers - genetics | Survival Analysis | Biomarkers, Tumor - genetics | DNA, Neoplasm - genetics | Genetic Predisposition to Disease - epidemiology | Clinical trials | Genetic aspects | Research | Methods | Proteomics | Cancer | Oncology | Genomics | Medical prognosis | Index Medicus
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7. Full Text An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance
by Byers, Lauren Averett and Diao, Lixia and Wang, Jing and Saintigny, Pierre and Girard, Luc and Peyton, Michael and Shen, Li and Fan, Youhong and Giri, Uma and Tumula, Praveen K and Nilsson, Monique B and Gudikote, Jayanthi and Tran, Hai and Cardnell, Robert J. G and Bearss, David J and Warner, Steven L and Foulks, Jason M and Kanner, Steven B and Gandhi, Varsha and Krett, Nancy and Rosen, Steven T and Kim, Edward S and Herbst, Roy S and Blumenschein, George R and Lee, J. Jack and Lippman, Scott M and Ang, K. Kian and Mills, Gordon B and Hong, Waun K and Weinstein, John N and Wistuba, Ignacio I and Coombes, Kevin R and Minna, John D and Heymach, John V
Clinical cancer research, ISSN 1078-0432, 01/2013, Volume 19, Issue 1, pp. 279 - 290
Life Sciences & Biomedicine | Oncology | Science & Technology | Biological and medical sciences | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Lung Neoplasms - drug therapy | Proto-Oncogene Proteins - antagonists & inhibitors | Recurrence | Reproducibility of Results | Carcinoma, Non-Small-Cell Lung - genetics | Humans | Lung Neoplasms - pathology | Proteome | Gene Expression Profiling | Epithelial-Mesenchymal Transition - genetics | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Drug Resistance, Neoplasm - genetics | Neoplasm Metastasis | Animals | Proteomics | Cell Line, Tumor | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Mice | Protein Kinase Inhibitors - pharmacology | Carcinoma, Non-Small-Cell Lung - drug therapy | Cluster Analysis | Index Medicus | lung cancer | EGFR inhibition | PI3K inhibition | Axl | EMT
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8. Full Text A pan-cancer proteomic perspective on the cancer genome atlas
by Akbani, Rehan and Ng, Patrick Kwok Shing and Werner, Henrica M. J and Shahmoradgoli, Maria and Zhang, Fan and Ju, Zhenlin and Liu, Wenbin and Yang, Ji-Yeon and Yoshihara, Kosuke and Li, Jun and Ling, Shiyun and Seviour, Elena G and Ram, Prahlad T and Minna, John D and Diao, Lixia and Tong, Pan and Heymach, John V and Hill, Steven M and Dondelinger, Frank and Städler, Nicolas and Byers, Lauren A and Meric-Bernstam, Funda and Weinstein, John N and Broom, Bradley M and Verhaak, Roeland G.W and Liang, Han and Mukherjee, Sach and Lu, Yiling and Mills, Gordon B
Nature communications, ISSN 2041-1723, 05/2014, Volume 5, Issue 1, pp. 3887 - 3887
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Index Medicus
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9. Full Text Collagen promotes anti-PD-1/PD-L1 resistance in cancer through LAIR1-dependent CD8+ T cell exhaustion
by Peng, David H and Rodriguez, Bertha Leticia and Diao, Lixia and Chen, Limo and Wang, Jing and Byers, Lauren A and Wei, Ying and Chapman, Harold A and Yamauchi, Mitsuo and Behrens, Carmen and Raso, Gabriela and Soto, Luisa Maren Solis and Cuentes, Edwin Roger Parra and Wistuba, Ignacio I and Kurie, Jonathan M and Gibbons, Don L
Nature communications, ISSN 2041-1723, 12/2020, Volume 11, Issue 1, pp. 4520 - 4520
Subpopulations | Profiling | SHP-1 protein | PD-1 protein | CD8 antigen | Melanoma | Collagens | Lymphocytes T | Ribonucleic acid--RNA | Drug resistance | Metastases | Immunosuppression | Lungs | Lymphocytes | Immunotherapy | Exhaustion | Collagen | PD-L1 protein | Extracellular matrix | CD18 antigen | Tumors | Cancer | Index Medicus
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10. Full Text A Multi-Omics Perspective of Quantitative Trait Loci in Precision Medicine
by Ye, Youqiong and Zhang, Zhao and Liu, Yaoming and Diao, Lixia and Han, Leng
Trends in genetics, ISSN 0168-9525, 05/2020, Volume 36, Issue 5, pp. 318 - 336
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Index Medicus
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