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indexing scheme associated with subclasses f21k, f21l, f21sand f21v, relating to theform or the kind of the light sources or of the colour of thelight emitted (10) 10
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1. Full Text TANRIC: An interactive open platform to explore the function of IncRNAs in cancer
by Li, Jun and Han, Leng and Roebuck, Paul and Diao, Lixia and Liu, Lingxiang and Yuan, Yuan and Weinstein, John N and Liang, Han
Cancer Research, ISSN 0008-5472, 09/2015, Volume 75, Issue 18, pp. 3728 - 3737
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2. Full Text Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression
by Chen, Limo and Gibbons, Don L and Goswami, Sangeeta and Cortez, Maria Angelica and Ahn, Young-Ho and Byers, Lauren A and Zhang, Xuejun and Yi, Xiaohui and Dwyer, David and Lin, Wei and Diao, Lixia and Wang, Jing and Roybal, Jonathon D and Patel, Mayuri and Ungewiss, Christin and Peng, David and Antonia, Scott and Mediavilla-Varela, Melanie and Robertson, Gordon and Jones, Steve and Suraokar, Milind and Welsh, James W and Erez, Baruch and Wistuba, Ignacio I and Chen, Lieping and Peng, Di and Wang, Shanshan and Ullrich, Stephen E and Heymach, John V and Kurie, Jonathan M and Qin, F. Xiao-Feng
Nature Communications, ISSN 2041-1723, 10/2014, Volume 5, Issue 1, pp. 5241 - 5241
Immunosuppression of tumour-infiltrating lymphocytes (TIL) is a common feature of advanced cancer, but its biological basis has remained obscure. We... 
EPITHELIAL-MESENCHYMAL TRANSITION | LUNG-CANCER | INTERFERON-GAMMA | SAFETY | MULTIDISCIPLINARY SCIENCES | ANTIBODY | GENETIC MOUSE MODEL | MIR-200 FAMILY | REPRESSORS ZEB1 | EMT | T-CELLS | Cell Proliferation | Homeodomain Proteins - metabolism | Humans | Lung Neoplasms - pathology | Male | MicroRNAs - metabolism | Epithelial-Mesenchymal Transition - genetics | Immunity | CD8-Positive T-Lymphocytes | Neoplasm Metastasis | Kruppel-Like Transcription Factors - metabolism | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Gene Targeting | Carcinoma, Non-Small-Cell Lung - genetics | Mice, Inbred C57BL | Immune Tolerance | Databases as Topic | Carcinoma, Non-Small-Cell Lung - immunology | Transcription Factors - metabolism | B7-H1 Antigen - metabolism | Lung Neoplasms - immunology | Phenotype | Animals | Models, Biological | Cell Line, Tumor | MicroRNAs - genetics | Lymphocytes, Tumor-Infiltrating - immunology | Zinc Finger E-box-Binding Homeobox 1 | Index Medicus
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3. Full Text A pan-cancer proteomic perspective on the cancer genome atlas
by Akbani, Rehan and Ng, Patrick Kwok Shing and Werner, Henrica M. J and Shahmoradgoli, Maria and Zhang, Fan and Ju, Zhenlin and Liu, Wenbin and Yang, Ji-Yeon and Yoshihara, Kosuke and Li, Jun and Ling, Shiyun and Seviour, Elena G and Ram, Prahlad T and Minna, John D and Diao, Lixia and Tong, Pan and Heymach, John V and Hill, Steven M and Dondelinger, Frank and Städler, Nicolas and Byers, Lauren A and Meric-Bernstam, Funda and Weinstein, John N and Broom, Bradley M and Verhaak, Roeland G.W and Liang, Han and Mukherjee, Sach and Lu, Yiling and Mills, Gordon B
Nature Communications, ISSN 2041-1723, 05/2014, Volume 5, Issue 1, pp. 3887 - 3887
Protein levels and function are poorly predicted by genomic and transcriptomic analysis of patient tumours. Therefore, direct study of the functional proteome... 
BREAST-CANCER | PATHWAY ACTIVATION | MESSENGER-RNA | MULTIDISCIPLINARY SCIENCES | PROTEIN EXPRESSION | COPY NUMBER | SQUAMOUS-CELL CARCINOMA | GENE AMPLIFICATION | E-CADHERIN | HER2 | MICROARRAY ANALYSIS | Index Medicus
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4. Full Text Assessing the clinical utility of cancer genomic and proteomic data across tumor types
by Yuan, Yuan and Van Allen, Eliezer M and Omberg, Larsson and Wagle, Nikhil and Amin-Mansour, Ali and Sokolov, Artem and Byers, Lauren A and Xu, Yanxun and Hess, Kenneth R and Diao, Lixia and Han, Leng and Huang, Xuelin and Lawrence, Michael S and Weinstein, John N and Stuart, Josh M and Mills, Gordon B and Garraway, Levi A and Margolin, Adam A and Getz, Gad and Liang, Han
Nature Biotechnology, ISSN 1087-0156, 2014, Volume 32, Issue 7, pp. 644 - 652
Molecular profiling of tumors promises to advance the clinical management of cancer, but the benefits of integrating molecular data with traditional clinical... 
CELL LUNG-CANCER | SURVIVAL | BIOMARKERS | SUPPRESSOR | EVEROLIMUS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | VALIDATION | RESISTANCE | MUTATIONS | EXPRESSION | BREAST | Clinical trials | Genetic aspects | Research | Methods | Proteomics | Cancer | Oncology | Genomics | Medical prognosis | Index Medicus
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5. Full Text Effect of KRAS Oncogene Substitutions on Protein Behavior: Implications for Signaling and Clinical Outcome
by Ihle, Nathan T and Byers, Lauren A and Kim, Edward S and Saintigny, Pierre and Lee, J. Jack and Blumenschein, George R and Tsao, Anne and Liu, Suyu and Larsen, Jill E and Wang, Jing and Diao, Lixia and Coombes, Kevin R and Chen, Lu and Zhang, Shuxing and Abdelmelek, Mena F and Tang, Ximing and Papadimitrakopoulou, Vassiliki and Minna, John D and Lippman, Scott M and Hong, Waun K and Herbst, Roy S and Wistuba, Ignacio I and Heymach, John V and Powis, Garth
Journal of the National Cancer Institute, ISSN 0027-8874, 2012, Volume 104, Issue 3, pp. 228 - 239
Background Mutations in the v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) play a critical role in cancer cell growth and resistance to therapy.... 
PATHWAYS | ALLELE | LUNG-CANCER | CELLS | MOLECULAR-DYNAMICS | GENE | ONCOLOGY | RAS MUTATIONS | PROLIFERATION | SPECTRUM | Lung Neoplasms - drug therapy | Cysteine | Immunoprecipitation | TOR Serine-Threonine Kinases - metabolism | Lung Neoplasms - mortality | Humans | Lung Neoplasms - metabolism | Gene Expression Regulation, Neoplastic | Immunoblotting | Gene Expression Profiling | Aspartic Acid | Glycine | Molecular Targeted Therapy | Microarray Analysis | Proto-Oncogene Proteins c-akt - metabolism | Genes, ras - genetics | Lung Neoplasms - genetics | Signal Transduction | Carcinoma, Non-Small-Cell Lung - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Kaplan-Meier Estimate | Treatment Outcome | Carcinoma, Non-Small-Cell Lung - mortality | Lentivirus | Randomized Controlled Trials as Topic | Disease-Free Survival | Valine | Cell Line, Tumor | Carcinoma, Non-Small-Cell Lung - drug therapy | Mutation | Genetic Vectors | Clinical Trials, Phase II as Topic | Animal experimentation | Proteins | Usage | Gene mutations | Colorectal cancer | Physiological aspects | Genetic aspects | Research | Amino acids | Cell growth | Clinical outcomes | Index Medicus
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6. Full Text TANRIC: An Interactive Open Platform to Explore the Function of lncRNAs in Cancer
by Li, J and Han, L and Roebuck, P and Diao, LX and Liu, LX and Yuan, Y and Weinstein, JN and Liang, H
CANCER RESEARCH, ISSN 0008-5472, 09/2015, Volume 75, Issue 18, pp. 3728 - 3737
Long noncoding RNAs (lncRNA) have emerged as essential players in cancer biology. Using recent large-scale RNA-seq datasets, especially those from The Cancer... 
LONG NONCODING RNA | DATABASE | ONCOLOGY | LANDSCAPE | TRANSCRIPTION | SEQ | RESOURCE | User-Computer Interface | Algorithms | Neoplasms - genetics | Humans | Cell Line, Tumor | Databases, Genetic | Gene Expression Profiling | RNA, Long Noncoding - genetics | Software | Internet | Index Medicus | lncRNA expression | cancer genomics | prognostic marker | bioinformatics resource | TCGA
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7. Full Text The Pan-Cancer analysis of pseudogene expression reveals biologically and clinically relevant tumour subtypes
by Han, Leng and Yuan, Yuan and Zheng, Siyuan and Yang, Yang and Li, Jun and Edgerton, Mary E and Diao, Lixia and Xu, Yanxun and Verhaak, Roeland G. W and Liang, Han
Nature Communications, ISSN 2041-1723, 07/2014, Volume 5, Issue 1, pp. 3963 - 3963
Although individual pseudogenes have been implicated in tumour biology, the biomedical significance and clinical relevance of pseudogene expression have not... 
GENE | TARGETS | MULTIDISCIPLINARY SCIENCES | Neoplasms - metabolism | Gene Expression | Pseudogenes | Neoplasms - genetics | Genes, Neoplasm | Humans | Biomarkers, Tumor - metabolism | Neoplasms - classification | Biomarkers, Tumor - genetics | Index Medicus
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8. Full Text Identification and characterization of protein phosphorylation in the soluble protein fraction of scallop (Chlamys farreri) byssus
by Zhang, Lixia and Zhang, Xiaokang and Wang, Yujie and Xu, Pingping and Diao, Zhenli and Liu, Weizhi and Xu, Wenhua
Molecular biology reports, ISSN 0301-4851, 07/2019, pp. 1 - 9
Protein phosphorylation is a widespread modification that and plays a significant role in marine bioadhesion. The phosphorylated proteins of the barnacle... 
Phosphorylation | Calcium | Polymerization | Mass spectroscopy | Liquid chromatography | Tissue inhibitor of metalloproteinase 2 | Secretions | Kinases | Feet | Marine environment | Proteins | Composite materials | Phosphoproteins | Scientific imaging | Mass spectrometry
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9. Full Text Characterization of HPV and host genome interactions in primary head and neck cancers
by Michael Parfenov and Chandra Sekhar Pedamallu and Nils Gehlenborg and Samuel S. Freeman and Ludmila Danilova and Christopher A. Bristow and Semin Lee and Angela G. Hadjipanayis and Elena V. Ivanova and Matthew D. Wilkerson and Alexei Protopopov and Lixing Yang and Sahil Seth and Xingzhi Song and Jiabin Tang and Xiaojia Ren and Jianhua Zhang and Angeliki Pantazi and Netty Santoso and Andrew W. Xu and Harshad Mahadeshwar and David A. Wheeler and Robert I. Haddad and Joonil Jung and Akinyemi I. Ojesina and Natalia Issaeva and Wendell G. Yarbrough and D. Neil Hayes and Jennifer R. Grandis and Adel K. El-Naggar and Matthew Meyerson and Peter J. Park and Lynda Chin and J. G. Seidman and Peter S. Hammerman and Raju Kucherlapati and Canc Genome Atlas Network and Cancer Genome Atlas Network and the Cancer Genome Atlas Network
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2014, Volume 111, Issue 43, pp. 15544 - 15549
Previous studies have established that a subset of head and neck tumors contains human papillomavirus (HPV) sequences and that HPV-driven head and neck cancers... 
Head | Squamous cell carcinoma | Head and neck neoplasms | Genes | DNA | Genomes | Neck | Methylation | Tumors | Cancer | Head and neck | Papilloma virus | Genome rearrangement | Integration sites | CERVICAL CARCINOGENESIS | TRANSFORMATION | HUMAN-PAPILLOMAVIRUS TYPE-16 | MULTIDISCIPLINARY SCIENCES | KERATINOCYTES | integration sites | papilloma virus | INTEGRATION | genome rearrangement | OROPHARYNGEAL CANCER | PROSTATE-CANCER | SQUAMOUS-CELL CARCINOMA | head and neck | cancer | TUMORIGENESIS | Virus Integration - genetics | Head and Neck Neoplasms - virology | Host-Pathogen Interactions - genetics | Base Sequence | Genes, Neoplasm | Humans | Gene Expression Regulation, Neoplastic | Molecular Sequence Data | Head and Neck Neoplasms - genetics | DNA Methylation - genetics | Papillomaviridae - physiology | Genome, Human - genetics | Oncology, Experimental | Host-parasite relationships | Head and neck cancer | Development and progression | Genetic aspects | Research | Gene expression | Virus research | Papillomavirus infections | DNA methylation | Human papillomavirus | Head & neck cancer | Ribonucleic acid--RNA | Index Medicus | Biological Sciences
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10. Full Text Targeting AXL and mTOR pathway overcomes primary and acquired resistance to WEE1 inhibition in small-cell lung cancer
by Sen, Triparna and Tong, Pan and Diao, Lixia and Li, Lerong and Fan, Youhong and Hoff, Jennifer and Heymach, John V and Wang, Jing and Byers, Lauren Averett
Clinical Cancer Research, ISSN 1078-0432, 10/2017, Volume 23, Issue 20, pp. 6239 - 6254
Purpose: Drugs targeting DNA repair and cell-cycle checkpoints have emerged as promising therapies for small-cell lung cancer (SCLC). Among these, the WEE1... 
AZD1775 | PHASE-II TRIAL | MULTICENTER | MONOTHERAPY | CISPLATIN | ONCOLOGY | CHECKPOINT | ANTITUMOR-ACTIVITY | COMBINATION | CHEMOTHERAPY | TEMOZOLOMIDE | TOR protein | Drugs | Medical research | Downstream effects | CHK1 protein | Lung cancer | DNA damage | Clinical trials | Extracellular signal-regulated kinase | Activation | Drug delivery | DNA repair | Axl protein | Recruitment | Proteins | Signaling | Protein arrays | Inhibitors | Experimental design | Cell lines | Inhibition | Repair | Deoxyribonucleic acid--DNA | Cancer | Index Medicus
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11. Full Text Characteristic male urine microbiomes associate with asymptomatic sexually transmitted infection
by Nelson, David E and van der Pol, Barbara and Dong, Qunfeng and Revanna, Kashi V and Fan, Baochang and Easwaran, Shraddha and Sodergren, Erica and Weinstock, George M and Diao, Lixia and Fortenberry, Dennis J
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 11, pp. e14116 - e14116
Background: The microbiome of the male urogenital tract is poorly described but it has been suggested that bacterial colonization of the male urethra might... 
WOMEN | CHLAMYDIA-TRACHOMATIS | GUT MICROBIOME | MULTIDISCIPLINARY SCIENCES | LIGASE CHAIN-REACTION | NONGONOCOCCAL URETHRITIS | MEN | COMMUNITIES | INFLAMMATORY BOWEL DISEASES | TESTING 1ST-VOID URINE | BACTERIAL VAGINOSIS | Sexually Transmitted Diseases - microbiology | Sexually Transmitted Diseases - urine | Humans | Middle Aged | Male | DNA, Bacterial - chemistry | Phylogeny | Bacteria - genetics | Sequence Analysis, DNA | Young Adult | Bacteria - isolation & purification | DNA, Bacterial - genetics | Bacteria - classification | RNA, Ribosomal, 16S - genetics | Adult | Metagenome | Urethra - microbiology | Urine - microbiology | Prevention | Medical research | Sexually transmitted diseases | Disease transmission | RNA | Medicine, Experimental | Bacteria | Health aspects | Urine | rRNA 16S | Genital tract | Disease | Cultivation | Health risks | Vagina | Gram-positive bacteria | Infections | Biology | Medicine | Mens health | Taxa | Urethra | Antibiotics | Womens health | Men | Phylogenetics | Skin | Colonization | Deoxyribonucleic acid--DNA | Circumcision | Index Medicus | Deoxyribonucleic acid | DNA
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12. Full Text The microbial communities in male first catch urine are highly similar to those in paired urethral swab specimens
by Dong, Qunfeng and Nelson, David E and Toh, Evelyn and Diao, Lixia and Gao, Xiang and Fortenberry, J. Dennis and van Der Pol, Barbara
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 5, pp. e19709 - e19709
Urine is the CDC-recommended specimen for STI testing. It was unknown if the bacterial communities (microbiomes) in urine reflected those in the distal male... 
VAGINALIS | INFECTION | ASSOCIATION | CHLAMYDIA | NONGONOCOCCAL URETHRITIS | BIOLOGY | Sexually Transmitted Diseases - microbiology | Sexually Transmitted Diseases - urine | Humans | Male | Sexually Transmitted Diseases - diagnosis | Young Adult | Metagenome - genetics | Sequence Analysis, RNA | Polymerase Chain Reaction | RNA, Ribosomal, 16S - genetics | Adult | Urethra - microbiology | Urine - microbiology | RNA | Sexually transmitted diseases | Urine | Health care | Pathogens | Microbial activity | Sexually transmitted diseases--STD | rRNA 16S | Communities | Population studies | Infections | Biology | Gonorrhea | Males | Data bases | Studies | Microorganisms | Chlamydia | Urethra | Human immunodeficiency virus--HIV | Bacteria | Life sciences | Bioinformatics | Deoxyribonucleic acid--DNA | Circumcision | Index Medicus | STD | Deoxyribonucleic acid | HIV | DNA | Human immunodeficiency virus
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13. Full Text Activation of the PI3K/mTOR pathway following PARP inhibition in small cell lung cancer
by Cardnell, Robert J and Feng, Ying and Mukherjee, Seema and Diao, Lixia and Tong, Pan and Allison Stewart, C and Masrorpour, Fatemeh and Fan, YouHong and Nilsson, Monique and Shen, Yuqiao and Heymach, John V and Wang, Jing and Byers, Lauren A
PLoS ONE, ISSN 1932-6203, 04/2016, Volume 11, Issue 4, pp. e0152584 - e0152584
Small cell lung cancer (SCLC) is an aggressive malignancy with limited treatment options. We previously found that PARP is overexpressed in SCLC and that... 
BREAST-CANCER | POLY(ADP-RIBOSE) POLYMERASE | IN-VITRO | MULTIDISCIPLINARY SCIENCES | RESISTANCE | THERAPEUTIC TARGETS | DNA-REPAIR | TUMORS | CARCINOMA | DRUG-DRUG INTERACTIONS | PI3K INHIBITOR | Lung Neoplasms - drug therapy | AMP-Activated Protein Kinases - metabolism | TOR Serine-Threonine Kinases - metabolism | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | Neoplasm Proteins - antagonists & inhibitors | Phosphatidylinositol 3-Kinases - metabolism | Neoplasm Proteins - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Small Cell Lung Carcinoma - drug therapy | Small Cell Lung Carcinoma - metabolism | TOR Serine-Threonine Kinases - antagonists & inhibitors | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Female | Indoles - pharmacology | Protein-Serine-Threonine Kinases - metabolism | Signal Transduction | AMP-Activated Protein Kinases - antagonists & inhibitors | Morpholines - pharmacology | Piperazines - pharmacology | Xenograft Model Antitumor Assays | Phthalazines - pharmacology | Poly(ADP-ribose) Polymerase Inhibitors - pharmacology | Poly(ADP-ribose) Polymerases - metabolism | Small Cell Lung Carcinoma - pathology | Animals | Mice, Nude | Aminopyridines - pharmacology | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Poly (ADP-Ribose) Polymerase-1 | Physiological aspects | Lung cancer, Small cell | Development and progression | Genetic aspects | Cellular signal transduction | Research | TOR protein | Drugs | Cell culture | Biotechnology | Animal models | Lung cancer | AKT protein | Oncology | Biology | Activation | Malignancy | Kinases | Cancer therapies | DNA repair | Ovarian cancer | Proteins | LKB1 protein | Signal transduction | Rodents | Bioindicators | Inhibition | Bioinformatics | Pharmaceutical sciences | Deoxyribonucleic acid--DNA | Medical research | Poly(ADP-ribose) polymerase | Breast cancer | Bioavailability | 1-Phosphatidylinositol 3-kinase | Studies | Signaling | Chemotherapy | Gene amplification | Protein arrays | Inhibitors | Biopsy | Cell lines | Biomarkers | In vivo methods and tests | ATP | Tumors | Cancer | Index Medicus | Deoxyribonucleic acid | DNA
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