CIRCULATION, ISSN 0009-7322, 04/2009, Volume 119, Issue 16, pp. F91 - F94
Journal Article
EUROPEAN HEART JOURNAL, ISSN 0195-668X, 12/2010, Volume 31, Issue 24, pp. 2969 - 2970
Journal Article
American Journal of Medicine, The, ISSN 0002-9343, 2007, Volume 120, Issue 3, pp. e27 - e27
Journal Article
American Heart Journal, ISSN 0002-8703, 2015, Volume 169, Issue 5, pp. 631 - 638.e7
Background Cardiovascular (CV) disease is the leading cause of morbidity and mortality in patients with type 2 diabetes mellitus (T2DM). Furthermore, patients...
Cardiovascular | EXENATIDE TWICE | CARDIAC & CARDIOVASCULAR SYSTEMS | GLUCOSE CONTROL | ONCE-DAILY LIXISENATIDE | REPERFUSION INJURY | HEART-FAILURE | DOUBLE-BLIND | RECEPTOR AGONIST LIXISENATIDE | RANDOMIZED CLINICAL-TRIALS | TYPE-2 DIABETES-MELLITUS | ELEVATION MYOCARDIAL-INFARCTION | Cardiovascular Diseases | Double-Blind Method | Humans | Middle Aged | Male | Peptides - pharmacology | Acute Coronary Syndrome - drug therapy | Glucagon-Like Peptide 1 - agonists | Protein Kinase Inhibitors - therapeutic use | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Placebos | Female | Aged | p38 Mitogen-Activated Protein Kinases - metabolism | Research Design | Peptides - therapeutic use | Type 2 diabetes | Glucagon | Coronary heart disease | Analysis | Cardiovascular disease | Heart attacks | Acute coronary syndromes | Mortality
Cardiovascular | EXENATIDE TWICE | CARDIAC & CARDIOVASCULAR SYSTEMS | GLUCOSE CONTROL | ONCE-DAILY LIXISENATIDE | REPERFUSION INJURY | HEART-FAILURE | DOUBLE-BLIND | RECEPTOR AGONIST LIXISENATIDE | RANDOMIZED CLINICAL-TRIALS | TYPE-2 DIABETES-MELLITUS | ELEVATION MYOCARDIAL-INFARCTION | Cardiovascular Diseases | Double-Blind Method | Humans | Middle Aged | Male | Peptides - pharmacology | Acute Coronary Syndrome - drug therapy | Glucagon-Like Peptide 1 - agonists | Protein Kinase Inhibitors - therapeutic use | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Placebos | Female | Aged | p38 Mitogen-Activated Protein Kinases - metabolism | Research Design | Peptides - therapeutic use | Type 2 diabetes | Glucagon | Coronary heart disease | Analysis | Cardiovascular disease | Heart attacks | Acute coronary syndromes | Mortality
Journal Article
American Heart Journal, ISSN 0002-8703, 2015, Volume 170, Issue 2, pp. 290 - 297.e1
Background Patients hospitalized for acute decompensated heart failure (ADHF) are at high risk for early mortality and rehospitalization. Risk stratification...
Cardiovascular | MORTALITY | TRIAL | SURVIVAL | IMPACT | ADMISSION | RISK STRATIFICATION | HYPONATREMIA | OPTIMIZE-HF | NATIONAL REGISTRY ADHERE | WORSENING RENAL-FUNCTION | CARDIAC & CARDIOVASCULAR SYSTEMS | Latin America - epidemiology | Risk Assessment - methods | United States - epidemiology | Acute Disease | Injections, Intravenous | Survival Rate - trends | Double-Blind Method | Outcome Assessment (Health Care) | Humans | Middle Aged | Ventricular Function, Left - drug effects | Heart Failure - physiopathology | Europe - epidemiology | Patient Readmission - trends | Male | Natriuretic Peptide, Brain - administration & dosage | Heart Failure - drug therapy | Natriuretic Agents - administration & dosage | Cause of Death - trends | Female | Ventricular Function, Left - physiology | Aged | Retrospective Studies | Heart Failure - mortality | Heart failure | Patient outcomes | Edema | Heart attacks | Mortality | Cardiovascular disease | Family medical history | Patients | Variables | Datasets | Sodium | Data collection | Chronic obstructive pulmonary disease | Clinical medicine | Age | Methods | Logistics
Cardiovascular | MORTALITY | TRIAL | SURVIVAL | IMPACT | ADMISSION | RISK STRATIFICATION | HYPONATREMIA | OPTIMIZE-HF | NATIONAL REGISTRY ADHERE | WORSENING RENAL-FUNCTION | CARDIAC & CARDIOVASCULAR SYSTEMS | Latin America - epidemiology | Risk Assessment - methods | United States - epidemiology | Acute Disease | Injections, Intravenous | Survival Rate - trends | Double-Blind Method | Outcome Assessment (Health Care) | Humans | Middle Aged | Ventricular Function, Left - drug effects | Heart Failure - physiopathology | Europe - epidemiology | Patient Readmission - trends | Male | Natriuretic Peptide, Brain - administration & dosage | Heart Failure - drug therapy | Natriuretic Agents - administration & dosage | Cause of Death - trends | Female | Ventricular Function, Left - physiology | Aged | Retrospective Studies | Heart Failure - mortality | Heart failure | Patient outcomes | Edema | Heart attacks | Mortality | Cardiovascular disease | Family medical history | Patients | Variables | Datasets | Sodium | Data collection | Chronic obstructive pulmonary disease | Clinical medicine | Age | Methods | Logistics
Journal Article
American Journal of Cardiology, The, ISSN 0002-9149, 06/2016, Volume 117, Issue 11, pp. 1771 - 1778
A growing number of countries and geographical regions are involved in major clinical trials. Acute Study of Clinical Effectiveness of Nesiritide in...
Cardiovascular | MANAGEMENT | CLOPIDOGREL | COUNTRIES | TICAGRELOR | GLOBALIZATION | ACUTE MYOCARDIAL-INFARCTION | INTERNATIONAL DIFFERENCES | OUTCOMES | READMISSION RATES | NESIRITIDE | CARDIAC & CARDIOVASCULAR SYSTEMS | Risk Assessment - methods | Acute Disease | Survival Rate - trends | Global Health | Humans | Middle Aged | Male | Heart Failure - therapy | Hospitalization - trends | Cause of Death - trends | Female | Aged | Heart Failure - epidemiology | Heart failure | Clinical trials | Mortality | Medicine, Experimental | Medical research | Studies | Anticoagulants | Heart attacks | Enrollments | Cardiovascular disease | Patients | Clinical outcomes | clopidogrel | readmission | acute myocardial-infarction | globalization | rates | ticagrelor | countries | Kardiologi | nesiritide | Cardiac and Cardiovascular Systems | Cardiovascular System & Cardiology | international differences | outcomes | management
Cardiovascular | MANAGEMENT | CLOPIDOGREL | COUNTRIES | TICAGRELOR | GLOBALIZATION | ACUTE MYOCARDIAL-INFARCTION | INTERNATIONAL DIFFERENCES | OUTCOMES | READMISSION RATES | NESIRITIDE | CARDIAC & CARDIOVASCULAR SYSTEMS | Risk Assessment - methods | Acute Disease | Survival Rate - trends | Global Health | Humans | Middle Aged | Male | Heart Failure - therapy | Hospitalization - trends | Cause of Death - trends | Female | Aged | Heart Failure - epidemiology | Heart failure | Clinical trials | Mortality | Medicine, Experimental | Medical research | Studies | Anticoagulants | Heart attacks | Enrollments | Cardiovascular disease | Patients | Clinical outcomes | clopidogrel | readmission | acute myocardial-infarction | globalization | rates | ticagrelor | countries | Kardiologi | nesiritide | Cardiac and Cardiovascular Systems | Cardiovascular System & Cardiology | international differences | outcomes | management
Journal Article
American Journal of Cardiology, The, ISSN 0002-9149, 2015, Volume 117, Issue 9, pp. 1482 - 1487
Abstract Clinical status in heart failure is conventionally assessed by the physician's evaluation, patients' own perception of their symptoms, quality of life...
Cardiovascular | Heart Failure - complications | Follow-Up Studies | Hematinics - therapeutic use | Humans | Middle Aged | Self Report | Heart Failure - physiopathology | Male | Treatment Outcome | Anemia - physiopathology | Anemia - complications | Exercise Test | Anemia - drug therapy | Maltose - analogs & derivatives | Exercise Tolerance - physiology | Ferric Compounds - therapeutic use | Quality of Life | Recovery of Function - physiology | Female | Maltose - therapeutic use | Aged | Heart Failure - psychology | Longitudinal Studies | Heart failure | Heart | Care and treatment | Iron compounds | Anemia | Analysis | Cardiac patients | Studies | Heart attacks | Cardiomyopathy | Questionnaires | Clinical trials | Population | Patients | Beta blockers
Cardiovascular | Heart Failure - complications | Follow-Up Studies | Hematinics - therapeutic use | Humans | Middle Aged | Self Report | Heart Failure - physiopathology | Male | Treatment Outcome | Anemia - physiopathology | Anemia - complications | Exercise Test | Anemia - drug therapy | Maltose - analogs & derivatives | Exercise Tolerance - physiology | Ferric Compounds - therapeutic use | Quality of Life | Recovery of Function - physiology | Female | Maltose - therapeutic use | Aged | Heart Failure - psychology | Longitudinal Studies | Heart failure | Heart | Care and treatment | Iron compounds | Anemia | Analysis | Cardiac patients | Studies | Heart attacks | Cardiomyopathy | Questionnaires | Clinical trials | Population | Patients | Beta blockers
Journal Article
American Journal of Cardiology, The, ISSN 0002-9149, 2007, Volume 99, Issue 8, pp. 1109 - 1114
Studies of patients with acute myocardial infarction (MI) suggest that anterior transmural infarcts are associated with greater left ventricular (LV)...
Cardiovascular | MORTALITY | VISUALIZATION | HEART | TRIAL | CARDIAC & CARDIOVASCULAR SYSTEMS | MORBIDITY | ERA | CARDIOVASCULAR MAGNETIC-RESONANCE | EXPANSION | ENHANCEMENT | Follow-Up Studies | Image Enhancement | Humans | Middle Aged | Male | Cicatrix - physiopathology | Myocardial Infarction - pathology | Myocardial Ischemia - physiopathology | Female | Myocardial Infarction - physiopathology | Registries | Heart Ventricles - pathology | Stroke Volume - physiology | Cardiac Volume - physiology | Myocardium - pathology | Ventricular Remodeling - physiology | Myocardial Ischemia - pathology | Magnetic Resonance Imaging | Contrast Media | Aged | Cicatrix - pathology | Wound Healing - physiology | Longitudinal Studies | Cohort Studies | Gadolinium DTPA | Cardiology | Heart attack
Cardiovascular | MORTALITY | VISUALIZATION | HEART | TRIAL | CARDIAC & CARDIOVASCULAR SYSTEMS | MORBIDITY | ERA | CARDIOVASCULAR MAGNETIC-RESONANCE | EXPANSION | ENHANCEMENT | Follow-Up Studies | Image Enhancement | Humans | Middle Aged | Male | Cicatrix - physiopathology | Myocardial Infarction - pathology | Myocardial Ischemia - physiopathology | Female | Myocardial Infarction - physiopathology | Registries | Heart Ventricles - pathology | Stroke Volume - physiology | Cardiac Volume - physiology | Myocardium - pathology | Ventricular Remodeling - physiology | Myocardial Ischemia - pathology | Magnetic Resonance Imaging | Contrast Media | Aged | Cicatrix - pathology | Wound Healing - physiology | Longitudinal Studies | Cohort Studies | Gadolinium DTPA | Cardiology | Heart attack
Journal Article
9.
Full Text
Acute Treatment With Omecamtiv Mecarbil to Increase Contractility in Acute Heart Failure
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2016, Volume 67, Issue 12, pp. 1444 - 1455
Abstract Background Omecamtiv mecarbil (OM) is a selective cardiac myosin activator that increases myocardial function in healthy volunteers and in patients...
Cardiovascular | Internal Medicine | cardiac myosin activator | dyspnea | arrhythmia | inotrope | Heart failure | Medical colleges | Muscle proteins | Cardiac patients | Hospitals, Military | Myosin
Cardiovascular | Internal Medicine | cardiac myosin activator | dyspnea | arrhythmia | inotrope | Heart failure | Medical colleges | Muscle proteins | Cardiac patients | Hospitals, Military | Myosin
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2009, Volume 54, Issue 16, pp. 1522 - 1523
Journal Article
American Journal of Cardiology, The, ISSN 0002-9149, 2009, Volume 104, Issue 9, pp. 1179 - 1183
Increased circulating chemokines have been reported during acute myocardial infarction and might give prognostic information about future ischemic events....
Cardiovascular | CYTOKINES | CARDIAC & CARDIOVASCULAR SYSTEMS | ATHEROSCLEROSIS | MARKERS | ISCHEMIA | RECEPTOR | EXPRESSION | INTERLEUKIN-8 | CXCL16 | Severity of Illness Index | Myocardial Infarction - blood | Chemokines - blood | Prospective Studies | Humans | Middle Aged | Cardiac Output | Male | Magnetic Resonance Imaging, Cine | Angioplasty, Balloon, Coronary | Myocardial Infarction - therapy | Ventricular Remodeling | Troponin T - blood | Myocardial Infarction - pathology | Peptide Fragments - blood | Female | Natriuretic Peptide, Brain - blood
Cardiovascular | CYTOKINES | CARDIAC & CARDIOVASCULAR SYSTEMS | ATHEROSCLEROSIS | MARKERS | ISCHEMIA | RECEPTOR | EXPRESSION | INTERLEUKIN-8 | CXCL16 | Severity of Illness Index | Myocardial Infarction - blood | Chemokines - blood | Prospective Studies | Humans | Middle Aged | Cardiac Output | Male | Magnetic Resonance Imaging, Cine | Angioplasty, Balloon, Coronary | Myocardial Infarction - therapy | Ventricular Remodeling | Troponin T - blood | Myocardial Infarction - pathology | Peptide Fragments - blood | Female | Natriuretic Peptide, Brain - blood
Journal Article
Journal of Cardiac Failure, ISSN 1071-9164, 2007, Volume 13, Issue 10, pp. 843 - 849
Abstract Background Altered activity of the matrix metalloproteinases (MMP-2 and -9), has been implicated in the left ventricular (LV) remodeling process...
Cardiovascular | natriuretic peptides | Long-term remodeling | scarring | gelatinases | cardiac magnetic resonance | myocardial infarction | VISUALIZATION | CARDIAC & CARDIOVASCULAR SYSTEMS | BRAIN NATRIURETIC PEPTIDE | HEART-FAILURE | ACUTE CORONARY SYNDROMES | DILATED CARDIOMYOPATHY | long-term remodeling | MATRIX-METALLOPROTEINASE-9 | TISSUE INHIBITOR | DYSFUNCTION | MATRIX-METALLOPROTEINASE INHIBITION | UP-REGULATION | Myocardial Infarction - blood | Prognosis | Follow-Up Studies | Angiotensin II Type 1 Receptor Blockers - therapeutic use | Humans | Magnetic Resonance Imaging - methods | Male | Captopril - therapeutic use | Angiotensin-Converting Enzyme Inhibitors - therapeutic use | Time Factors | Peptide Fragments - blood | Female | Myocardial Infarction - physiopathology | Ventricular Function, Left - physiology | Heart Ventricles - pathology | Natriuretic Peptide, Brain - blood | Matrix Metalloproteinase 9 - blood | Severity of Illness Index | Enzyme-Linked Immunosorbent Assay | Biomarkers - blood | Ventricular Remodeling - physiology | Stroke Volume | Matrix Metalloproteinase 2 - blood | Myocardial Infarction - drug therapy | Heart Ventricles - physiopathology | Losartan - therapeutic use | Aged | Magnetic resonance imaging | Heart attack
Cardiovascular | natriuretic peptides | Long-term remodeling | scarring | gelatinases | cardiac magnetic resonance | myocardial infarction | VISUALIZATION | CARDIAC & CARDIOVASCULAR SYSTEMS | BRAIN NATRIURETIC PEPTIDE | HEART-FAILURE | ACUTE CORONARY SYNDROMES | DILATED CARDIOMYOPATHY | long-term remodeling | MATRIX-METALLOPROTEINASE-9 | TISSUE INHIBITOR | DYSFUNCTION | MATRIX-METALLOPROTEINASE INHIBITION | UP-REGULATION | Myocardial Infarction - blood | Prognosis | Follow-Up Studies | Angiotensin II Type 1 Receptor Blockers - therapeutic use | Humans | Magnetic Resonance Imaging - methods | Male | Captopril - therapeutic use | Angiotensin-Converting Enzyme Inhibitors - therapeutic use | Time Factors | Peptide Fragments - blood | Female | Myocardial Infarction - physiopathology | Ventricular Function, Left - physiology | Heart Ventricles - pathology | Natriuretic Peptide, Brain - blood | Matrix Metalloproteinase 9 - blood | Severity of Illness Index | Enzyme-Linked Immunosorbent Assay | Biomarkers - blood | Ventricular Remodeling - physiology | Stroke Volume | Matrix Metalloproteinase 2 - blood | Myocardial Infarction - drug therapy | Heart Ventricles - physiopathology | Losartan - therapeutic use | Aged | Magnetic resonance imaging | Heart attack
Journal Article
American Heart Journal, ISSN 0002-8703, 2009, Volume 157, Issue 1, pp. 91 - 96
Background In patients with chronic heart failure, erythropoietin (Epo) levels are increased and related to a poor prognosis. Furthermore, Epo levels in these...
Cardiovascular | HEMOGLOBIN | MORTALITY | TRIAL | CIRCULATING ERYTHROPOIETIN | PLASMA ERYTHROPOIETIN | ANGIOTENSIN-II | ANEMIA | ANALOG DARBEPOETIN-ALPHA | UMCG Approved | CHRONIC-KIDNEY-DISEASE | SERUM ERYTHROPOIETIN | CARDIAC & CARDIOVASCULAR SYSTEMS | Myocardial Infarction - blood | Prognosis | Angiotensin II Type 1 Receptor Blockers - therapeutic use | Humans | Male | Heart Failure - blood | Heart Failure - drug therapy | Erythropoietin - blood | Captopril - therapeutic use | Myocardial Infarction - complications | Angiotensin-Converting Enzyme Inhibitors - therapeutic use | Losartan - therapeutic use | Female | Aged | Retrospective Studies | Heart Failure - etiology | Heart failure | Erythropoietin | Captopril | Hemoglobin | Universities and colleges | Growth factors | Heart attack | Heart attacks | Mortality | Medical prognosis | Ligands | Gender | Regression analysis | Kidney diseases | Age
Cardiovascular | HEMOGLOBIN | MORTALITY | TRIAL | CIRCULATING ERYTHROPOIETIN | PLASMA ERYTHROPOIETIN | ANGIOTENSIN-II | ANEMIA | ANALOG DARBEPOETIN-ALPHA | UMCG Approved | CHRONIC-KIDNEY-DISEASE | SERUM ERYTHROPOIETIN | CARDIAC & CARDIOVASCULAR SYSTEMS | Myocardial Infarction - blood | Prognosis | Angiotensin II Type 1 Receptor Blockers - therapeutic use | Humans | Male | Heart Failure - blood | Heart Failure - drug therapy | Erythropoietin - blood | Captopril - therapeutic use | Myocardial Infarction - complications | Angiotensin-Converting Enzyme Inhibitors - therapeutic use | Losartan - therapeutic use | Female | Aged | Retrospective Studies | Heart Failure - etiology | Heart failure | Erythropoietin | Captopril | Hemoglobin | Universities and colleges | Growth factors | Heart attack | Heart attacks | Mortality | Medical prognosis | Ligands | Gender | Regression analysis | Kidney diseases | Age
Journal Article
American Journal of Cardiology, The, ISSN 0002-9149, 2007, Volume 99, Issue 5, pp. 647 - 650
The presence or onset of bundle branch block (BBB) is associated with increased mortality in patients after acute myocardial infarction (AMI). The risk...
Cardiovascular | MORTALITY | SURVIVAL | LOSARTAN | CARDIAC & CARDIOVASCULAR SYSTEMS | ANGIOPLASTY | RESOLUTION | CLINICAL CHARACTERISTICS | OPTIMAAL TRIAL | CONGESTIVE-HEART-FAILURE | QRS DURATION | CAPTOPRIL | Predictive Value of Tests | Myocardial Infarction - mortality | Bundle-Branch Block - complications | Follow-Up Studies | Humans | Middle Aged | Bundle-Branch Block - physiopathology | Male | Survival Rate | Death, Sudden, Cardiac - etiology | Myocardial Infarction - complications | Aged, 80 and over | Electrocardiography | Female | Myocardial Infarction - physiopathology | Aged | Medicine, Experimental | Medical research | Heart diseases | Cardiac patients
Cardiovascular | MORTALITY | SURVIVAL | LOSARTAN | CARDIAC & CARDIOVASCULAR SYSTEMS | ANGIOPLASTY | RESOLUTION | CLINICAL CHARACTERISTICS | OPTIMAAL TRIAL | CONGESTIVE-HEART-FAILURE | QRS DURATION | CAPTOPRIL | Predictive Value of Tests | Myocardial Infarction - mortality | Bundle-Branch Block - complications | Follow-Up Studies | Humans | Middle Aged | Bundle-Branch Block - physiopathology | Male | Survival Rate | Death, Sudden, Cardiac - etiology | Myocardial Infarction - complications | Aged, 80 and over | Electrocardiography | Female | Myocardial Infarction - physiopathology | Aged | Medicine, Experimental | Medical research | Heart diseases | Cardiac patients
Journal Article
American Heart Journal, ISSN 0002-8703, 09/2019, Volume 215, pp. 83 - 90
Reduced left ventricular ejection fraction (LVEF) after acute myocardial infarction (MI) increases risk of cardiovascular (CV) hospitalizations, but evidence...
TRIAL | CARVEDILOL | CARDIAC & CARDIOVASCULAR SYSTEMS | RATIONALE | PREDICTORS | STABLE SURVIVORS | EPLERENONE | VALSARTAN | Heart failure | Heart | Analysis | Heart attack | Hypothesis testing | Hypertension | Myocardial infarction | Heart attacks | Risk groups | Health risks | Clinical trials | Risk | Family medical history | Data bases | Studies | Demographics | Medical prognosis | Failure analysis | Software | Chronic obstructive pulmonary disease | Diabetes | Ventricle | Cardiovascular diseases | Heart diseases | Ejection
TRIAL | CARVEDILOL | CARDIAC & CARDIOVASCULAR SYSTEMS | RATIONALE | PREDICTORS | STABLE SURVIVORS | EPLERENONE | VALSARTAN | Heart failure | Heart | Analysis | Heart attack | Hypothesis testing | Hypertension | Myocardial infarction | Heart attacks | Risk groups | Health risks | Clinical trials | Risk | Family medical history | Data bases | Studies | Demographics | Medical prognosis | Failure analysis | Software | Chronic obstructive pulmonary disease | Diabetes | Ventricle | Cardiovascular diseases | Heart diseases | Ejection
Journal Article