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NATURE COMMUNICATIONS, ISSN 2041-1723, 10/2019, Volume 10, Issue 1, pp. 1 - 13
Cellular homeostasis relies on having dedicated and coordinated responses to a variety of stresses. The accumulation of unfolded proteins in the endoplasmic... 
UNFOLDED PROTEIN RESPONSE | MITOFUSIN 2 | PATHWAY | MULTIDISCIPLINARY SCIENCES | MEMBRANES | ENDOPLASMIC-RETICULUM STRESS | IDENTIFICATION | DISCOVERY | Proteins | Mitochondria | Cell survival | Cell death | Protein folding | Homeostasis | Amino acids | Cell interactions | Endoplasmic reticulum | Cellular stress response
Journal Article
PLoS Pathogens, ISSN 1553-7366, 05/2018, Volume 14, Issue 5, p. e1007071
HIV-1 Tat is a key regulator of viral transcription, however little is known about the mechanisms that control its turnover in T cells. Here we use a novel... 
RNA-POLYMERASE-II | COMPLEX | TRANSCRIPTION | MICROBIOLOGY | SELECTIVE AUTOPHAGY | HISTONE METHYLATION DYNAMICS | VIROLOGY | PROTEIN-DEGRADATION | TRANSACTIVATION | ELONGATION | LATENCY | INFECTION | PARASITOLOGY | Immune Sera - immunology | Gene Expression | Immunoprecipitation | tat Gene Products, Human Immunodeficiency Virus - genetics | Humans | Transcriptional Activation - drug effects | Aminopyridines - antagonists & inhibitors | Deubiquitinating Enzymes - physiology | Autophagy | Hydrazones - pharmacology | Hydrazones - antagonists & inhibitors | Glycine Hydroxymethyltransferase - physiology | Ubiquitination | RNA, Viral - chemistry | Membrane Proteins - physiology | Aminopyridines - pharmacology | HeLa Cells | RNA, Viral - isolation & purification | tat Gene Products, Human Immunodeficiency Virus - metabolism | Ubiquitin | Physiological aspects | T cells | HIV (Viruses) | Analysis | Molecular targeted therapy | Care and treatment | Viral proteins | Innovations | Development and progression | Genetic aspects | Genetic transcription | HIV infection | Health aspects | Target recognition | Transcription | Destruction | Laboratories | Serine | Viruses | Lymphocytes T | Biosynthesis | Glycine | Kinases | Proteins | Spectrometry | Lymphocytes | Human immunodeficiency virus--HIV | Enzymes | Metabolism | Carbon | Molecular chains | Medicine | Tat protein | Infectious diseases | Proteomics | Cell lines | Point mutation | Scientific imaging | Mass spectrometry | Phagocytosis | HIV | Human immunodeficiency virus
Journal Article
Nature communications, ISSN 2041-1723, 03/2018, Volume 9, Issue 1, pp. 1113 - 1
In the original version of this Article, extraneous text not belonging to the article was accidentally appended to end of the first paragraph of the... 
Amino acids | Vegetables | Error correction | tRNA | Mimicry
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 04/2019, Volume 116, Issue 15, pp. 7363 - 7370
Coordination of growth and genomic stability is critical for normal cell physiology. Although the E3 ubiquitin ligase BRCA1 is a key player in maintenance of... 
LIGASE ACTIVITY | PHOSPHORYLATION | Hippo | MULTIDISCIPLINARY SCIENCES | PROLIFERATION | BRCA1 | BREAST | INHIBITION | ubiquitination | PATHWAY | TUMOR-SUPPRESSOR | cancer | NF2 | HOMOLOGOUS RECOMBINATION | TUMORIGENESIS | Neurofibromin 2 - genetics | Cell Proliferation | Humans | Mutation, Missense | Phosphoproteins - metabolism | Breast Neoplasms - metabolism | Ubiquitination | BRCA1 Protein - metabolism | Tumor Suppressor Proteins - genetics | HEK293 Cells | Female | Neurofibromin 2 - metabolism | Protein-Serine-Threonine Kinases - metabolism | Tumor Suppressor Proteins - metabolism | Signal Transduction | Protein-Serine-Threonine Kinases - genetics | Ubiquitin-Protein Ligases - metabolism | Phosphoproteins - genetics | BRCA1 Protein - genetics | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | Adaptor Proteins, Signal Transducing - metabolism | Ubiquitin-Protein Ligases - genetics | Amino Acid Substitution | Tumor suppressor genes | Breast cancer | Genetic aspects | Ubiquitin-proteasome system | Health aspects | Cell proliferation | Ubiquitin | Alanine | Phosphorylation | Stability | Transcription | BRCA1 protein | Epithelial cells | Neurofibromin 2 | Kinases | Proteins | Yes-associated protein | Signal transduction | Signaling | Epidermal growth factor | Yap1 protein | Tumorigenesis | Mammary gland | Ubiquitin-protein ligase | Biological Sciences | PNAS Plus
Journal Article
Analytical Chemistry, ISSN 0003-2700, 04/2016, Volume 88, Issue 7, p. 3967
  Computational, genomic, and proteomic approaches have been used to discover nonannotated protein-coding small open reading frames (smORFs). Some novel smORFs... 
Polypeptides | Genomics | Genes | Proteomics | Organisms | Cells
Journal Article
Experimental Parasitology, ISSN 0014-4894, 06/2019, Volume 201, pp. 11 - 20
The characteristics of parasitic infections are often tied to host behavior. Although most studies have investigated definitive hosts, intermediate hosts can... 
Fasciola hepatica | Secretome | Intermediate host | Parasite-host interaction | PROTEINASE-INHIBITORS | CATHEPSIN B2 | SERINE-PROTEASES | SCHISTOSOMA-MANSONI | INTERMEDIATE HOSTS | LIVER FLUKE | CYSTEINE PROTEASE INHIBITORS | INFECTION | HELMINTH PATHOGEN | EXPRESSION | PARASITOLOGY
Journal Article
Analytical Chemistry, ISSN 0003-2700, 09/2011, Volume 83, Issue 17, p. 6818
Identification of phosphorylation sites is of interest due to their importance in protein regulation; however, the identification of the exact sites of this... 
Proteins | Phosphorylation | Peptides | Comparative analysis | Mass spectrometry
Journal Article
G3 (Bethesda, Md.), 07/2019, Volume 9, Issue 7, p. 2235
The human pathogenic yeast silences transposable elements using endo-siRNAs and an Argonaute, Ago1. Endo-siRNAs production requires the RNA-dependent RNA... 
Journal Article
Analytical and Bioanalytical Chemistry, ISSN 1618-2642, 06/2012, Volume 403, Issue 8, p. 2269
Described herein is a method which combines bond selective fragmentation by photodissociation with online liquid chromatographic separation and mass... 
Proteins | Metabolites | Physiological aspects | Biological markers | Mass spectrometry | Methods
Journal Article
Ticks and Tick-borne Diseases, ISSN 1877-959X, 06/2019, Volume 10, Issue 4, pp. 787 - 797
Lipids play key roles in arthropod metabolism. In ticks, these biomolecules are transported from fat body to other organs, such as ovary and Gené’s organ.... 
Lipid gland | Proteome | Tick | Gené’s organ | Transcriptome | Egg wax
Journal Article
TICKS AND TICK-BORNE DISEASES, ISSN 1877-959X, 06/2019, Volume 10, Issue 4, pp. 787 - 797
Journal Article
Nature, ISSN 0028-0836, 02/2013, Volume 494, Issue 7438, pp. 502 - 505
Mammalian telomeres repress DNA-damage activation at natural chromosome ends by recruiting specific inhibitors of the DNA-damage machinery that form a... 
UBIQUITINATION | RECOMBINATION | MAINTENANCE | COMPLEX | REPAIR | MAMMALIAN TELOMERES | MULTIDISCIPLINARY SCIENCES | DNA-DAMAGE | CELL-CYCLE | PROTEINS | TRF2 | Tumor Suppressor Proteins - antagonists & inhibitors | Chromosomes, Mammalian - genetics | Protein Multimerization | Ubiquitin-Protein Ligases - antagonists & inhibitors | Telomeric Repeat Binding Protein 2 - chemistry | Cell Cycle Proteins - antagonists & inhibitors | DNA-Binding Proteins - metabolism | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Telomere - metabolism | Protein-Serine-Threonine Kinases - metabolism | Telomere - genetics | Protein Structure, Tertiary | Endopeptidases - metabolism | Tumor Suppressor Proteins - metabolism | DNA-Binding Proteins - antagonists & inhibitors | Chromosomal Proteins, Non-Histone - metabolism | Signal Transduction | Cell Cycle Proteins - metabolism | Ubiquitin-Protein Ligases - metabolism | Ataxia Telangiectasia Mutated Proteins | Endopeptidases - deficiency | Protein Transport | Animals | DNA Repair | Telomeric Repeat Binding Protein 2 - metabolism | Mice | DNA Damage | Enzyme Activation | Tumor Suppressor p53-Binding Protein 1 | Chromosomes, Mammalian - metabolism | Telomeres | Research | Binding proteins | Observations | Properties | DNA damage | Proteins | Enzymes | DNA methylation | Amino acids | Agreements | Telomerase | Chromosomes | RNF168 | Brca1 | genomic stability | telomere | ATM | NHEJ
Journal Article
Analytical Chemistry, ISSN 0003-2700, 09/2011, Volume 83, Issue 17, p. 6455
Disulfide bonds stabilize the tertiary and quaternary structure of proteins. Identifying the correct disulfide bond pairs can be extremely useful to understand... 
Proteins | Analytical chemistry | Ultraviolet radiation | Molecular structure | Chemical bonds | Mass spectrometry
Journal Article
Data in Brief, ISSN 2352-3409, 08/2019, Volume 25, p. 104272
Here we present the proteomic profile datasets of two NEJ isolates derived from different snail hosts: and . The data used in the analysis are related to the... 
Fasciola hepatica | Intermediate host | Secretome | Parasite-host interaction
Journal Article
Analytical Chemistry, ISSN 0003-2700, 05/2010, Volume 82, Issue 10, p. 4006
  Described herein are several unique analytical applications utilizing mass spectrometry and the selective modification of the free thiol form of cysteine in... 
Analytical chemistry | Proteins | Peptides | Mass spectrometry | Chemical compounds
Journal Article