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Journal Article
by Rosenthal, Rachel and Cadieux, Elizabeth Larose and Salgado, Roberto and Bakir, Maise Al and Moore, David A and Hiley, Crispin T and Lund, Tom and Tanić, Miljana and Reading, James L and Joshi, Kroopa and Henry, Jake Y and Ghorani, Ehsan and Wilson, Gareth A and Birkbak, Nicolai J and Jamal-Hanjani, Mariam and Veeriah, Selvaraju and Szallasi, Zoltan and Loi, Sherene and Hellmann, Matthew D and Feber, Andrew and Chain, Benny and Herrero, Javier and Quezada, Sergio A and Demeulemeester, Jonas and Van Loo, Peter and Beck, Stephan and McGranahan, Nicholas and Swanton, Charles and Swanton, Charles and Jamal-Hanjani, Mariam and Veeriah, Selvaraju and Czyzewska-Khan, Justyna and Johnson, Diana and Laycock, Joanne and Rosenthal, Rachel and Gorman, Pat and Hynds, Robert E and Wilson, Gareth and Birkbak, Nicolai J and Watkins, Thomas B. K and McGranahan, Nicholas and Escudero, Mickael and Stewart, Aengus and Van Loo, Peter and Rowan, Andrew and Hiley, Crispin T and Abbosh, Christopher and Goldman, Jacki and Stone, Richard Kevin and Denner, Tamara and Ward, Sophia and Nye, Emma and Joshi, Kroopa and Ben Aissa, Assma and Wong, Yien Ning Sophia and Georgiou, Andy and Quezada, Sergio and Hartley, John A and Lowe, Helen L and Herrero, Javier and Lawrence, David and Hayward, Martin and Panagiotopoulos, Nikolaos and Falzon, Mary and Borg, Elaine and Marafioti, Teresa and Janes, Sam M and Forster, Martin and Ahmad, Tanya and Lee, Siow Ming and Papadatos-Pastos, Dionysis and Carnell, Dawn and Mendes, Ruheena and George, Jeremy and Ahmed, Asia and Taylor, Magali and Choudhary, Junaid and Summers, Yvonne and Califano, Raffaele and Taylor, Paul and Shah, Rajesh and Krysiak, Piotr and Rammohan, Kendadai and Fontaine, Eustace and Booton, Richard and Evison, Matthew and Crosbie, Phil and Moss, Stuart and Joseph, Leena and Bishop, Paul and Quinn, Anne Marie and Doran, Helen and Leek, Angela and Harrison, Phil and Moore, Katrina and Waddington, Rachael and Novasio, Juliette and Blackhall, Fiona and Rogan, Jane and Smith, Elaine and ... and TRACERx Consortium and TRACERx consortium and The TRACERx consortium
Nature, ISSN 0028-0836, 03/2019, Volume 567, Issue 7749, pp. 479 - 485
The interplay between an evolving cancer and a dynamic immune microenvironment remains unclear. Here we analyse 258 regions from 88 early-stage, untreated... 
TUMOR-INFILTRATING LYMPHOCYTES | THERAPY | CELL | MULTIDISCIPLINARY SCIENCES | Adenocarcinoma - pathology | Prognosis | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - pathology | Humans | Lung Neoplasms - pathology | Male | Female | Adenocarcinoma - genetics | Gene Expression Regulation, Neoplastic - genetics | Tumor Escape - immunology | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Antigens, Neoplasm - genetics | Antigens, Neoplasm - immunology | Carcinoma, Non-Small-Cell Lung - genetics | Adenocarcinoma - immunology | Antigen Presentation - immunology | Carcinoma, Squamous Cell - immunology | Carcinoma, Non-Small-Cell Lung - immunology | Tumor Microenvironment - immunology | Disease-Free Survival | Lung Neoplasms - immunology | Evolution, Molecular | Lymphocytes, Tumor-Infiltrating - immunology | Causes of | Development and progression | Genetic aspects | Cellular immunity | Lung cancer | Working groups | Brain cancer | Editing | Genomes | Metastases | Gene sequencing | Histopathology | Lymphocytes | Evolution | Bioinformatics | Immune system | Antigens | T cell receptors | Ribonucleic acid--RNA | Estimates | Heterozygosity | White blood cells | Pathology | Depletion | Loss of heterozygosity | Epigenetics | Biomarkers | Ligands | Infiltration | Microenvironments | Mutation | Tumors | Cancer
Journal Article
Clinical Biochemistry, ISSN 0009-9120, 10/2015, Volume 48, Issue 15, pp. 1016 - 1016
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2016, Volume 113, Issue 36, pp. 10145 - 10150
Journal Article
Clinical Biochemistry, ISSN 0009-9120, 04/2015, Volume 48, Issue 6, pp. 443 - 447
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 09/2016, Volume 113, Issue 36, pp. 10145 - 10150
Journal Article
Proceedings of the National Academy of Sciences of the United States, ISSN 0027-8424, 09/2016, Volume 113, Issue 36, p. 10145
T helper 17 ([T.sub.H]17) cells represent a discrete TH cell subset instrumental in the immune response to extracellular bacteria and fungi. However,... 
Physiological aspects | Immune response | T cells | Observations | Protein kinases
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 09/2016, Volume 113, Issue 36, p. 10145
  T helper 17 (T^sub H^17) cells represent a discrete T^sub H^ cell subset instrumental in the immune response to extracellular bacteria and fungi. However,... 
Fungi | Encephalitis | Lymphocytes | Bacteria | Kinases | Autoimmune diseases
Journal Article
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 09/2016, Volume 113, Issue 36, pp. 10145 - 10145
T helper 17 (T sub( H)17) cells represent a discrete T sub( H) cell subset instrumental in the immune response to extracellular bacteria and fungi. However, T... 
Journal Article
Cell metabolism, ISSN 1550-4131, 9/2017, Volume 26, Issue 3, pp. 475 - 492.e7
Obesity and type-2 diabetes are associated with tissue-inflammation and metabolic defects in fat depots. Foxp3 + regulatory T(Treg) cells mediate T-cell... 
Journal Article
Journal of Immunology, ISSN 0022-1767, 07/2015, Volume 195, Issue 2, pp. 621 - 631
Journal Article
Science translational medicine, ISSN 1946-6234, 5/2016, Volume 8, Issue 337, pp. 337ra63 - 337ra63
Niemann-Pick disease type C (NPC) is a fatal, neurodegenerative, cholesterol storage disorder. With new therapeutics in clinical trials, it is imperative to... 
Journal Article
Cancer Immunology Research, ISSN 2326-6066, 01/2019, Volume 7, Issue 1, pp. 113 - 122
Preventive vaccination against tumor-associated endogenous antigens is considered to be an attractive strategy for the induction of a curative immune response... 
IMMUNE-RESPONSE | PROTEIN | EPITHELIAL-CELLS | ONCOLOGY | IMMUNOTHERAPY | INDUCTION | IMMUNOLOGY | PHASE-I | EXPRESSION | SYNTHETIC ANTITUMOR VACCINES | CANCER VACCINE | SELF-TOLERANCE
Journal Article