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Methods in molecular biology (Clifton, N.J.), ISSN 1064-3745, 2013, Volume 982, pp. 175 - 186
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 2, p. e14724
MicroRNAs (miRNAs) are small, non-protein-coding RNA molecules that modulate gene translation. Their expression is altered in many central nervous system (CNS)... 
MIRNA EXPRESSION | TRAUMATIC BRAIN-INJURY | MULTIDISCIPLINARY SCIENCES | CEREBRAL-ARTERY OCCLUSION | TRANSIENT FOCAL ISCHEMIA | GENE-EXPRESSION | HYPOXIA | CANCER | MICROARRAY ANALYSIS | GROWTH-FACTOR-I | REAL-TIME | Astrocytes - drug effects | Neurons - pathology | Oxygen - pharmacology | Embryo, Mammalian | Astrocytes - pathology | Brain Ischemia - genetics | Cells, Cultured | Gene Expression Regulation, Developmental - drug effects | Brain Ischemia - metabolism | Rats | MicroRNAs - metabolism | Brain Ischemia - embryology | Gene Expression Profiling | Glucose - pharmacology | Rats, Sprague-Dawley | Pregnancy | Animals | Time Factors | Brain Ischemia - pathology | Female | MicroRNAs - genetics | Neurons - metabolism | Neurons - drug effects | Astrocytes - metabolism | Brain | MicroRNA | Ischemia | Neurons | Analysis | Genes | Genetic translation | Traumatic brain injury | Disease | Insulin-like growth factor I | Brain cancer | Spatial discrimination | Central nervous system | Science | Neurosurgery | Kinases | Neuroprotective agents | Proteins | Reperfusion | Coding | Rodents | Conditioning | Growth factors | Injuries | Injury analysis | Therapeutic applications | Astrocytes | Fetuses | Cortex | MiRNA | Cultures | Gene expression | Insulin | Ribonucleic acids | MicroRNAs | Morphology | Stem cells | Hypoxia | Laboratory animals | Brain injury
Journal Article
Nature, ISSN 0028-0836, 08/2001, Volume 412, Issue 6847, pp. 641 - 647
Erythropoietin, a kidney cytokine regulating haematopoiesis (the production of blood cells), is also produced in the brain after oxidative or nitrosative... 
CELLS | OXIDATIVE STRESS | ACTIVATION | INHIBITION | INDUCED APOPTOSIS | MULTIDISCIPLINARY SCIENCES | HIPPOCAMPAL | NITRIC-OXIDE | GENE-EXPRESSION | TRANSCRIPTION FACTOR | CYTOKINE RECEPTORS
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2013, Volume 8, Issue 7, p. e68281
Ischemic stroke is the leading cause of serious, long-term adult disability and is associated with sensorimotor and cognitive impairments due to neuronal... 
MAMMALIAN TARGET | COMPLEX | PROTEIN | AMYLOID-BETA | MULTIDISCIPLINARY SCIENCES | INVOLVEMENT | GROWTH | MECHANISMS | DEATH | ISCHEMIC-STROKE | MTOR | TOR Serine-Threonine Kinases - metabolism | Embryo, Mammalian | Humans | Multiprotein Complexes - genetics | Neurons - cytology | Mechanistic Target of Rapamycin Complex 2 | Cerebral Cortex - cytology | Cerebral Cortex - metabolism | Oxygen - metabolism | Mechanistic Target of Rapamycin Complex 1 | Multiprotein Complexes - antagonists & inhibitors | TOR Serine-Threonine Kinases - antagonists & inhibitors | Multiprotein Complexes - metabolism | Neuroprotective Agents - pharmacology | TOR Serine-Threonine Kinases - genetics | Neurons - metabolism | Cerebral Cortex - drug effects | Neurons - drug effects | Cell Survival - drug effects | Signal Transduction | Gene Expression Regulation | Rats | Stroke - drug therapy | Rats, Sprague-Dawley | Sirolimus - pharmacology | Glucose - deficiency | Stroke - metabolism | Animals | Models, Biological | Primary Cell Culture | Stroke (Disease) | Rapamycin | Dosage and administration | Drug therapy | Neurons | Analysis | TOR protein | Neuroprotection | Oxidative stress | Phosphorylation | Medical services | Cognitive ability | Science | Neurosurgery | Kinases | Neuroprotective agents | Autophagy | t-Plasminogen activator | Proteins | Reperfusion | Ischemia | Neurodegeneration | Nutrient status | Sensorimotor system | Degeneration | Neurological disorders | Recombinant | Deprivation | Stroke | Cell survival | Cortex | Patients | Neurological diseases | Energy balance | Protein synthesis | Nutrient availability | Viability | Apoptosis
Journal Article
Journal of Neurotrauma, ISSN 0897-7151, 01/2013, Volume 30, Issue 1, pp. 55 - 66
Journal Article
Neuroscience journal, ISSN 2314-4262, 2019, Volume 2019, pp. 2831501 - 12
After traumatic brain injury (TBI), multiple ongoing processes contribute to worsening and spreading of the primary injury to create a secondary injury. One... 
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2004, Volume 101, Issue 26, pp. 9855 - 9860
Erythropoietin (EPO) and insulin-like growth factor I (IGF-I) are cytokines that inhibit neuronal apoptosis. However, their maximal antiapoptotic effect, even... 
Signal transduction | Biological Sciences | Phosphorylation | Neuroscience | Receptors | Insults | Cytokines | Neurons | Cultured cells | Epics | Apoptosis | Akt (protein kinase B) | Phosphatidylinositol 3-kinase | X-linked inhibitor of apoptosis protein | Caspase-3 | P85 SUBUNIT | BRAIN-INJURY | PROTEIN-KINASE | MULTIDISCIPLINARY SCIENCES | RETINAL NEURONS | apoptosis | CELL-SURVIVAL | NITRIC-OXIDE | CENTRAL-NERVOUS-SYSTEM | BINDING-SITES | phosphatidylinositol 3-kinase | caspase-3 | METHYL-D-ASPARTATE | Erythropoietin - pharmacology | Insulin-Like Growth Factor I - pharmacology | Apoptosis - drug effects | Humans | Neurons - cytology | Phosphatidylinositol 3-Kinases - metabolism | Cerebral Cortex - cytology | N-Methylaspartate - antagonists & inhibitors | N-Methylaspartate - pharmacology | Caspases - metabolism | Neuroprotective Agents - pharmacology | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Caspase 3 | Neurons - metabolism | Phosphorylation - drug effects | Neurons - drug effects | Protein-Serine-Threonine Kinases - metabolism | Proto-Oncogene Proteins - metabolism | Cell Survival - drug effects | Proto-Oncogene Proteins - antagonists & inhibitors | Cells, Cultured | Rats | Rats, Sprague-Dawley | Drug Synergism | Proto-Oncogene Proteins c-akt | Animals | Neurons - enzymology | N-Methylaspartate - toxicity | Phosphatidylinositol | Research | Erythropoietin | Protein kinases
Journal Article
Current Medicinal Chemistry, ISSN 0929-8673, 04/2015, Volume 22, Issue 10, pp. 1302 - 1309
Granulocyte-colony stimulating factor (G-CSF) has a multimodal neuroprotective profile and the cumulative preclinical data from numerous translational studies... 
Journal Article