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administration, oral (10) 10
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infliximab (10) 10
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growth-factor-beta (9) 9
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1. Full Text Expanded allogeneic adipose-derived mesenchymal stem cells (Cx601) for complex perianal fistulas in Crohn's disease: a phase 3 randomised, double-blind controlled trial
by Panés, Julián, Prof|García-Olmo, Damián, MD|Van Assche, Gert, Prof|Colombel, Jean Frederic, Prof|Reinisch, Walter, Prof|Baumgart, Daniel C, Prof|Dignass, Axel, Prof|Nachury, Maria, MD|Ferrante, Marc, Prof|Kazemi-Shirazi, Lili, Prof|Grimaud, Jean C, Prof|de la Portilla, Fernando, Prof|Goldin, Eran, Prof|Richard, Marie Paule, MD|Leselbaum, Anne, MD|Danese, Silvio, Prof and ADMIRE CD Study Grp Collaborators and ADMIRE CD Study Group Collaborators
Lancet, The, ISSN 0140-6736, 2016, Volume 388, Issue 10051, pp. 1281 - 1290
Summary Background Complex perianal fistulas in Crohn's disease are challenging to treat. Allogeneic, expanded, adipose-derived stem cells (Cx601) are a... 
Internal Medicine | 6-MERCAPTOPURINE | ANAL FISTULAS | MEDICINE, GENERAL & INTERNAL | THERAPY | ACTIVITY INDEX | METRONIDAZOLE | INFLIXIMAB | CIPROFLOXACIN | REMISSION | LONG | Double-Blind Method | Rectal Fistula - etiology | Europe | Humans | Middle Aged | Rectal Fistula - surgery | Male | Treatment Outcome | Combined Modality Therapy | Evidence-Based Medicine | Transplantation, Homologous | Crohn Disease - complications | Rectal Fistula - therapy | Rectal Fistula - pathology | Mesenchymal Stromal Cells | Adult | Female | Aged | Israel | Adipose Tissue | Mesenchymal Stem Cell Transplantation | Medical colleges | Hospitals | Gastrointestinal diseases | Stem cells | Clinical trials | Fistula | Health aspects | Spain | Tumor necrosis factor-TNF | Inflammation | Medical treatment | Crohns disease | Index Medicus | Abridged Index Medicus
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2. Full Text Critical Evaluation of Current Concepts and Moving to New Horizons in the Management of IBD
by Dignass, Axel
Digestive Diseases, ISSN 0257-2753, 09/2015, Volume 33, Issue 1, pp. 1 - 1
Further Section | GASTROENTEROLOGY & HEPATOLOGY
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3. Full Text European Consensus on the Diagnosis and Management of Iron Deficiency and Anaemia in Inflammatory Bowel Diseases
by Dignass, Axel U and Gasche, Christoph and Bettenworth, Dominik and Birgegård, Gunnar and Danese, Silvio and Gisbert, Javier P and Gomollon, Fernando and Iqbal, Tariq and Katsanos, Konstantinos and Koutroubakis, Ioannis and Magro, Fernando and Savoye, Guillaume and Stein, Jürgen and Vavricka, Stephan and ECCO and European Crohn’s and Colitis Organisation [ECCO] and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Uppsala universitet and Institutionen för medicinska vetenskaper and Hematologi
Journal of Crohn's and Colitis, ISSN 1873-9946, 3/2015, Volume 9, Issue 3, pp. 211 - 222
transferrin saturation | anaemia | anaemia of chronic disease | Crohn's disease | iron deficiency | inflammatory bowel disease | Crohn’s disease | Ulcerative colitis | THIOPURINE S-METHYLTRANSFERASE | CROHNS-DISEASE | INTRAVENOUS IRON | ULCERATIVE-COLITIS | AUTOIMMUNE HEMOLYTIC-ANEMIA | RANDOMIZED CONTROLLED-TRIAL | ORAL IRON | STFR/LOG FERRITIN INDEX | PLACEBO-CONTROLLED TRIAL | SOLUBLE TRANSFERRIN RECEPTOR | GASTROENTEROLOGY & HEPATOLOGY | Hematinics - therapeutic use | Erythrocyte Transfusion | Anemia, Iron-Deficiency - etiology | Humans | Trace Elements - therapeutic use | Anemia - diagnosis | Anemia - therapy | Combined Modality Therapy | Vitamins - therapeutic use | Anemia, Iron-Deficiency - therapy | Iron - therapeutic use | Anemia, Iron-Deficiency - diagnosis | Iron - deficiency | Inflammatory Bowel Diseases - complications | Dietary Supplements | Anemia - etiology | Inflammatory Bowel Diseases - therapy | Index Medicus | Life Sciences | Human health and pathology | Hépatology and Gastroenterology | Medical and Health Sciences | Hematology | Medicin och hälsovetenskap | Klinisk medicin | Clinical Medicine | Hematologi
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4. Full Text Mo1897 Efficacy and Safety of Granulocyte, Monocyte/Macrophage Adsorptive Apheresis in Steroid-Dependent Active UC With Insufficient Response or Intolerance to Immunosuppressants and/or Biological Therapies (The ART trial)
by Dignass, Axel|Akbar, Ayesha|Bonaz, Bruno L
Gastroenterology, ISSN 0016-5085, 2016, Volume 150, Issue 4, pp. S810 - S810
Gastroenterology and Hepatology | Clinical trials | Immunosuppressive agents
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5. Full Text Su1840 The Efficacy of Intravenous Iron Therapy in IBD Patients With Active Disease Is Not Influenced by the Degree of Inflammatory Activity
by Walper, Andreas|Dignass, Axel|Stein, Jürgen
Gastroenterology, ISSN 0016-5085, 2016, Volume 150, Issue 4, pp. S567 - S567
Gastroenterology and Hepatology
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6. Full Text P044 The comparative safety of different intravenous iron preparations in inflammatory bowel disease
: A systematic review and network meta-analysis
by Ayşegül, Aksan and Hatice, Işık and Karima, Farrag and Axel, Dignass and Jürgen, Stein
The American Journal of Gastroenterology, ISSN 0002-9270, 07/2019, Volume 114, p. S12
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7. Full Text P043 Update of a network meta-analysis of efficacy and safety of different intravenous iron compounds in patients with IBD and anemia
by Ayşegül, Aksan and Hatice, Işık and Heinfried, Radeke and Axel, Dignass and Jürgen, Stein
The American Journal of Gastroenterology, ISSN 0002-9270, 07/2019, Volume 114, p. S12
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8. Full Text UEG Standards and Guidelines: A UEG initiative to reduce health inequalities across Europe
by Dignass, Axel
United European Gastroenterology Journal, ISSN 2050-6406, 8/2016, Volume 4, Issue 4, pp. 621 - 622
GASTROENTEROLOGY & HEPATOLOGY | Special section on Fibrosis in Crohn's disease and inflammatory bowel disorders
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9. Complementary therapies in inflammatory bowel diseases
by Esters, Philip and Dignass, Axel
Current Drug Targets, ISSN 1389-4501, 01/2014, Volume 15, Issue 11, pp. 1079 - 1088
Complementary and alternative therapies (CAM) are defined as therapies that are presently not considered part of conventional medical practice. They are termed... 
Complementary therapies | Phosphatidylcholine | Probiotics | Ayurveda | Inflammatory bowel diseases | Traditional chinese medicine | GERMINATED BARLEY FOODSTUFF | inflammatory bowel diseases | CROHNS-DISEASE | RANDOMIZED CONTROLLED-TRIAL | traditional chinese medicine | WORMWOOD ARTEMISIA-ABSINTHIUM | complementary therapies | phosphatidylcholine | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | ACTIVE ULCERATIVE-COLITIS | PLACEBO-CONTROLLED TRIAL | TRICHURIS-SUIS THERAPY | MAINTAINING REMISSION | probiotics | POUCH-ANAL ANASTOMOSIS
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10. Full Text Transgenic Mice Rich in Endogenous Omega-3 Fatty Acids Are Protected from Colitis
by Christian A. Hudert and Karsten H. Weylandt and Yan Lu and Jingdong Wang and Song Hong and Axel Dignass and Charles N. Serhan and Jing X. Kang
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2006, Volume 103, Issue 30, pp. 11276 - 11281
Omega-6 (n-6) and omega-3 (n-3) polyunsaturated fatty acids (PUFA) are the precursors of potent lipid mediators and play an important role in regulation of... 
Omega 6 fatty acids | Inflammatory bowel diseases | Antiinflammatories | Cytokines | Transgenic animals | Lipids | Inflammation | Mice | Colitis | Fatty acids | Inflammatory bowel disease | Protections | Resolvins | Lipid mediators | DOCOSATRIENES | MULTIDISCIPLINARY SCIENCES | RECEPTOR | INDUCTION | protectins | inflammatory bowel disease | lipid mediators | NECROSIS-FACTOR | INFLAMMATORY-BOWEL-DISEASE | THERAPY | inflammation | ROLES | resolvins | FISH-OIL | EXPRESSION | Fatty Acids, Omega-3 - metabolism | Models, Chemical | Colitis - genetics | Mice, Inbred C57BL | Colitis - pathology | Mice, Transgenic | NF-kappa B - metabolism | Dinoprostone - metabolism | Lipids - chemistry | Animals | Ultraviolet Rays | Eicosanoids - metabolism | Mass Spectrometry | Leukotriene B4 - metabolism | Inflammation - prevention & control | Colitis - prevention & control | Prevention | Genetically modified mice | Research | Health aspects | Omega-3 fatty acids | Proteins | Hormones | Rodents | Index Medicus | Biological Sciences
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11. Full Text 3rd European Evidence-based Consensus on the Diagnosis and Management of Crohn's Disease 2016: Part 2: Surgical Management and Special Situations
by Gionchetti, Paolo and Dignass, Axel and Danese, Silvio and Magro Dias, Fernando José and Rogler, Gerhard and Lakatos, Péter Laszlo and Adamina, Michel and Ardizzone, Sano and Buskens, Christianne J and Sebastian, Shaji and Laureti, Silvio and Sampietro, Gianluca M and Vucelic, Boris and van der Woude, C. Janneke and Barreiro-de Acosta, Manuel and Maaser, Christian and Portela, Francisco and Vavricka, Stephan R and Gomollón, Fernando and ECCO
Journal of Crohn s & colitis, ISSN 1873-9946, 2017, Volume 11, Issue 2, pp. 135 - 149
This paper is the second in a series of two publications relating to the European Crohn's and Colitis Organisation [ECCO] evidence-based consensus on the... 
Anti-integrins | Anti-TNFs | Budesonide | Immunosuppressant | Treatment | Biologics | Thiopurine | Crohn's disease | Diagnosis | Investigations | Steroids | budesonide | treatment | anti-TNFs | biologics | thiopurine | anti-integrins | diagnosis | investigations | immunosuppressant | steroids | GASTROENTEROLOGY & HEPATOLOGY | Crohn Disease - pathology | Europe | Humans | Crohn Disease - surgery | Systemic Inflammatory Response Syndrome - etiology | Crohn Disease - physiopathology | Disease Management | Anal Canal - pathology | Systemic Inflammatory Response Syndrome - diagnosis | Crohn Disease - complications | Digestive System Surgical Procedures - methods | Systemic Inflammatory Response Syndrome - therapy | Index Medicus
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12. Full Text Functional Capacity Of Gastrointestinal Cancer Patients - A Pre-therapy Comparison To Breast Cancer Patients And Healthy Women
: 1000 Board #179 May 31 2
by Vogt, Lutz and Stücher, Katrin and Bolling, Claus and Dignass, Axel and Banzer, Winfried
Medicine & Science in Sports & Exercise, ISSN 0195-9131, 05/2017, Volume 49, pp. 269 - 270
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13. Full Text Selective non-steroidal glucocorticoid receptor agonists attenuate inflammation but do not impair intestinal epithelial cell restitution in vitro
by Reuter, Kerstin C and Loitsch, Stefan M and Dignass, Axel U and Steinhilber, Dieter and Stein, Jürgen
PLoS ONE, ISSN 1932-6203, 01/2012, Volume 7, Issue 1, pp. e29756 - e29756
Introduction: Despite the excellent anti-inflammatory and immunosuppressive action of glucocorticoids (GCs), their use for the treatment of inflammatory bowel... 
PLANT-ORIGIN | MEDICAL THERAPY | BIOLOGY | GROWTH-FACTOR | REPAIR MECHANISMS | KAPPA-B | SIGNAL-REGULATED KINASE | MODULATION | MOLECULAR-MECHANISMS | BOWEL-DISEASE | WOUND REPAIR | Transcription, Genetic - drug effects | Intestinal Mucosa - metabolism | Gene Silencing - drug effects | Apoptosis - drug effects | Humans | Transcriptional Activation - drug effects | Benzofurans - pharmacology | Receptors, Glucocorticoid - metabolism | Intestinal Mucosa - drug effects | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Receptors, Glucocorticoid - agonists | Intestinal Mucosa - cytology | Cell Nucleus - metabolism | Inflammation - drug therapy | Wound Healing - drug effects | Cell Line | Benzofurans - therapeutic use | Benzoxazines - adverse effects | Epidermal Growth Factor - metabolism | Benzofurans - adverse effects | Benzoxazines - therapeutic use | Anti-Inflammatory Agents, Non-Steroidal - adverse effects | MAP Kinase Signaling System - drug effects | Mitogen-Activated Protein Kinase 3 - metabolism | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Active Transport, Cell Nucleus - drug effects | Benzoxazines - pharmacology | Cell Proliferation - drug effects | Cell Nucleus - drug effects | Transforming Growth Factor beta - metabolism | Mitogen-Activated Protein Kinase 1 - metabolism | Care and treatment | Dexamethasone | Gastrointestinal diseases | Bone morphogenetic proteins | Transforming growth factors | Comparative analysis | Wounds and injuries | Steroids | Cell proliferation | Flow cytometry | Inflammatory bowel diseases | Glucocorticoids | Peptides | Epithelial cells | Activation | Kinases | Assaying | Cell adhesion & migration | MAP kinase phosphatase | Proteins | Signal transduction | Epidermal growth factor | Reporter gene | Intestine | Rodents | Fibroblasts | Tumor necrosis factor-TNF | Inhibition | Interleukin 8 | Deoxyribonucleic acid--DNA | Translocation | Compound A | NF-κB protein | Wound healing | Antiinflammatory agents | Secretion | Medical treatment | Health risks | Extracellular signal-regulated kinase | MAP kinase | Inflammation | Gene expression | Cytometry | Signaling | Immunosuppression | Side effects | Gene flow | Protein synthesis | Nitric oxide | Ligands | Healing | In vitro methods and tests | Apoptosis | Pharmaceuticals | Index Medicus | Deoxyribonucleic acid | DNA
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14. Full Text 1073 Analytical Performance of a New iPhone-Based Patient Monitoring System Comparable to ELISA for Measuring Fecal Calprotectin in IBD Patients
by Wintgens, Karl F.|Wulandari, A|Dignass, Axel|Hartmann, Franz|Stein, Jürgen
Gastroenterology, ISSN 0016-5085, 2016, Volume 150, Issue 4, pp. S212 - S212
Gastroenterology and Hepatology | Measurement | Patient monitoring equipment | Enzyme-linked immunosorbent assay | Smart phones
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15. Full Text Systematic review with meta-analysis: real-world effectiveness and safety of vedolizumab in patients with inflammatory bowel disease
by Schreiber, Stefan and Dignass, Axel and Peyrin-Biroulet, Laurent and Hather, Greg and Demuth, Dirk and Mosli, Mahmoud and Curtis, Rebecca and Khalid, Javaria Mona and Loftus Jr, Edward Vincent
Journal of Gastroenterology, ISSN 0944-1174, 9/2018, Volume 53, Issue 9, pp. 1048 - 1064
Selective patient recruitment can produce discrepancies between clinical trial results and real-world effectiveness.A systematic literature review and... 
Inflammatory bowel disease | Medicine & Public Health | Colorectal Surgery | Hepatology | Real-world effectiveness | Gastroenterology | Abdominal Surgery | Vedolizumab | Surgical Oncology | Ulcerative colitis | Crohn’s disease | BIOLOGIC-NAIVE PATIENTS | CROHNS-DISEASE | ULCERATIVE-COLITIS | ANTI-TNF THERAPY | Crohn's disease | REFRACTORY IBD PATIENTS | MAINTENANCE THERAPY | EVIDENCE-BASED CONSENSUS | INDUCTION THERAPY | POSTOPERATIVE INFECTIOUS COMPLICATIONS | GASTROENTEROLOGY & HEPATOLOGY | PRIMARY SCLEROSING CHOLANGITIS | Medical research | Care and treatment | Corticosteroids | Safety and security measures | Analysis | Medicine, Experimental | Literature reviews | Corticoids | Inflammatory bowel diseases | Intestine | Mucosa | Surgery | Clinical trials | Systematic review | Remission | Safety | Patients | Index Medicus | Original —Alimentary Tract
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16. Biosimilars bei Chronisch Entzündlichen Darmerkrankungen (CED): Erfahrungen und Einschätzungen deutscher Gastroenterologen
by Bokemeyer, Bernd and Dignaß, Axel and Schreiber, Stefan
Zeitschrift fur Gastroenterologie, ISSN 0044-2771, 04/2017, Volume 55, Issue 4, pp. 369 - 374
survey | Crohn's disease | ulcerative colitis | inflammatory bowel disease | biosimilars
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17. Full Text Luminal esophageal temperature predicts esophageal lesions after second-generation cryoballoon pulmonary vein isolation
by Fürnkranz, Alexander, MD|Bordignon, Stefano, MD|Schmidt, Boris, MD, FHRS|Böhmig, Michael, MD|Böhmer, Marie-Christine, MD|Bode, Frank, MD|Schulte-Hahn, Britta, MD|Nowak, Bernd, MD|Dignaß, Axel U., MD|Chun, Julian K.R., MD
Heart Rhythm, ISSN 1547-5271, 2013, Volume 10, Issue 6, pp. 789 - 793
Background The novel second-generation cryoballoon (CB) facilitates pulmonary vein isolation (PVI) by improved surface cooling. The impact of this redesign on... 
Cardiovascular | Electrophysiology | Balloon | Arrhythmia | Ablation | Atrial fibrillation | CARDIAC & CARDIOVASCULAR SYSTEMS | CATHETER ABLATION | ATRIAL-FIBRILLATION | Humans | Middle Aged | Male | Fluoroscopy | Gastroscopy | Body Temperature | Atrial Fibrillation - surgery | Cryosurgery - methods | Equipment Design | Esophagoscopy | Esophageal Diseases - etiology | Cryosurgery - instrumentation | Female | Aged | Pulmonary Veins - surgery | Cryosurgery - adverse effects | Electrophysiologic Techniques, Cardiac | Esophageal Diseases - diagnosis | Ablation (Surgery) | Weather forecasting | Index Medicus
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18. Full Text Third European evidence-based consensus on diagnosis and management of ulcerative colitis. Part 2: Current management
by Harbord, Marcus and Eliakim, Rami and Bettenworth, Dominik and Karmiris, Konstantinos and Katsanos, Konstantinos and Kopylov, Uri and Kucharzik, Torsten and Molnár, Tamás and Raine, Tim and Sebastian, Shaji and de Sousa, Helena Tavares and Dignass, Axel and Carbonnel, Franck and European Crohn's Colitis Org ECCO and European Crohn’s and Colitis Organisation [ECCO] and for the European Crohn’s and Colitis Organisation [ECCO]
Journal of Crohn's and Colitis, ISSN 1873-9946, 2017, Volume 11, Issue 7, pp. 769 - 784
GASTROENTEROLOGY & HEPATOLOGY | Colon, Sigmoid | Humans | Immunosuppressive Agents - therapeutic use | Proctitis - drug therapy | Colon, Descending | Adrenal Cortex Hormones - therapeutic use | Evidence-Based Medicine | Remission Induction | Consensus | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Gastrointestinal Agents - therapeutic use | Mesalamine - therapeutic use | Maintenance Chemotherapy | Colitis, Ulcerative - drug therapy | Drug Therapy, Combination | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Adrenal Cortex Hormones - administration & dosage | Biological Products - therapeutic use | Mesalamine - administration & dosage | Index Medicus
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