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PLoS ONE, ISSN 1932-6203, 10/2014, Volume 9, Issue 10, pp. e111385 - e111385
Journal Article
Journal Article
Cell, ISSN 0092-8674, 1997, Volume 91, Issue 2, pp. 197 - 208
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 01/2010, Volume 38, Issue 1, pp. 16 - 24
Monkeys have been proposed as an animal model to predict the magnitude of human clinical drug-drug interactions caused by CYP3A4 enzyme induction. To evaluate... 
VITRO | CYTOCHROME-P450 | INHIBITION | ENZYME | METABOLISM | RHESUS-MONKEY | LIVER | PHARMACOLOGY & PHARMACY | ST-JOHNS-WORT | MODEL | DRUG-INTERACTION | Transcriptional Activation - genetics | Gene Expression - genetics | Humans | Middle Aged | Transcriptional Activation - drug effects | Macaca fascicularis | Male | Macaca mulatta | Phloroglucinol - blood | Cytochrome P-450 CYP3A - genetics | Bridged Bicyclo Compounds - blood | Models, Animal | Amino Acid Sequence | Cell Survival - drug effects | Cytochrome P-450 CYP3A - biosynthesis | Bridged Bicyclo Compounds - pharmacology | Terpenes - blood | Enzyme Induction - genetics | Terpenes - pharmacokinetics | Midazolam - blood | Cytochrome P-450 CYP3A - metabolism | Cell Line, Tumor | Bridged Bicyclo Compounds - pharmacokinetics | Rifampin - pharmacology | Pregnane X Receptor | Hepatocytes - enzymology | Hypericum - chemistry | Rifampin - pharmacokinetics | Receptors, Steroid - metabolism | Gene Expression - drug effects | Rifampin - blood | Plant Extracts - blood | Molecular Sequence Data | Hepatocytes - metabolism | Xenobiotics - pharmacokinetics | Terpenes - pharmacology | Drug Interactions - genetics | Transfection | Cloning, Molecular | Phloroglucinol - pharmacology | Enzyme Induction - drug effects | Adult | Female | Hepatocytes - drug effects | Cell Line | Midazolam - pharmacokinetics | Sequence Homology, Amino Acid | Animals | Receptors, Steroid - genetics | Plant Extracts - pharmacokinetics | Midazolam - metabolism | Phloroglucinol - analogs & derivatives | Phloroglucinol - pharmacokinetics
Journal Article
Cell, ISSN 0092-8674, 11/1996, Volume 87, Issue 5, pp. 803 - 809
Two cyclooxygenase isozymes catalyze conversion of arachidonic acid to prostaglandin H : constitutive COX-1 and inducible COX-2. To assess the role of COX-2 in... 
EPITHELIAL-CELLS | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | APC GENE | NEOPLASIA | BIOCHEMISTRY & MOLECULAR BIOLOGY | HUMAN COLON-CANCER | PROSTAGLANDIN-G/H SYNTHASE | FAMILIAL ADENOMATOUS POLYPOSIS | ASPIRIN | EXPRESSION | MAJOR MODIFIER | CELL BIOLOGY
Journal Article
Journal Article
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2014, Volume 9, Issue 10
P2Y.sub.6, a purinergic receptor for UDP, is enriched in atherosclerotic lesions and is implicated in pro-inflammatory responses of key vascular cell types and... 
Atherosclerosis | Angiotensin | Aneurysms | Inflammation | Macrophages
Journal Article
Cancer Research, ISSN 0008-5472, 02/2011, Volume 71, Issue 3, pp. 801 - 811
Agonist monoclonal antibodies (mAb) to the immune costimulatory molecule CD137, also known as 4-1BB, are presently in clinical trials for cancer treatment on... 
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/2000, Volume 275, Issue 50, pp. 39543 - 39554
Journal Article
Cancer Research, ISSN 0008-5472, 03/2008, Volume 68, Issue 6, pp. 1683 - 1690
Bin3 encodes an evolutionarily conserved and ubiquitously expressed member of the BAR superfamily of curved membrane and GTPase-binding proteins, which... 
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 04/2002, Volume 277, Issue 15, p. 12970
The BAH genomic locus encodes three distinct proteins: junctin, humbug, and BAH. All three proteins share common exons, but differ significantly based upon the... 
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/2000, Volume 275, Issue 50, p. 39543
The mouse aspartyl β-hydroxylase gene ( Asph, BAH ) has been cloned and characterized. The mouse BAH gene spans 200 kilobase pairs of genomic DNA and contains... 
Journal Article
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