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Nature, ISSN 0028-0836, 2014, Volume 514, Issue 7521, pp. 187 - 192
The murine caspase-11 non-canonical inflammasome responds to various bacterial infections. Caspase-11 activation-induced pyroptosis, in response to cytoplasmic... 
ACTIVATION | GRAM-NEGATIVE BACTERIA | MULTIDISCIPLINARY SCIENCES | CYTOPLASMIC LPS | NLRP3 | LIPID IVA | MECHANISMS | PYROPTOSIS | PROTEINS | TLR4 | LIPOPOLYSACCHARIDE RECOGNITION | Surface Plasmon Resonance | Epithelial Cells - metabolism | Caspases - immunology | Humans | Lipopolysaccharides - metabolism | Substrate Specificity | Caspases, Initiator - genetics | Genetic Complementation Test | Lipopolysaccharides - immunology | Caspases - metabolism | Caspases, Initiator - metabolism | Protein Multimerization - genetics | Cell Death - drug effects | Caspases - chemistry | Epithelial Cells - cytology | Caspases, Initiator - immunology | Lipid A - metabolism | Caspases - genetics | Cells, Cultured | Rhodobacter sphaeroides - chemistry | Mutant Proteins - metabolism | Keratinocytes - cytology | Macrophages - cytology | Enzyme Activation - drug effects | Immunity, Innate | Necrosis - chemically induced | Macrophages - metabolism | Animals | Rhodobacter sphaeroides - immunology | Keratinocytes - metabolism | Caspases, Initiator - chemistry | Mutant Proteins - chemistry | Lipopolysaccharides - pharmacology | Protein Binding | Macrophages - drug effects | Mice | Enzyme Activation - genetics | Inflammation - enzymology | Protein Multimerization - drug effects | Lipids | Septic shock | Immune response | Health aspects | Analysis | Proteins | Salmonella | Bacterial infections | E coli | Bacteria | Cytotoxicity | Mutation | Apoptosis | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 07/2016, Volume 535, Issue 7610, pp. 111 - 116
Journal Article
The EMBO Journal, ISSN 0261-4189, 08/2018, Volume 37, Issue 15, pp. e100067 - n/a
Inflammasome‐activated caspase‐1, caspase‐11, caspase‐4, and caspase‐5 cleave GSDMD to unleash its N‐terminal gasdermin‐N domain ( GSDMD N term ) that... 
GSDMD | CASPASE-11 | CLEAVAGE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | Humans | Caspase 1 | Pyroptosis | Oligomers | Caspase | Atomic force microscopy | Membranes | Microscopy | Pore formation | Index Medicus | Views | Immunology | Autophagy & Cell Death
Journal Article
Cell, ISSN 0092-8674, 01/2017, Volume 168, Issue 3, pp. 544 - 544.e1
This SnapShot depicts how the noncanonical inflammasome pathway is initiated and activated, as well as its effector mechanism in triggering pyroptosis and... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | Infection - metabolism | Animals | Caspases - metabolism | Inflammasomes - metabolism | Signal Transduction | Infection - immunology | Humans | Inflammasomes - immunology | Immunity, Innate | Index Medicus
Journal Article
中国人才, ISSN 1003-4072, 2017, Issue 7, pp. 10 - 13
2017年4月1日,党中央作出设立河北雄安新区的重要决定,京津冀协同发展再度成为世人关注的焦点。 
党中央 | 京津冀 | 人才一体化 | 协同发展 | 一体化发展
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 11/2014, Volume 136, Issue 42, pp. 14694 - 14697
Journal Article
Nature, ISSN 0028-0836, 09/2018, Volume 561, Issue 7721, pp. 122 - 126
Immune recognition of pathogen-associated molecular patterns (PAMPs) by pattern recognition receptors often activates proinflammatory NF-kappa B signalling(1).... 
PROTEIN | PATHWAY | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | SECRETION SYSTEM | TIFA | INFLAMMASOME | RHO GTPASES | CHEMICAL-SYNTHESIS | IDENTIFICATION | FAMILY | Protein Kinases - metabolism | Inflammation - pathology | Disaccharides - metabolism | Cytosol - immunology | Burkholderia cenocepacia - genetics | Crystallography, X-Ray | Male | NF-kappa B - metabolism | Burkholderia Infections - enzymology | Cytosol - enzymology | Adenosine Diphosphate Sugars - immunology | Burkholderia Infections - pathology | Female | Burkholderia cenocepacia - immunology | Yersinia pseudotuberculosis - immunology | Burkholderia Infections - immunology | Pathogen-Associated Molecular Pattern Molecules - metabolism | Immunomodulation | Mice, Inbred C57BL | Immunologic Factors - immunology | Models, Molecular | Pathogen-Associated Molecular Pattern Molecules - immunology | Inflammation - immunology | Immunity, Innate | Adenosine Diphosphate Sugars - metabolism | Gene Editing | Yersinia pseudotuberculosis - genetics | Animals | Yersinia pseudotuberculosis - metabolism | Burkholderia cenocepacia - metabolism | CRISPR-Cas Systems | Mice | Enzyme Activation | Immunologic Factors - metabolism | Inflammation - enzymology | Cytokines - biosynthesis | Microbiological research | Cell receptors | Physiological aspects | Adenosine diphosphate | Bacteria | Research | Phosphotransferases | Sugars | Monosaccharides | Immune system | Phosphorylation | Infections | Activation | Genomes | Kinases | ADP | Cytosol | Proteins | Pseudotuberculosis | Receptors | Metabolites | E coli | Forkhead protein | Chemical synthesis | Crystal structure | Pathogens | CRISPR | NF-κB protein | Bacterial infections | Cytokines | Secretion | Inflammation | Pattern recognition | Heptose | Index Medicus
Journal Article
Science of the Total Environment, ISSN 0048-9697, 05/2019, Volume 666, pp. 1048 - 1057
Journal Article
产业与科技论坛, ISSN 1673-5641, 2017, Volume 16, Issue 18, pp. 35 - 36
在国家着重提振文化产业和京津冀区域经济协同发展的政策大背景下,结合对京津冀各地文化产业的分析与研究的基础上,以文化产业自身特点衍生出文化产业发展的政策引导、资源共享、科技创新、人才供应等关键因素以及各要素之间的作用规律,对京津冀文化产业提升发展路径提出可资借鉴的切实措施。 
京津冀 | 文化产业 | 发展路径
Journal Article
中国人才, ISSN 1003-4072, 2015, Issue 19, pp. 21 - 23
8月10日至16日,为期一周的“北京冀高层次人才联合休假活动”在河北省张家口市举行。这是京津冀协同发展战略实施以来,北京、天津、河北三地党委组织部首次携手联合举办专家休假活动。来自三地的52位高层次专家,感受领略了张家口地区的大好河山、悠久历史和风土人情。 
党委组织 | 京津冀 | 人才智力 | 协同发展战略 | 张家口地区 | 张家口市 | 风土人情 | 人才联合
Journal Article
山东体育学院学报, ISSN 1006-2076, 2016, Volume 32, Issue 3, pp. 49 - 52
网球产业的协同发展,对京津冀地区的体育产业和经济繁荣具有现实意义.对京津冀地区网球产业进行SWOT分析,提出京津冀三地网球产业协同发展的对策:1 ) 实验三地网球产业要素市场一体化;2 )打造三地网球信息一体化;3 ) 实验网球教育培训一体化;4 )打造网球产业多元化. 
京津冀 | 协同发展 | 网球产业 | SWOT
Journal Article
现代商贸工业, ISSN 1672-3198, 2017, Volume 38, Issue 2, pp. 6 - 7
随着京津冀协同发展的深入,廊坊在承接产业转移的过程中发挥着越来越大优势,金融服务业作为支撑产业转移和经济发展的重要因素,如何有效的发挥更大的作用,是当下亟需解决的问题。面对金融服务业存在的问题,廊坊市应积极提高融资能力,优化调整金融结构,加快金融多元化创新,进而持续不断的实现金融服务业的可持续发展。 
金融服务 | 京津冀一体化 | 发展路径
Journal Article
Science of the Total Environment, ISSN 0048-9697, 10/2019, Volume 688, pp. 1137 - 1144
Alongside a trend in lower private-vehicle ownership and the growing popularity of the shared use economy, car sharing is emerging as an alternative travel... 
Life cycle assessment | GWP | GHG reduction | Electric vehicle | Transportation | Car sharing | ENERGY | EMISSIONS | MOBILITY | CHINA | ENVIRONMENTAL SCIENCES | IMPACTS | CONSUMPTION | Case studies | Global warming potential | Usage | Local transit | Transportation industry | Electric vehicles | Global warming
Journal Article
Molecular Cell, ISSN 1097-2765, 06/2019, Volume 74, Issue 5, pp. 922 - 935.e6
Enteropathogenic NleB and related type III effectors catalyze arginine GlcNAcylation of death domain (DD) proteins to block host defense, but the underlying... 
bacterial virulence | arginine modification | protein glycosylation | type III secretion system | glycosyltransferase | death receptor signaling | GlcNAcylation | death domain | bacteria-host interaction | Enzymes | Biological products | Arginine | Analysis | Crystals | Virulence (Microbiology) | Structure
Journal Article
中共中央党校学报, ISSN 1007-5801, 2016, Volume 20, Issue 3, pp. 74 - 79
Journal Article
北京观察, ISSN 1008-1208, 2016, Issue 8, pp. 33 - 33
京津冀地区冬季燃煤取暖向空气中排放大量烟尘,是雾霾的一个重要因素。数据显示,京津冀地区目前年煤炭消费总量为3.3亿吨标煤,占全球陆地面积不到0.3%,却燃烧了全球消费量6%的煤。北京、天津和河北PM2.5来源中,燃煤分别占比为22%、27%和28%。由此可见,燃煤是京津冀地区主要污染源之一。 
放大量 | 地域面积 | 地区经济 | 京津冀一体化 | 数据显示 | 煤炭消费总量 | 能源使用 | 农村地区 | 煤改气 | 集中供暖
Journal Article
北京观察, ISSN 1008-1208, 2016, Issue 8, p. 33
<正>京津冀地区冬季燃煤取暖向空气中排放大量烟尘,是雾霾的一个重要因素。数据显示,京津冀地区目前年煤炭消费总量为3.3亿吨标煤,占全球陆地面积不到0.3%,却燃烧了全球消费量6%的煤。北京、天津和河北PM2.5来源中,燃煤分别占比为22%、27%和28%。由此可见,燃煤是京津冀地区主要污染源之一。 
煤改气;煤炭消费总量;放大量;地区经济;京津冀一体化;能源使用;数据显示;集中供暖;农村地区;地域面积
Journal Article
现代商贸工业, ISSN 1672-3198, 2016, Volume 37, Issue 34, pp. 34 - 35
金融资本是区域经济发展的基础条件之一,良好的金融环境为区域经济发展提供了可靠的资金支撑。近年来,随着国家京津冀一体化战略升级,廊坊在承接京津产业转移,创新金融服务后台,服务区域经济发展过程中发挥着日益重要的作用。在具体操作层面上,可在完善后台服务基本功能的基础上,创新金融信息、金融研发,从而逐步打造区域性金融产业集群。 
总部基础功能 | 京津冀一体化 | 金融创新实验 | 金融后台服务
Journal Article
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