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Human Molecular Genetics, ISSN 0964-6906, 06/2014, Volume 23, Issue 11, pp. 2995 - 3007
Journal Article
British Journal of Clinical Pharmacology, ISSN 0306-5251, 03/2015, Volume 79, Issue 3, pp. 465 - 476
Journal Article
Neurobiology of Disease, ISSN 0969-9961, 2006, Volume 24, Issue 2, pp. 254 - 265
Expression of the Wnt antagonist Dickkopf-1 (DKK1) is induced during neurodegenerative processes associated with Alzheimer's Disease and brain ischemia.... 
GLYCOGEN-SYNTHASE KINASE-3-BETA | DICKKOPF PROTEINS | TCF TRANSCRIPTION FACTORS | WNT/BETA-CATENIN | ALZHEIMERS-DISEASE | AMYLOID-BETA-PEPTIDE | IN-VIVO | NEGATIVE MODULATOR | RECEPTOR-RELATED PROTEIN-6 | HIPPOCAMPAL-NEURONS | NEUROSCIENCES | Neurons - pathology | Phosphorylation | Rats, Wistar | Humans | Basal Nucleus of Meynert - physiopathology | Nerve Degeneration - physiopathology | Gliosis - chemically induced | Nerve Degeneration - genetics | tau Proteins - metabolism | Glycogen Synthase Kinase 3 beta | Male | Gliosis - physiopathology | Hippocampus - drug effects | Wnt Proteins - metabolism | Basal Nucleus of Meynert - metabolism | Nerve Degeneration - metabolism | Brain - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | Basal Nucleus of Meynert - drug effects | Neurons - metabolism | Cell Death - drug effects | bcl-2-Associated X Protein - genetics | Glycogen Synthase Kinase 3 - antagonists & inhibitors | Lithium - pharmacology | Brain - physiopathology | Gliosis - metabolism | Cells, Cultured | Enzyme Inhibitors - pharmacology | Intercellular Signaling Peptides and Proteins - genetics | bcl-2-Associated X Protein - metabolism | Rats | Glycogen Synthase Kinase 3 - metabolism | Rats, Sprague-Dawley | beta Catenin - metabolism | Hippocampus - metabolism | Animals | Cell Death - physiology | Intercellular Signaling Peptides and Proteins - pharmacology | Brain - pathology | Signal Transduction - physiology | Hippocampus - physiopathology | Proto-Oncogene Proteins c-bcl-2 - genetics | Synthesis | Glycogen | Cell death | Neurons | Analysis | Biochemistry | Alzheimer's disease | Index Medicus
Journal Article
Journal Article
ACS Medicinal Chemistry Letters, ISSN 1948-5875, 10/2013, Volume 4, Issue 10, pp. 979 - 984
Here, we describe the selection and optimization of a chemical series active in both a full-length and a fragment-based Huntington's disease (HD) assay.... 
phenotypic screening | 3-hydroxy-3-trifluoromethylpyrazoles | R6/2 mouse model | Huntington's disease | ADME | mutant Htt toxicity | CHEMISTRY, MEDICINAL | PROTEIN | GENE | phenotypic screening 3-hydroxy-3-trifluoromethylpyrazoles | DRUG DISCOVERY | DISEASE | DEATH | MODEL
Journal Article
Alzheimer's & Dementia, ISSN 1552-5260, 07/2006, Volume 2, Issue 3, p. S250
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2006, Volume 2, Issue 3, pp. S250 - S250
Journal Article
Journal Article
06/2019
The invention relates to a novel process for the preparation of rac-6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide (I) in pharmaceutically acceptable... 
METALLURGY | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS
Patent
10/2016
The invention relates to a novel process for the preparation of rac-6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide (I) in pharmaceutically acceptable... 
METALLURGY | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS
Patent
10/2016
Un procedimiento para la preparación del compuesto (I'-b) según el siguiente esquema:**Fórmula** en donde R es cadena de alquilo lineal, ramificado o cíclico,... 
METALLURGY | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS
Patent
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