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by Mack, Stephen C and Pajtler, Kristian W and Chavez, Lukas and Okonechnikov, Konstantin and Bertrand, Kelsey C and Wang, Xiuxing and Erkek, Serap and Federation, Alexander and Song, Anne and Lee, Christine and Wang, Xin and McDonald, Laura and Morrow, James J and Saiakhova, Alina and Sin-Chan, Patrick and Wu, Qiulian and Michaelraj, Kulandaimanuvel Antony and Miller, Tyler E and Hubert, Christopher G and Ryzhova, Marina and Garzia, Livia and Donovan, Laura and Dombrowski, Stephen and Factor, Daniel C and Luu, Betty and Valentim, Claudia L.L and Gimple, Ryan C and Morton, Andrew and Kim, Leo and Prager, Briana C and Lee, John J.Y and Wu, Xiaochong and Zuccaro, Jennifer and Thompson, Yuan and Holgado, Borja L and Reimand, Jüri and Ke, Susan Q and Tropper, Adam and Lai, Sisi and Vijayarajah, Senthuran and Doan, Sylvia and Mahadev, Vaidehi and Miñan, Ana Fernandez and Gröbner, Susanne N and Lienhard, Matthias and Zapatka, Marc and Huang, Zhiqin and Aldape, Kenneth D and Carcaboso, Angel M and Houghton, Peter J and Keir, Stephen T and Milde, Till and Witt, Hendrik and Li, Yan and Li, Chao-Jun and Bian, Xiu-Wu and Jones, David T.W and Scott, Ian and Singh, Sheila K and Huang, Annie and Dirks, Peter B and Bouffet, Eric and Bradner, James E and Ramaswamy, Vijay and Jabado, Nada and Rutka, James T and Northcott, Paul A and Lupien, Mathieu and Lichter, Peter and Korshunov, Andrey and Scacheri, Peter C and Pfister, Stefan M and Kool, Marcel and Taylor, Michael D and Rich, Jeremy N
Nature, ISSN 0028-0836, 01/2018, Volume 553, Issue 7686, pp. 101 - 105
Journal Article
Nature Genetics, ISSN 1061-4036, 01/2014, Volume 46, Issue 1, pp. 39 - 44
Journal Article
Nature Genetics, ISSN 1061-4036, 02/2015, Volume 47, Issue 3, pp. 257 - 262
Journal Article
by Thompson, Eric M, MD and Hielscher, Thomas, MSc and Bouffet, Eric, Prof and Remke, Marc, MD and Luu, Betty, BSc and Gururangan, Sridharan, Prof and McLendon, Roger E, Prof and Bigner, Darell D, Prof and Lipp, Eric S, MD and Perreault, Sebastien, MD and Cho, Yoon-Jae, MD and Grant, Gerald, MD and Kim, Seung-Ki, Prof and Lee, Ji Yeoun, MD and Rao, Amulya A Nageswara, MD and Giannini, Caterina, Prof and Li, Kay Ka Wai, MD and Ng, Ho-Keung, Prof and Yao, Yu, MD and Kumabe, Toshihiro, MD and Tominaga, Teiji, Prof and Grajkowska, Wieslawa A, Prof and Perek-Polnik, Marta, Prof and Low, David C Y, MBBCh and Seow, Wan Tew, MBBS and Chang, Kenneth T E, MBBCh and Mora, Jaume, Prof and Pollack, Ian F, Prof and Hamilton, Ronald L, MD and Leary, Sarah, MD and Moore, Andrew S, PhD and Ingram, Wendy J, PhD and Hallahan, Andrew R, MBBS and Jouvet, Anne, MD and Fèvre-Montange, Michelle, PhD and Vasiljevic, Alexandre, MD and Faure-Conter, Cecile, MD and Shofuda, Tomoko, PhD and Kagawa, Naoki, MD and Hashimoto, Naoya, MD and Jabado, Nada, MD and Weil, Alexander G, MD and Gayden, Tenzin, PhD and Wataya, Takafumi, MD and Shalaby, Tarek, MD and Grotzer, Michael, Prof and Zitterbart, Karel, PhD and Sterba, Jaroslav, Prof and Kren, Leos, MD and Hortobágyi, Tibor, Prof and Klekner, Almos, PhD and László, Bognár, Prof and Pócza, Tímea, MSc and Hauser, Peter, MD and Schüller, Ulrich, MD and Jung, Shin, Prof and Jang, Woo-Youl, MD and French, Pim J, Prof and Kros, Johan M, Prof and van Veelen, Marie-Lise C, MD and Massimi, Luca, MD and Leonard, Jeffrey R, Prof and Rubin, Joshua B, MD and Vibhakar, Rajeev, MD and Chambless, Lola B, MD and Cooper, Michael K, MD and Thompson, Reid C, Prof and Faria, Claudia C, MD and Carvalho, Alice, MD and Nunes, Sofia, MD and Pimentel, José, MD and Fan, Xing, MD and Muraszko, Karin M, Prof and López-Aguilar, Enrique, MD and Lyden, David, Prof and Garzia, Livia, PhD and Shih, David J H, PhD and Kijima, Noriyuki, MD and Schneider, Christian, MD and Adamski, Jennifer, PhD and Northcott, Paul A, PhD and Kool, Marcel, PhD and Jones, David T W, PhD and Chan, Jennifer A, MD and Nikolic, Ana, MD and Garre, Maria Luisa, MD and Van Meir, Erwin G, Prof and Osuka, Satoru, MD and Olson, Jeffrey J, Prof and Jahangiri, Arman, BSc and Castro, Brandyn A, BSc and Gupta, Nalin, MD and Weiss, William A, Prof and Moxon-Emre, Iska, MSc and Mabbott, Donald J, PhD and Lassaletta, Alvaro, MD and Hawkins, Cynthia E, Prof and Tabori, Uri, MD and Drake, James, Prof and Kulkarni, Abhaya, Prof and ...
The Lancet Oncology, ISSN 1470-2045, 2016, Volume 17, Issue 4, pp. 484 - 495
Journal Article
Nature Neuroscience, ISSN 1097-6256, 04/2019, Volume 22, Issue 4, pp. 507 - 508
The cell of origin for malignant brain tumors remains uncertain, but de-differentiation from mature cells in the CNS has always been considered a strong... 
Brain | Transformation | Neurons | Brain tumors | Glioblastoma | Solid wastes | Stem cells | Neural stem cells | Nervous system | Mutation | Tumors | Cancer
Journal Article
by Torchia, Jonathon, MSc and Picard, Daniel, MSc and Lafay-Cousin, Lucie, MD and Hawkins, Cynthia E, PhD and Kim, Seung-Ki, MD and Letourneau, Louis, BSc and Ra, Young-Shin, Prof and Ho, King Ching, MSc and Chan, Tiffany Sin Yu, PhD and Sin-Chan, Patrick, MSc and Dunham, Christopher P, MD and Yip, Stephen, FRCPC and Ng, Ho-keung, MD and Lu, Jian-Qiang, FRCPC and Albrecht, Steffen, MD and Pimentel, José, PhD and Chan, Jennifer A, MD and Somers, Gino R, MBBS and Zielenska, Maria, PhD and Faria, Claudia C, PhD and Roque, Lucia, PhD and Baskin, Berivan, PhD and Birks, Diane, MS and Foreman, Nick, Prof and Strother, Douglas, MD and Klekner, Almos, PhD and Garami, Miklos, PhD and Hauser, Peter, PhD and Hortobágyi, Tibor, PhD and Bognár, Laszló, PhD and Wilson, Beverly, MD and Hukin, Juliette, FRCPC and Carret, Anne-Sophie, MD and Van Meter, Timothy E, PhD and Nakamura, Hideo, MD and Toledano, Helen, MD and Fried, Iris, MD and Fults, Daniel, MD and Wataya, Takafumi, PhD and Fryer, Chris, FRCPC and Eisenstat, David D, MD and Scheineman, Katrin, Prof and Johnston, Donna, MD and Michaud, Jean, MD and Zelcer, Shayna, MD and Hammond, Robert, MD and Ramsay, David A, MBChB and Fleming, Adam J, MD and Lulla, Rishi R, MD and Fangusaro, Jason R, MD and Sirachainan, Nongnuch, MD and Larbcharoensub, Noppadol, MD and Hongeng, Suradej, MD and Barakzai, Muhammad Abrar, MD and Montpetit, Alexandre, PhD and Stephens, Derek, MSc and Grundy, Richard G, FRCPCH and Schüller, Ulrich, MD and Nicolaides, Theodore, MD and Tihan, Tarik, PhD and Phillips, Joanna, PhD and Taylor, Michael D, PhD and Rutka, James T, MD and Dirks, Peter, PhD and Bader, Gary D, PhD and Warmuth-Metz, Monika, Prof and Rutkowski, Stefan, Prof and Pietsch, Torsten, Prof and Judkins, Alexander R, MD and Jabado, Nada, PhD and Bouffet, Eric, Prof and Huang, Annie, Dr and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för immunologi, genetik och patologi and Uppsala universitet and Medicinsk genetik och genomik
Lancet Oncology, The, ISSN 1470-2045, 2015, Volume 16, Issue 5, pp. 569 - 582
Journal Article
by Morrissy, A. Sorana and Garzia, Livia and Shih, David J. H and Zuyderduyn, Scott and Huang, Xi and Skowron, Patryk and Remke, Marc and Cavalli, Florence M. G and Ramaswamy, Vijay and Lindsay, Patricia E and Jelveh, Salomeh and Donovan, Laura K and Wang, Xin and Luu, Betty and Zayne, Kory and Li, Yisu and Mayoh, Chelsea and Thiessen, Nina and Mercier, Eloi and Mungall, Karen L and Ma, Yusanne and Tse, Kane and Zeng, Thomas and Shumansky, Karey and Roth, Andrew J. L and Shah, Sohrab and Farooq, Hamza and Kijima, Noriyuki and Holgado, Borja L and Lee, John J. Y and Matan-Lithwick, Stuart and Liu, Jessica and Mack, Stephen C and Manno, Alex and Michealraj, K.A and Nor, Carolina and Peacock, John and Qin, Lei and Reimand, Juri and Rolider, Adi and Thompson, Yuan Y and Wu, Xiaochong and Pugh, Trevor and Ally, Adrian and Bilenky, Mikhail and Butterfield, Yaron S. N and Carlsen, Rebecca and Cheng, Young and Chuah, Eric and Corbett, Richard D and Dhalla, Noreen and He, An and Lee, Darlene and Li, Haiyan I and Long, William and Mayo, Michael and Plettner, Patrick and Qian, Jenny Q and Schein, Jacqueline E and Tam, Angela and Wong, Tina and Birol, Inanc and Zhao, Yongjun and Faria, Claudia C and Pimentel, José and Nunes, Sofia and Shalaby, Tarek and Grotzer, Michael and Pollack, Ian F and Hamilton, Ronald L and Li, Xiao-Nan and Bendel, Anne E and Fults, Daniel W and Walter, Andrew W and Kumabe, Toshihiro and Tominaga, Teiji and Collins, V. Peter and Cho, Yoon-Jae and Hoffman, Caitlin and Lyden, David and Wisoff, Jeffrey H and Garvin, James H and Stearns, Duncan S and Massimi, Luca and Schüller, Ulrich and Sterba, Jaroslav and Zitterbart, Karel and Puget, Stephanie and Ayrault, Olivier and Dunn, Sandra E and Tirapelli, Daniela P. C and Carlotti, Carlos G and Wheeler, Helen and Hallahan, Andrew R and Ingram, Wendy and MacDonald, Tobey J and Olson, Jeffrey J and Van Meir, Erwin G and Lee, Ji-Yeoun and Wang, Kyu-Chang and ...
Nature, ISSN 0028-0836, 01/2016, Volume 529, Issue 7586, pp. 351 - 357
The development of targeted anti-cancer therapies through the study of cancer genomes is intended to increase survival rates and decrease treatment-related... 
HETEROGENEITY | CANCER EVOLUTION | CELLS | IMPACT | MULTIDISCIPLINARY SCIENCES | SUBGROUP MEDULLOBLASTOMA | DYNAMICS | MUTATIONS | SEQUENCING DATA | LYMPHOBLASTIC-LEUKEMIA | GENOME | Clone Cells - drug effects | Humans | Male | Medulloblastoma - therapy | Radiotherapy, Image-Guided | Selection, Genetic - drug effects | Drosophila melanogaster - genetics | Neoplasm Recurrence, Local - pathology | Medulloblastoma - radiotherapy | DNA Mutational Analysis | Medulloblastoma - pathology | Female | Medulloblastoma - surgery | Cerebellar Neoplasms - pathology | Medulloblastoma - genetics | Molecular Targeted Therapy - methods | Disease Models, Animal | Signal Transduction | Neoplasm Recurrence, Local - therapy | Drosophila melanogaster - cytology | Cerebellar Neoplasms - genetics | Clone Cells - metabolism | Genome, Human - genetics | Xenograft Model Antitumor Assays | Animals | Clone Cells - pathology | Craniospinal Irradiation | Neoplasm Recurrence, Local - genetics | Mice | Cerebellar Neoplasms - therapy | Cerebellar Neoplasms - surgery | Cerebellar Neoplasms - radiotherapy | Clonal selection theory | Care and treatment | Medulloblastoma | Oncology, Experimental | Genetic aspects | Research | Cancer | Genes | Cloning | Clinical trials | Cytotoxicity | Genomes | Radiation therapy | Metastasis | Cancer therapies | Rodents | Medical prognosis | Mutation | Tumors | Index Medicus
Journal Article
by Northcott, Paul A and Shih, David J. H and Peacock, John and Garzia, Livia and Sorana Morrissy, A and Zichner, Thomas and Stútz, Adrian M and Korshunov, Andrey and Reimand, Júri and Schumacher, Steven E and Beroukhim, Rameen and Ellison, David W and Marshall, Christian R and Lionel, Anath C and MacK, Stephen and Dubuc, Adrian and Yao, Yuan and Ramaswamy, Vijay and Luu, Betty and Rolider, Adi and Cavalli, Florence M. G and Wang, Xin and Remke, Marc and Wu, Xiaochong and Chiu, Readman Y. B and Chu, Andy and Chuah, Eric and Corbett, Richard D and Hoad, Gemma R and Jackman, Shaun D and Li, Yisu and Lo, Allan and Mungall, Karen L and Ming Nip, Ka and Qian, Jenny Q and Raymond, Anthony G. J and Thiessen, Nina and Varhol, Richard J and Birol, Inanc and Moore, Richard A and Mungall, Andrew J and Holt, Robert and Kawauchi, Daisuke and Roussel, Martine F and Kool, Marcel and Jones, David T. W and Witt, Hendrick and Fernandez-L, Africa and Kenney, Anna M and Wechsler-Reya, Robert J and Dirks, Peter and Aviv, Tzvi and Grajkowska, Wieslawa A and Perek-Polnik, Marta and Haberler, Christine C and Delattre, Olivier and Reynaud, Stéphanie S and Doz, François F and Pernet-Fattet, Sarah S and Cho, Byung-Kyu and Kim, Seung-Ki and Wang, Kyu-Chang and Scheurlen, Wolfram and Eberhart, Charles G and Fèvre-Montange, Michelle and Jouvet, Anne and Pollack, Ian F and Fan, Xing and Muraszko, Karin M and Yancey Gillespie, G and Di Rocco, Concezio and Massimi, Luca and Michiels, Erna M. C and Kloosterhof, Nanne K and French, Pim J and Kros, Johan M and Olson, James M and Ellenbogen, Richard G and Zitterbart, Karel and Kren, Leos and Thompson, Reid C and Cooper, Michael K and Lach, Boleslaw and McLendon, Roger E and Bigner, Darell D and Fontebasso, Adam and Albrecht, Steffen and Jabado, Nada and Lindsey, Janet C and Bailey, Simon and Gupta, Nalin and Weiss, William A and Bognár, László and Klekner, Almos and Van Meter, Timothy E and Kumabe, Toshihiro and Tominaga, Teiji and Elbabaa, Samer K and Leonard, Jeffrey R and Rubin, Joshua B and ...
Nature, ISSN 0028-0836, 08/2012, Volume 487, Issue 7409, pp. 49 - 56
Journal Article