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Biochemical Journal, ISSN 0264-6021, 01/2019, Volume 476, Issue 2, pp. 375 - 384
HIV protease is essential for processing the Gag polyprotein to produce infectious virions and is a major target in antiretroviral therapy. We have identified... 
SITE MUTATIONS | IMPACT | VARIANTS | VIRAL FITNESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | REVERSE-TRANSCRIPTASE | IMMUNODEFICIENCY-VIRUS TYPE-1 | DRUG-RESISTANCE | DELETIONS | REGION
Journal Article
The Protein Journal, ISSN 1572-3887, 8/2018, Volume 37, Issue 4, pp. 311 - 323
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2014, Volume 289, Issue 46, pp. 32243 - 32252
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 10/2014, Volume 426, Issue 21, p. 3569
Many studies have characterized how changes to the stability and internal motions of a protein during activation can contribute to their catalytic function,... 
Hydrogen | Chemical properties | Catalysis
Journal Article
BIOCHEMISTRY, ISSN 0006-2960, 01/2014, Volume 53, Issue 1, pp. 57 - 67
Chloride intracellular channel protein 1 (CLIC1) is a dual-state protein that can exist either as a soluble monomer or in an integral membrane form. The... 
CIRCULAR-DICHROISM SPECTRA | MEMBRANE-INSERTION | SECONDARY-STRUCTURE | MOLECULAR-DYNAMICS | PEPTIDES | SIDE-CHAIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | HELIX-HELIX ASSOCIATION | ION CHANNELS | POLAR RESIDUES | OLIGOMERIZATION | Physiological aspects | Chloride channels | Research | Chemical properties | Membrane proteins
Journal Article
JOURNAL OF MOLECULAR BIOLOGY, ISSN 0022-2836, 10/2014, Volume 426, Issue 21, pp. 3569 - 3589
Many studies have characterized how changes to the stability and internal motions of a protein during activation can contribute to their catalytic function,... 
c-Jun N-terminal kinase | CATALYTIC SUBUNIT | CONFORMATIONAL MOBILITY | hydrogen exchange | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | protein dynamics | DEPENDENT PROTEIN-KINASE | MASS-SPECTROMETRY | IN-VITRO | ERK2 | MAP kinases | DEUTERIUM-EXCHANGE | DYNAMICS | mass spectrometry | REVEALS
Journal Article
Antiviral therapy, 04/2019
Protease inhibitors form the main component of second-line antiretroviral treatment in South Africa. Despite their efficacy, mutations arising within the HIV-1... 
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 03/2013, Volume 432, Issue 4, p. 683
Journal Article
The Biochemical journal, 12/2018
HIV protease is essential for processing the Gag polyprotein to produce infectious virions and is a major target in antiretroviral therapy. We have identified... 
Journal Article
Inorganic Chemistry Communications, ISSN 1387-7003, 07/2015, Volume 57, p. 15
The kinetics of the substitution of H.sub.2O on Co(III) in aquacobalamin (H.sub.2OCbl.sup.+, vitamin B.sub.12a) and in a Co(III) corrole analogue of B.sub.12a,... 
Cobalt | Vitamins
Journal Article
Inorganic Chemistry Communications, ISSN 1387-7003, 07/2015, Volume 57, pp. 15 - 17
The kinetics of the substitution of H 2 O on Co(III) in aquacobalamin (H 2 OCbl + , vitamin B 12a ) and in a Co(III) corrole analogue of B 12a ,... 
Cobalt corrole | Ligand substitution reactions | Vitamin B 12a | Aquacobalamin | Co(III)
Journal Article
Protein Expression and Purification, ISSN 1046-5928, 02/2013, Volume 87, Issue 2, p. 87
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Codon | Phosphotransferases
Journal Article
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