X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (201) 201
animals (165) 165
biochemistry (116) 116
biochemistry & molecular biology (110) 110
chemistry (107) 107
apoptosis (106) 106
metallurgy (106) 106
microbiology (104) 104
culture media (103) 103
mice (102) 102
enzymology (100) 100
beer (99) 99
compositions thereof (99) 99
microorganisms or enzymes (99) 99
mutation or genetic engineering (99) 99
propagating, preserving or maintaining microorganisms (99) 99
spirits (99) 99
vinegar (99) 99
wine (99) 99
peptides (90) 90
organic chemistry (89) 89
human necessities (74) 74
hygiene (74) 74
medical or veterinary science (74) 74
preparations for medical, dental, or toilet purposes (74) 74
cell biology (73) 73
molecular sequence data (69) 69
amino acid sequence (68) 68
cell line (61) 61
multidisciplinary sciences (60) 60
proteins (60) 60
research (54) 54
signal transduction (52) 52
compositions or test papers therefor (47) 47
condition-responsive control in microbiological orenzymological processes (47) 47
measuring or testing processes involving enzymes, nucleicacids or microorganisms (47) 47
processes of preparing such compositions (47) 47
fermentation or enzyme-using processes to synthesise a desiredchemical compound or composition or to separate optical isomersfrom a racemic mixture (45) 45
physiological aspects (45) 45
activation (43) 43
cell death (43) 43
immunology (40) 40
thrombospondins (39) 39
cells, cultured (36) 36
mutation (36) 36
caspases (35) 35
protein (35) 35
sugars (35) 35
cell-death (34) 34
derivatives thereof (34) 34
nucleic acids (34) 34
nucleosides (34) 34
nucleotides (34) 34
nf-kappa b - metabolism (33) 33
transfection (33) 33
investigating or analysing materials by determining theirchemical or physical properties (32) 32
measuring (32) 32
physics (32) 32
specific therapeutic activity of chemical compounds ormedicinal preparations (32) 32
testing (32) 32
tumor cells, cultured (32) 32
cysteine endopeptidases - metabolism (31) 31
gene (31) 31
cloning, molecular (30) 30
female (30) 30
protein binding (30) 30
phosphorylation (29) 29
proteins - metabolism (29) 29
sequence homology, amino acid (28) 28
enzyme activation (26) 26
carrier proteins - metabolism (25) 25
mice, inbred c57bl (25) 25
nf-kappa-b (25) 25
ubiquitination (25) 25
apoptosis - physiology (24) 24
inflammation (24) 24
ubiquitin (24) 24
ubiquitin - metabolism (24) 24
cells (23) 23
ligands (23) 23
adaptor proteins, signal transducing (22) 22
base sequence (22) 22
male (22) 22
caspase 9 (20) 20
cytokines (20) 20
expression (20) 20
molecular biology (20) 20
protein structure, tertiary (20) 20
cancer (18) 18
caspase 1 - metabolism (18) 18
caspases - metabolism (18) 18
mice, knockout (18) 18
receptors (18) 18
tumor necrosis factor-alpha - pharmacology (18) 18
antibodies (17) 17
binding sites (17) 17
enzymes (17) 17
receptor (17) 17
receptors, tumor necrosis factor - metabolism (17) 17
encodes (16) 16
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (561) 561
French (42) 42
German (19) 19
Danish (2) 2
Japanese (2) 2
Portuguese (2) 2
Spanish (2) 2
Chinese (1) 1
Korean (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Trends in Pharmacological Sciences, ISSN 0165-6147, 2013, Volume 34, Issue 11, pp. 596 - 598
...Vishva M. Dixit is the Vice President of Early Discovery Research at Genentech, where he has spent his career characterizing mechanisms of cell death... 
Advanced Basic Science | PHARMACOLOGY & PHARMACY | Cell Death - physiology | History, 21st Century | Cell Biology - history | Humans
Journal Article
Cell death and differentiation, ISSN 1350-9047, 2019, Volume 26, Issue 4, pp. 597 - 604
Vishva M. Dixit, M.D., Vice President of Physiological Chemistry at Genentech, Inc... 
DOMAIN-CONTAINING RECEPTOR | DEATH DOMAIN | ACTIVATION | PROTEIN | CLEAVES | BIOCHEMISTRY & MOLECULAR BIOLOGY | MAMMALIAN HOMOLOG | FAS | IDENTIFICATION | FAMILY | MEMBER | CELL BIOLOGY | Apoptosis | Q and A
Journal Article
Nature reviews. Molecular cell biology, ISSN 1471-0080, 2011, Volume 12, Issue 7, pp. 439 - 452
Journal Article
Cell research, ISSN 1001-0602, 2016, Volume 26, Issue 4, pp. 484 - 498
...’,DepaltmentofDiscoveo’Oncology,Genentech,Inc., DNA Sotf,}SanFrancisco,CA94080,USA;DepaltmentofPhysio—logicalChemis'tly.Genentech,hw.,,DNA 0South SanFrancisco,CA 94080.USADynam ic m... 
动态调制 | 药物靶点 | 药物开发 | 蛋白质水平 | 美国食品 | 蛋白质降解 | 泛素-蛋白酶体系统 | 哺乳动物细胞 | hydrophobic tag | SERD | ubiquitin-proteasome system | PROTAC | degrader | drug target | Ubiquitination - drug effects | Proteasome Endopeptidase Complex - metabolism | Proteasome Inhibitors | Drug Discovery | Ubiquitin - metabolism | Review
Journal Article
The Journal of cell biology, ISSN 1540-8140, 2009, Volume 187, Issue 1, pp. 61 - 70
Inflammasomes activate caspase-1 for processing and secretion of the cytokines interleukin-lβ (IL-1β) and IL-18. Cryopyrin/NALP3/NLRP3 is an essential... 
ATP binding cassette transporters | Receptors | Monocytes | Cytokines | Secretion | Adenosine triphosphatases | Antibodies | Reports | Macrophages | Cell extracts | Vehicles | BINDING CASSETTE TRANSPORTER | CASPASE-1 | P2X RECEPTOR | INSULIN-SECRETION | MOUSE | ATP BINDING | INTERLEUKIN-1-BETA RELEASE | COLD AUTOINFLAMMATORY SYNDROME | SULFONYLUREA RECEPTOR | NALP3 INFLAMMASOME | CELL BIOLOGY | Hypoglycemic Agents - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Lipopolysaccharides - metabolism | Caspase 1 - metabolism | Male | Monocytes - metabolism | Caspase 1 - immunology | Monocytes - immunology | Adenosine Triphosphatases - immunology | Lipopolysaccharides - immunology | Adenosine Triphosphate - pharmacology | Inflammation - metabolism | Glyburide - pharmacology | Salmonella typhimurium - classification | Macrophages - immunology | Interleukin-1beta - secretion | Salmonella typhimurium - physiology | Salmonella typhimurium - genetics | Salmonella typhimurium - immunology | Mice, Inbred C57BL | Carrier Proteins - antagonists & inhibitors | Cells, Cultured | Adenosine Triphosphatases - metabolism | Glyburide - chemistry | Hypoglycemic Agents - chemistry | Inflammation - immunology | Glyburide - metabolism | Random Allocation | Enzyme Activation - drug effects | Hypoglycemic Agents - pharmacology | Mice, Knockout | Carrier Proteins - genetics | Macrophages - metabolism | Animals | Glyburide - immunology | Lipopolysaccharides - pharmacology | Interleukin-18 - secretion | Mice | Mice, Inbred BALB C | Mutation | Inflammation - enzymology | Hypoglycemic Agents - immunology | Physiological aspects | Cellular proteins | Interleukin-1 | Research | Glibenclamide | Health aspects
Journal Article
Nature reviews. Immunology, ISSN 1474-1741, 2016, Volume 16, Issue 7, pp. 407 - 420
Inflammasomes are multiprotein signalling platforms that control the inflammatory response and coordinate antimicrobial host defences. They are assembled by... 
AIM2 INFLAMMASOME | DNA SENSOR | INNATE IMMUNE RECOGNITION | III SECRETION APPARATUS | NLRC4 INFLAMMASOME | CYTOPLASMIC LPS | HOST-DEFENSE | MELANOMA 2 | NLRP3 INFLAMMASOME | IMMUNOLOGY | CELL-DEATH | Inflammasomes - physiology | Signal Transduction - immunology | Animals | Humans | Cell death | Research
Journal Article