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Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 12/2018, Volume 61, Issue 24, pp. 11384 - 11397
The discovery of D1 subtype-selective agonists with drug-like properties has been an enduring challenge for the greater part of 40 years. All known... 
Journal Article
Journal Article
Behavioural Brain Research, ISSN 0166-4328, 09/2013, Volume 252, pp. 405 - 414
Social withdrawal is one of several negative symptoms of schizophrenia, all of which are poorly treated by current therapies. One challenge in developing... 
GABA | d-Cycloserine | Mouse | NMDA receptor | Negative symptom | Social approach | D-Cycloserine | AUTISM | RECEPTOR | PHENOTYPES | NEUROSCIENCES | GLUTAMATE | HYPOFUNCTION | HYPOTHESIS | ANIMAL-MODELS | BEHAVIORAL SCIENCES | MICE | Schizophrenia | Methyl aspartate | Dextroamphetamine | Analysis
Journal Article
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, ISSN 0960-894X, 01/2016, Volume 26, Issue 2, pp. 650 - 655
Selective activation of the M-1 receptor via a positive allosteric modulator (PAM) is a new approach for the treatment of the cognitive impairments associated... 
ACTIVATION | CHEMISTRY, MEDICINAL | SERIES | ALZHEIMERS-DISEASE | CHEMISTRY, ORGANIC | SCHIZOPHRENIA | XANOMELINE | Azaindole amide | AGONISTS | DISCOVERY | M-1 selective activator | MUSCARINIC ACETYLCHOLINE-RECEPTOR | M-1 positive allosteric modulator (PAM) | Intra-molecular hydrogen bond (IMHB) | IN-VIVO | CENTRAL-NERVOUS-SYSTEM
Journal Article
ACS Chemical Neuroscience, ISSN 1948-7193, 01/2017, Volume 8, Issue 1, pp. 165 - 177
Journal Article
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