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NATURE CHEMICAL BIOLOGY, ISSN 1552-4450, 06/2012, Volume 8, Issue 6, pp. 576 - 582
We devised a high-throughput chemoproteomics method that enabled multiplexed screening of 16,000 compounds against native protein and lipid kinases in cell... 
RHEUMATOID-ARTHRITIS | PI3K | CLASS-IB | INSULIN-RESISTANCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | INDUCED INFLAMMATION | KEY ROLE | KINASE INHIBITORS | JOINT INFLAMMATION | CHEMOPROTEOMICS | IDENTIFICATION | Small Molecule Libraries - pharmacology | Arthritis, Experimental - drug therapy | Rats, Wistar | Humans | Interleukin-17 - immunology | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Male | Structure-Activity Relationship | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Arthritis, Experimental - pathology | T-Lymphocytes, Helper-Inducer - drug effects | Enzyme Inhibitors - pharmacokinetics | T-Lymphocytes, Helper-Inducer - immunology | Enzyme Inhibitors - chemistry | T-Lymphocytes, Helper-Inducer - enzymology | T-Lymphocytes, Helper-Inducer - cytology | Mice, Inbred DBA | Molecular Structure | Binding, Competitive | Cell Line | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Small Molecule Libraries - therapeutic use | Rats | Arthritis, Experimental - immunology | Drug Discovery | Enzyme Inhibitors - therapeutic use | Cell Movement - drug effects | Small Molecule Libraries - chemistry | Animals | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Cell Differentiation - drug effects | Anti-Inflammatory Agents, Non-Steroidal - pharmacokinetics | Mice | Class Ib Phosphatidylinositol 3-Kinase - antagonists & inhibitors | Small Molecule Libraries - pharmacokinetics | Index Medicus
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 06/2012, Volume 8, Issue 6, p. 576
  We devised a high-throughput chemoproteomics method that enabled multiplexed screening of 16,000 compounds against native protein and lipid kinases in cell... 
Journal Article
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