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science & technology (18) 18
animals (17) 17
mice (16) 16
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female (8) 8
male (8) 8
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1. Full Text Juno is the egg Izumo receptor and is essential for mammalian fertilization
by Bianchi, Enrica and Doe, Brendan and Goulding, David and Wright, Gavin J
Nature (London), ISSN 0028-0836, 2014, Volume 508, Issue 7497, pp. 483 - 487
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Humans | Male | Spermatozoa - metabolism | Infertility, Female - genetics | Immunoglobulins - metabolism | Oocytes - cytology | Fertility - genetics | Fertilization - physiology | Time Factors | Conserved Sequence | Female | Membrane Proteins - metabolism | Parthenogenesis | Oocytes - metabolism | Fertilization - genetics | Receptors, Cell Surface - metabolism | Mammals | Genes, Essential | Ovum - cytology | Sperm Injections, Intracytoplasmic | Animals | Glycosylphosphatidylinositols - metabolism | Receptors, Cell Surface - deficiency | Mice | Evolution, Molecular | Ovum - metabolism | Receptors, Cell Surface - genetics | Research | Sexual reproduction | Health aspects | Folic acid | Proteins | In vitro fertilization | Fertility | Sperm | Cloning | Females | Binding sites | Eggs | Index Medicus
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2. Full Text Revealing hidden complexities of genomic rearrangements generated with Cas9
by Boroviak, Katharina and Fu, Beiyuan and Yang, Fengtang and Doe, Brendan and Bradley, Allan
Scientific reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 12867 - 8
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | CRISPR | Zygotes | Chromosomes | Base pairs
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3. Full Text Author Correction: Revealing hidden complexities of genomic rearrangements generated with Cas9 (Scientific Reports DOI: 10.1038/s41598-017-12740-6)
by Boroviak, Katharina and Fu, Beiyuan and Yang, Fengtang and Doe, Brendan and Bradley, Allan
Scientific reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 5765 - 1
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4. Full Text Derivation and maintenance of mouse haploid embryonic stem cells
by Elling, Ulrich and Woods, Michael and Forment, Josep and Fu, Beiyuan and Yang, Fengtang and Ng, Bee Ling and Vicente, Jose R and Adams, David J and Doe, Brendan and Jackson, Stephen P and Penninger, Josef M and Balmus, Gabriel
Nature protocols, ISSN 1754-2189, 07/2019, Volume 14, Issue 7, pp. 1991 - 2014
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Biochemical Research Methods | Science & Technology | Cell Line | Mouse Embryonic Stem Cells - physiology | Mice, Inbred C57BL | Blastocyst - cytology | Mouse Embryonic Stem Cells - cytology | Workflow | Cell Separation - methods | Mice, Inbred Strains | Cell Culture Techniques - methods | Haploidy | Animals | Female | Mice | Genetic research | Genetic aspects | Observations | Growth | Stem cells | Gametes | Ploidy | Genes | Embryo cells | Stem cell transplantation | Derivation | Genomes | Embryos | Genetic screening | Mammalian cells | Mutagenesis | Cell lines | Mutation | Chromosomes | Index Medicus | haploid stem cell | genetic screen | Haplobank | haploid ESC
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5. Full Text High-throughput discovery of novel developmental phenotypes
by Dickinson, Mary E and Ji, Xiao and Teboul, Lydia and Wong, Michael D and White, Jacqueline K and Meehan, Terrence F and Westerberg, Henrik and Adissu, Hibret and Baker, Candice N and Brianna Caddle, L and Chiani, Francesco and Clary, Dave and Cleak, James and Daly, Mark J and Denegre, James M and Edie, Sarah M and Gailus-Durner, Valerie and Galli, Antonella and Gambadoro, Alessia and Gallegos, Juan and Johnson, Sara J and Lawson, Thomas N and Lek, Monkol and Mason, Jeremy and McElwee, Melissa L and Nutter, Lauryl M.J and Rowland, Douglas J and Samocha, Kaitlin E and Seavitt, John R and Szoke-Kovacs, Zsombor and Trainor, Amanda G and Wakana, Shigeharu and Warren, Jonathan and West, David B and Tocchini-Valentini, Glauco P and Flicek, Paul and Bradley, Allan and Skarnes, William C and Justice, Monica J and Parkinson, Helen E and Moore, Mark and Wells, Sara and Svenson, Karen L and Herault, Yann and Mallon, Ann-Marie and Mark Henkelman, R and Brown, Steve D.M and Adams, David J and Kent Lloyd, K.C and McKerlie, Colin and Urban, Barbara and Lund, Caroline and LaCasse, Taylor and Mehalow, Adrienne and Taft, Robert and Kutney, Peter and Goodwin, Leslie and Kales, Susan and Urban, Rachel and Palmer, Kristina and Pertuy, Fabien and Bitz, Deborah and Weber, Bruno and Jacobs, Hughes and Ennah, Hamid and Ali-Hadji, Dalila and Wattenhofer-Donze, Marie and André, Philippe and Birling, Marie-Christine and Pavlovic, Guillaume and Sorg, Tania and Morse, Iva and Benso, Frank and Harrison, Jackie and Guo, Ruolin and Qu, Dawei and Spring, Shoshana and Ellegood, Jacob and Shang, Xueyuan and Feugas, Pat and Creighton, Amie and Penton, Patricia Castellanos and Danisment, Ozge and Griggs, Nicola and Tudor, Catherine L and Green, Angela L and Icoresi Mazzeo, Cecilia and Siragher, Emma and Lillistone, Charlotte and Gleeson, Diane and Sethi, Debarati and Bayzetinova, Tanya and Burvill, Jonathan and Habib, Bishoy and Maswood, Ryea and Woods, Michael and Grau, Evelyn and Sinclair, Caroline and Brown, Ellen and Ayabe, Shinya and Int Mouse Phenotyping Consortium and The International Mouse Phenotyping Consortium
Nature (London), ISSN 0028-0836, 09/2016, Volume 537, Issue 7621, pp. 508 - 514
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Genetic research | Phenotype | Research | High-throughput screening (Biochemical assaying) | Methods | Genotype & phenotype | Disease | Developmental biology | Genes | Genomes | Mutation | Embryos | Index Medicus | knockout | embryonic lethal | mouse | KOMP | IMPC | EUCOMM
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6. Full Text No unexpected CRISPR-Cas9 off-target activity revealed by trio sequencing of gene-edited mice
by Iyer, Vivek and Boroviak, Katharina and Thomas, Mark and Doe, Brendan and Riva, Laura and Ryder, Edward and Adams, David J
PLoS genetics, ISSN 1553-7390, 07/2018, Volume 14, Issue 7, pp. e1007503 - e1007503
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | RNA, Guide - genetics | Hair Color - genetics | Mice, Inbred C57BL | Genome - genetics | Mutagenesis - genetics | Male | Mice, Transgenic | Whole Genome Sequencing - methods | DNA Mutational Analysis - methods | CRISPR-Cas Systems - genetics | Animals | Pedigree | Female | Biological Variation, Population - genetics | Gene Editing - methods | Mice | Monophenol Monooxygenase - genetics | Research Design | Genetic engineering | Nucleotide sequencing | Methods | DNA sequencing | CRISPR | Parameter estimation | Mutagenesis | Laboratories | Software | Genomes | Mutation | Embryos | Bioinformatics | Deoxyribonucleic acid--DNA | Index Medicus | Deoxyribonucleic acid | DNA
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7. Full Text Genomic DNA Damage in Mouse Transgenesis
by Yasuhiro Yamauchi and Brendan Doe and Anna Ajduk and Monika A Ward
Biology of reproduction, ISSN 0006-3363, 11/2007, Volume 77, Issue 5, pp. 803 - 812
In vitro fertilization | Gamete biology | Embryo | Assisted reproductive technology | Sperm | Life Sciences & Biomedicine | Reproductive Biology | Science & Technology | Gynecology. Andrology. Obstetrics | Birth control | Biological and medical sciences | Medical sciences | Sterility. Assisted procreation | Gene Transfer Techniques | Oocytes - metabolism | Spermatozoa - transplantation | Embryonic Development - genetics | Genome - genetics | Chromatin Assembly and Disassembly | Mice, Transgenic - genetics | Male | Spermatozoa - metabolism | Cell Nucleus - ultrastructure | Comet Assay | Chromosomes - ultrastructure | Oocytes - cytology | Sperm Injections, Intracytoplasmic | Animals | Zygote - ultrastructure | Female | Mice | DNA Damage | Spermatozoa - ultrastructure | Chromosome Breakage | Index Medicus
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8. Full Text Generating CRISPR/Cas9-Derived Mutant Mice by Zygote Cytoplasmic Injection Using an Automatic Microinjector
by Doe, Brendan and Brown, Ellen and Boroviak, Katharina
Methods and protocols, ISSN 2409-9279, 01/2018, Volume 1, Issue 1, p. 5
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9. Full Text Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics
by Selloum, Mohammed and White, Jacqueline K and Morgan, Hugh and Sorg, Tania and Fray, Martin and Adler, Thure and Aguilar-Pimentel, Antonio and Amann, Gregory and André, Philippe and Atkins, Sarah and Ayadi, Abdel and Becker, Lore and Bedu, Elodie and Bekeredjian, Raffi and Birling, Marie-Christine and Bottomley, Joanna and Cater, Heather and Champy, Marie-France and Charles, Philippe and Chiani, Francesco and Codner, Gemma F and Combe, Roy and Dalloneau, Emilie and Dierich, André and Eickelberg, Oliver and Fertak, Lahcen El and Feigel, Tanja and Favor, Jack and Flenniken, Ann and Gambadoro, Alessia and Garrett, Lilian and Gates, Hilary and Gerdin, Anna-Karin and Gkoutos, George and Glasl, Lisa and Goetz, Patrice and Da Cruz, Isabelle Goncalves and Graw, Jochen and Hans, Wolfgang and Hicks, Geoff and Höfler, Heinz and Hoehndorf, Robert and Hough, Tertius and Houghton, Richard and Jacobs, Hughes and Jacquot, Sylvie and Jones, Nora and Katus, Hugo A and Kitchen, Sharon and Klingenspor, Martin and Klopstock, Thomas and Lalanne, Valerie and Le Marchand, Elise and Ludwig, Tonia and Maier, Holger and Mandel, Jean-Louis and Mark, Manuel and Meziane, Hamid and Micklich, Kateryna and Mittelhauser, Christophe and Moulaert, David and Muller, Stéphanie and Naton, Beatrix and Nutter, Lauryl M.J and Pellegata, Natalia S and Peter, Emilie and Petit-Demoulière, Benoit and Pickard, Amanda and Podrini, Christine and Potter, Paul and Puk, Oliver and Quintanilla-Fend, Leticia and Quwailid, Mohamed M and Riet, Fabrice and Roux, Michel and Rozman, Jan and Salisbury, Jennifer and Schiller, Evelyn and Schrewe, Anja and Simon, Michelle and Stöger, Claudia and Stöger, Tobias and Sun, Minxuan and Sunter, David and Teboul, Lydia and Tost, Monica and Vasseur, Laurent and Velot, Emilie and Vogt-Weisenhorn, Daniela and Wattenhofer-Donze, Marie and Wendling, Olivia and Westerberg, Henrik and Wolter, Anne and Wood, Joe and Yildirim, Ali Önder and Zimmer, Andreas and Steel, Karen P and Gailus-Durner, Valérie and Mallon, Ann-Marie and Brown, Steve D.M and EUMODIC Consortium
Nature genetics, ISSN 1061-4036, 08/2015, Volume 47, Issue 9, pp. 969 - 978
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Homozygote | Phenotype | Animals | Genetic Association Studies | Humans | Mice, Inbred C57BL | Molecular Sequence Annotation | Female | Heterozygote | Male | Mutation | Mice, Knockout | Research | Gene mutations | Human genome | Identification and classification | Health aspects | Consortia | Genotype & phenotype | Physiology | Genomes | Metabolism | Power | Index Medicus
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10. Full Text The mammalian gene function resource: The International Knockout Mouse Consortium
by Bradley, Allan and Anastassiadis, Konstantinos and Ayadi, Abdelkader and Battey, James and Bell, Cindy and Birling, Marie-Christine and Bottomley, Joanna and Brown, Steve and Bürger, Friederike and Bult, Carol and Bushell, Wendy and Collins, Francis and Desaintes, Christian and Doe, Brendan and Aris, Economides and Eppig, Janan and Finnell, Richard and Fletcher, Colin and Fray, Martin and Frendewey, David and Friedel, Roland and Grosveld, Frank and Hansen, J and Hérault, Yann and Hicks, Geoffrey and Hörlein, Aneas and Houghton, Catherine and Hrabé De Angelis, Martin and Huylebroeck, Danny and Iyer, Vivek and Jong, Pieter and Kadin, James and Kaloff, Cornelia and Kennedy, Karen and Koutsourakis, Manousos and Kent Lloyd, K.C and Marschall, Susan and Mason, Jeremy and McKerlie, Colin and McLeod, Michael and Melchner, Harald and Moore, Matt and Mujica, Alejano and Nagy, Anas and Nefedov, Mikhail and Nutter, Lauryl and Pavlovic, Guillaume and Peterson, Jane and Pollock, I and Ramirez-Solis, Ramiro and Rancourt, Derrick and Raspa, Marcello and Remacle, Jacques and Ringwald, Martin and Rosen, Barry and Rosenthal, Nadia and Rossant, Janet and Ruiz Noppinger, Patricia and Ryder, Steve and Schick, Joel Zupicich and Schnütgen, Frank and Schofield, Christopher and Seisenberger, Claudia and Selloum, Mohammed and Simpson, Elizabeth and Skarnes, William and Smedley, Damian and Stanford, William and Stewart, Francis and Stone, Kevin and Swan, Kate and Tadepally, Hamsa and Teboul, Jean Louis and Tocchini-Valentini, Glauco and Valenzuela, David and West, Anthony and Yamamura, Ken-Ichi and Yoshinaga, Yuko and Wurst, Martin
Mammalian genome, ISSN 0938-8990, 10/2012, Volume 23, Issue 9-10, pp. 580 - 586
Life Sciences | Anatomy | Zoology | Cell Biology | Biochemistry & Molecular Biology | Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Mice, Knockout - genetics | Mice | Animals | Internet | Internationality | Index Medicus
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11. Full Text Synthetic lethality between PAXX and XLF in mammalian development
by Balmus, Gabriel and Barros, Ana C and Wijnhoven, Paul W. G and Lescale, Chloé and Hasse, Hélène Lenden and Boroviak, Katharina and le Sage, Carlos and Doe, Brendan and Speak, Anneliese O and Galli, Antonella and Jacobsen, Matt and Deriano, Ludovic and Adams, David J and Blackford, Andrew N and Jackson, Stephen P
Genes & development, ISSN 0890-9369, 10/2016, Volume 30, Issue 19, pp. 2152 - 2157
Development | ATM | XLF | NHEJ | Synthetic lethality | PAXX | Genetics & Heredity | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cell Biology | Protein Kinases - metabolism | Synthetic Lethal Mutations - genetics | Protein Kinases - genetics | Mice, Inbred C57BL | Embryonic Development - genetics | Radiation Tolerance - genetics | Apoptosis - genetics | DNA-Binding Proteins - genetics | Mice, Knockout | DNA-Binding Proteins - metabolism | Animals | Trisaccharides - genetics | Epistasis, Genetic | Mice | Trisaccharides - metabolism | Genomic Instability - genetics | Embryonic development | DNA repair | Research | Index Medicus | Life Sciences | Immunology | Molecular biology | Biochemistry, Molecular Biology | Adaptive immunology | Cancer | development | Research Communication | synthetic lethality
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12. Full Text Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome
by Balmus, Gabriel and Larrieu, Delphine and Barros, Ana C and Collins, Casey and Abrudan, Monica and Demir, Mukerrem and Geisler, Nicola J and Lelliott, Christopher J and White, Jacqueline K and Karp, Natasha A and Atkinson, James and Kirton, Andrea and Jacobsen, Matt and Clift, Dean and Rodriguez, Raphael and Shannon, Carl and Sanderson, Mark and Gates, Amy and Dench, Joshua and Vancollie, Valerie and McCarthy, Catherine and Pearson, Selina and Cambridge, Emma and Isherwood, Christopher and Wilson, Heather and Grau, Evelyn and