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1. Full Text Cross-talk between Epstein-Barr virus and microenvironment in the pathogenesis of lymphomas
by Dolcetti, Riccardo
Seminars in Cancer Biology, ISSN 1044-579X, 2015, Volume 34, pp. 58 - 69
Abstract Epstein-Bar virus (EBV) is known to directly drive the neoplastic transformation of lymphoid cells resulting in the development of a variety of... 
Hematology, Oncology and Palliative Medicine | Epstein-Barr virus | Immune response | Microenvironment | Exosome | Lymphoma | NASOPHARYNGEAL CARCINOMA-CELLS | ONCOLOGY | BURKITTS-LYMPHOMA | MEMBRANE-PROTEIN 1 | PLASMODIUM-FALCIPARUM | REGULATORY T-CELLS | HODGKIN LYMPHOMA | LATENT MEMBRANE-PROTEIN-1 | NF-KAPPA-B | POSTTRANSPLANT LYMPHOPROLIFERATIVE DISEASE | UP-REGULATION | Exosomes - metabolism | Epstein-Barr Virus Infections - virology | Signal Transduction | Immunomodulation | Herpesvirus 4, Human - physiology | Humans | Stromal Cells - metabolism | Cell Communication | Tumor Microenvironment | Bystander Effect | Neovascularization, Pathologic - etiology | Lymphoma - metabolism | Animals | B-Lymphocytes - immunology | Lymphoma - etiology | Stromal Cells - virology | B-Lymphocytes - virology | Biomarkers | Epstein-Barr Virus Infections - complications | Lymphoma - pathology | Neovascularization, Pathologic - metabolism | B-Lymphocytes - metabolism | Cell Transformation, Viral | Lymphomas | B cells
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2. 157 Pathogenesis of Epstein-Barr Virus-driven lymphomas of HIV+ patients: new insights of potential clinical relevance
by Dolcetti, Riccardo
JAIDS Journal of Acquired Immune Deficiency Syndromes, ISSN 1525-4135, 04/2014, Volume 65, pp. 1 - 1
Human Immunodeficiency Virus (HIV)+ patients have an increased risk to develop lymphomas, including a significant fraction of histotypes associated with... 
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3. Full Text 157 Pathogenesis of Epstein-Barr Virus-driven lymphomas of HIV+ patients
: new insights of potential clinical relevance
by Dolcetti, Riccardo
JAIDS Journal of Acquired Immune Deficiency Syndromes, ISSN 1525-4135, 04/2014, Volume 65, Issue Suppl 2, pp. 67 - 67
Human Immunodeficiency Virus (HIV)+ patients have an increased risk to develop lymphomas, including a significant fraction of histotypes associated with... 
Abstract
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4. 157 Pathogenesis of Epstein-Barr Virus-driven lymphomas of HIV+ patients: new insights of potential clinical relevance
by Riccardo Dolcetti
Journal of Acquired Immune Deficiency Syndromes, ISSN 1525-4135, 04/2014, Volume 65, p. 1
  Human Immunodeficiency Virus (HIV)+ patients have an increased risk to develop lymphomas, including a significant fraction of histotypes associated with... 
Antiretroviral drugs | Immunology | Human immunodeficiency virus--HIV | Lymphomas | T cell receptors | Viral infections | Virology
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5. Full Text The interplay between Epstein-Barr virus and the immune system: a rationale for adoptive cell therapy of EBV-related disorders
by Anna Merlo and Riccardo Turrini and Riccardo Dolcetti and Debora Martorelli and Elena Muraro and Patrizia Comoli and Antonio Rosato
Haematologica, ISSN 0390-6078, 10/2010, Volume 95, Issue 10, pp. 1769 - 1777
The Epstein-Barr virus has evolved a plethora of strategies to evade immune system recognition and to establish latent infection in memory B cells, where the... 
SOLID-ORGAN TRANSPLANTATION | METASTATIC MELANOMA | NASOPHARYNGEAL CARCINOMA | BONE-MARROW-TRANSPLANTATION | NUCLEAR ANTIGEN 1 | COMPLEX CLASS-I | POSITIVE HODGKINS-DISEASE | IN-VIVO EXPANSION | HEMATOLOGY | POSTTRANSPLANT LYMPHOPROLIFERATIVE DISEASE | CYTOTOXIC T-LYMPHOCYTES | Hematologic Neoplasms - therapy | Immunotherapy, Adoptive | Hematologic Neoplasms - virology | Humans | Herpesvirus 4, Human - immunology | Epstein-Barr Virus Infections - complications | Immune Evasion - immunology | Review
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6. Full Text B lymphocytes and Epstein–Barr virus: The lesson of post-transplant lymphoproliferative disorders
by Dolcetti, Riccardo
Autoimmunity Reviews, ISSN 1568-9972, 2007, Volume 7, Issue 2, pp. 96 - 101
Abstract Epstein–Barr virus (EBV) is a ubiquitous human γ-herpes virus that establishes a life-long asymptomatic infection in immunocompetent hosts by... 
Allergy and Immunology | Post-transplantation lymphoproliferative disorders | B lymphocytes | Viral load | Epstein–Barr virus | Epstein-Barr virus | LYTIC INFECTION | DNA LOAD | PERIPHERAL-BLOOD | IMMUNOLOGY | viral load | ORGAN TRANSPLANT RECIPIENTS | POLYMERASE-CHAIN-REACTION | IN-VIVO | DISEASE | EBV | post-transplantation lymphoproliferative disorders | T-CELLS | Cytokines - metabolism | Epstein-Barr Virus Infections - virology | Epstein-Barr Virus Infections - immunology | Herpesvirus 4, Human - physiology | Humans | Lymphoproliferative Disorders - virology | Herpesvirus 4, Human - immunology | DNA, Viral - analysis | Lymphoproliferative Disorders - complications | Lymphoproliferative Disorders - immunology | Viral Load | Antigens, Viral - immunology | B-Lymphocytes - immunology | Organ Transplantation - adverse effects | Hematopoietic Stem Cell Transplantation - adverse effects | Lymphoma, B-Cell - immunology | B-Lymphocytes - virology | Epstein-Barr Virus Infections - complications | Lymphoma, B-Cell - virology | Virus Activation | Cytokines - immunology | Virus diseases | Proteins | Lymphocytes | Stem cells | Transplantation | Health aspects | Hematopoietic stem cells
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7. Full Text Short-term inhibition of TERT induces telomere length-independent cell cycle arrest and apoptotic response in EBV-immortalized and transformed B cells
by Celeghin, Andrea and Giunco, Silvia and Freguja, Riccardo and Zangrossi, Manuela and Nalio, Silvia and Dolcetti, Riccardo and De Rossi, Anita
Cell death & disease, ISSN 2041-4889, 12/2016, Volume 7, Issue 12, pp. e2562 - e2562
Besides its canonical role in stabilizing telomeres, telomerase reverse transcriptase (TERT) may promote tumorigenesis through extra-telomeric functions. The... 
DNA-DAMAGE RESPONSES | CANCER-CELLS | OXIDATIVE STRESS | ACTIVATION | LEUKEMIA-CELLS | DOWN-REGULATION | LYTIC CYCLE | DEATH | EPSTEIN-BARR-VIRUS | LYMPHOCYTES | CELL BIOLOGY | Aminobenzoates | Cell Survival - drug effects | Ataxia Telangiectasia Mutated Proteins - metabolism | Apoptosis - drug effects | Humans | Vidarabine - analogs & derivatives | Telomere - drug effects | Naphthalenes | B-Lymphocytes - drug effects | Vidarabine - pharmacology | Signal Transduction - drug effects | Cell Cycle Checkpoints - drug effects | Cyclophosphamide - pharmacology | B-Lymphocytes - virology | Telomerase - metabolism | S Phase - drug effects | Telomere - metabolism | Histones - metabolism | Telomerase - antagonists & inhibitors | Herpesvirus 4, Human - metabolism | Telomere Homeostasis - drug effects | B-Lymphocytes - metabolism | Cell Line, Transformed | Cellular biology | Telomerase | Cell cycle | Apoptosis | Original
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8. Full Text Post-transplant lymphoproliferative disorders: From epidemiology to pathogenesis-driven treatment
by Petrara, Maria Raffaella and Giunco, Silvia and Serraino, Diego and Dolcetti, Riccardo and De Rossi, Anita
Cancer Letters, ISSN 0304-3835, 2015, Volume 369, Issue 1, pp. 37 - 44
Highlights • PTLD represents the most severe complication of both hematopoietic stem cell and solid organ transplantations. • EBV is the main driver of PTLDs,... 
Hematology, Oncology and Palliative Medicine | EBV | Latent/lytic viral cycle | PTLD | Treatment | Inflammation/immune activation | Telomerase | B-LYMPHOCYTES | VIRAL GENE-EXPRESSION | LIVER-TRANSPLANTATION | PERIPHERAL-BLOOD | SINGLE-CENTER-EXPERIENCE | POLYMERASE-CHAIN-REACTION | ONCOLOGY | KIDNEY-TRANSPLANTATION | IMMUNE ACTIVATION | STEM-CELL TRANSPLANTATION | EPSTEIN-BARR-VIRUS | Antiviral Agents - pharmacology | Epstein-Barr Virus Infections - virology | Antiviral Agents - therapeutic use | Virus Latency | Herpesvirus 4, Human - physiology | Humans | Lymphoproliferative Disorders - virology | Postoperative Complications - epidemiology | Epstein-Barr Virus Infections - drug therapy | Lymphoproliferative Disorders - pathology | Epstein-Barr Virus Infections - pathology | Lymphoproliferative Disorders - epidemiology | Postoperative Complications - virology | Animals | Organ Transplantation - adverse effects | Hematopoietic Stem Cell Transplantation - adverse effects | Lymphoproliferative Disorders - drug therapy | Postoperative Complications - drug therapy | Telomerase - antagonists & inhibitors | Epstein-Barr Virus Infections - epidemiology | Postoperative Complications - pathology | Epidemiology | Antiviral agents | Viral proteins | Cell death | Immunotherapy | Stem cells | Transplantation of organs, tissues, etc | Transplantation | B cells | Hematopoietic stem cells | Polymerase chain reaction | Competition | Pediatrics | Transplants & implants | Pathogenesis | Lymphomas | Adults
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9. Full Text Plasticity of type I interferon-mediated responses in cancer therapy: From anti-tumor immunity to resistance
by Budhwani, Megha and Mazzieri, Roberta and Dolcetti, Riccardo
Frontiers in Oncology, ISSN 2234-943X, 08/2018, Volume 8, p. 322
The efficacy of several therapeutic strategies against cancer, including cytotoxic drugs, radiotherapy, targeted immunotherapies and oncolytic viruses, depend... 
Immune responses | Tumor microenvironment | Cancer immunotherapy | Interferons | Resistance mechanisms | HEPATOCELLULAR-CARCINOMA CELLS | ACQUIRED-RESISTANCE | TUMOR-CELLS | resistance mechanisms | immune responses | CHRONIC MYELOID-LEUKEMIA | NEGATIVE BREAST-CANCER | PHASE-III TRIAL | interferons | UNFOLDED PROTEIN RESPONSE | ONCOLOGY | cancer immunotherapy | GENE-EXPRESSION | tumor microenvironment | VESICULAR STOMATITIS-VIRUS | NF-KAPPA-B | Care and treatment | Innovations | Cellular signal transduction | Genetic aspects | Interferon | Drug resistance | Health aspects | Cancer
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10. Full Text Lymphomas occurring specifically in HIV-infected patients: From pathogenesis to pathology
by Gloghini, Annunziata and Dolcetti, Riccardo and Carbone, Antonino
Seminars in Cancer Biology, ISSN 1044-579X, 2013, Volume 23, Issue 6, pp. 457 - 467
Abstract Lymphomas that develop in HIV positive patients are predominantly aggressive B-cell malignancies. The most common HIV-associated lymphomas are Burkitt... 
Hematology, Oncology and Palliative Medicine | EBV | Pathology | Pathogenesis | KSHV | HIV-associated lymphomas | HIV-lymphoma | SARCOMA-ASSOCIATED HERPESVIRUS | PRIMARY EFFUSION LYMPHOMA | B-CELL DIFFERENTIATION | ACTIVE-ANTIRETROVIRAL-THERAPY | KAPOSIS-SARCOMA | ONCOLOGY | PLASMABLASTIC LYMPHOMA | NON-HODGKIN-LYMPHOMA | SOLID LYMPHOMAS | GENE-EXPRESSION PROFILE | EPSTEIN-BARR-VIRUS | Burkitt Lymphoma - virology | Herpesvirus 8, Human - pathogenicity | Humans | Lymphoma, AIDS-Related - pathology | HIV Infections - complications | Herpesvirus 4, Human - pathogenicity | Sarcoma, Kaposi - virology | Castleman Disease - virology | Sarcoma, Kaposi - pathology | Lymphoma, AIDS-Related - virology | Sarcoma | Immunotherapy | Development and progression | HIV patients | Lymphomas | HIV (Viruses) | Health aspects | HIV infection
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11. Full Text A lymphomagenic role for HIV beyond immune suppression?
by Dolcetti, Riccardo and Gloghini, Annunziata and Caruso, Arnaldo and Carbone, Antonino
Blood, ISSN 0006-4971, 03/2016, Volume 127, Issue 11, pp. 1403 - 1409
Despite the immune reconstitution promoted by combined antiretroviral therapy (cART), lymphomas still represent the most common type of cancer in HIV-infected... 
UNITED-STATES | B-CELL LYMPHOMA | IMMUNODEFICIENCY-VIRUS | PRIMARY EFFUSION LYMPHOMA | AIDS-RELATED LYMPHOMAS | EXPRESSION PROFILE | NON-HODGKIN-LYMPHOMA | INFECTED PATIENTS | ACTIVE-ANTIRETROVIRAL-THERAPY | HEMATOLOGY | TUMOR MICROENVIRONMENT | gag Gene Products, Human Immunodeficiency Virus - physiology | Humans | Lymphoma, AIDS-Related - etiology | Lymphoma, AIDS-Related - pathology | Gene Expression Regulation, Neoplastic | Tumor Microenvironment | Gene Expression Profiling | Genes, gag | B-Lymphocytes - virology | Lymphoma, B-Cell - virology | Clone Cells | B-Lymphocytes - pathology | Lymphoma, B-Cell - etiology | gag Gene Products, Human Immunodeficiency Virus - genetics | Lymphoma, AIDS-Related - virology | Lymphocyte Activation | HIV Antigens - physiology | Mice, Transgenic | HIV - pathogenicity | Lymphoma, AIDS-Related - classification | Animals | HIV Antigens - genetics | Germinal Center - virology | HIV - genetics | Mice | Immunocompromised Host | Cell Transformation, Viral | Review
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12. Full Text Immunotherapy for EBV-associated malignancies
by Merlo, Anna and Turrini, Riccardo and Dolcetti, Riccardo and Zanovello, Paola and Rosato, Antonio
International Journal of Hematology, ISSN 0925-5710, 3/2011, Volume 93, Issue 3, pp. 281 - 293
Since 1995 to date, more than 250 patients with EBV-related diseases received virus-specific CTL. Cell therapy proved to be safe and effective, and achieved... 
NPC | Medicine & Public Health | Hematology | EBV | Oncology | PTLD | CTL | CORD BLOOD | CYTOTOXIC T-LYMPHOCYTES | NASOPHARYNGEAL CARCINOMA | HODGKINS-DISEASE | ADOPTIVE TRANSFER | NUCLEAR ANTIGEN 1 | IN-VIVO EXPANSION | STEM-CELL TRANSPLANTATION | HEMATOLOGY | POSTTRANSPLANT LYMPHOPROLIFERATIVE DISEASE | EPSTEIN-BARR-VIRUS | Hodgkin Disease - virology | T-Lymphocytes, Cytotoxic - immunology | Nasopharyngeal Carcinoma | Carcinoma | Epstein-Barr Virus Infections - immunology | Humans | Nasopharyngeal Neoplasms - therapy | Nasopharyngeal Neoplasms - virology | Clinical Trials as Topic | Adoptive Transfer | Herpesvirus 4, Human | T-Lymphocytes, Cytotoxic - transplantation | Epstein-Barr Virus Infections - therapy | Hodgkin Disease - therapy | Nasopharyngeal Neoplasms - immunology | Hodgkin Disease - immunology | Virus diseases | Antigens | Analysis | Immunotherapy | Stem cells | Transplantation of organs, tissues, etc | Lymphomas | Transplantation | T cells | Cancer | Nasopharyngeal carcinoma | Reviews | Immunoproliferative diseases | Prophylaxis | Chronic infection | Clinical trials | Cytotoxicity | Remission | Lymphocytes T | Malignancy | Hodgkin's disease
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13. Full Text The impact of EBV and HIV infection on the microenvironmental niche underlying Hodgkin lymphoma pathogenesis
by Carbone, Antonino and Gloghini, Annunziata and Caruso, Arnaldo and De Paoli, Paolo and Dolcetti, Riccardo
International Journal of Cancer, ISSN 0020-7136, 03/2017, Volume 140, Issue 6, pp. 1233 - 1245
The pathogenesis of classical Hodgkin lymphoma (cHL) is still enigmatic, largely because its tumor cells, the so‐called Hodgkin and Reed–Stenberg (HRS) cells,... 
microenvironment | classical Hodgkin lymphoma | HIV‐associated Hodgkin lymphoma | pathogenesis | EBV‐associated Hodgkin lymphoma | Hodgkin lymphoma | EBV-associated Hodgkin lymphoma | HIV-associated Hodgkin lymphoma | REED-STERNBERG CELLS | CENTER B-CELLS | IMMUNODEFICIENCY-VIRUS | CLASSICAL HODGKIN | ONCOLOGY | MEMBRANE-PROTEIN 1 | REGULATORY T-CELLS | MONOCYTE-DERIVED MACROPHAGES | GENE-EXPRESSION | TUMOR-ASSOCIATED MACROPHAGES | EPSTEIN-BARR-VIRUS | Hodgkin Disease - virology | Antigens, CD - immunology | Antigens, CD - biosynthesis | Fibroblasts - physiology | Hodgkin Disease - pathology | Virus Latency | Humans | Lymphoma, AIDS-Related - etiology | Lymphoma, AIDS-Related - pathology | Neoplasm Proteins - physiology | Gene Expression Regulation, Neoplastic | Tumor Microenvironment | Viral Matrix Proteins - physiology | Cytokines - physiology | Hodgkin Disease - etiology | B-Lymphocyte Subsets - immunology | Immunocompetence | B-Lymphocyte Subsets - virology | Lymphoma, AIDS-Related - virology | Macrophages - physiology | Epstein-Barr Virus Infections - physiopathology | Epstein-Barr Virus Infections - virology | Signal Transduction | Lymphocyte Activation | Epstein-Barr Virus Infections - immunology | Hodgkin Disease - classification | Lymphoma, AIDS-Related - immunology | Discoidin Domain Receptor 1 - physiology | Comparative Genomic Hybridization | Models, Biological | Hodgkin Disease - immunology | Reed-Sternberg Cells - virology | Lymphocytes, Tumor-Infiltrating - immunology | Virus diseases | Analysis | Lymphomas | Epstein-Barr virus | HIV (Viruses) | Health aspects | HIV infection | Infections | Pathogenesis | Human immunodeficiency virus--HIV
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