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animals (8) 8
cadasil (8) 8
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notch3 (5) 5
pathogenesis (5) 5
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notch3 protein (2) 2
oxyhemoglobin-induced suppression (2) 2
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receptors, notch - metabolism (2) 2
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reverse transcriptase polymerase chain reaction (2) 2
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tissue inhibitor of metalloproteinase-3 - metabolism (2) 2
vascular diseases (2) 2
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voltage-gated potassium channel (2) 2
4-aminopyridine - pharmacology (1) 1
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Annals of Neurology, ISSN 0364-5134, 03/2016, Volume 79, Issue 3, pp. 387 - 403
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2015, Volume 112, Issue 7, pp. E796 - E805
Journal Article
Journal Article
Brain, ISSN 0006-8950, 06/2013, Volume 136, Issue 6, pp. 1830 - 1845
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, or CADASIL, one of the most common inherited small vessel diseases... 
Journal Article
Annals of Neurology, ISSN 0364-5134, 08/2018, Volume 84, Issue 2, pp. 246 - 259
ObjectiveCADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy), caused by dominant mutations in the NOTCH3... 
Immunohistochemistry | Brain | Phenotypes | Deposits | Pathogenesis | Vasodilators | Medical treatment | Blood vessels | Electron microscopy | Doppler effect | Substantia alba | Leukoencephalopathy | Blood | Arteries | Blood flow | Cerebral blood flow | Immunotherapy | Monoclonal antibodies | Affinity | Topical application | Mutation | Lesions | Deposition | Recombinant
Journal Article
Journal Article
Annals of Neurology, ISSN 0364-5134, 08/2018, Volume 84, Issue 2, pp. 246 - 259
Journal Article
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 01/2013, Volume 33, Issue 1, pp. 76 - 86
OBJECTIVE—Notch3 is critically important for the structure and myogenic response of distal arteries, particularly of cerebral arteries. However, signaling... 
smooth muscle cell | cerebrovasculature | transcriptome | myogenic response | Notch3 | CELLS | MEMBRANE | KV1 CHANNELS | VASCULAR SMOOTH-MUSCLE | AMPA RECEPTORS | IN-VIVO | PERIPHERAL VASCULAR DISEASE | MICE | CEREBRAL-ARTERIES | HEMATOLOGY | EXPRESSION | RECEPTOR-BINDING PROTEIN | Muscle, Smooth, Vascular - metabolism | Receptors, Notch - metabolism | Nerve Tissue Proteins - deficiency | Male | Receptors, Notch - genetics | Gene Expression Profiling | Vasodilation | Alanine - analogs & derivatives | Kv1.5 Potassium Channel - genetics | Myocytes, Smooth Muscle - drug effects | Receptors, Notch - deficiency | Immunoglobulin J Recombination Signal Sequence-Binding Protein - genetics | Myocytes, Smooth Muscle - metabolism | Alanine - pharmacology | Muscle, Smooth, Vascular - drug effects | Vasoconstrictor Agents - pharmacology | Immunoglobulin J Recombination Signal Sequence-Binding Protein - metabolism | Vasodilator Agents - pharmacology | Signal Transduction | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Gene Expression Regulation | Reverse Transcriptase Polymerase Chain Reaction | Nerve Tissue Proteins - genetics | Vasoconstriction - drug effects | Mice, Knockout | Azepines - pharmacology | Nerve Tissue Proteins - metabolism | Carrier Proteins - genetics | Amyloid Precursor Protein Secretases - metabolism | Animals | Carrier Proteins - metabolism | Cerebral Arteries - metabolism | Kv1.5 Potassium Channel - metabolism | Receptor, Notch3 | Mice | Muscle, Smooth, Vascular - growth & development | Amyloid Precursor Protein Secretases - antagonists & inhibitors | Index Medicus
Journal Article
Annals of Neurology, ISSN 0364-5134, 03/2016, Volume 79, Issue 3, pp. 387 - 403
Journal Article
Brain, ISSN 0006-8950, 06/2013, Volume 136, Issue 6, pp. 1830 - 1845
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, or CADASIL, one of the most common inherited small vessel diseases... 
CADASIL | cerebrovasculature | extracellular matrix proteins | Original | protein aggregation | Notch3
Journal Article
The Journal of pathology, 12/2017
Mutations in the α1 (COL4A1) or α2 (COL4A2) chains of collagen type IV, a major component of the vascular basement membrane, cause intracerebral haemorrhages... 
Journal Article